Karsten KonigSummaryAffiliation: Saarland University Country: Germany Publications
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Publications
Clinical multiphoton tomographyKarsten Konig
Faculty of Mechatronics and Physics, Saarland University, Campus, 66123 Saarbrucken, Germany
J Biophotonics 1:13-23. 2008..So far, more than 500 patients and volunteers in Europe, Asia, and Australia have been investigated with these novel molecular imaging tools...
Multiphoton excitation characteristics of cellular fluorophores of human skin in vivoHans Georg Breunig
JenLab GmbH, Campus A1 2, 66123 Saarbrucken, Germany
Opt Express 18:7857-71. 2010..The analysis of the measurements is supplemented by additional measurements of fluorescence lifetime imaging and signal-decay curves by time-correlated single-photon counting...
Combined in vivo multiphoton and CARS imaging of healthy and disease-affected human skinHans Georg Breunig
JenLab GmbH, Campus D1 2, 66123 Saarbrucken, and Schillerstr 1, 07745, Jena, Germany
Microsc Res Tech 75:492-8. 2012..As an example for medical imaging, we investigated healthy and psoriasis-affected human skin with both image modalities in vivo and found indications for different lipid distributions on the cellular level...
Nanosurgery of cells and chromosomes using near-infrared twelve-femtosecond laser pulsesAisada Uchugonova
Department of Biophotonics and Laser Technology, Saarland University, Campus A51, 66123 Saarbruecken, Germany
J Biomed Opt 17:101502. 2012..These studies demonstrate the potential of extreme ultrashort femtosecond laser pulses at low mean milliwatt powers for sub-100 nm surgery of cells and cellular organelles...
Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer-cell anchorage and shapeAisada Uchugonova
AntiCancer Inc, San Diego, CA, USA
J Cell Biochem 114:99-102. 2013..These results suggest a new paradigm for a stromal element of tumors: their role in maintaining anchorage and shape of cancer cells that may enable them to proliferate...
Clinical application of multiphoton tomography in combination with high-frequency ultrasound for evaluation of skin diseasesKarsten Konig
JenLab GmbH, Schillerstraße 1, 07745 Jena and Campus A1 2, 66123 Saarbrucken, Germany
J Biophotonics 3:759-73. 2010..The combination of ultrasound and MPT opens novel synergistic possibilities in diagnostics of skin diseases with a special focus on the early detection of skin cancer as well as the evaluation of treatments...
Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery researchKarsten Konig
Department of Biophotonics and Laser Technology, Saarland University, Saarbruecken, Germany
Adv Drug Deliv Rev 63:388-404. 2011..These diverse applications highlight the capacity for multiphoton tomography and femtosecond laser nanoprocessing tools to advance drug delivery research...
