Carol Harty

Summary

Affiliation: Saarland University
Country: Germany

Publications

  1. pmc The Sec63p J-domain is required for ERAD of soluble proteins in yeast
    Christina Servas
    Department of Microbiology, Faculty of Natural Sciences and Technology VIII, Saarland University, Saarbrucken, Germany
    PLoS ONE 8:e82058. 2013
  2. ncbi request reprint ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7
    Thomas Tretter
    Department of Microbiology, Faculty of Natural Sciences and Technology VIII, Saarland University, Campus A1, 5, 66123 Saarbrucken, Germany
    BMC Cell Biol 14:56. 2013
  3. pmc N-acetylation and phosphorylation of Sec complex subunits in the ER membrane
    Christina Soromani
    Department of Clinical Biochemistry, University College London Hospital, London, UK
    BMC Cell Biol 13:34. 2012
  4. pmc Analysis of Sec61p and Ssh1p interactions in the ER membrane using the split-ubiquitin system
    Carol Harty
    Cambridge Institute for Medical Research, Hills Road, Cambridge CB2 2XY, UK
    BMC Cell Biol 14:14. 2013

Collaborators

Detail Information

Publications4

  1. pmc The Sec63p J-domain is required for ERAD of soluble proteins in yeast
    Christina Servas
    Department of Microbiology, Faculty of Natural Sciences and Technology VIII, Saarland University, Saarbrucken, Germany
    PLoS ONE 8:e82058. 2013
    ..In contrast to mammalian cells where SEC63 expression levels affect steady-state levels of multi-spanning transmembrane proteins, the sec63 J-domain mutant was only defective in ERAD of soluble substrates. ..
  2. ncbi request reprint ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7
    Thomas Tretter
    Department of Microbiology, Faculty of Natural Sciences and Technology VIII, Saarland University, Campus A1, 5, 66123 Saarbrucken, Germany
    BMC Cell Biol 14:56. 2013
    ..The mechanisms of channel opening for the different modes of translocation are not understood so far, but the position of the large ER-lumenal loop 7 of Sec61p suggests a decisive role...
  3. pmc N-acetylation and phosphorylation of Sec complex subunits in the ER membrane
    Christina Soromani
    Department of Clinical Biochemistry, University College London Hospital, London, UK
    BMC Cell Biol 13:34. 2012
    ..Little is known about the biogenesis and regulation of individual Sec complex subunits...
  4. pmc Analysis of Sec61p and Ssh1p interactions in the ER membrane using the split-ubiquitin system
    Carol Harty
    Cambridge Institute for Medical Research, Hills Road, Cambridge CB2 2XY, UK
    BMC Cell Biol 14:14. 2013
    ..Generation of fusion proteins is, however, rife with problems, and particularly in transmembrane proteins often disturbs topology, structure and function...