C M Freitag

Summary

Affiliation: Saarland University
Country: Germany

Publications

  1. ncbi Imitation and language abilities in adolescents with Autism Spectrum Disorder without language delay
    Christine M Freitag
    Dept of Child and Adolescent Psychiatry, Saarland University Hospital, 66421 Homburg, Saar, Germany
    Eur Child Adolesc Psychiatry 15:282-91. 2006
  2. ncbi The genetics of autistic disorders and its clinical relevance: a review of the literature
    C M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Mol Psychiatry 12:2-22. 2007
  3. ncbi Quantitative assessment of neuromotor function in adolescents with high functioning autism and Asperger Syndrome
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, 66421 Homburg Saar, Germany
    J Autism Dev Disord 37:948-59. 2007
  4. ncbi Interaction of serotonergic and noradrenergic gene variants in panic disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Psychiatr Genet 16:59-65. 2006
  5. ncbi [The genetics of autistic disorders]
    Christine M Freitag
    Klinik für Kinder und Jugendpsychiatrie, Universitatsklinikum des Saarlandes, Homburg
    Z Kinder Jugendpsychiatr Psychother 36:7-14; quiz 14-5. 2008
  6. doi Perception of biological motion in autism spectrum disorders
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Neuropsychologia 46:1480-94. 2008
  7. ncbi Behavioral comorbidity differs in subtypes of enuresis and urinary incontinence
    Susanne Zink
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Saarbrucken, Saarland, Germany
    J Urol 179:295-8; discussion 298. 2008
  8. ncbi Neuromotor development in nocturnal enuresis
    Alexander Von Gontard
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg Saar, Germany
    Dev Med Child Neurol 48:744-50. 2006
  9. pmc Total brain volume and corpus callosum size in medication-naïve adolescents and young adults with autism spectrum disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Biol Psychiatry 66:316-9. 2009
  10. doi Adenosine A(2A) receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Johann Wolfgang Goethe Universitat, Deutschordenstrasse 50, 60528 Frankfurt am Main, Germany
    Eur Child Adolesc Psychiatry 19:67-74. 2010

Collaborators

Detail Information

Publications26

  1. ncbi Imitation and language abilities in adolescents with Autism Spectrum Disorder without language delay
    Christine M Freitag
    Dept of Child and Adolescent Psychiatry, Saarland University Hospital, 66421 Homburg, Saar, Germany
    Eur Child Adolesc Psychiatry 15:282-91. 2006
    ..It has been hypothesized that imitation abilities might be precursors of language abilities in young children with autism. No study on imitation and language abilities in adolescents with ASD has been performed to date...
  2. ncbi The genetics of autistic disorders and its clinical relevance: a review of the literature
    C M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Mol Psychiatry 12:2-22. 2007
    ..Cytogenetic and molecular genetic studies will be presented in detail, and the possibly involved aetiopathological pathways will be described. Implications of the different genetic findings for genetic counselling will be mentioned...
  3. ncbi Quantitative assessment of neuromotor function in adolescents with high functioning autism and Asperger Syndrome
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, 66421 Homburg Saar, Germany
    J Autism Dev Disord 37:948-59. 2007
    ..Motor impairment in children with Asperger Syndrome (AS) or High functioning autism (HFA) has been reported previously. This study presents results of a quantitative assessment of neuromotor skills in 14-22 year old HFA/AS...
  4. ncbi Interaction of serotonergic and noradrenergic gene variants in panic disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Psychiatr Genet 16:59-65. 2006
    ....
  5. ncbi [The genetics of autistic disorders]
    Christine M Freitag
    Klinik für Kinder und Jugendpsychiatrie, Universitatsklinikum des Saarlandes, Homburg
    Z Kinder Jugendpsychiatr Psychother 36:7-14; quiz 14-5. 2008
    ..Important differential diagnoses will be described. The results of genetic studies are especially relevant with regard to genetic counselling for affected families...
  6. doi Perception of biological motion in autism spectrum disorders
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Neuropsychologia 46:1480-94. 2008
    ....
  7. ncbi Behavioral comorbidity differs in subtypes of enuresis and urinary incontinence
    Susanne Zink
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Saarbrucken, Saarland, Germany
    J Urol 179:295-8; discussion 298. 2008
    ..The aim of this prospective study is to describe the association of comorbid behavioral and somatic factors in children with different forms of nocturnal enuresis and daytime incontinence referred to a tertiary center...
  8. ncbi Neuromotor development in nocturnal enuresis
    Alexander Von Gontard
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg Saar, Germany
    Dev Med Child Neurol 48:744-50. 2006
    ..In addition to a maturational deficit of the brainstem, it is proposed that there is a possible maturational deficit of the motor cortex circuitry and related cortical areas in children with nocturnal enuresis...
  9. pmc Total brain volume and corpus callosum size in medication-naïve adolescents and young adults with autism spectrum disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Biol Psychiatry 66:316-9. 2009
    ..Similarly, studies of corpus callosum (CC) area in ASD differ with regard to inclusion criteria, age, and IQ...
  10. doi Adenosine A(2A) receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Johann Wolfgang Goethe Universitat, Deutschordenstrasse 50, 60528 Frankfurt am Main, Germany
    Eur Child Adolesc Psychiatry 19:67-74. 2010
    ..Findings point toward a possible mediating role of ADORA2A variants on phenotypic expression in ASD that need to be replicated in a larger sample...
  11. doi Phenotypic and measurement influences on heritability estimates in childhood ADHD
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, JW Goethe University, Deutschordenstrasse 50, Frankfurt am Main, Germany
    Eur Child Adolesc Psychiatry 19:311-23. 2010
    ....
  12. doi Association of a functional variant of neuronal nitric oxide synthase gene with self-reported impulsiveness, venturesomeness and empathy in male offenders
    Wolfgang Retz
    Neurocentre, Institute for Forensic Psychology and Psychiatry, Saarland University Hospital, Homburg, Saar, Germany
    J Neural Transm 117:321-4. 2010
    ..The findings give additional evidence that NOS-I is involved in the regulation of impulsive personality traits and support the notion that the NOS1 gene takes part in the regulation of social behavior...
  13. ncbi Neurophysiology of nocturnal enuresis: evoked potentials and prepulse inhibition of the startle reflex
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg Saar, Germany
    Dev Med Child Neurol 48:278-84. 2006
    ..Differences in VEP latencies might point towards functional cortical differences in children with a family history of nocturnal enuresis...
  14. pmc Genetics of autistic disorders: review and clinical implications
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Johann Wolfgang Goethe University, Deutschordenstrasse 50, Frankfurt am Main, Germany
    Eur Child Adolesc Psychiatry 19:169-78. 2010
    ..Implications of the different genetic findings for genetic counselling and genetic testing at present will be described. The article ends with a prospectus on future directions...
  15. doi Cortisol awakening response in healthy children and children with ADHD: impact of comorbid disorders and psychosocial risk factors
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Psychoneuroendocrinology 34:1019-28. 2009
    ..In addition, current adverse parenting conditions, family conflicts, and acute life events were associated with mean increase in CAR, emphasizing the role of psychosocial risk factors in mediating HPA axis activity in children with ADHD...
  16. ncbi Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women
    Katharina Domschke
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 7:183-8. 2004
    ..Our data support a role of the 472G/A (V158M) COMT polymorphism or a nearby locus in the pathogenesis of panic disorder in women...
  17. ncbi Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment
    Andreas Reif
    Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Neuropsychopharmacology 32:2375-83. 2007
    ..These findings indicate complex interactions between genetic variation of the serotonergic circuitry and environmental factors arguing against simplistic, mono-causal explanations of violent behavior...
  18. ncbi A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment
    Wolfgang Retz
    Institute for Forensic Psychology and Psychiatry, University of the Saarland, Homburg Saar, Germany
    Psychiatry Res 158:123-31. 2008
    ..The results support prior findings of association between ADHD and 5-HTTLPR LL-genotype and adverse childhood environment, and they underline the need for further investigation of gene by environment interaction with respect to ADHD...
  19. ncbi The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder
    Rainald Mossner
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    J Psychopharmacol 20:547-52. 2006
    ..The results of this first study of TPH2 in panic disorder argue against an importance of allelic variation of TPH2 in the pathogenesis of panic disorder with or without agoraphobia...
  20. ncbi A highly polymorphic poly-glutamine stretch in the potassium channel KCNN3 in migraine
    Rainald Mossner
    Department of Psychiatry, University of Wurzburg, Germany
    Headache 45:132-6. 2005
    ..Objective: The present study is designed to further elucidate the molecular genetic basis of migraine with and without aura...
  21. ncbi Norepinephrine transporter (NET) promoter and 5'-UTR polymorphisms: association analysis in panic disorder
    Yoo J Lee
    Department of Psychiatry, University of Munster, Albert Schweitzer Str 11, D 48149 Munster, Germany
    Neurosci Lett 377:40-3. 2005
    ..05; T/C (rs2242446): p < 0.01). While our data do not support a major function of the NET gene in the development of panic disorder, it may play a role in the subgroup of panic disorder without agoraphobia...
  22. ncbi A functional polymorphism in the IL-10 promoter influences the response after vaccination with HBsAg and hepatitis A
    Thomas Höhler
    Department of Internal Medicine, Johannes Gutenberg University, Mainz, Germany
    Hepatology 42:72-6. 2005
    ..In conclusion, genetic variability in the IL-10 promoter is an important modulator of the immune response against hepatitis viral antigens...
  23. ncbi Rare variants of the gene encoding the potassium chloride co-transporter 3 are associated with bipolar disorder
    Jobst Meyer
    Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Germany
    Int J Neuropsychopharmacol 8:495-504. 2005
    ..Our data strongly suggest that rare variants of SLC12A6 may represent risk factors for bipolar disorder...
  24. ncbi DTNBP1 (dysbindin) gene variants modulate prefrontal brain function in healthy individuals
    Andreas J Fallgatter
    Laboratory for Psychophysiology and Functional Imaging, Department of Psychiatry, University of Wurzburg, Wurzburg, Bavaria, Germany
    Neuropsychopharmacology 31:2002-10. 2006
    ..Future studies will have to address the relevance of this observation for patients with schizophrenias...
  25. ncbi A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder
    Christian Kissling
    Department of Psychiatry, Institute of Life Sciences, Swansea University, Swansea, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 147:333-8. 2008
    ..This is the first study suggesting that a polymorphism of a gene within the circadian "clock" mechanism is a direct or linked contributing factor in adult ADHD...
  26. pmc The functional Val158Met variant of the COMT gene is not associated with migraine with or without aura
    Rainald Mossner
    J Headache Pain 7:165-6. 2006