H Bonkhoff

Summary

Affiliation: Saarland University
Country: Germany

Publications

  1. ncbi request reprint Neuroendocrine differentiation in human prostate cancer. Morphogenesis, proliferation and androgen receptor status
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Ann Oncol 12:S141-4. 2001
  2. ncbi request reprint Progesterone receptor expression in human prostate cancer: correlation with tumor progression
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 48:285-91. 2001
  3. ncbi request reprint Estrogen receptor gene expression and its relation to the estrogen-inducible HSP27 heat shock protein in hormone refractory prostate cancer
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 45:36-41. 2000
  4. ncbi request reprint Differential expression of alpha 6 and alpha 2 very late antigen integrins in the normal, hyperplastic, and neoplastic prostate: simultaneous demonstration of cell surface receptors and their extracellular ligands
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Hum Pathol 24:243-8. 1993
  5. ncbi request reprint Neuroendocrine cells in benign and malignant prostate tissue: morphogenesis, proliferation, and androgen receptor status
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate Suppl 8:18-22. 1998
  6. ncbi request reprint Morphogenetic concepts of normal and abnormal growth in the human prostate
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Virchows Arch 433:195-202. 1998
  7. ncbi request reprint In situ hybridization analysis of genes coding collagen IV alpha1 chain, laminin beta1 chain, and S-laminin in prostate tissue and prostate cancer: increased basement membrane gene expression in high-grade and metastatic lesions
    C Pföhler
    Department of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 36:143-50. 1998
  8. ncbi request reprint Simultaneous detection of DNA fragmentation (apoptosis), cell proliferation (MIB-1), and phenotype markers in routinely processed tissue sections
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Virchows Arch 434:71-3. 1999
  9. ncbi request reprint Analytical molecular pathology of epithelial-stromal interactions in the normal and neoplastic prostate
    H Bonkhoff
    Department of Pathology, University of the Saarland, Homburg Saar, Germany
    Anal Quant Cytol Histol 20:437-42. 1998
  10. ncbi request reprint [Primary fallopian tube carcinoma. Report of a single case with review of the literature]
    M Friedrich
    Universitätsfrauenklinik und Poliklinik mit Hebammenlehranstalt Homburg Saar, Deutschland
    Gynakol Geburtshilfliche Rundsch 37:216-20. 1997

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Neuroendocrine differentiation in human prostate cancer. Morphogenesis, proliferation and androgen receptor status
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Ann Oncol 12:S141-4. 2001
    ..The frequent occurrence of neuroendocrine (NE) differentiation in common prostatic malignancies has attracted increasing attention in contemporary prostate cancer research...
  2. ncbi request reprint Progesterone receptor expression in human prostate cancer: correlation with tumor progression
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 48:285-91. 2001
    ..The recent discovery of the classical estrogen receptor alpha (ERalpha) in metastatic and recurrent prostatic adenocarcinoma suggests that estrogens are implicated in prostate cancer progression...
  3. ncbi request reprint Estrogen receptor gene expression and its relation to the estrogen-inducible HSP27 heat shock protein in hormone refractory prostate cancer
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 45:36-41. 2000
    ..To get more information on downstream events of estrogen signaling in these tumors, we investigated the relation between ERalpha gene expression, and the estrogen-inducible heat shock protein HSP27 in recurrent prostatic adenocarcinomas...
  4. ncbi request reprint Differential expression of alpha 6 and alpha 2 very late antigen integrins in the normal, hyperplastic, and neoplastic prostate: simultaneous demonstration of cell surface receptors and their extracellular ligands
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Hum Pathol 24:243-8. 1993
    ..These findings suggest that VLA-6 and VLA-2 receptors mediate attachment of tumor cells to neoplastic BM material, which, in turn, may endow these cells with an increased ability to invade the extracellular matrix...
  5. ncbi request reprint Neuroendocrine cells in benign and malignant prostate tissue: morphogenesis, proliferation, and androgen receptor status
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate Suppl 8:18-22. 1998
    ..Furthermore, the absence of proliferation activity may endow NE tumor cells with relative resistance toward cytotoxic drugs and radiation therapy...
  6. ncbi request reprint Morphogenetic concepts of normal and abnormal growth in the human prostate
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Virchows Arch 433:195-202. 1998
    ..Knowledge of morphogenesis and morphology is required in any scientific approach to BPH and prostate cancer...
  7. ncbi request reprint In situ hybridization analysis of genes coding collagen IV alpha1 chain, laminin beta1 chain, and S-laminin in prostate tissue and prostate cancer: increased basement membrane gene expression in high-grade and metastatic lesions
    C Pföhler
    Department of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 36:143-50. 1998
    ....
  8. ncbi request reprint Simultaneous detection of DNA fragmentation (apoptosis), cell proliferation (MIB-1), and phenotype markers in routinely processed tissue sections
    H Bonkhoff
    Institute of Pathology, University of the Saarland, Homburg Saar, Germany
    Virchows Arch 434:71-3. 1999
    ..It may be useful in studies of tissue kinetics in physiological and pathological processes...
  9. ncbi request reprint Analytical molecular pathology of epithelial-stromal interactions in the normal and neoplastic prostate
    H Bonkhoff
    Department of Pathology, University of the Saarland, Homburg Saar, Germany
    Anal Quant Cytol Histol 20:437-42. 1998
    ..To review recent data on epithelial-stromal interactions, recognized as playing an important role in prostatic growth in vitro...
  10. ncbi request reprint [Primary fallopian tube carcinoma. Report of a single case with review of the literature]
    M Friedrich
    Universitätsfrauenklinik und Poliklinik mit Hebammenlehranstalt Homburg Saar, Deutschland
    Gynakol Geburtshilfliche Rundsch 37:216-20. 1997
    ..The primary treatment remains surgical resection followed by adjuvant chemotherapy or radiation. Prognosis is poor, although long-term survivors have been reported...
  11. ncbi request reprint Expression of the human telomerase reverse transcriptase is not related to telomerase activity in normal and malignant renal tissue
    V Rohde
    Clinic of Urology and Pediatric Urology, University of the Saarland, Homburg Saar, Germany
    Clin Cancer Res 6:4803-9. 2000
    ..It seems more likely, that other mechanisms, such as posttranscriptional modification of hTERT or inactivation of telomerase inhibitors, are involved in the acquisition of enzyme activity...
  12. ncbi request reprint Differential expression of 5 alpha-reductase isoenzymes in the human prostate and prostatic carcinomas
    H Bonkhoff
    Instiute of Pathology, University of the Saarland, Homburg Saar, Germany
    Prostate 29:261-7. 1996
    ..Steroid 5 alpha-reductase is essential for the intracellular accumulation of dihydrotestosterone (DHT), which mediates androgen effects on target tissue...