Research Topics
Species | Michael StumpfSummaryAffiliation: RWTH Aachen Country: Germany Publications
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Detail Information
Publications
Increased distribution of collagen type III and reduced expression of matrix metalloproteinase 1 in patients with diverticular diseaseM Stumpf
Department of Surgery, Medical College, Rhenish Westphalian Technical University, Aachen, Germany
Int J Colorectal Dis 16:271-5. 2001..Further studies must focus on the complex interactions of several extracellular matrix components...
The surgical trauma of abdominal wall incision. A comparison of laparoscopic vs open surgery with three-dimensional stereographyM Stumpf
Department of Surgery, University Hospital, Rheinisch Westphälische Technische Hochschule RWTH, Pauwelsstrasse 30, 52057 Aachen, Germany
Surg Endosc 15:1147-9. 2001..The new technique of three-dimensional stereography makes it possible to describe and calculate the mobility of the abdominal wall and the nature of the underlying disturbances...
Collagen distribution and expression of matrix metalloproteinases 1 and 13 in patients with anastomotic leakage after large-bowel surgeryMichael Stumpf
Department of Surgery, Medical Faculty of Rhenish Westphalian Technical University, Pauwelsstrasse 30, 52074 Aachen, Germany
Langenbecks Arch Surg 386:502-6. 2002....
Zinc deficiency impairs wound healing of colon anastomosis in ratsMarcel Binnebösel
Department of Surgery, RWTH Aachen University Hospital, Pauwelsstr 30, 52074 Aachen, Germany
Int J Colorectal Dis 25:251-7. 2010..Anastomotic leakage is a relevant surgical complication. The aim of the study was to investigate the influence of a controlled preoperative zinc deficiency on the extracellular matrix composition of colon anastomosis...
Missing effects of zinc in a porcine model of recurrent endotoxemiaCarsten J Krones
Department of Surgery, Technical University of Aachen, Pauwelsstr 30, 52074 Aachen, Germany
BMC Surg 5:22. 2005..During CARS, anti-inflammatory cytokines depress the inflammatory response leading to secondary and opportunistic infections. Proved in vitro as well as in vivo, zinc's pro-inflammatory effect might overcome this depression...
Reduced expression of collagen type I and increased expression of matrix metalloproteinases 1 in patients with Crohn's diseaseMichael Stumpf
Department of Surgery, Technical University of Aachen, Aachen, Germany
J Invest Surg 18:33-8. 2005..Further studies have to be done to elucidate these interesting aspect of the pathogenesis in Crohn's disease...
Changes of the extracellular matrix as a risk factor for anastomotic leakage after large bowel surgeryMichael Stumpf
Department of Surgery, University Hospital, Medical Faculty of the Rhenish Westphalian Technical University Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
Surgery 137:229-34. 2005..This prospective study was initiated to test the hypothesis that preexisting disorders in the extracellular matrix (ECM) may be a factor influencing the onset of anastomotic wound healing complications...
Suture-free small bowel anastomoses using collagen fleece covered with fibrin glue in pigsMichael Stumpf
Department of Surgery, Medical Faculty of Rheinisch Westfalischen, Technical University, Aachen, Germany
J Invest Surg 22:138-47. 2009..This study was initiated to test a hypothesis that a reduction of suture material leading to suture-free glued intestinal anastomoses is feasible and enables an improved wound healing...
Collagen in colon diseaseMichael Stumpf
Department of Surgery, Medical Faculty, University Hospital, Rhenish Westphalian Technical University RWTH, Pauwelsstrasse 30, 52074 Aachen, Germany
Hernia 10:498-501. 2006..This concept could explain the well known situation where an anastomotic breakdown is observed, despite the absence of other known risk factors and after a technically correct anastomosis...
Effect of zinc pretreatment on pulmonary endothelial cells in vitro and pulmonary function in a porcine model of endotoxemiaCarsten Johannes Krones
Department of Surgery, The Technical University of Aachen, Aachen, Germany
J Surg Res 123:251-6. 2005..As protective effects of zinc are described in vitro as well as in vivo, this study investigates its impact on septic porcine pulmonary endothelial monolayers as well as on the pulmonary function of endotoxemic pigs...
Deleterious effect of zinc in a pig model of acute endotoxemiaCarsten Krones
Department of Surgery, Technical University of Aachen, Aachen, Germany
J Invest Surg 17:249-56. 2004..The same potentials characterizing zinc as a promising tool of prophylactic therapy in sepsis seem to ban its use during the acute phase...
Review of wound healing with reference to an unrepairable abdominal herniaKarsten Junge
Department of Surgery, RWTH Aachen, Germany
Eur J Surg 168:67-73. 2002..This stimulated us to review the biochemistry of wound repair. We studied the composition of his collagen and tried to find out whether it was intrinsically faulty or whether its fault had been caused by the medication he was taken...
