Research Topics
| Marco DasSummaryAffiliation: RWTH Aachen Country: Germany Publications
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Detail Information
Publications
Asbestos Surveillance Program Aachen (ASPA): initial results from baseline screening for lung cancer in asbestos-exposed high-risk individuals using low-dose multidetector-row CTMarco Das
Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany
Eur Radiol 17:1193-9. 2007..28% (8/187) at baseline screening with an additional large number of indeterminate pulmonary nodules. Low-dose MDCT proved to be feasible in this highly selected population...- Optimized image reconstruction for detection of deep venous thrombosis at multidetector-row CT venographyMarco Das
Department of Diagnostic Radiology, University Hospital, University of Technology RWTH, Pauwelsstr 30, 52074, Aachen, Germany
Eur Radiol 16:269-75. 2006..Median image quality was 2. Estimated effective dose ranged between 2.3 mSv and 11.8 mSv. Gaps in sequential protocols may lead to false negative results. Therefore, spiral scanning protocols for complete depiction of DVT are mandatory... - Small pulmonary nodules: effect of two computer-aided detection systems on radiologist performanceMarco Das
Department of Diagnostic Radiology, Institute of Medical Statistics, and Department of Occupational Health, Rheinisch Westfälische Technische Hochschule Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
Radiology 241:564-71. 2006..To prospectively compare the effects of two computer-aided detection (CAD) systems on the detection of small pulmonary nodules at multi-detector row computed tomography (CT) by using a consensus panel decision as the reference standard... - Accuracy of automated volumetry of pulmonary nodules across different multislice CT scannersMarco Das
Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52072 Aachen, Germany
Eur Radiol 17:1979-84. 2007..Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies... 
Performance evaluation of a computer-aided detection algorithm for solid pulmonary nodules in low-dose and standard-dose MDCT chest examinations and its influence on radiologistsM Das
Department of Diagnostic Radiology, RWTH Aachen University Hospital, Aachen, Germany
Br J Radiol 81:841-7. 2008..0001). In conclusion, CAD is beneficial in both low-dose and standard-dose settings. This may be beneficial in reducing false-negative diagnosis in lung cancer screening, standard chest examinations and the search for metastases...- Carotid plaque analysis: comparison of dual-source computed tomography (CT) findings and histopathological correlationM Das
Department of Diagnostic Radiology, RWTH Aachen University, Aachen, NRW, Germany
Eur J Vasc Endovasc Surg 38:14-9. 2009..Thus, the purpose of our study was to evaluate the findings of preoperative dual-source computed tomography (DSCT) of carotid plaque morphology and correlate these findings with histopathological findings... - Automated volumetry of solid pulmonary nodules in a phantom: accuracy across different CT scanner technologiesMarco Das
Department of Diagnostic Radiology, RWTH Aachen University, Aachen, Germany
Invest Radiol 42:297-302. 2007..The accuracy of automated volumetry for pulmonary nodules in a phantom using different CT scanner technologies from single-slice spiral CT (SSCT) to 64-slice multidetector-row CT (MDCT) was compared... - Individually adapted examination protocols for reduction of radiation exposure for 16-MDCT chest examinationsMarco Das
Department of Diagnostic Radiology, University Hospital, University of Technology RWTH, Pauwelsstrasse 30, D 52074 Aachen, Germany
AJR Am J Roentgenol 184:1437-43. 2005..The purpose of our study was to develop a simple protocol for reduction of radiation exposure without loss of diagnostic information in chest 16-MDCT... - Computer-aided detection of pulmonary embolism: influence on radiologists' detection performance with respect to vessel segmentsMarco Das
Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstr 30, 52072 Aachen, Germany
Eur Radiol 18:1350-5. 2008..0001). CAD performance at the lobar level was 87%, at the segmental 90% and at the subsegmental 77%. With the use of CAD for PE, the detection performance of radiologists can be improved... - Evaluation of automated attenuation-based tube current adaptation for coronary calcium scoring in MDCT in a cohort of 262 patientsGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Germany
Eur Radiol 17:1850-7. 2007..Automated attenuation-based tube current adaptation in coronary calcium scoring is technically feasible, can decrease patient dose, and reduces variation in image noise as a sign of improved dose usage... - Semiautomated versus manual evaluation of liver metastases treated by radiofrequency ablationSebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Aachen, Germany
J Vasc Interv Radiol 21:245-51. 2010..To determine the accuracy of semiautomated volume and density measurements of liver metastases from colorectal and breast cancer before and after radiofrequency (RF) ablation compared with manual evaluation... - Effect of different saline chaser volumes and flow rates on intravascular contrast enhancement in CT using a circulation phantomFlorian F Behrendt
Department of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany
Eur J Radiol 73:688-93. 2010..To evaluate the influence of different saline chaser volumes and different saline chaser flow rates on the intravascular contrast enhancement in MDCT... - Dose reduction for semi-automated volumetry of hepatic metastasis in MDCT studiesSebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Germany
Invest Radiol 45:77-81. 2010..To investigate the performance of semi-automated measurements (RECIST, volume) of hepatic metastases in multidetector-row computed tomography (MDCT) under normal-dose- and simulated low-dose-protocols... - The accuracy of 1- and 3-mm slices in coronary calcium scoring using multi-slice CT in vitro and in vivoGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
Eur Radiol 17:321-9. 2007.... - Global left ventricular function: assessment with dual-source CT versus conventional ventriculography in a porcine modelPhilipp Bruners
Applied Medical Engineering, Helmholtz Institute for Biomedical Engineering, Aachen, Germany
Acta Cardiol 64:311-9. 2009..The purpose of this study was to assess the global left ventricular function using retrospectively ECG-gated dual source computed tomography (DSCT) in comparison to conventional ventriculography... - Computer-aided measurements of pulmonary emphysema in chest multidetector-row spiral computed tomography: effect of image reconstruction parametersFlorian F Behrendt
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Aachen, Germany
J Comput Assist Tomogr 32:899-904. 2008..To evaluate the effect of different image reconstruction parameters on quantitative automated measurements of pulmonary emphysema in chest multidetector-row spiral computed tomography... - Coronary artery calcium scoring with multislice computed tomography: in vitro assessment of a low tube voltage protocolChristoph K Thomas
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
Invest Radiol 41:668-73. 2006..We sought to compare an 80-kVp coronary calcium scoring protocol with the standard protocol of 120 kVp in terms of accuracy and reproducibility and to assess its dose reduction potential... - Radiofrequency ablation of liver metastases-software-assisted evaluation of the ablation zone in MDCT: tumor-free follow-up versus local recurrent diseaseSebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
Cardiovasc Intervent Radiol 33:297-306. 2010..A new parameter (lnQ1//28/0(volume/RECIST/WHO/attenuation)) was introduced, which appears to be of prognostic value at early follow-up CT... - Semi-automated measurement of hyperdense, hypodense and heterogeneous hepatic metastasis on standard MDCT slices. Comparison of semi-automated and manual measurement of RECIST and WHO criteriaSebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Aachen, Germany
Eur Radiol 18:2456-65. 2008..94 (heterogeneous); WHO area: 0.95, 0.98, 0.93]. Semi-automatic measurement of hyperdense, hypodense and heterogeneous liver metastases showed reliable results on standard axial reconstructions in comparison to manual quantification... - Impact of different vein catheter sizes for mechanical power injection in CT: in vitro evaluation with use of a circulation phantomFlorian F Behrendt
Department of Diagnostic Radiology, University Hospital, RWTH, Aachen, Germany
Cardiovasc Intervent Radiol 32:25-31. 2009..In summary, intravenous catheters with sizes of 14-20 G are suitable for CT angiography using an injection protocol with a high flow rate and a high-iodine-concentration contrast medium... - Influence of a small field-of-view size on the detection of coronary artery calcifications with MSCT: in vitro and in vivo studyAndreas H Mahnken
Department of Diagnostic Radiology, Aachen University of Technology, Pauwelsstrasse 30, 52074, Aachen, Germany
Eur Radiol 16:358-64. 2006..The use of small FOV sizes resulted in an improved detection of coronary calcifications influencing the risk stratification for further cardiac events in MSCT coronary calcium scoring... - Semi-automated quantification of hepatic lesions in a phantomSebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Aachen, Germany
Invest Radiol 44:82-8. 2009..Thus, the purpose of our study was to assess the accuracy of semi-automated RECIST and volumetric measurements of liver lesions in a liver phantom with different CT acquisition parameters... - Influence of heart rate and temporal resolution on left-ventricular volumes in cardiac multislice spiral computed tomography: a phantom studyAndreas H Mahnken
Department of Diagnostic Radiology, RWTH Aachen University, Germany
Invest Radiol 41:429-35. 2006..We sought to investigate the influence of heart rate and temporal resolution on the assessment of left-ventricular (LV) function with multislice spiral computed tomography (CT)... - Dose reduction during CT fluoroscopy: phantom study of angular beam modulationChristian Hohl
Department of Diagnostic Radiology, University of Technology of Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
Radiology 246:519-25. 2008..To prospectively evaluate, in a phantom, the dose reductions achievable by using angular beam modulation (ABM) during computed tomographic (CT) fluoroscopy-guided thoracic interventions... - Introduction of a dedicated circulation phantom for comprehensive in vitro analysis of intravascular contrast material applicationFlorian F Behrendt
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Aachen, Germany
Invest Radiol 43:729-36. 2008..To develop a circulation phantom with physiologic circulation parameters, including a pulmonary and a body circulation for the evaluation of intravascular contrast material (CM) application... - Automated measurement of lymph nodes: a phantom studySebastian Keil
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
Eur Radiol 19:1079-86. 2009..81% to 9.20% (0.97-0.99) (RECIST) and from 8.16% to 22.66% (0.99-1.00) (volume). Regarding RECIST criteria and volume, automated evaluation of lymph nodes in a phantom demonstrated a high accuracy under varying MDCT parameters... - Effect of varying slice thickness on coronary calcium scoring with multislice computed tomography in vitro and in vivoGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH, Aachen, Aachen, Germany
Invest Radiol 40:695-9. 2005..To compare coronary calcium scoring results (calcium volume, calcium mass, Agatston score, and number of lesions) of different slice thicknesses using a 16-slice CT (MSCT) scanner... - Global left ventricular function in cardiac CT. Evaluation of an automated 3D region-growing segmentation algorithmGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
Eur Radiol 16:1117-23. 2006..2%. On the basis of a good contrast-enhanced data set, a left ventricular volume analysis using the new semi-automated region-growing segmentation algorithm is technically feasible, accurate and more time-effective... - Contrast enhancement in chest multidetector computed tomography: intraindividual comparison of 300 mg/ml versus 400 mg/ml iodinated contrast mediumFlorian F Behrendt
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Aachen, Germany
Acad Radiol 16:144-9. 2009..We sought to intraindividually compare intravascular contrast enhancement in multidector computed tomography (MDCT) of the chest using contrast media (CM) containing 300 and 400 mg iodine/ml... - Which Iodine concentration in chest CT?--a prospective study in 300 patientsGeorg Mühlenbruch
Department of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, Germany
Eur Radiol 18:2826-32. 2008..00019). Given identical iodine delivery rates of 1.3 g/s and iodine loads of 33 g, contrast media with concentrations of 300, 370 and 400 mg iodine/ml do not result in different intravascular enhancement in chest-CT... - Coronary calcium scoring using 16-row multislice computed tomography: nonenhanced versus contrast-enhanced studies in vitro and in vivoGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Germany
Invest Radiol 40:148-54. 2005..We sought to assess the agreement of coronary artery calcium score in nonenhanced and contrast-enhanced multislice-spiral computed tomography... - Variability of aortic valve calcification measurement with multislice spiral computed tomographyKarl M Ruhl
Department of Diagnostic Radiology, RWTH Aachen University, Germany
Invest Radiol 41:370-3. 2006..We sought to assess the variability of aortic valve calcifications (AVCs) regarding the reconstruction window at different heart phases using multislice-spiral computed tomography... - Quantitative prediction of contrast enhancement from test bolus data in cardiac MSCTAndreas H Mahnken
Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany
Eur Radiol 17:1310-9. 2007..Prediction of contrast enhancement in cardiac MSCT from test bolus data is feasible with a relatively small mean deviation; 80% of the predictions were within a range that might be acceptable for routine clinical application... - MDCT detection of mitral valve calcification: prevalence and clinical relevance compared with echocardiographyAndreas H Mahnken
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
AJR Am J Roentgenol 188:1264-9. 2007..The purpose of this study was to analyze the prevalence and clinical significance of mitral valve calcification incidentally detected on chest CT scans in comparison with echocardiography... - Assessment of global left and right ventricular function using dual-source computed tomography (DSCT) in comparison to MRI: an experimental study in a porcine modelPhilipp Bruners
Applied Medical Engineering, Helmholtz Institute for Biomedical Engineering, Aachen, Germany
Invest Radiol 42:756-64. 2007..We sought to evaluate the ability of retrospectively ECG-gated dual-source computed tomography (DSCT) to assess left (LV) and right ventricular (RV) functional parameters in comparison to 1.5 T magnetic resonance imaging (MRI)... - Evaluation of aortocoronary bypass stents with cardiac MDCT compared with conventional catheter angiographyGeorg Mühlenbruch
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
AJR Am J Roentgenol 188:361-9. 2007..The objective of our study was to determine the accuracy of 16-MDCT for evaluation of stent patency and in-stent stenosis in venous coronary bypass grafts... - Comparison of dual-source CT angiography and MR angiography in preoperative evaluation of intra- and extracranial vessels: a pilot studyGeorg Mühlenbruch
Department of Diagnostic and Interventional Radiology, RWTH Aachen University, Pauwelsstr 30, 52057 Aachen, Germany
Eur Radiol 20:469-76. 2010..DSCT and MRA may both be regarded as a reliable, fast, pre-interventional imaging investigation in patients with carotid artery stenosis... - Value of virtual tracheobronchoscopy and bronchography from 16-slice multidetector-row spiral computed tomography for assessment of suspected tracheobronchial stenosis in childrenDagmar Honnef
Department of Diagnostic Radiology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
Eur Radiol 16:1684-91. 2006..To evaluate the value of dose-reduced 16-slice multidetector-row spiral computed tomography (16-MDCT) using virtual tracheobronchoscopy (VTB) and virtual bronchography (VBG) in children with suspected tracheobronchial stenosis... - CT imaging in acute pulmonary embolism: diagnostic strategiesJoachim E Wildberger
Department of Diagnostic Radiology, University Hospital, University of Technology RWTH, Aachen, Germany
Eur Radiol 15:919-29. 2005..Using advanced multislice spiral CT technology, some practitioners have advocated CTA as the sole imaging tool for routine clinical assessment in suspected acute PE. This will simplify standards of practice in the near future... - Combined approach for a locked unilateral facet fracture-dislocation of the cervicothoracic junctionBernhard Schmidt-Rohlfing
Department of Orthopaedic and Trauma Surgery, Aachen University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany
Acta Orthop Belg 74:875-80. 2008..The authors felt that this three-column lesion at the cervicothoracic junction necessitated combined posterior-anterior stabilisation... - Radiation dose reduction to the male gonads during MDCT: the effectiveness of a lead shieldChristian Hohl
Department of Diagnositc Radiology, University of Technology of Aachen, Paulwelsstrasse 30, Aachen D 52057, Germany
AJR Am J Roentgenol 184:128-30. 2005..Our study was designed to quantify the effect of a standard gonad shield on the testicular radiation exposure due to scatter during routine abdominopelvic MDCT... - Virtual elastic sphere processing enables reproducible quantification of vessel stenosis at CT and MR angiographyFelix Gremse
Department of Experimental Molecular Imaging, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
Radiology 260:709-17. 2011..To develop and evaluate a user-friendly tool to enable efficient, accurate, and reproducible quantification of blood vessel stenosis in computed tomographic (CT) and magnetic resonance (MR) angiographic data sets... - Intraperitoneal application of rituximab in refractory mantle cell lymphoma with massive ascites resulting in local and systemic responseMartina Crysandt
Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Aachen, Germany
Eur J Haematol 79:546-9. 2007..In summary, we observed a sustained local and systemic response to intraperitoneal administration of rituximab in a patient with heavily pretreated advanced MCL... - Multislice CT angiographyU Joseph Schoepf
Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, MA 02115, Boston, USA
Eur Radiol 13:1946-61. 2003.... - Augmented reality visualization for CT-guided interventions: system description, feasibility, and initial evaluation in an abdominal phantomMarco Das
Dept of Radiology, Brigham and Women's Hosp, Harvard Medical School, Boston, Mass, USA
Radiology 240:230-5. 2006..On the basis of these results, AR visualization for CT-guided intervention appears feasible and allows intuitive and accurate lesion targeting in a phantom. Supplemental material: radiology.rsnajnls.org/cgi/content/full/2401040018/DC1.. - Pulmonary embolism: computer-aided detection at multidetector row spiral computed tomographyU Joseph Schoepf
Department of Radiology, Medical University of South Carolina, Charleston, SC 29425, USA
J Thorac Imaging 22:319-23. 2007..We aimed to evaluate the feasibility and performance of a computer-aided detection (CAD) tool for automated detection of segmental and subsegmental pulmonary emboli...