S Rust

Summary

Country: Germany

Publications

  1. ncbi Assignment of Tangier disease to chromosome 9q31 by a graphical linkage exclusion strategy
    S Rust
    Institute of Arteriosclerosis Research, University of Munster, Germany
    Nat Genet 20:96-8. 1998
  2. ncbi Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    S Rust
    Institut für Arterioskleroseforschung an der Westfälischen Wilhelms Universität Münster, Germany
    Nat Genet 22:352-5. 1999
  3. ncbi The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages
    T Engel
    Macrophage Metabolism, Institut für Arterioskleroseforschung, Westfalische Wilhelms Universitat, Domagkstrasse 3, 48149 Munster, Germany
    Biochem Biophys Res Commun 288:483-8. 2001
  4. ncbi The transforming growth factor-beta1 gene polymorphism (G915C) is not associated with systemic lupus erythematosus
    H Schotte
    Medizinische Klinik und Poliklinik B, Universitatsklinikum, Munster, Germany
    Lupus 12:86-92. 2003
  5. ncbi Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred
    A T Remaley
    National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 96:12685-90. 1999
  6. ncbi Genomic sequence and structure of the human ABCG1 (ABC8) gene
    S Lorkowski
    Institut für Arterioskleroseforschung, Westfalische Wilhelms Universitat Munster, Germany
    Biochem Biophys Res Commun 280:121-31. 2001
  7. ncbi Interleukin-6 promoter polymorphism (--174 G/C) in Caucasian German patients with systemic lupus erythematosus
    H Schotte
    Medizinische Klinik und Poliklinik B, Westfalische Wilhelms Universitat, Munster, Germany
    Rheumatology (Oxford) 40:393-400. 2001
  8. ncbi Association of the GPIa C807T and GPIIIa PlA1/A2 polymorphisms with premature myocardial infarction in men
    G Benze
    Institut fur Klinische Chemie und Laboratoriumsmedizin, Westfalische Wilhelms Universitat Munster, Munster, Germany
    Eur Heart J 23:325-30. 2002

Detail Information

Publications8

  1. ncbi Assignment of Tangier disease to chromosome 9q31 by a graphical linkage exclusion strategy
    S Rust
    Institute of Arteriosclerosis Research, University of Munster, Germany
    Nat Genet 20:96-8. 1998
    ..05 at D9S1784). We also provide evidence that TD may be due to a loss-of-function defect...
  2. ncbi Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    S Rust
    Institut für Arterioskleroseforschung an der Westfälischen Wilhelms Universität Münster, Germany
    Nat Genet 22:352-5. 1999
    ..An in-frame insertion-deletion in exon 12 was found in the second family. Our findings indicate that defects in ABC1, encoding a member of the ABC transporter superfamily, are the cause of TD...
  3. ncbi The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages
    T Engel
    Macrophage Metabolism, Institut für Arterioskleroseforschung, Westfalische Wilhelms Universitat, Domagkstrasse 3, 48149 Munster, Germany
    Biochem Biophys Res Commun 288:483-8. 2001
    ..6 kb in size on chromosome 11q23.3. Based on its structural features and an LXR/RXR-responsive regulation similar to the cellular lipid export protein ABCA1, we conclude that ABCG4 may be involved in macrophage lipid homeostasis...
  4. ncbi The transforming growth factor-beta1 gene polymorphism (G915C) is not associated with systemic lupus erythematosus
    H Schotte
    Medizinische Klinik und Poliklinik B, Universitatsklinikum, Munster, Germany
    Lupus 12:86-92. 2003
    ..Further studies are needed to corroborate the pathogenic role of TGF-beta1 in SLE patients and to identify the precise genetic elements controlling its production...
  5. ncbi Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred
    A T Remaley
    National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 96:12685-90. 1999
    ..These results will be useful in the future characterization of the structure and function of the ABC1 gene and the analysis of additional ABC1 mutations in patients with Tangier disease...
  6. ncbi Genomic sequence and structure of the human ABCG1 (ABC8) gene
    S Lorkowski
    Institut für Arterioskleroseforschung, Westfalische Wilhelms Universitat Munster, Germany
    Biochem Biophys Res Commun 280:121-31. 2001
    ..Nevertheless, both promoters responded in macrophages to stimulation by hydroxycholesterol and retinoic acid...
  7. ncbi Interleukin-6 promoter polymorphism (--174 G/C) in Caucasian German patients with systemic lupus erythematosus
    H Schotte
    Medizinische Klinik und Poliklinik B, Westfalische Wilhelms Universitat, Munster, Germany
    Rheumatology (Oxford) 40:393-400. 2001
    ..A biallelic polymorphism (--174 G/C) within the interleukin-6 (IL-6) promoter reportedly has functional importance through the modulation of IL-6 expression in vitro and in vivo...
  8. ncbi Association of the GPIa C807T and GPIIIa PlA1/A2 polymorphisms with premature myocardial infarction in men
    G Benze
    Institut fur Klinische Chemie und Laboratoriumsmedizin, Westfalische Wilhelms Universitat Munster, Munster, Germany
    Eur Heart J 23:325-30. 2002
    ..The T807 allele of the GPIa gene alone or in combination with the PlA2 allele had no major effect on premature myocardial infarction risk...