Kerstin Hellwig

Summary

Affiliation: Ruhr-University Bochum
Country: Germany

Publications

  1. pmc Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy
    Nadja Borisow
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 3:9. 2012
  2. pmc Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
    Sven Jarius
    Neurocure, Charite University Medicine Berlin, Berlin, Germany
    J Neuroinflammation 9:14. 2012
  3. doi request reprint A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    J Neurol Sci 307:164-5. 2011
  4. pmc Immunomodulation and postpartum relapses in patients with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Ther Adv Neurol Disord 2:7-11. 2009
  5. doi request reprint Parenthood and immunomodulation in patients with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    J Neurol 257:580-3. 2010
  6. doi request reprint Allergic and nonallergic delayed infusion reactions during natalizumab therapy
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Arch Neurol 65:656-8. 2008
  7. pmc Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients
    Stefanie Dahlhaus
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    J Neurol Neurosurg Psychiatry 84:1068-74. 2013
  8. doi request reprint Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy
    Ilya Ayzenberg
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    JAMA Neurol 70:394-7. 2013
  9. pmc Benefit of repetitive intrathecal triamcinolone acetonide therapy in predominantly spinal multiple sclerosis: prediction by upper spinal cord atrophy
    Carsten Lukas
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, St Josef Hospital, Ruhr University of Bochum, Bochum, Germany
    Ther Adv Neurol Disord 2:42-9. 2009
  10. doi request reprint Successful management of natalizumab-associated progressive multifocal leukoencephalopathy and immune reconstitution syndrome in a patient with multiple sclerosis
    Alexandra Schröder
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Arch Neurol 67:1391-4. 2010

Collaborators

  • Ralf Gold
  • Andrew Chan
  • Carsten Lukas
  • Ingo Kleiter
  • Thomas Muller
  • Ralf A Linker
  • Thomas Thum
  • Christos Krogias
  • Horst Neubauer
  • Christoph Globas
  • Jan Rexilius
  • Orhan Aktas
  • Tania Kuempfel
  • Stefanie Dahlhaus
  • Alexandra Schröder
  • Ilya Ayzenberg
  • Kalliopi Pitarokoili
  • Friedemann Paul
  • Sven Jarius
  • Aiden Haghikia
  • Nadja Borisow
  • Takashi Yamamura
  • Susanne Boehm
  • Robert Hoepner
  • Ortwin Adams
  • Christian Veauthier
  • Martin Liebetrau
  • Uwe K Zettl U
  • Bernhard Hemmer
  • Barbara Ettrich
  • Martin Marziniak
  • Angelika Holzmann
  • Corinna Trebst
  • Christian Wilke
  • Martin Stangel
  • Alexander Baraniskin
  • Imke Metz
  • Jan Dorr
  • Andrea Döring
  • Alexander Winkelmann
  • Peter Kern
  • Ulf Ziemann
  • Johannes Brettschneider
  • Klemens Ruprecht
  • Christoph Kleinschnitz
  • Klaus P Wandinger
  • Stefan Langel
  • Marius Ringelstein
  • Paulus S Rommer
  • Achim Berthele
  • Sabine Niehaus
  • Bernhard F Décard
  • Hayrettin Tumani
  • Reinhard Reuss
  • Arash Haghikia
  • Tobias Boettcher
  • Christian Geis
  • Brigitte Wildemann
  • Jörn P Sieb
  • Ulrich Hofstadt-van Oy
  • Kersten Guthke
  • Sven Schippling
  • Florian Lauda
  • Florian Then Bergh
  • Caspar F Pfueller
  • Hans P Hartung
  • Hannah Pellkofer
  • Jürgen H Faiss
  • Christoph Munch
  • Christian Zentner
  • Arthur Melms
  • Christoph A Mayer
  • Oliver Neuhaus
  • Frank Hoffmann
  • De Hyung Lee

Detail Information

Publications20

  1. pmc Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy
    Nadja Borisow
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 3:9. 2012
    ..Here, we provide an overview about the current state of knowledge regarding these issues...
  2. pmc Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
    Sven Jarius
    Neurocure, Charite University Medicine Berlin, Berlin, Germany
    J Neuroinflammation 9:14. 2012
    ..However, little is known so far about the clinical impact of AQP4-Ab seropositivity...
  3. doi request reprint A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    J Neurol Sci 307:164-5. 2011
    ..PRS is a very rare defect and therefore a causal relation with MIX seems possible...
  4. pmc Immunomodulation and postpartum relapses in patients with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Ther Adv Neurol Disord 2:7-11. 2009
    ..013). The results suggest that IVIG could be an option to prevent postpartum relapse of MS...
  5. doi request reprint Parenthood and immunomodulation in patients with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    J Neurol 257:580-3. 2010
    ..Despite the small numbers, our available data suggest safe paternity by MS-patients. IFN beta-treatment of mothers does not seem to have an impact on birth weight, however, MS may contribute to a reduced birth weight...
  6. doi request reprint Allergic and nonallergic delayed infusion reactions during natalizumab therapy
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Arch Neurol 65:656-8. 2008
    ..Delayed infusion reactions resembling serum sickness-type reactions (type III reaction) are commonly reported in other monoclonal antibody therapies (eg, infliximab and rituximab), but are not described yet for natalizumab...
  7. pmc Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients
    Stefanie Dahlhaus
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    J Neurol Neurosurg Psychiatry 84:1068-74. 2013
    ..We evaluated retrospectively 15 patients with natalizumab-associated PML treated at our centre...
  8. doi request reprint Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy
    Ilya Ayzenberg
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    JAMA Neurol 70:394-7. 2013
    ..To report first experiences with interleukin 6 receptor inhibition in therapy-resistant neuromyelitis optica (NMO)...
  9. pmc Benefit of repetitive intrathecal triamcinolone acetonide therapy in predominantly spinal multiple sclerosis: prediction by upper spinal cord atrophy
    Carsten Lukas
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, St Josef Hospital, Ruhr University of Bochum, Bochum, Germany
    Ther Adv Neurol Disord 2:42-9. 2009
    ..Absence of USC atrophy as measured on MRI is a predictive marker for intrathecal TCA therapy outcome in progressive MS. Patients with initial poor walking abilities, but only little or no atrophy, benefited most from TCA therapy...
  10. doi request reprint Successful management of natalizumab-associated progressive multifocal leukoencephalopathy and immune reconstitution syndrome in a patient with multiple sclerosis
    Alexandra Schröder
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Arch Neurol 67:1391-4. 2010
    ..To describe a case of successful clinical management of natalizumab-associated progressive multifocal leukoencephalopathy (PML) and immune reconstitution syndrome (IRIS) in a patient with multiple sclerosis...
  11. doi request reprint Increase in relapse rate during assisted reproduction technique in patients with multiple sclerosis
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Eur Neurol 61:65-8. 2009
    ..These results suggest that female MS patients who wish to have children should be informed that the RR may be increasing if ART is necessary...
  12. doi request reprint Failure of natalizumab to prevent relapses in neuromyelitis optica
    Ingo Kleiter
    Department of Neurology, University Medical Center Regensburg, Regensburg, Germany
    Arch Neurol 69:239-45. 2012
    ..To describe first experiences with the integrin inhibitor natalizumab, given to patients with suspected relapsing-remitting multiple sclerosis (MS) who were later diagnosed with aquaporin 4-positive neuromyelitis optica (NMO)...
  13. doi request reprint Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study
    Aiden Haghikia
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Neurology 79:2166-70. 2012
    ..MiRNAs are also present in biological fluids and may be of use as disease biomarkers. We evaluated whether miRNAs are differentially regulated in the CSF of patients with multiple sclerosis (MS)...
  14. pmc Multiple sclerosis and pregnancy: experience from a nationwide database in Germany
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Ther Adv Neurol Disord 5:247-53. 2012
    ....
  15. doi request reprint Spinal cord atrophy in spinocerebellar ataxia type 3 and 6 : impact on clinical disability
    Carsten Lukas
    Dept of Diagnostic and Interventional Radiology and Nuclear Medicine, St Josef Hospital Ruhr University Bochum, Gudrunstr 56, 44791, Bochum, Germany
    J Neurol 255:1244-9. 2008
    ..To quantify spinal cord atrophy and its impact on clinical disability in spinocerebellar ataxia (SCA) type 3 and 6...
  16. doi request reprint Pregnancy and natalizumab: results of an observational study in 35 accidental pregnancies during natalizumab treatment
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Mult Scler 17:958-63. 2011
    ..Our aim was to analyse the safety and impact of natalizumab exposure on course of disease and pregnancy outcome...
  17. pmc Ventricular tachycardia during basilar-type migraine attack
    Kalliopi Pitarokoili
    Department of Neurology, Ruhr University, St Josef Hospital, Bochum, Germany
    Ther Adv Neurol Disord 6:35-40. 2013
    ..The therapeutic implications of such a co-occurrence as well as a possible relationship between ventricular tachycardia and the underlying biology of basilar-type migraine are discussed...
  18. ncbi request reprint Efficacy of mitoxantrone and intrathecal triamcinolone acetonide treatment in chronic progressive multiple sclerosis patients
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Clin Neuropharmacol 29:286-91. 2006
    ..Future trials will show the efficacy of combination of both treatment approaches in chronic progressive patients with MS...
  19. doi request reprint Progressive multifocal leukoencephalopathy and natalizumab
    Kerstin Hellwig
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    J Neurol 258:1920-8. 2011
    ..There is a need for development of surrogate markers that would help to better define the risk of PML in individual patients...
  20. pmc Efficacy of repeated intrathecal triamcinolone acetonide application in progressive multiple sclerosis patients with spinal symptoms
    Kerstin Hellwig
    Department of Neurology, St, Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    BMC Neurol 4:18. 2004
    ..There are controversial results on the efficacy of the abandoned, intrathecal predominant methylprednisolone application in multiple sclerosis (MS) in contrast to the proven effectiveness in intractable postherpetic neuralgia...