Research Topics
Species | Kerstin HellwigSummaryAffiliation: Ruhr-University Bochum Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patientsSven Jarius
Neurocure, Charite University Medicine Berlin, Berlin, Germany
J Neuroinflammation 9:14. 2012..However, little is known so far about the clinical impact of AQP4-Ab seropositivity...
A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosisKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
J Neurol Sci 307:164-5. 2011..PRS is a very rare defect and therefore a causal relation with MIX seems possible...
Immunomodulation and postpartum relapses in patients with multiple sclerosisKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
Ther Adv Neurol Disord 2:7-11. 2009..013). The results suggest that IVIG could be an option to prevent postpartum relapse of MS...
Parenthood and immunomodulation in patients with multiple sclerosisKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
J Neurol 257:580-3. 2010..Despite the small numbers, our available data suggest safe paternity by MS-patients. IFN beta-treatment of mothers does not seem to have an impact on birth weight, however, MS may contribute to a reduced birth weight...
Allergic and nonallergic delayed infusion reactions during natalizumab therapyKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
Arch Neurol 65:656-8. 2008..Delayed infusion reactions resembling serum sickness-type reactions (type III reaction) are commonly reported in other monoclonal antibody therapies (eg, infliximab and rituximab), but are not described yet for natalizumab...
Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapyIlya Ayzenberg
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
JAMA Neurol 70:394-7. 2013..To report first experiences with interleukin 6 receptor inhibition in therapy-resistant neuromyelitis optica (NMO)...
Benefit of repetitive intrathecal triamcinolone acetonide therapy in predominantly spinal multiple sclerosis: prediction by upper spinal cord atrophyCarsten Lukas
Department of Diagnostic and Interventional Radiology and Nuclear Medicine, St Josef Hospital, Ruhr University of Bochum, Bochum, Germany
Ther Adv Neurol Disord 2:42-9. 2009..Absence of USC atrophy as measured on MRI is a predictive marker for intrathecal TCA therapy outcome in progressive MS. Patients with initial poor walking abilities, but only little or no atrophy, benefited most from TCA therapy...
Successful management of natalizumab-associated progressive multifocal leukoencephalopathy and immune reconstitution syndrome in a patient with multiple sclerosisAlexandra Schröder
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
Arch Neurol 67:1391-4. 2010..To describe a case of successful clinical management of natalizumab-associated progressive multifocal leukoencephalopathy (PML) and immune reconstitution syndrome (IRIS) in a patient with multiple sclerosis...
Increase in relapse rate during assisted reproduction technique in patients with multiple sclerosisKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
Eur Neurol 61:65-8. 2009..These results suggest that female MS patients who wish to have children should be informed that the RR may be increasing if ART is necessary...
Failure of natalizumab to prevent relapses in neuromyelitis opticaIngo Kleiter
Department of Neurology, University Medical Center Regensburg, Regensburg, Germany
Arch Neurol 69:239-45. 2012..To describe first experiences with the integrin inhibitor natalizumab, given to patients with suspected relapsing-remitting multiple sclerosis (MS) who were later diagnosed with aquaporin 4-positive neuromyelitis optica (NMO)...
Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control studyAiden Haghikia
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
Neurology 79:2166-70. 2012..MiRNAs are also present in biological fluids and may be of use as disease biomarkers. We evaluated whether miRNAs are differentially regulated in the CSF of patients with multiple sclerosis (MS)...
Multiple sclerosis and pregnancy: experience from a nationwide database in GermanyKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
Ther Adv Neurol Disord 5:247-53. 2012....
Spinal cord atrophy in spinocerebellar ataxia type 3 and 6 : impact on clinical disabilityCarsten Lukas
Dept of Diagnostic and Interventional Radiology and Nuclear Medicine, St Josef Hospital Ruhr University Bochum, Gudrunstr 56, 44791, Bochum, Germany
J Neurol 255:1244-9. 2008..To quantify spinal cord atrophy and its impact on clinical disability in spinocerebellar ataxia (SCA) type 3 and 6...
Pregnancy and natalizumab: results of an observational study in 35 accidental pregnancies during natalizumab treatmentKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
Mult Scler 17:958-63. 2011..Our aim was to analyse the safety and impact of natalizumab exposure on course of disease and pregnancy outcome...
Ventricular tachycardia during basilar-type migraine attackKalliopi Pitarokoili
Department of Neurology, Ruhr University, St Josef Hospital, Bochum, Germany
Ther Adv Neurol Disord 6:35-40. 2013..The therapeutic implications of such a co-occurrence as well as a possible relationship between ventricular tachycardia and the underlying biology of basilar-type migraine are discussed...
Efficacy of mitoxantrone and intrathecal triamcinolone acetonide treatment in chronic progressive multiple sclerosis patientsKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
Clin Neuropharmacol 29:286-91. 2006..Future trials will show the efficacy of combination of both treatment approaches in chronic progressive patients with MS...
Progressive multifocal leukoencephalopathy and natalizumabKerstin Hellwig
Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
J Neurol 258:1920-8. 2011..There is a need for development of surrogate markers that would help to better define the risk of PML in individual patients...
Efficacy of repeated intrathecal triamcinolone acetonide application in progressive multiple sclerosis patients with spinal symptomsKerstin Hellwig
Department of Neurology, St, Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
BMC Neurol 4:18. 2004..There are controversial results on the efficacy of the abandoned, intrathecal predominant methylprednisolone application in multiple sclerosis (MS) in contrast to the proven effectiveness in intractable postherpetic neuralgia...
