Beemelmanns A, Poirier M, Bayer T, Kuenzel S, Roth O. Microbial embryonal colonization during pipefish male pregnancy. Sci Rep. 2019;9:3 pubmed publisher
..The activation of the immune system induced the expansion of microbiota richness during late pregnancy, which corresponds to the time point of larval mouth opening, when initial microbial colonization must take place. ..
Roth O, Beemelmanns A, Barribeau S, Sadd B. Recent advances in vertebrate and invertebrate transgenerational immunity in the light of ecology and evolution. Heredity (Edinb). 2018;: pubmed publisher
Roth O, Keller I, Landis S, Salzburger W, Reusch T. Hosts are ahead in a marine host-parasite coevolutionary arms race: innate immune system adaptation in pipefish Syngnathus typhle against Vibrio phylotypes. Evolution. 2012;66:2528-39 pubmed publisher
..This suggests that host defense is genetically adapted against local bacteria with a broad and unspecialized host spectrum, a situation that is typical for marine systems with weak host population structure...
Roth O, Klein V, Beemelmanns A, Scharsack J, Reusch T. Male pregnancy and biparental immune priming. Am Nat. 2012;180:802-14 pubmed publisher
..Our study shows that sex role reversal in connection with male pregnancy opens the door for biparental influences on offspring immunity and may represent an additional advantage for the evolution of male pregnancy. ..
Beemelmanns A, Roth O. Biparental immune priming in the pipefish Syngnathus typhle. Zoology (Jena). 2016;119:262-72 pubmed publisher
..We could not detect an additive adaptive biparental TGIP impact. However, biparental TGIP harbours additive costs as shown in delayed sexual maturity. Epigenetic regulation may play a role both in maternal and paternal TGIP. ..
Keller I, Salzburger W, Roth O. Parental investment matters for maternal and offspring immune defense in the mouthbrooding cichlid Astatotilapia burtoni. BMC Evol Biol. 2017;17:264 pubmed publisher
..If applied simultaneously, not only mothers seem to be impacted in their performance, but also offspring are impeded in their ability to react upon a potentially virulent pathogen exposure. ..
Wendling C, Piecyk A, Refardt D, Chibani C, Hertel R, Liesegang H, et al
. Tripartite species interaction: eukaryotic hosts suffer more from phage susceptible than from phage resistant bacteria. BMC Evol Biol. 2017;17:98 pubmed publisher
Beemelmanns A, Roth O. Grandparental immune priming in the pipefish Syngnathus typhle. BMC Evol Biol. 2017;17:44 pubmed publisher
..While the benefits and costs of grandparental TGIP depend on the temporal heterogeneity of environmental conditions, multigenerational TGIP may affect host-parasite coevolution by dampening the amplitude of Red Queen Dynamics. ..