Research Topics
| Peter RohdewaldSummaryCountry: Germany Publications
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Detail Information
Publications
A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacologyP Rohdewald
Institute Pharmaceutical Chemistry, Westfalische Wilhelms Universitat Munster, Germany
Int J Clin Pharmacol Ther 40:158-68. 2002..This is a review of studies with both PYC and components of the preparation, that have helped to elucidate target sites and possible mechanisms for activity in men...
In vitro inhibition of Helicobacter pylori growth and adherence to gastric mucosal cells by PycnogenolPeter Rohdewald
Institute for Pharmaceutical Chemistry, Westfalische Wilhelms Universitat Munster, D 48161 Münster, Germany
Phytother Res 22:685-8. 2008..The results show a significant, yet limited inhibition of growth and adherence of H. pylori to gastric cells by Pycnogenol. In vivo studies have to demonstrate the clinical relevance of these findings...
Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profileSridevi Devaraj
Laboratory for Atherosclerosis and Metabolic Research, University of California, Davis, Medical Center, Sacramento, California 95817, USA
Lipids 37:931-4. 2002..Hence, following oral supplementation in humans, PYC significantly increases antioxidant capacity of plasma, as determined by ORAC, and exerts favorable effects on the lipid profile...
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patientsXiming Liu
Guang An Men Hospital of Chinese Medical Science Research Institute, Beijing, PR China
Life Sci 74:855-62. 2004..Differences in rate of side effects were not statistically significant between the two groups. Study results support a supplementation with Pycnogenol for mildly hypertensive patients...
Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type IIXiming Liu
Guang An Men Hospital of Chinese Medical Science Research Institute, Beijing, PR China
Life Sci 75:2505-13. 2004..Mild and transient unwanted effects were reported for both groups without significant differences. Supplementation of Pycnogenol to conventional diabetes treatment lowers glucose levels and improves endothelial function...
A randomised, double-blind, placebo-controlled trial on the effect of Pycnogenol on the climacteric syndrome in peri-menopausal womenHan Ming Yang
Department of Obstetrics and Gynecology, Ham Ming Hospital, Taiwan
Acta Obstet Gynecol Scand 86:978-85. 2007..French maritime pine bark extract (Pycnogenol) was found to alleviate menstrual pain and reduce hyperactivity in clinical studies. These results suggest the possibility to observe positive effects in treating climacteric syndrome...
Urinary catecholamines in children with attention deficit hyperactivity disorder (ADHD): modulation by a polyphenolic extract from pine bark (pycnogenol)Monika Dvoráková
Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic
Nutr Neurosci 10:151-7. 2007..Treatment of ADHD children with Pyc normalized catecholamine concentrations, leading to less hyperactivity, and, consequently, to reduced oxidative stress...
Treatment of ADHD with French maritime pine bark extract, PycnogenolJana Trebatická
Dept of Child Psychiatry, Child University Hospital, Faculty of Medicine, Comenius University, Limbova 1, 833 40 Bratislava, Slovakia
Eur Child Adolesc Psychiatry 15:329-35. 2006..One month after termination of Pycnogenol administration a relapse of symptoms was noted. Our results point to an option to use Pycnogenol as a natural supplement to relieve ADHD symptoms of children...
Pycnogenol as an adjunct in the management of childhood asthmaBenjamin H S Lau
Division of Microbiology and Molecular Genetics, Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA
J Asthma 41:825-32. 2004..There was also a significant reduction of urinary leukotrienes in the Pycnogenol group. The results of this study demonstrate the efficacy of Pycnogenol as an adjunct in the management of mild-to-moderate childhood asthma...
French maritime pine bark extract Pycnogenol dose-dependently lowers glucose in type 2 diabetic patientsXiming Liu
Diabetes Care 27:839. 2004
Pycnogenol in cigarette filters scavenges free radicals and reduces mutagenicity and toxicity of tobacco smoke in vivoDeliang Zhang
Institute of Biophysics, Academia Sinica, 15 Datun Road, Chaoyang District, Beijing 100101, PR China
Toxicol Ind Health 18:215-24. 2002..4 mg Pycnogenol in filters. Chronic exposure to cigarette smoke for 75 days revealed that Pycnogenol filters significantly reduced mutagenicity by up to 48% and decreased pathological changes in lung tissue...
Effect of pine bark extract (Pycnogenol) on symptoms of knee osteoarthritisPeter Cisár
2nd Department of Orthopaedics of the Comenius University School of Medicine, University Hospital Ruzinov, Ruzinovska 6, 82606 Bratislava, Slovakia
Phytother Res 22:1087-92. 2008..The aim of the study was to evaluate whether Pycnogenol reduces the symptoms of OA in a double-blind, placebo-controlled, randomly allocated trial with patients suffering from knee osteoarthritis stages I and II...
