Ole Wichmann

Summary

Affiliation: Robert Koch-Institut
Country: Germany

Publications

  1. ncbi request reprint [Effectiveness, population-level effects, and heath economics of measles and rubella vaccination]
    O Wichmann
    Fachgebiet Impfprävention, Abteilung für Infektionsepidemiologie, Robert Koch Institut, Seestr 10, 13353, Berlin, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:1260-9. 2013
  2. pmc Dengue in Thailand and Cambodia: an assessment of the degree of underrecognized disease burden based on reported cases
    Ole Wichmann
    Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Seoul, Korea
    PLoS Negl Trop Dis 5:e996. 2011
  3. ncbi request reprint Large measles outbreak at a German public school, 2006
    Ole Wichmann
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Pediatr Infect Dis J 26:782-6. 2007
  4. ncbi request reprint High residual chloroquine blood levels in African children with severe malaria seeking healthcare
    Ole Wichmann
    Institute of Tropical Medicine and International Health, Charite University Medicine, Berlin, Germany
    Trans R Soc Trop Med Hyg 101:637-42. 2007
  5. ncbi request reprint Severe dengue virus infection in travelers: risk factors and laboratory indicators
    Ole Wichmann
    Institute of Tropical Medicine, Charite University Medicine, Berlin, Germany
    J Infect Dis 195:1089-96. 2007
  6. pmc Clinical features and pitfalls in the laboratory diagnosis of dengue in travellers
    Ole Wichmann
    Berlin Institute of Tropical Medicine, Spandauer Damm 130, 14050 Berlin, Germany
    BMC Infect Dis 6:120. 2006
  7. ncbi request reprint Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe
    Ole Wichmann
    Institute of Tropical Medicine, Charite, Humboldt University, Berlin, Germany
    J Infect Dis 190:1541-6. 2004
  8. pmc Dengue antibody prevalence in German travelers
    Ole Wichmann
    Berlin Institute of Tropical Medicine, Berlin, Germany
    Emerg Infect Dis 11:762-5. 2005
  9. pmc Prospective hospital-based case-control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009-2010 using matched hospital and test-negative controls
    Wiebke Hellenbrand
    Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:127. 2012
  10. pmc Further efforts needed to achieve measles elimination in Germany: results of an outbreak investigation
    Ole Wichmann
    Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Bull World Health Organ 87:108-15. 2009

Detail Information

Publications40

  1. ncbi request reprint [Effectiveness, population-level effects, and heath economics of measles and rubella vaccination]
    O Wichmann
    Fachgebiet Impfprävention, Abteilung für Infektionsepidemiologie, Robert Koch Institut, Seestr 10, 13353, Berlin, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:1260-9. 2013
    ..In Germany, catch-up vaccination programs are urgently needed for children, adolescents, and young adults specifically in the western federal states. ..
  2. pmc Dengue in Thailand and Cambodia: an assessment of the degree of underrecognized disease burden based on reported cases
    Ole Wichmann
    Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Seoul, Korea
    PLoS Negl Trop Dis 5:e996. 2011
    ....
  3. ncbi request reprint Large measles outbreak at a German public school, 2006
    Ole Wichmann
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Pediatr Infect Dis J 26:782-6. 2007
    ..An investigation was launched to determine reasons for the resurgence of measles, assess vaccination coverage and vaccine effectiveness (VE)...
  4. ncbi request reprint High residual chloroquine blood levels in African children with severe malaria seeking healthcare
    Ole Wichmann
    Institute of Tropical Medicine and International Health, Charite University Medicine, Berlin, Germany
    Trans R Soc Trop Med Hyg 101:637-42. 2007
    ..In areas of intense chloroquine resistance and frequent pre-treatment, additional administration of chloroquine at hospital admission is not only ineffective but may even further endanger patients...
  5. ncbi request reprint Severe dengue virus infection in travelers: risk factors and laboratory indicators
    Ole Wichmann
    Institute of Tropical Medicine, Charite University Medicine, Berlin, Germany
    J Infect Dis 195:1089-96. 2007
    ..Data on severity and secondary infection rates in a population of travelers are lacking...
  6. pmc Clinical features and pitfalls in the laboratory diagnosis of dengue in travellers
    Ole Wichmann
    Berlin Institute of Tropical Medicine, Spandauer Damm 130, 14050 Berlin, Germany
    BMC Infect Dis 6:120. 2006
    ..In practice, however, often only one blood sample is available from febrile travellers returning from dengue endemic areas...
  7. ncbi request reprint Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe
    Ole Wichmann
    Institute of Tropical Medicine, Charite, Humboldt University, Berlin, Germany
    J Infect Dis 190:1541-6. 2004
    ..However, little is known about the prevalence of codon-268 mutations and their quantitative association with treatment failure...
  8. pmc Dengue antibody prevalence in German travelers
    Ole Wichmann
    Berlin Institute of Tropical Medicine, Berlin, Germany
    Emerg Infect Dis 11:762-5. 2005
    ..Serotype-specific dengue antibodies indicated acute infections in 51 (4.7%) travelers with recent fever and 13 (1.1%) travelers with no recent fever, depending largely on destination and epidemic activity in the countries visited...
  9. pmc Prospective hospital-based case-control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009-2010 using matched hospital and test-negative controls
    Wiebke Hellenbrand
    Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:127. 2012
    ....
  10. pmc Further efforts needed to achieve measles elimination in Germany: results of an outbreak investigation
    Ole Wichmann
    Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Bull World Health Organ 87:108-15. 2009
    ..To determine morbidity and costs related to a large measles outbreak in Germany and to identify ways to improve the country's national measles elimination strategy...
  11. doi request reprint Determinants of tetanus and seasonal influenza vaccine uptake in adults living in Germany
    Merle M Böhmer
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    Hum Vaccin 7:1317-25. 2011
    ..For tetanus, information activities should target population groups with an increased risk of being undervaccinated...
  12. doi request reprint Seasonal influenza vaccine uptake in Germany 2007/2008 and 2008/2009: results from a national health update survey
    Merle M Böhmer
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    Vaccine 29:4492-8. 2011
    ..4% in 2008/2009) vaccinated than the general population (30.8% and 28.1%). Special effort must be undertaken to develop immunization strategies for improved vaccine uptake in target groups, especially in healthcare workers...
  13. doi request reprint Determinants of malaria prophylaxis among German travelers to Kenya, Senegal, and Thailand
    Gwendolin Ropers
    Department of Infectious Disease Epidemiology, Robert Koch Institut, Berlin, Germany
    J Travel Med 15:162-71. 2008
    ..This study assessed the determinants for seeking pretravel advice and evaluated the quality of advice from each source and its influence on the patterns and outcome of malaria prophylaxis intake...
  14. pmc Barriers to pandemic influenza vaccination and uptake of seasonal influenza vaccine in the post-pandemic season in Germany
    Merle M Böhmer
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    BMC Public Health 12:938. 2012
    ....
  15. doi request reprint Closer to the goal: efforts in measles elimination in Germany 2010
    Anette Siedler
    Department for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Berlin, Germany
    J Infect Dis 204:S373-80. 2011
    ..Intensification of public awareness and sound information on vaccinations are necessary to convince skeptics and remind the forgetful...
  16. pmc Malarone treatment failure not associated with previously described mutations in the cytochrome b gene
    Ole Wichmann
    Institute of Tropical Medicine, Charite, Humboldt University, Berlin, Germany
    Malar J 3:14. 2004
    ..These findings illustrate the spread of atovaquone-proguanil-resistance in Africa and question the usefulness of codon 268 as the only target for the surveillance of its emergence...
  17. ncbi request reprint Epidemiology and cost of herpes zoster and postherpetic neuralgia in Germany
    Bernhard Ultsch
    Immunisation Unit, Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086, Berlin, Germany
    Eur J Health Econ 14:1015-26. 2013
    ..HZ and PHN place a considerable burden on the German SHI-system. Since HZ-vaccines will soon be available, a health-economic evaluation of these vaccines should be conducted...
  18. pmc Impact of rotavirus vaccination in regions with low and moderate vaccine uptake in Germany
    Sandra Dudareva-Vizule
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    Hum Vaccin Immunother 8:1407-15. 2012
    ..In conclusion, in the German setting with low to moderate vaccine uptake, RV-related hospitalization incidence decreased substantially depending on the achieved vaccination coverage, but only in the first two years of life...
  19. pmc Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenza
    Matthias Nachtnebel
    Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin 13086, Germany
    BMC Public Health 12:245. 2012
    ..12.2009 to 12.12.2010 according to different case definitions (CD) and determined the proportion of cases with influenza A(H1N1)pdm09 (pH1N1). We compared the sensitivity and specificity of CD for capturing pandemic pH1N1 cases...
  20. pmc Communicable diseases prioritized for surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011
    Yanina Balabanova
    Robert Koch Institute, Berlin, Germany
    PLoS ONE 6:e25691. 2011
    ....
  21. pmc Molecular surveillance of the antifolate-resistant mutation I164L in imported African isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop
    Ole Wichmann
    Institute of Tropical Medicine, Charite, Humboldt University, Berlin, Germany
    Malar J 2:17. 2003
    ..The objective of this study was to assess the prevalence of this mutation in African isolates of Plasmodium falciparum that have been imported into Europe through travellers...
  22. pmc Health economic evaluation of vaccination strategies for the prevention of herpes zoster and postherpetic neuralgia in Germany
    Bernhard Ultsch
    Immunisation Unit, Robert Koch Institute, Berlin, Germany
    BMC Health Serv Res 13:359. 2013
    ..To support an informed decision-making for a potential vaccination recommendation, we conducted a health economic evaluation to identify the most cost-effective vaccination strategy...
  23. doi request reprint Rotavirus vaccine effectiveness and case-control study on risk factors for breakthrough infections in Germany, 2010-2011
    Cornelia Adlhoch
    Postgraduate Training for Applied Epidemiology, Robert Koch Institute, Berlin, Germany
    Pediatr Infect Dis J 32:e82-9. 2013
    ..The effectiveness of RV vaccination was investigated after an unexpectedly high number of RV infections in fully vaccinated children occurred...
  24. pmc Herpes zoster in Germany: quantifying the burden of disease
    Bernhard Ultsch
    Immunization Unit, Robert Koch Institute, 13086 Berlin, Germany
    BMC Infect Dis 11:173. 2011
    ..To support the decision making process related to a potential vaccination recommendation, we estimated annual HZ disease burden in people aged≥50 years in Germany by utilizing various data sources...
  25. doi request reprint Molecular and serologic markers of acute dengue infection in naive and flavivirus-vaccinated travelers
    Cristina Domingo
    Diagnostic Microbiology Service, National Center for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain
    Diagn Microbiol Infect Dis 65:42-8. 2009
    ..6% of yellow fever vaccinated patients. The proper use of these simple methodologies could help in the identification of patients affected with secondary infection, who may be at a higher risk of developing a hemorrhagic disorder...
  26. doi request reprint Molecular surveillance of circulating dengue genotypes through European travelers
    Cristina Domingo
    Diagnostic Microbiology, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
    J Travel Med 18:183-90. 2011
    ..In this context, surveillance and identification of the appearance or introduction of more virulent strains, along with fluctuation of DENV among endemic areas are now considered essential public health activities...
  27. pmc Evidence-based decision-making in infectious diseases epidemiology, prevention and control: matching research questions to study designs and quality appraisal tools
    Thomas Harder
    Robert Koch Institute, Berlin, Germany
    BMC Med Res Methodol 14:69. 2014
    ..One of the first steps was to review existing quality appraisal tools (QATs) for individual research studies of various designs relevant to this area, using a question-based approach...
  28. pmc Human Papillomavirus prevalence and probable first effects of vaccination in 20 to 25 year-old women in Germany: a population-based cross-sectional study via home-based self-sampling
    Yvonne Déleré
    Immunisation Unit, Department for Infectious Disease Epidemiology, Robert Koch Institute, Seestraße 10 13353 Berlin, Germany
    BMC Infect Dis 14:87. 2014
    ..Estimates of Human Papillomavirus (HPV) prevalence in a population prior to and after HPV vaccine introduction are essential to evaluate the short-term impact of vaccination...
  29. doi request reprint Epidemiology of invasive meningococcal disease in Germany, 2002-2010, and impact of vaccination with meningococcal C conjugate vaccine
    Wiebke Hellenbrand
    Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    J Infect 66:48-56. 2013
    ....
  30. ncbi request reprint Dengue in travelers: a review
    Ole Wichmann
    Institute of Tropical Medicine, Humboldt University, Berlin, Germany
    J Travel Med 11:161-70. 2004
  31. ncbi request reprint Risk and spectrum of diseases in travelers to popular tourist destinations
    Julia Rack
    Berlin Institute of Tropical Medicine, Berlin, Germany
    J Travel Med 12:248-53. 2005
    ..The objective of this study was to elucidate the risk for travel-related diseases, symptoms, and accidents in a population of Europeans who travel to popular tourist destinations...
  32. doi request reprint Seroprevalence study of Francisella tularensis among hunters in Germany
    Andrea Jenzora
    Centre for Biological Safety, Robert Koch Institut, Berlin, Germany
    FEMS Immunol Med Microbiol 53:183-9. 2008
    ..tularensis compared with the cross-sectional study (OR=7.7; P<0.001). This indicates a higher prevalence for tularemia in hunters of a suspected endemic region of Germany...
  33. doi request reprint Phylogenetic and case-control study on hepatitis E virus infection in Germany
    Ole Wichmann
    Department of Infectious Disease Epidemiology, Robert Koch Institute, Germany
    J Infect Dis 198:1732-41. 2008
    ..The number of non-travel-associated infections has increased in recent years, but the route of transmission in most is unknown. Our objective was to determine risk factors for autochthonous HEV infections in Germany...
  34. doi request reprint Monitoring pandemic influenza A(H1N1) vaccination coverage in Germany 2009/10 - results from thirteen consecutive cross-sectional surveys
    Dietmar Walter
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Vaccine 29:4008-12. 2011
    ..8; 95%CI: 7.2-10.8). The campaign failed to reach people at risk who were not used to receive their annual seasonal influenza shot...
  35. pmc The first wave of pandemic influenza (H1N1) 2009 in Germany: from initiation to acceleration
    Gabriele Poggensee
    Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 10:155. 2010
    ..However, the first wave with measurable burden of disease started only in October 2009. The basic epidemiological and clinical characteristics of the pandemic were analysed in order to understand the course of the pandemic in Germany...
  36. ncbi request reprint Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in Chonburi, Thailand
    Ole Wichmann
    Institute of Tropical Medicine, Humboldt University, Berlin, Germany
    Trop Med Int Health 9:1022-9. 2004
    ..In recent years, there has been a progressive shift in age-distribution towards older children and adults. We investigated an outbreak in 2001 in both children and adults, in an endemic area of Thailand...
  37. doi request reprint Methodological quality of systematic reviews on influenza vaccination
    Cornelius Remschmidt
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    Vaccine 32:1678-84. 2014
    ..Systematic reviews are of particular importance for policy decisions. However, their methodological quality can vary considerably...
  38. ncbi request reprint Risk factors for cervical human papillomavirus infection and high-grade intraepithelial lesion in women aged 20 to 31 years in Germany
    Cornelius Remschmidt
    Immunization Unit, Robert Koch Institute, Berlin, Germany
    Int J Gynecol Cancer 23:519-26. 2013
    ..Therefore, we conducted a study to identify epidemiological risk factors for the following: (1) the presence of HPV among women without a recent diagnosis of HSIL and (2) HSIL...
  39. pmc Health economics of dengue: a systematic literature review and expert panel's assessment
    Mark E Beatty
    Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Kwanak gu, Seoul, Republic of Korea
    Am J Trop Med Hyg 84:473-88. 2011
    ..Health economic research specific to dengue is urgently needed to ensure informed decision making on the various options for controlling and preventing this disease...
  40. pmc Molecular surveillance of drug resistance through imported isolates of Plasmodium falciparum in Europe
    Tomas Jelinek
    Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstr, 5, 80802 Munich, Germany
    Malar J 1:11. 2002
    ..The screening results were used to map the prevalence of mutations and, thus, levels of potential drug resistance in endemic areas world-wide...