Affiliation: Robert Koch-Institut
- [Detection of local influenza outbreaks and role of virological diagnostics]B Schweiger
Fachgebiet Influenza und respiratorische Infektionen, Robert Koch Institut, Nordufer 20, 13353, Berlin, Deutschland
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:28-37. 2013....
- Comparison of the novel ResPlex III assay and existing techniques for the detection and subtyping of influenza virus during the influenza season 2006-2007M Eggers
Laboratory Prof G Enders and Partner and Institute of Virology, Infectious Diseases and Epidemiology e V, Rosenbergstrasse 85, 70193, Stuttgart, Germany
Eur J Clin Microbiol Infect Dis 31:1257-65. 2012....
- Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenzaMatthias Nachtnebel
Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin 13086, Germany
BMC Public Health 12:245. 2012..12.2009 to 12.12.2010 according to different case definitions (CD) and determined the proportion of cases with influenza A(H1N1)pdm09 (pH1N1). We compared the sensitivity and specificity of CD for capturing pandemic pH1N1 cases...
- The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011Thorsten Suess
Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
BMC Infect Dis 12:26. 2012..We aimed to investigate efficacy, acceptability, and tolerability of NPI in households with influenza index patients...
- Avian influenza virus risk assessment in falconryAndrea Kohls
Free University of Berlin, Faculty of Veterinary Medicine, Institute of Poultry Diseases, Berlin, Germany
Virol J 8:187. 2011..Both (hunting birds and prey birds) seem to be highly susceptible to some AIV strains, especially H5N1. We therefore conducted a field study to investigate AIV infections in falconers, their falconry birds as well as prey birds...
- Protective measures and H5N1-seroprevalence among personnel tasked with bird collection during an outbreak of avian influenza A/H5N1 in wild birds, Ruegen, Germany, 2006Wei Cai
Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin, Germany
BMC Infect Dis 9:170. 2009..The aim of this study was to investigate the use of recommended protective measures and to measure H5N1-seroprevalence among personnel tasked with bird collection...
- Seasonal influenza risk in hospital healthcare workers is more strongly associated with household than occupational exposures: results from a prospective cohort study in Berlin, Germany, 2006/07Chris J Williams
Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
BMC Infect Dis 10:8. 2010..We aimed to compare the risk of influenza infection in healthcare workers in acute hospital care with that in non-healthcare workers over the same season...
- Antigenic drift and variability of influenza virusesB Schweiger
National Reference Center for Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
Med Microbiol Immunol 191:133-8. 2002..Our results suggest that molecular analysis of the HA gene is important to complement the antigenic characterization for a better selection of appropriate vaccine strains...
- Reassortment between human A(H3N2) viruses is an important evolutionary mechanismB Schweiger
National Reference Centre for Influenza, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
Vaccine 24:6683-90. 2006....
- [Molecular characterization of human influenza viruses--a look back on the last 10 years]Brunhilde Schweiger
Nationales Referenzzentrum für Influenza, FG Virale Infektionen, Robert Koch Institut, Berlin
Berl Munch Tierarztl Wochenschr 119:167-78. 2006..Reassortant B viruses possessing a Victoria/87-lineage HA and a Yamagata/88-like NA were predominant in Germany during 2002/03 and 2004/05...
- Genetic variability of group A human respiratory syncytial virus strains circulating in Germany from 1998 to 2007Janine Reiche
FG12 Virale Infektionen, NRZ Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
J Clin Microbiol 47:1800-10. 2009..This study provides for the first time data on the circulation pattern of RSV group A genotypes and their molecular characterization in Germany during nine consecutive epidemic seasons...
- SARS coronavirus detectionAndreas Nitsche
Robert Koch Institut, Berlin, Germany
Emerg Infect Dis 10:1300-3. 2004..The assays consider all currently available SARS-CoV sequences and are optimized for two prominent real-time PCR platforms...
- Development of a PCR-based assay for detection, quantification, and genotyping of human adenovirusesBarbara Chmielewicz
Robert Koch Institut, Zentrum für Biologische Sicherheit 1, FG12 Virale Infektionen, Berlin, Germany
Clin Chem 51:1365-73. 2005..A method for virus quantification in clinical specimens is essential for monitoring patient adenoviral loads and evaluating new therapeutic approaches...
- Shedding and transmission of novel influenza virus A/H1N1 infection in households--Germany, 2009Thorsten Suess
Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
Am J Epidemiol 171:1157-64. 2010..Compared with other nasopharyngeal specimen types, nasal wash was the most sensitive. These results support the notion that epidemiologic and virologic characteristics of NIV are in many aspects similar to those of seasonal influenza...
- Human adenoviruses in respiratory infections: sequencing of the hexon hypervariable region reveals high sequence variabilityBarbara Biere
Robert Koch Institut, Nationales Referenzzentrum für Influenza, Nordufer 20, 13353 Berlin, Germany
J Clin Virol 47:366-71. 2010..The molecular typing of hAdV hexon sequences can help to speed up the discrimination of serotypes, thus improving on-time epidemiological examinations and patient care...
- Differentiation of influenza B virus lineages Yamagata and Victoria by real-time PCRBarbara Biere
Robert Koch Institut, FG17 Influenza Respiratorische Viren, Nordufer 20, 13353 Berlin, Germany
J Clin Microbiol 48:1425-7. 2010..We present the first real-time PCR assay for virus lineage differentiation to supplement classical antigenic analyses. The assay was successfully applied to 310 primary samples collected in Germany from 2007 to 2009...
- Respiratory disease caused by a species B2 adenovirus in a military camp in TurkeyBarbara Chmielewicz
Robert Koch Institut, Projektgruppe 11, HIV Variabilität und Molekulare Epidemiologie, Nordufer 20, Berlin, Germany
J Med Virol 77:232-7. 2005..The adenovirus detected was characterized further by genotyping and was identified as a species B2 virus with the highest similarity to adenovirus type 11a...
- A new and rapid genotypic assay for the detection of neuraminidase inhibitor resistant influenza A viruses of subtype H1N1, H3N2, and H5N1Susanne Duwe
National Reference Centre for Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
J Virol Methods 153:134-41. 2008..The results obtained with these controls showed that the assay can discriminate clearly the wild-type virus from a mutant virus. The detection limit of minor virus variants within the viral quasispecies amounts to 10%...
- Early detection of influenza A and B infection in infants and children using conventional and fluorescence-based rapid testingBarbara Rath
Department of Paediatrics, Division of Pneumonology Immunology, Charité University Medical Centre, Augustenburger Platz 1, Berlin, Germany
J Clin Virol 55:329-33. 2012..The appropriate management of infants and children with influenza depends on the accurate and timely diagnosis, ideally at the point of care (POC)...
- The first wave of pandemic influenza (H1N1) 2009 in Germany: from initiation to accelerationGabriele Poggensee
Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
BMC Infect Dis 10:155. 2010..However, the first wave with measurable burden of disease started only in October 2009. The basic epidemiological and clinical characteristics of the pandemic were analysed in order to understand the course of the pandemic in Germany...
- Pandemic human viruses cause decline of endangered great apesSophie Köndgen
Robert Koch Institut, Nordufer 20, D 13353 Berlin, Germany
Curr Biol 18:260-4. 2008..These observations illustrate the challenge of maximizing the benefit of research and tourism to great apes while minimizing the negative side effects...
- Global distribution of novel rhinovirus genotypeThomas Briese
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Emerg Infect Dis 14:944-7. 2008..Molecular dating indicates that these viruses have been circulating for at least 250 years...
- A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in GermanyNeil Renwick
Center for Infection and Immunity, Mailman School of Public Health, and College of Physicians and Surgeons, Columbia University, 722 W 168th Street, New York, NY 10032, USA
J Infect Dis 196:1754-60. 2007..Infections with the novel genotype were associated with upper-respiratory-tract symptoms but, more frequently, with bronchitis, bronchiolitis, and pneumonia...
- [Influenza in Germany. "Caution! Influenza--danger"]Brunhilde Schweiger
Influenza-Referenzzentrums, Robert Koch-Institut (RKI, Berlin
Krankenpfl J 41:162-3. 2003
- Fatal influenza A virus infection in a child vaccinated against influenzaPeter Thomas
Kinderklinik, Klinikum Krefeld, Robert-Koch-Institut, Germany
Pediatr Infect Dis J 22:201-2. 2003..This case indicates that a primary viral pneumonia with influenza A virus complicated by a bacterial superinfection with S. aureus can run a fatal course even in a vaccinated child...
- Programme of the Community Network of Reference Laboratories for Human Influenza to improve Influenza Surveillance in EuropeAdam Meijer
Netherlands Institute for Health Services Research NIVEL, European Influenza Surveillance Scheme Co ordination Centre, Otterstraat 118 124, 3513 Utrecht, CR, The Netherlands
Vaccine 24:6717-23. 2006....