Brunhilde Schweiger

Summary

Affiliation: Robert Koch-Institut
Country: Germany

Publications

  1. pmc Prospective hospital-based case-control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009-2010 using matched hospital and test-negative controls
    Wiebke Hellenbrand
    Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:127. 2012
  2. doi request reprint [Detection of local influenza outbreaks and role of virological diagnostics]
    B Schweiger
    Fachgebiet Influenza und respiratorische Infektionen, Robert Koch Institut, Nordufer 20, 13353, Berlin, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:28-37. 2013
  3. pmc Comparison of the novel ResPlex III assay and existing techniques for the detection and subtyping of influenza virus during the influenza season 2006-2007
    M Eggers
    Laboratory Prof G Enders and Partner and Institute of Virology, Infectious Diseases and Epidemiology e V, Rosenbergstrasse 85, 70193, Stuttgart, Germany
    Eur J Clin Microbiol Infect Dis 31:1257-65. 2012
  4. pmc Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenza
    Matthias Nachtnebel
    Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin 13086, Germany
    BMC Public Health 12:245. 2012
  5. pmc The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011
    Thorsten Suess
    Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:26. 2012
  6. pmc Avian influenza virus risk assessment in falconry
    Andrea Kohls
    Free University of Berlin, Faculty of Veterinary Medicine, Institute of Poultry Diseases, Berlin, Germany
    Virol J 8:187. 2011
  7. pmc Protective measures and H5N1-seroprevalence among personnel tasked with bird collection during an outbreak of avian influenza A/H5N1 in wild birds, Ruegen, Germany, 2006
    Wei Cai
    Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin, Germany
    BMC Infect Dis 9:170. 2009
  8. pmc Seasonal influenza risk in hospital healthcare workers is more strongly associated with household than occupational exposures: results from a prospective cohort study in Berlin, Germany, 2006/07
    Chris J Williams
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    BMC Infect Dis 10:8. 2010
  9. ncbi request reprint Antigenic drift and variability of influenza viruses
    B Schweiger
    National Reference Center for Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    Med Microbiol Immunol 191:133-8. 2002
  10. ncbi request reprint Reassortment between human A(H3N2) viruses is an important evolutionary mechanism
    B Schweiger
    National Reference Centre for Influenza, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Vaccine 24:6683-90. 2006

Collaborators

Detail Information

Publications27

  1. pmc Prospective hospital-based case-control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009-2010 using matched hospital and test-negative controls
    Wiebke Hellenbrand
    Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:127. 2012
    ....
  2. doi request reprint [Detection of local influenza outbreaks and role of virological diagnostics]
    B Schweiger
    Fachgebiet Influenza und respiratorische Infektionen, Robert Koch Institut, Nordufer 20, 13353, Berlin, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:28-37. 2013
    ....
  3. pmc Comparison of the novel ResPlex III assay and existing techniques for the detection and subtyping of influenza virus during the influenza season 2006-2007
    M Eggers
    Laboratory Prof G Enders and Partner and Institute of Virology, Infectious Diseases and Epidemiology e V, Rosenbergstrasse 85, 70193, Stuttgart, Germany
    Eur J Clin Microbiol Infect Dis 31:1257-65. 2012
    ....
  4. pmc Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenza
    Matthias Nachtnebel
    Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin 13086, Germany
    BMC Public Health 12:245. 2012
    ..12.2009 to 12.12.2010 according to different case definitions (CD) and determined the proportion of cases with influenza A(H1N1)pdm09 (pH1N1). We compared the sensitivity and specificity of CD for capturing pandemic pH1N1 cases...
  5. pmc The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011
    Thorsten Suess
    Department of Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 12:26. 2012
    ..We aimed to investigate efficacy, acceptability, and tolerability of NPI in households with influenza index patients...
  6. pmc Avian influenza virus risk assessment in falconry
    Andrea Kohls
    Free University of Berlin, Faculty of Veterinary Medicine, Institute of Poultry Diseases, Berlin, Germany
    Virol J 8:187. 2011
    ..Both (hunting birds and prey birds) seem to be highly susceptible to some AIV strains, especially H5N1. We therefore conducted a field study to investigate AIV infections in falconers, their falconry birds as well as prey birds...
  7. pmc Protective measures and H5N1-seroprevalence among personnel tasked with bird collection during an outbreak of avian influenza A/H5N1 in wild birds, Ruegen, Germany, 2006
    Wei Cai
    Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, Berlin, Germany
    BMC Infect Dis 9:170. 2009
    ..The aim of this study was to investigate the use of recommended protective measures and to measure H5N1-seroprevalence among personnel tasked with bird collection...
  8. pmc Seasonal influenza risk in hospital healthcare workers is more strongly associated with household than occupational exposures: results from a prospective cohort study in Berlin, Germany, 2006/07
    Chris J Williams
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    BMC Infect Dis 10:8. 2010
    ..We aimed to compare the risk of influenza infection in healthcare workers in acute hospital care with that in non-healthcare workers over the same season...
  9. ncbi request reprint Antigenic drift and variability of influenza viruses
    B Schweiger
    National Reference Center for Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    Med Microbiol Immunol 191:133-8. 2002
    ..Our results suggest that molecular analysis of the HA gene is important to complement the antigenic characterization for a better selection of appropriate vaccine strains...
  10. ncbi request reprint Reassortment between human A(H3N2) viruses is an important evolutionary mechanism
    B Schweiger
    National Reference Centre for Influenza, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Vaccine 24:6683-90. 2006
    ....
  11. ncbi request reprint [Molecular characterization of human influenza viruses--a look back on the last 10 years]
    Brunhilde Schweiger
    Nationales Referenzzentrum für Influenza, FG Virale Infektionen, Robert Koch Institut, Berlin
    Berl Munch Tierarztl Wochenschr 119:167-78. 2006
    ..Reassortant B viruses possessing a Victoria/87-lineage HA and a Yamagata/88-like NA were predominant in Germany during 2002/03 and 2004/05...
  12. pmc Genetic variability of group A human respiratory syncytial virus strains circulating in Germany from 1998 to 2007
    Janine Reiche
    FG12 Virale Infektionen, NRZ Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Clin Microbiol 47:1800-10. 2009
    ..This study provides for the first time data on the circulation pattern of RSV group A genotypes and their molecular characterization in Germany during nine consecutive epidemic seasons...
  13. pmc SARS coronavirus detection
    Andreas Nitsche
    Robert Koch Institut, Berlin, Germany
    Emerg Infect Dis 10:1300-3. 2004
    ..The assays consider all currently available SARS-CoV sequences and are optimized for two prominent real-time PCR platforms...
  14. ncbi request reprint Development of a PCR-based assay for detection, quantification, and genotyping of human adenoviruses
    Barbara Chmielewicz
    Robert Koch Institut, Zentrum für Biologische Sicherheit 1, FG12 Virale Infektionen, Berlin, Germany
    Clin Chem 51:1365-73. 2005
    ..A method for virus quantification in clinical specimens is essential for monitoring patient adenoviral loads and evaluating new therapeutic approaches...
  15. ncbi request reprint Respiratory disease caused by a species B2 adenovirus in a military camp in Turkey
    Barbara Chmielewicz
    Robert Koch Institut, Projektgruppe 11, HIV Variabilität und Molekulare Epidemiologie, Nordufer 20, Berlin, Germany
    J Med Virol 77:232-7. 2005
    ..The adenovirus detected was characterized further by genotyping and was identified as a species B2 virus with the highest similarity to adenovirus type 11a...
  16. doi request reprint Shedding and transmission of novel influenza virus A/H1N1 infection in households--Germany, 2009
    Thorsten Suess
    Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Am J Epidemiol 171:1157-64. 2010
    ..Compared with other nasopharyngeal specimen types, nasal wash was the most sensitive. These results support the notion that epidemiologic and virologic characteristics of NIV are in many aspects similar to those of seasonal influenza...
  17. doi request reprint Human adenoviruses in respiratory infections: sequencing of the hexon hypervariable region reveals high sequence variability
    Barbara Biere
    Robert Koch Institut, Nationales Referenzzentrum für Influenza, Nordufer 20, 13353 Berlin, Germany
    J Clin Virol 47:366-71. 2010
    ..The molecular typing of hAdV hexon sequences can help to speed up the discrimination of serotypes, thus improving on-time epidemiological examinations and patient care...
  18. pmc Differentiation of influenza B virus lineages Yamagata and Victoria by real-time PCR
    Barbara Biere
    Robert Koch Institut, FG17 Influenza Respiratorische Viren, Nordufer 20, 13353 Berlin, Germany
    J Clin Microbiol 48:1425-7. 2010
    ..We present the first real-time PCR assay for virus lineage differentiation to supplement classical antigenic analyses. The assay was successfully applied to 310 primary samples collected in Germany from 2007 to 2009...
  19. doi request reprint A new and rapid genotypic assay for the detection of neuraminidase inhibitor resistant influenza A viruses of subtype H1N1, H3N2, and H5N1
    Susanne Duwe
    National Reference Centre for Influenza, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Virol Methods 153:134-41. 2008
    ..The results obtained with these controls showed that the assay can discriminate clearly the wild-type virus from a mutant virus. The detection limit of minor virus variants within the viral quasispecies amounts to 10%...
  20. doi request reprint Early detection of influenza A and B infection in infants and children using conventional and fluorescence-based rapid testing
    Barbara Rath
    Department of Paediatrics, Division of Pneumonology Immunology, Charité University Medical Centre, Augustenburger Platz 1, Berlin, Germany
    J Clin Virol 55:329-33. 2012
    ..The appropriate management of infants and children with influenza depends on the accurate and timely diagnosis, ideally at the point of care (POC)...
  21. pmc The first wave of pandemic influenza (H1N1) 2009 in Germany: from initiation to acceleration
    Gabriele Poggensee
    Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ Ring 1, 13086 Berlin, Germany
    BMC Infect Dis 10:155. 2010
    ..However, the first wave with measurable burden of disease started only in October 2009. The basic epidemiological and clinical characteristics of the pandemic were analysed in order to understand the course of the pandemic in Germany...
  22. doi request reprint Pandemic human viruses cause decline of endangered great apes
    Sophie Köndgen
    Robert Koch Institut, Nordufer 20, D 13353 Berlin, Germany
    Curr Biol 18:260-4. 2008
    ..These observations illustrate the challenge of maximizing the benefit of research and tourism to great apes while minimizing the negative side effects...
  23. pmc Global distribution of novel rhinovirus genotype
    Thomas Briese
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 14:944-7. 2008
    ..Molecular dating indicates that these viruses have been circulating for at least 250 years...
  24. ncbi request reprint A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany
    Neil Renwick
    Center for Infection and Immunity, Mailman School of Public Health, and College of Physicians and Surgeons, Columbia University, 722 W 168th Street, New York, NY 10032, USA
    J Infect Dis 196:1754-60. 2007
    ..Infections with the novel genotype were associated with upper-respiratory-tract symptoms but, more frequently, with bronchitis, bronchiolitis, and pneumonia...
  25. ncbi request reprint [Influenza in Germany. "Caution! Influenza--danger"]
    Brunhilde Schweiger
    Influenza Referenzzentrums, Robert Koch Institut RKI, Berlin
    Krankenpfl J 41:162-3. 2003
  26. ncbi request reprint Fatal influenza A virus infection in a child vaccinated against influenza
    Peter Thomas
    Kinderklinik, Klinikum Krefeld, Robert Koch Institut, Germany
    Pediatr Infect Dis J 22:201-2. 2003
    ..This case indicates that a primary viral pneumonia with influenza A virus complicated by a bacterial superinfection with S. aureus can run a fatal course even in a vaccinated child...
  27. ncbi request reprint Programme of the Community Network of Reference Laboratories for Human Influenza to improve Influenza Surveillance in Europe
    Adam Meijer
    Netherlands Institute for Health Services Research NIVEL, European Influenza Surveillance Scheme Co ordination Centre, Otterstraat 118 124, 3513 Utrecht, CR, The Netherlands
    Vaccine 24:6717-23. 2006
    ....