Research Topics
Species | Norbert BannertSummaryAffiliation: Robert Koch-Institut Country: Germany Publications
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Detail Information
Publications
PDZ Domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunitsNorbert Bannert
Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
J Biol Chem 278:42190-9. 2003..Alternatively, an intracellular complex of npro-IL-16, ion channels, and components of myosin motors in neurons suggests a role in protein targeting...
Retroelements and the human genome: new perspectives on an old relationNorbert Bannert
Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
Proc Natl Acad Sci U S A 101:14572-9. 2004..The remarkable progress in the analysis of host genomes has brought to light the significant impact of HERVs and other retroelements on genetic variation, genome evolution, and gene regulation...
The evolutionary dynamics of human endogenous retroviral familiesNorbert Bannert
Robert Koch Institute, 13353 Berlin, Germany
Annu Rev Genomics Hum Genet 7:149-73. 2006....
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assemblyJörg Votteler
Institute of Virology, Friedrich Alexander University, Erlangen, Germany
Retrovirology 8:11. 2011..In this study, we investigated the importance of the highly conserved serine residue at position 40, which until now has not been assigned to any known function of p6...
Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United StatesWilliam M Switzer
Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Retrovirology 7:57. 2010..Blinded PCR and serologic testing were performed at the US Centers for Disease Control and Prevention (CDC) and at two additional laboratories...
Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 releaseJörg Votteler
Institute of Virology, Friedrich Alexander University, Erlangen, Germany
BMC Biochem 10:12. 2009..Recently, it was reported, that POSH interacts with ALIX and thereby enhances ALIX mediated phenotypes in Drosophila...
Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patientsOliver Hohn
Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
Retrovirology 6:92. 2009..Here, we attempt to measure the prevalence of XMRV in prostate cancer cases in Germany and determine whether an analogous association with the R462Q polymorphism exists...
Molecular cloning and functional characterization of the human endogenous retrovirus K113Nadine Beimforde
Robert Koch Institut, ZBS 4, Nordufer 20, 13353 Berlin, Germany
Virology 371:216-25. 2008..It carries inactivating mutations in the reverse transcriptase gene. These mutations can be reversed to reconstitute the active enzyme, but the reversion is not sufficient to reconstitute replication capacity of the virus...
Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) elementMaja George
Center for HIV and Retrovirology, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
Retrovirology 8:30. 2011..During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown...
Beneficial and detrimental effects of human endogenous retrovirusesReinhard Kurth
Robert Koch Institut, Berlin, Germany
Int J Cancer 126:306-14. 2010..Finally, we will give an outlook in which we will attempt to define priorities for future research...
Reconstitution of the ancestral glycoprotein of human endogenous retrovirus k and modulation of its functional activity by truncation of the cytoplasmic domainKirsten Hanke
Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
J Virol 83:12790-800. 2009....
Origin of XMRV and its demise as a human pathogen associated with chronic fatigue syndromeOliver Hohn
Center for HIV and Retrovirology, Robert Koch Institute, Berlin, Germany
Viruses 3:1312-9. 2011..Furthermore, Paprotka et al's identification of XMRV's origin and the phylogenetic analysis of known XMRV sequences are further nails in the coffin to the notion that XMRV is a clinically relevant infectious human retrovirus...
No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitroOliver Hohn
Centre for Biological Security 4, Robert Koch Institute, Berlin, Germany
PLoS ONE 5:e15632. 2010..Here we report the results of efforts to detect antibody responses and viral sequences in samples from a cohort of German CFS and relapsing remitting multiple sclerosis (MS) patients with fatigue symptoms...
The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT)Kirsten Hanke
Center for HIV and Retrovirology, Robert Koch Institute, Berlin
Int J Cancer 132:556-67. 2013..On the basis of our findings we propose a "vicious cycle" model of Rec-driven hyperactivation of the AR leading to increased cell proliferation, inhibition of apoptosis and eventually to tumor induction or promotion...
FliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophilaTino Schulz
Cellular Interactions of Bacterial Pathogens, Centre for Biological Security, Division 2 ZBS2, Robert Koch Institute, Berlin, Germany
Arch Microbiol 194:977-89. 2012..In addition, we showed for the first time the presence of a straight hook at the pole of the non-flagellated ΔfliA and ΔfliD mutant strains by electron microscopy, indicating the presence of an intact basal body in these strains...
Stimulation of IgY responses in gene gun immunized laying hens by combined administration of vector DNA coding for the target antigen Botulinum toxin A1 and for avian cytokine adjuvantsLars Niederstadt
FU Berlin, Fachbereich Biologie, Chemie, Pharmazie, Berlin, Germany
J Immunol Methods 382:58-67. 2012..4× by the IL-1β adjuvant vector and increased by 3.8× by the IL-6 vector. Finally, although hens receiving the IL-1β adjuvant had laying capacities above the average, hens receiving the IL-6 adjuvant experienced laying problems...
Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) TrollBritta Dieckhoff
Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
Vet Microbiol 123:53-68. 2007..Genomic RNA of PERV-A, -B and -C were found in pelleted virus particles. Although PERV expression was elevated in melanomas and pulmonary metastasis-derived cell cultures, the function of the virus in tumour development is still unclear...
Development of antibodies against anthrose tetrasaccharide for specific detection of Bacillus anthracis sporesAndrea Kuehn
Robert Koch Institut, Nordufer 20, Berlin D 13353, Germany
Clin Vaccine Immunol 16:1728-37. 2009..Moreover, the antibodies generated proved functional in a new capture assay for B. anthracis spores and could therefore be useful for the detection of spores in complex samples...
Evaluation of tip-enhanced Raman spectroscopy for characterizing different virus strainsPeter Hermann
P25 Biomedical Spectroscopy, Robert Koch Institute, Nordufer 20, D 13353 Berlin, Germany
Analyst 136:1148-52. 2011..These spectral variations were higher for the larger avipoxvirus particles (∅≈350 nm) than for the smaller adeno-associated virus particles (∅≈26 nm)...
Shedding and transmission of novel influenza virus A/H1N1 infection in households--Germany, 2009Thorsten Suess
Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
Am J Epidemiol 171:1157-64. 2010..Compared with other nasopharyngeal specimen types, nasal wash was the most sensitive. These results support the notion that epidemiologic and virologic characteristics of NIV are in many aspects similar to those of seasonal influenza...
Transspecies transmission of the endogenous koala retrovirusUwe Fiebig
Robert Koch Institute, Nordufer 20, D 13353 Berlin, Germany
J Virol 80:5651-4. 2006..Finally, evidence for immunosuppressive properties of the KoRV was obtained...
Orbus hercynius gen. nov., sp. nov., isolated from faeces of wild boar, is most closely related to members of the orders 'Enterobacteriales' and PasteurellalesMaria Volkmann
Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany
Int J Syst Evol Microbiol 60:2601-5. 2010..nov., sp. nov. is proposed. The type strain of the type species is CN3(T) (=DSM 22228(T)=CCUG 57622(T)). Classification of the novel species to the family and order level will require further investigations...
MALDI-TOF mass spectrometry compatible inactivation method for highly pathogenic microbial cells and sporesPeter Lasch
P25, ZBS2, and ZBS4, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
Anal Chem 80:2026-34. 2008..This MALDI-TOF/ICMS compatible sample preparation protocol is simple and rapid (30 min) and assures reliable inactivation of vegetative cells and spores of highly pathogenic (BSL-3) microorganisms...
