Norbert Bannert

Summary

Affiliation: Robert Koch-Institut
Country: Germany

Publications

  1. pmc Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
    Claudia Chudak
    Department for HIV and other Retroviruses, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 10:140. 2013
  2. pmc LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
    Belete Ayele Desimmie
    Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Virology and Gene Therapy, KU Leuven, Leuven, Flanders, Belgium
    Retrovirology 10:57. 2013
  3. ncbi request reprint PDZ Domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits
    Norbert Bannert
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    J Biol Chem 278:42190-9. 2003
  4. ncbi request reprint The evolutionary dynamics of human endogenous retroviral families
    Norbert Bannert
    Robert Koch Institute, 13353 Berlin, Germany
    Annu Rev Genomics Hum Genet 7:149-73. 2006
  5. pmc Retroelements and the human genome: new perspectives on an old relation
    Norbert Bannert
    Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    Proc Natl Acad Sci U S A 101:14572-9. 2004
  6. pmc Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    Retrovirology 8:11. 2011
  7. pmc Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Retrovirology 7:57. 2010
  8. pmc Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    BMC Biochem 10:12. 2009
  9. pmc Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients
    Oliver Hohn
    Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 6:92. 2009
  10. pmc Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element
    Maja George
    Center for HIV and Retrovirology, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 8:30. 2011

Collaborators

Detail Information

Publications27

  1. pmc Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
    Claudia Chudak
    Department for HIV and other Retroviruses, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 10:140. 2013
    ..Although the L-domains of exogenous retroviruses have been studied comprehensively, little is known about these motifs in endogenous human retroviruses...
  2. pmc LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
    Belete Ayele Desimmie
    Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Virology and Gene Therapy, KU Leuven, Leuven, Flanders, Belgium
    Retrovirology 10:57. 2013
    ..They block HIV-1 integration by abrogating the interaction between LEDGF/p75 and IN as well as by allosterically inhibiting the catalytic activity of IN...
  3. ncbi request reprint PDZ Domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits
    Norbert Bannert
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    J Biol Chem 278:42190-9. 2003
    ..Alternatively, an intracellular complex of npro-IL-16, ion channels, and components of myosin motors in neurons suggests a role in protein targeting...
  4. ncbi request reprint The evolutionary dynamics of human endogenous retroviral families
    Norbert Bannert
    Robert Koch Institute, 13353 Berlin, Germany
    Annu Rev Genomics Hum Genet 7:149-73. 2006
    ....
  5. pmc Retroelements and the human genome: new perspectives on an old relation
    Norbert Bannert
    Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    Proc Natl Acad Sci U S A 101:14572-9. 2004
    ..The remarkable progress in the analysis of host genomes has brought to light the significant impact of HERVs and other retroelements on genetic variation, genome evolution, and gene regulation...
  6. pmc Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    Retrovirology 8:11. 2011
    ..In this study, we investigated the importance of the highly conserved serine residue at position 40, which until now has not been assigned to any known function of p6...
  7. pmc Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Retrovirology 7:57. 2010
    ..Blinded PCR and serologic testing were performed at the US Centers for Disease Control and Prevention (CDC) and at two additional laboratories...
  8. pmc Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    BMC Biochem 10:12. 2009
    ..Recently, it was reported, that POSH interacts with ALIX and thereby enhances ALIX mediated phenotypes in Drosophila...
  9. pmc Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients
    Oliver Hohn
    Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 6:92. 2009
    ..Here, we attempt to measure the prevalence of XMRV in prostate cancer cases in Germany and determine whether an analogous association with the R462Q polymorphism exists...
  10. pmc Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element
    Maja George
    Center for HIV and Retrovirology, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 8:30. 2011
    ..During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown...
  11. ncbi request reprint Molecular cloning and functional characterization of the human endogenous retrovirus K113
    Nadine Beimforde
    Robert Koch Institut, ZBS 4, Nordufer 20, 13353 Berlin, Germany
    Virology 371:216-25. 2008
    ..It carries inactivating mutations in the reverse transcriptase gene. These mutations can be reversed to reconstitute the active enzyme, but the reversion is not sufficient to reconstitute replication capacity of the virus...
  12. pmc Staufen-1 interacts with the human endogenous retrovirus family HERV-K(HML-2) rec and gag proteins and increases virion production
    Kirsten Hanke
    Division for HIV and Other Retroviruses, Robert Koch Institute, Berlin, Germany
    J Virol 87:11019-30. 2013
    ..Our results suggest a new role for Staufen-1 as a cellular Rec and HERV-K(HML-2) Gag cofactor. ..
  13. doi request reprint A novel small animal model to study the replication of simian foamy virus in vivo
    Rico Blochmann
    FG18 HIV and Other Retroviruses, Robert Koch Institute, Berlin, Germany
    Virology 448:65-73. 2014
    ..The results strongly indicate establishment of a persistent infection in hamsters. These studies provide a further small animal model for studying FV-based vectors in addition to the established models...
  14. pmc Reconstitution of the ancestral glycoprotein of human endogenous retrovirus k and modulation of its functional activity by truncation of the cytoplasmic domain
    Kirsten Hanke
    Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
    J Virol 83:12790-800. 2009
    ....
  15. doi request reprint Beneficial and detrimental effects of human endogenous retroviruses
    Reinhard Kurth
    Robert Koch Institut, Berlin, Germany
    Int J Cancer 126:306-14. 2010
    ..Finally, we will give an outlook in which we will attempt to define priorities for future research...
  16. pmc Origin of XMRV and its demise as a human pathogen associated with chronic fatigue syndrome
    Oliver Hohn
    Center for HIV and Retrovirology, Robert Koch Institute, Berlin, Germany
    Viruses 3:1312-9. 2011
    ..Furthermore, Paprotka et al's identification of XMRV's origin and the phylogenetic analysis of known XMRV sequences are further nails in the coffin to the notion that XMRV is a clinically relevant infectious human retrovirus...
  17. pmc No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitro
    Oliver Hohn
    Centre for Biological Security 4, Robert Koch Institute, Berlin, Germany
    PLoS ONE 5:e15632. 2010
    ..Here we report the results of efforts to detect antibody responses and viral sequences in samples from a cohort of German CFS and relapsing remitting multiple sclerosis (MS) patients with fatigue symptoms...
  18. ncbi request reprint Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll
    Britta Dieckhoff
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    Vet Microbiol 123:53-68. 2007
    ..Genomic RNA of PERV-A, -B and -C were found in pelleted virus particles. Although PERV expression was elevated in melanomas and pulmonary metastasis-derived cell cultures, the function of the virus in tumour development is still unclear...
  19. doi request reprint The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT)
    Kirsten Hanke
    Center for HIV and Retrovirology, Robert Koch Institute, Berlin
    Int J Cancer 132:556-67. 2013
    ..On the basis of our findings we propose a "vicious cycle" model of Rec-driven hyperactivation of the AR leading to increased cell proliferation, inhibition of apoptosis and eventually to tumor induction or promotion...
  20. doi request reprint Evaluation of tip-enhanced Raman spectroscopy for characterizing different virus strains
    Peter Hermann
    P25 Biomedical Spectroscopy, Robert Koch Institute, Nordufer 20, D 13353 Berlin, Germany
    Analyst 136:1148-52. 2011
    ..These spectral variations were higher for the larger avipoxvirus particles (∅≈350 nm) than for the smaller adeno-associated virus particles (∅≈26 nm)...
  21. doi request reprint FliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila
    Tino Schulz
    Cellular Interactions of Bacterial Pathogens, Centre for Biological Security, Division 2 ZBS2, Robert Koch Institute, Berlin, Germany
    Arch Microbiol 194:977-89. 2012
    ..In addition, we showed for the first time the presence of a straight hook at the pole of the non-flagellated ΔfliA and ΔfliD mutant strains by electron microscopy, indicating the presence of an intact basal body in these strains...
  22. doi request reprint Stimulation of IgY responses in gene gun immunized laying hens by combined administration of vector DNA coding for the target antigen Botulinum toxin A1 and for avian cytokine adjuvants
    Lars Niederstadt
    FU Berlin, Fachbereich Biologie, Chemie, Pharmazie, Berlin, Germany
    J Immunol Methods 382:58-67. 2012
    ..4× by the IL-1β adjuvant vector and increased by 3.8× by the IL-6 vector. Finally, although hens receiving the IL-1β adjuvant had laying capacities above the average, hens receiving the IL-6 adjuvant experienced laying problems...
  23. pmc Development of antibodies against anthrose tetrasaccharide for specific detection of Bacillus anthracis spores
    Andrea Kuehn
    Robert Koch Institut, Nordufer 20, Berlin D 13353, Germany
    Clin Vaccine Immunol 16:1728-37. 2009
    ..Moreover, the antibodies generated proved functional in a new capture assay for B. anthracis spores and could therefore be useful for the detection of spores in complex samples...
  24. doi request reprint Shedding and transmission of novel influenza virus A/H1N1 infection in households--Germany, 2009
    Thorsten Suess
    Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Am J Epidemiol 171:1157-64. 2010
    ..Compared with other nasopharyngeal specimen types, nasal wash was the most sensitive. These results support the notion that epidemiologic and virologic characteristics of NIV are in many aspects similar to those of seasonal influenza...
  25. doi request reprint MALDI-TOF mass spectrometry compatible inactivation method for highly pathogenic microbial cells and spores
    Peter Lasch
    P25, ZBS2, and ZBS4, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    Anal Chem 80:2026-34. 2008
    ..This MALDI-TOF/ICMS compatible sample preparation protocol is simple and rapid (30 min) and assures reliable inactivation of vegetative cells and spores of highly pathogenic (BSL-3) microorganisms...
  26. pmc Transspecies transmission of the endogenous koala retrovirus
    Uwe Fiebig
    Robert Koch Institute, Nordufer 20, D 13353 Berlin, Germany
    J Virol 80:5651-4. 2006
    ..Finally, evidence for immunosuppressive properties of the KoRV was obtained...
  27. doi request reprint Orbus hercynius gen. nov., sp. nov., isolated from faeces of wild boar, is most closely related to members of the orders 'Enterobacteriales' and Pasteurellales
    Maria Volkmann
    Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany
    Int J Syst Evol Microbiol 60:2601-5. 2010
    ..nov., sp. nov. is proposed. The type strain of the type species is CN3(T) (=DSM 22228(T)=CCUG 57622(T)). Classification of the novel species to the family and order level will require further investigations...