Research Topics
Species | Rudolf RichterSummaryCountry: Germany Publications
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Detail Information
Publications
Posttranslationally processed forms of the human chemokine HCC-1R Richter
Lower Saxony Institute for Peptide Research, Feodor Lynen Strasse 31, D 30625 Hannover, Germany
Biochemistry 39:10799-805. 2000..Our data imply that HCC-1 (1-74), HCC-1 (3-74), HCC-1 (4-74) and glycosylated HCC-1 (1-74) circulate in human blood. The N-terminal processing and modification of HCC-1 might be of importance in displaying its full biological activity...
Quantum proteolytic activation of chemokine CCL15 by neutrophil granulocytes modulates mononuclear cell adhesivenessRudolf Richter
IPF PharmaCeuticals GmbH, Hannover, Germany
J Immunol 175:1599-608. 2005..Thus, our findings indicate that activation of monocytes by neutrophils is at least in part induced by quantum proteolytic processing of circulating or endothelium-bound CCL15 by neutrophil cathepsin G...
Increase of expression and activation of chemokine CCL15 in chronic renal failureRudolf Richter
IPF PharmaCeuticals GmbH, Hannover, Germany
Biochem Biophys Res Commun 345:1504-12. 2006..Our results point to an involvement of the CCL15-CCR1 axis in the pathophysiology of CRF...
Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28Rudolf Richter
Institute of Transfusion Medicine and Immune Hematology, Blood Donation Service of the German Red Cross, Frankfurt, Germany
J Immunol 183:1229-37. 2009..Our results suggest that the activity of CCL14a might be regulated by stringent proteolytic activation and inactivation steps...
CCR1- and CCR5-mediated inactivation of leukocytes by a nonglycosaminoglycan (non-GAG)-binding variant of n-nonanoyl-CCL14 (NNY-CCL14)Shipra Gupta
Center of Pharmacology and Toxicology, Clinic of Immunology and Rheumatology, Hannover Medical School, Feodor Lynen Strasse 31, 30625 Hannover, Germany
J Leukoc Biol 88:383-92. 2010..When administered systemically, NNY-CCL14(G,A) may modulate leukocyte functions prior to their interaction with other endothelium-bound chemokines expressed under pathophysiological conditions, such as allergic inflammation...
Cloning, expression, and functional characterization of cynomolgus monkey (Macaca fascicularis) CC chemokine receptor 1Shipra Gupta
Department of Dermatology and Allergology, An-Institut, Hannover Medical School, Germany
J Leukoc Biol 78:1175-84. 2005....
