Christian Luckhaus

Summary

Affiliation: Rhine Clinic Bonn
Country: Germany

Publications

  1. doi request reprint The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Psychiatry Res 183:44-51. 2010
  2. doi request reprint Nicotinic acetylcholine receptor expression on B-lymphoblasts of healthy versus schizophrenic subjects stratified for smoking: [3H]-nicotine binding is decreased in schizophrenia and correlates with negative symptoms
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf, 40620 Duesseldorf, Germany
    J Neural Transm 119:587-95. 2012
  3. doi request reprint A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variables
    C Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Eur J Neurol 17:1437-44. 2010
  4. ncbi request reprint Blood biomarkers of osteoporosis in mild cognitive impairment and Alzheimer's disease
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Bergische Landstrasse 2, Duesseldorf 40629, Germany
    J Neural Transm 116:905-11. 2009
  5. ncbi request reprint Brugada syndrome as a potential cardiac risk factor during electroconvulsive therapy (ECT)
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    World J Biol Psychiatry 9:150-3. 2008
  6. doi request reprint Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer's dementia by perfusion-weighted magnetic resonance imaging
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Bergische Landstrasse 2, D 40629, Duesseldorf, Germany
    Neuroimage 40:495-503. 2008
  7. doi request reprint Quantitative EEG in progressing vs stable mild cognitive impairment (MCI): results of a 1-year follow-up study
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Int J Geriatr Psychiatry 23:1148-55. 2008
  8. ncbi request reprint Facial affect recognition performance and event-related potentials in violent and non-violent schizophrenia patients
    Nicole Frommann
    Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University of Dusseldorf, Dusseldorf, Germany
    Neuropsychobiology 68:139-45. 2013
  9. doi request reprint Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network
    Johannes Kornhuber
    Department of Psychiatry and Psychotherapy, University Erlangen, Erlangen, Germany
    Dement Geriatr Cogn Disord 27:404-17. 2009
  10. ncbi request reprint Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load
    Jens Wiltfang
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurochem 101:1053-9. 2007

Detail Information

Publications17

  1. doi request reprint The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Psychiatry Res 183:44-51. 2010
    ..The data also support the concept of functional compensatory brain activation and the diaschisis hypothesis as relevant in incipient and early AD...
  2. doi request reprint Nicotinic acetylcholine receptor expression on B-lymphoblasts of healthy versus schizophrenic subjects stratified for smoking: [3H]-nicotine binding is decreased in schizophrenia and correlates with negative symptoms
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf, 40620 Duesseldorf, Germany
    J Neural Transm 119:587-95. 2012
    ..38 fmol/10(6) cells, P = 0.038). Our data are in further support of a decrease of nicotinic acetylcholine receptor expression in schizophrenia linked to negative psychotic symptoms, which may be counter-regulated by nicotine exposure...
  3. doi request reprint A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variables
    C Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Eur J Neurol 17:1437-44. 2010
    ..We compared single variables and combinations regarding their power for optimizing diagnostic accuracy...
  4. ncbi request reprint Blood biomarkers of osteoporosis in mild cognitive impairment and Alzheimer's disease
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Bergische Landstrasse 2, Duesseldorf 40629, Germany
    J Neural Transm 116:905-11. 2009
    ....
  5. ncbi request reprint Brugada syndrome as a potential cardiac risk factor during electroconvulsive therapy (ECT)
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    World J Biol Psychiatry 9:150-3. 2008
    ..However, as the presented case illustrates, this syndrome should be considered as a rare but potentially severe cardiac risk factor in the context of ECT...
  6. doi request reprint Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer's dementia by perfusion-weighted magnetic resonance imaging
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Bergische Landstrasse 2, D 40629, Duesseldorf, Germany
    Neuroimage 40:495-503. 2008
    ..This method may thus be useful in both research and clinical applications to detect early functional brain changes in the pathogenesis of dementias...
  7. doi request reprint Quantitative EEG in progressing vs stable mild cognitive impairment (MCI): results of a 1-year follow-up study
    Christian Luckhaus
    Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
    Int J Geriatr Psychiatry 23:1148-55. 2008
    ..The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI...
  8. ncbi request reprint Facial affect recognition performance and event-related potentials in violent and non-violent schizophrenia patients
    Nicole Frommann
    Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University of Dusseldorf, Dusseldorf, Germany
    Neuropsychobiology 68:139-45. 2013
    ..Larger impairment in AR performance combined with higher salience and arousal may contribute to the occurrence of violent acts in schizophrenia patients. ..
  9. doi request reprint Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network
    Johannes Kornhuber
    Department of Psychiatry and Psychotherapy, University Erlangen, Erlangen, Germany
    Dement Geriatr Cogn Disord 27:404-17. 2009
    ..The German Dementia Competence Network (DCN) has established procedures for standardized multicenter acquisition of clinical, biological and imaging data, for centralized data management, and for the evaluation of new treatments...
  10. ncbi request reprint Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load
    Jens Wiltfang
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurochem 101:1053-9. 2007
    ..We conclude that the amyloid beta concentration ratio should replace the 'raw' concentrations of corresponding A beta peptides to improve reliability of the neurochemical dementia diagnosis...
  11. doi request reprint Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form
    Hans Wolfgang Klafki
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    J Alzheimers Dis 18:613-22. 2009
    ....
  12. ncbi request reprint Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study
    Piotr Lewczuk
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    Neurobiol Aging 29:812-8. 2008
    ..9 pg/mL. These cutoff values were also applied to discriminate between MCI-AD and MCI-O subjects. Simultaneous measurement of the biomarkers significantly improves management of the samples and quality control of the assays' performance...
  13. doi request reprint Multielectrode array analysis of cerebrospinal fluid in Alzheimer's disease versus mild cognitive impairment: a potential diagnostic and treatment biomarker
    Philipp Görtz
    Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
    Biochem Biophys Res Commun 434:293-7. 2013
    ..The findings of this pilot study may set the stage for a unique and straightforward diagnostic bioassay of AD with particular value in the differential diagnosis to MCI and as a much needed biomarker for clinical trials...
  14. doi request reprint Training of affect recognition in schizophrenia patients with violent offences: behavioral treatment effects and electrophysiological correlates
    Christian Luckhaus
    a Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
    Soc Neurosci 8:505-14. 2013
    ..TAR treatment might enable subjects with schizophrenia and a disposition to violence to reach a higher degree of deliberation of their reactive behavior to facial affect stimuli...
  15. doi request reprint Circadian rhythm of neutrophil counts and granulocyte macrophage-colony stimulating factor (GM-CSF) under clozapine treatment: a case report
    Stefano Ferrea
    Department of Psychiatry and Psychotherapy, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    World J Biol Psychiatry 11:511-3. 2010
    ....
  16. ncbi request reprint Estrogen Receptor 1 gene (ESR1) variants in Alzheimer's disease. Results of a meta-analysis
    Christian Luckhaus
    Department of Psychiatry, University of Duesseldorf, Duesseldorf, Germany
    Aging Clin Exp Res 19:165-8. 2007
    ..The present study was conceived to review evidence of ESR association with Alzheimer's disease (AD) which could account for the variability observed in estrogen treatment outcome...
  17. ncbi request reprint Estrogen receptor beta gene (ESRbeta) 3'-UTR variants in Alzheimer disease
    Christian Luckhaus
    Alzheimer Dis Assoc Disord 20:322-3. 2006