Jörg Reutershan

Summary

Country: Germany

Publications

  1. ncbi request reprint Non-invasive determination of effective pulmonary blood flow: evaluation of a simplified rebreathing method
    J Reutershan
    Department of Anaesthesiology and Intensive Care, University Hospital of Tubingen, Germany
    J Med Eng Technol 27:194-9. 2003
  2. ncbi request reprint [Noninvasive determination of cardiac output in ventilated patients . Clinical evaluation of a simplified quick method]
    J Reutershan
    Abteilung für Anaesthesiologie und Intensivmedizin, Universitatsklinikum Tubingen, Germany
    Anaesthesist 52:778-86. 2003
  3. ncbi request reprint Non-invasive measurement of pulmonary blood flow during prone positioning in patients with early acute respiratory distress syndrome
    Jörg Reutershan
    Department of Anaesthesiology and Intensive Care Medicine, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Clin Sci (Lond) 106:3-10. 2004
  4. ncbi request reprint Alveolar recruitment during prone position: time matters
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Clin Sci (Lond) 110:655-63. 2006
  5. ncbi request reprint Protective effects of isoflurane pretreatment in endotoxin-induced lung injury
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia Health System, USA
    Anesthesiology 104:511-7. 2006
  6. doi request reprint Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation
    Rosalyn Wagner
    Dept of Anesthesiology and Intensive Care Medicine, University Hospital of Tubingen, Germany
    Am J Physiol Lung Cell Mol Physiol 299:L502-12. 2010
  7. pmc DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Tubingen, Germany
    Eur J Immunol 39:1597-607. 2009
  8. doi request reprint Adenosine receptor A1 regulates polymorphonuclear cell trafficking and microvascular permeability in lipopolysaccharide-induced lung injury
    Kristian Christos Ngamsri
    Department of Anesthesiology and Intensive Care Medicine, University Hospital of Tubingen, Tubingen, Germany
    J Immunol 185:4374-84. 2010
  9. ncbi request reprint Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA
    J Immunol 179:1254-63. 2007
  10. pmc Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury
    Alaa S Awad
    Division of Nephrology, Department of Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA
    Kidney Int 75:689-98. 2009

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Non-invasive determination of effective pulmonary blood flow: evaluation of a simplified rebreathing method
    J Reutershan
    Department of Anaesthesiology and Intensive Care, University Hospital of Tubingen, Germany
    J Med Eng Technol 27:194-9. 2003
    ..To evaluate a new technical approach to measuring effective pulmonary blood flow (PBF) in mechanically ventilated patients...
  2. ncbi request reprint [Noninvasive determination of cardiac output in ventilated patients . Clinical evaluation of a simplified quick method]
    J Reutershan
    Abteilung für Anaesthesiologie und Intensivmedizin, Universitatsklinikum Tubingen, Germany
    Anaesthesist 52:778-86. 2003
    ..This study was performed to evaluate a new simplified rebreathing method to determine cardiac output (CO) in mechanically ventilated patients...
  3. ncbi request reprint Non-invasive measurement of pulmonary blood flow during prone positioning in patients with early acute respiratory distress syndrome
    Jörg Reutershan
    Department of Anaesthesiology and Intensive Care Medicine, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Clin Sci (Lond) 106:3-10. 2004
    ..It is able to reliably reflect changes in PBF induced by prone positioning. Moreover, measuring PBF might be a promising tool to identify responders to prone therapy...
  4. ncbi request reprint Alveolar recruitment during prone position: time matters
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Clin Sci (Lond) 110:655-63. 2006
    ..Its measurement might be useful to apply prone positioning more individually and might also help to identify responders...
  5. ncbi request reprint Protective effects of isoflurane pretreatment in endotoxin-induced lung injury
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia Health System, USA
    Anesthesiology 104:511-7. 2006
    ..Their protective role in lung injury, however, remains to be elucidated. The authors hypothesized that in the lung, isoflurane pretreatment may attenuate neutrophil infiltration and reduce endotoxin-induced injury...
  6. doi request reprint Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation
    Rosalyn Wagner
    Dept of Anesthesiology and Intensive Care Medicine, University Hospital of Tubingen, Germany
    Am J Physiol Lung Cell Mol Physiol 299:L502-12. 2010
    ..Together, our results shed new light on the role of A(3) in LPS-induced PMN trafficking in the lung and suggest pharmacological modulation of A(3)-dependent pathways as a promising approach in lung inflammation...
  7. pmc DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Tubingen, Germany
    Eur J Immunol 39:1597-607. 2009
    ..These findings show how DARC regulates lung inflammation by controlling the distribution and presentation of chemokines that bind CXCR2...
  8. doi request reprint Adenosine receptor A1 regulates polymorphonuclear cell trafficking and microvascular permeability in lipopolysaccharide-induced lung injury
    Kristian Christos Ngamsri
    Department of Anesthesiology and Intensive Care Medicine, University Hospital of Tubingen, Tubingen, Germany
    J Immunol 185:4374-84. 2010
    ..Our data reveal what we believe to be a previously unrecognized distinct role of A1AR for PMN trafficking and endothelial integrity in a model of acute lung injury...
  9. ncbi request reprint Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA
    J Immunol 179:1254-63. 2007
    ..These findings were confirmed in A2a(flox/flox) x LysM-cre mice. ATL202 was only effective when A2a was present on BM-derived cells. A2a agonists may be effective at curbing inflammatory lung tissue damage...
  10. pmc Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury
    Alaa S Awad
    Division of Nephrology, Department of Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA
    Kidney Int 75:689-98. 2009
    ..Our findings suggest there is a sequential recruitment and transmigration of neutrophils from the vasculature into the kidney interstitium at the site of tissue injury following renal ischemia-reperfusion...
  11. pmc Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK
    Rebecca Stockton
    Robert M Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA
    Mol Biol Cell 18:2346-55. 2007
    ..We conclude that the PAK-PIX-GIT1 complex is critical for Erk-dependent myosin phosphorylation and vascular permeability...
  12. ncbi request reprint Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, Department of Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA
    Am J Physiol Lung Cell Mol Physiol 289:L807-15. 2005
    ..These findings confirm LPS-induced migration of PMN into the lung. For the first time, distinct transmigration steps into the different lung compartments are characterized in vivo...
  13. pmc Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908 1394, USA
    Am J Respir Crit Care Med 175:1027-35. 2007
    ..p21-Activated kinase (PAK) is an effector of small GTPases and has been implicated in cell migration...
  14. doi request reprint Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Tubingen, Germany
    FASEB J 23:473-82. 2009
    ..Taken together, these data reveal a previously unrecognized role for CD39 and CD73 in attenuating PMN trafficking into the lungs during LPS-induced lung injury and suggest treatment with their soluble compounds as a therapeutic strategy...
  15. ncbi request reprint CXCR2--the receptor to hit?
    Jörg Reutershan
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Drug News Perspect 19:615-23. 2006
    ..This review will summarize current knowledge about CXCR2 in inflammatory diseases and discuss its potential as a pharmaceutical target...
  16. pmc Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung
    Jörg Reutershan
    Robert M Berne Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908 1394, USA
    J Clin Invest 116:695-702. 2006
    ..Our data revealed what we believe to be a previously unrecognized role of endothelial and epithelial CXCR2 in LPS-induced PMN recruitment and lung injury...
  17. ncbi request reprint Penetration of intravenous hydroxyethyl starch into the cerebrospinal fluid in patients with impaired blood-brain barrier function
    Hans Jürgen Dieterich
    Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Germany
    Anesth Analg 96:1150-4, table of contents. 2003
    ..Further study is required to determine whether HES penetrates into the intracranial interstitium, despite the absence of HES in the CSF...
  18. doi request reprint Adenosine receptor A2b on hematopoietic cells mediates LPS-induced migration of PMNs into the lung interstitium
    Franziska M Konrad
    Dept of Anesthesiology and Intensive Care Medicine, Univ of Tübingen, Tubingen, Germany
    Am J Physiol Lung Cell Mol Physiol 303:L425-38. 2012
    ....
  19. pmc Bench-to-bedside review: acute respiratory distress syndrome - how neutrophils migrate into the lung
    Jörg Reutershan
    University of Virginia Health System, Cardiovascular Research Center, Charlottesville, Virginia, USA
    Crit Care 8:453-61. 2004
    ..The mechanisms of neutrophil entry into the lung interstitial space are currently unknown. This review summarizes mechanisms of neutrophil trafficking in the inflamed lung and their relevance to lung injury...
  20. doi request reprint Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent
    Franziska M Konrad
    1Department of Anesthesiology and Intensive Care Medicine, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany e mail address
    FASEB J 27:3524-35. 2013
    ..Konrad, F. M., Neudeck, G., Vollmer, I., Ngamsri, K. C., Thiel, M., Reutershan, J. Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent. ..
  21. pmc Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury?
    Carsten P Schepp
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Tubingen, Hoppe Seyler Strasse, D 72076 Tubingen, Germany
    Crit Care 12:226. 2008
    ....
  22. ncbi request reprint Synthetic colloids attenuate leukocyte-endothelial interactions by inhibition of integrin function
    Boris Nohé
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital, Eberhard Karls University Tuebingen, Germany
    Anesthesiology 103:759-67. 2005
    ..Regarding the widespread use of colloids, the authors performed a laboratory investigation to determine the mechanisms by which synthetic colloids interfere with leukocyte-endothelial interactions...