Research Topics
Genomes and GenesSpecies | Wolfgang RetzSummaryCountry: Germany Publications
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Publications
Emotional dysregulation in adult ADHD: What is the empirical evidence?Wolfgang Retz
Saarland University Hospital, Homburg Saar, Germany
Expert Rev Neurother 12:1241-51. 2012..Thus, there is growing evidence that emotional dysregulation might be recognized as a core feature of ADHD...
Clinical symptoms of ADHD and psychopathy in perpetratorsWolfgang Retz
Neurocenter Institute for Forensic Psychology and Psychiatry, Saarland University Hospital, 66421, Homburg, Saarland, Germany
Atten Defic Hyperact Disord 5:47-57. 2013..Findings on the principal component analysis suggest that ADHD and psychopathy are unrelated on a symptomatic level, with the exception of impulsivity, which is a common feature that seems to combine both constructs...
Assessment of post-excitatory long-interval cortical inhibition in adult attention-deficit/hyperactivity disorderWolfgang Retz
Institute for Forensic Psychology and Psychiatry, Neurocentre, Saarland University Hospital, Bdg 90 3, 66424, Homburg Saar, Germany
Eur Arch Psychiatry Clin Neurosci 262:507-17. 2012..The results support the hypothesis of reduced intracortical inhibition as a correlate of disturbed brain function in adults with ADHD...
Multiscale assessment of treatment efficacy in adults with ADHD: a randomized placebo-controlled, multi-centre study with extended-release methylphenidateWolfgang Retz
Neurocentre, Saarland University Hospital, University of the Saarland, Homburg, Germany
World J Biol Psychiatry 13:48-59. 2012..This trial was performed to test the efficacy and safety of an extended-release formulation of methylphenidate (MPH ER)...
Association of a functional variant of neuronal nitric oxide synthase gene with self-reported impulsiveness, venturesomeness and empathy in male offendersWolfgang Retz
Neurocentre, Institute for Forensic Psychology and Psychiatry, Saarland University Hospital, Homburg, Saar, Germany
J Neural Transm 117:321-4. 2010..The findings give additional evidence that NOS-I is involved in the regulation of impulsive personality traits and support the notion that the NOS1 gene takes part in the regulation of social behavior...
Pharmacological treatment of adult ADHD in EuropeWolfgang Retz
Neurocenter Saarland University Hospital, Homburg Saar, Germany
World J Biol Psychiatry 12:89-94. 2011..Adult ADHD is a reliable and valid diagnosis. The disorder and the co-morbid conditions can place a severe burden on the patients, their families and their partners, requiring adequate treatment...
Association of ADHD with reactive and proactive violent behavior in a forensic populationWolfgang Retz
Institute for Forensic Psychology and Psychiatry, Neurocentre, Saarland University Hospital, Homburg Saar, Germany
Atten Defic Hyperact Disord 2:195-202. 2010..Significant impact of male gender on proactive violence was found. The findings suggest that ADHD is associated with reactive but not proactive violence in aggressive offenders...
Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathologyWolfgang Retz
Institute for Forensic Psychology and Psychiatry, University of the Saarland, Homburg Saar, Germany
Behav Sci Law 22:415-25. 2004..provide evidence for an-at least partial-genetic regulation of violent behavior in a subgroup of male offenders, and (iii). suggest a significant role for 5-HT transporter functionality for violent behavior...
Twenty-four-week treatment with extended release methylphenidate improves emotional symptoms in adult ADHDMichael Rösler
Neurocentre, University Hospital of the Saarland, Homburg Saar
World J Biol Psychiatry 11:709-18. 2010..To assess the medium- to long-term effects of extended release methylphenidate (MPH-ER) on emotional symptoms and other psychopathology frequently seen in ADHD patients, we conducted a large-scale, multicenter treatment study...
A randomised, placebo-controlled, 24-week, study of low-dose extended-release methylphenidate in adults with attention-deficit/hyperactivity disorderMichael Rösler
Neurocenter, Saarland University Hospital, 66421, Homburg Saar, Germany
Eur Arch Psychiatry Clin Neurosci 259:120-9. 2009..Although stimulants and methylphenidate in particular are a common off-label treatment for adult patients with ADHD in European countries, little is known about their long-term efficacy and safety...
A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environmentWolfgang Retz
Institute for Forensic Psychology and Psychiatry, University of the Saarland, Homburg Saar, Germany
Psychiatry Res 158:123-31. 2008..The results support prior findings of association between ADHD and 5-HTTLPR LL-genotype and adverse childhood environment, and they underline the need for further investigation of gene by environment interaction with respect to ADHD...
Attention deficit/hyperactivity disorder in female offenders: prevalence, psychiatric comorbidity and psychosocial implicationsMichael Rösler
Institute for Forensic Psychology and Psychiatry, Neurocenter, Saarland University Hospital, 66421, Homburg Saar, Germany
Eur Arch Psychiatry Clin Neurosci 259:98-105. 2009..The results indicate the need of adequate psychiatric support of female prison inmates including therapeutic programs for ADHD...
Association of attention deficit hyperactivity disorder-related psychopathology and personality traits with the serotonin transporter promoter region polymorphismWolfgang Retz
Institute for Forensic Psychiatry, University of the Saarland, Kirrberger Strasse, 66421 Homburg Saar, Germany
Neurosci Lett 319:133-6. 2002..However, since a dimensional assessment of ADHD-related symptomatology was used in our study instead of a diagnostic approach, we are now on the way in performing further studies regarding diagnostic discrimination and comorbidity...
Reduced cortical inhibition in violent offenders: a study with transcranial magnetic stimulationFlorence Philipp-Wiegmann
Institute of Forensic Psychology and Psychiatry, Neurocentre, Saarland University Hospital, Homburg Saar, Germany
Neuropsychobiology 64:86-92. 2011..We performed a study with transcranial magnetic stimulation on a sample of violent offenders in order to measure cortical inhibition in the motor neuron system that is part of the frontal cortex...
Effects of long-acting methylphenidate in adults with attention deficit hyperactivity disorder: a study with paired-pulse transcranial magnetic stimulationMarc K F Schneider
Institute for Forensic Psychiatry, University of the Saarland, Homburg, Germany
Neuropsychobiology 64:195-201. 2011..Therefore, we investigated the neurophysiological effects of long-acting methylphenidate (LA-Mph) with the ppTMS technique in adult patients with ADHD...
The relation of ADHD and violent aggression: What can we learn from epidemiological and genetic studies?Wolfgang Retz
Institute for Forensic Psychology and Psychiatry, Neurocenter Saarland University Hospital, Homburg Saar, Germany
Int J Law Psychiatry 32:235-43. 2009..The impact of genetic research on forensic psychiatry and future directions of neurobiological research are discussed...
Anatomical and functional brain imaging in adult attention-deficit/hyperactivity disorder (ADHD)--a neurological viewMarc Schneider
Neurocentre Institute of Forensic Psychology and Psychiatry, University of the Saarland, Building 90 3, 66421, Homburg Saar, Germany
Eur Arch Psychiatry Clin Neurosci 256:i32-41. 2006..The cerebellum, and its role in affect and cognition, is also persistently implicated in the pathology of ADHD...
Impairment of fronto-striatal and parietal cerebral networks correlates with attention deficit hyperactivity disorder (ADHD) psychopathology in adults - a functional magnetic resonance imaging (fMRI) studyMarc F Schneider
Neurocentre, Institute for Forensic Psychology and Psychiatry, Saarland University Hospital, Homburg, Germany
Psychiatry Res 183:75-84. 2010....
