Silke Feuerriegel

Summary

Affiliation: Research Center Borstel
Country: Germany

Publications

  1. pmc Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Germany
    BMC Microbiol 12:90. 2012
  2. doi request reprint Role of global regulator Rma for multidrug efflux-mediated fluoroquinolone resistance in Salmonella
    Silke Feuerriegel
    Pharmaceutical Biology and Microbiology, University of Hamburg, Bundesstrasse, Hamburg, Germany
    Microb Drug Resist 14:259-63. 2008
  3. pmc Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment
    Silke Feuerriegel
    Research Center Borstel, National Reference Center for Mycobacteria, Parkallee 18, 23845 Borstel, Germany
    Antimicrob Agents Chemother 53:3353-6. 2009
  4. ncbi request reprint embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation
    Claudia Plinke
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    J Antimicrob Chemother 65:1359-67. 2010
  5. pmc Impact of Fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Parkallee 18, 23845 Borstel, Germany
    Antimicrob Agents Chemother 55:5718-22. 2011
  6. pmc rplC T460C identified as a dominant mutation in linezolid-resistant Mycobacterium tuberculosis strains
    Patrick Beckert
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    Antimicrob Agents Chemother 56:2743-5. 2012
  7. pmc Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Parkallee 1, Borstel, Germany
    Antimicrob Agents Chemother 54:4794-8. 2010
  8. pmc High resolution discrimination of clinical Mycobacterium tuberculosis complex strains based on single nucleotide polymorphisms
    Susanne Homolka
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    PLoS ONE 7:e39855. 2012
  9. ncbi request reprint Phylogenetic polymorphisms in antibiotic resistance genes of the Mycobacterium tuberculosis complex
    Silke Feuerriegel
    Molecular Mycobacteriology, Borstel, Germany
    J Antimicrob Chemother 69:1205-10. 2014

Collaborators

Detail Information

Publications9

  1. pmc Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Germany
    BMC Microbiol 12:90. 2012
    ..Of the strains investigated 50 were either mono- or poly-resistant to isoniazid, rifampin, streptomycin, ethambutol and pyrazinamide or MDR and 47 fully susceptible strains served as controls...
  2. doi request reprint Role of global regulator Rma for multidrug efflux-mediated fluoroquinolone resistance in Salmonella
    Silke Feuerriegel
    Pharmaceutical Biology and Microbiology, University of Hamburg, Bundesstrasse, Hamburg, Germany
    Microb Drug Resist 14:259-63. 2008
    ..Thus, the global regulator Rma is important in Salmonella concerning elevated expression of several mdr efflux pumps and hence resulting increase in antibiotic resistance...
  3. pmc Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment
    Silke Feuerriegel
    Research Center Borstel, National Reference Center for Mycobacteria, Parkallee 18, 23845 Borstel, Germany
    Antimicrob Agents Chemother 53:3353-6. 2009
    ..The mechanisms that confer amikacin resistance in this setting remain unclear...
  4. ncbi request reprint embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation
    Claudia Plinke
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    J Antimicrob Chemother 65:1359-67. 2010
    ..Here, other mutations in the embCAB operon are suggested to be involved in resistance development...
  5. pmc Impact of Fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Parkallee 18, 23845 Borstel, Germany
    Antimicrob Agents Chemother 55:5718-22. 2011
    ..canettii infections. This finding has implications for the design of multiple ongoing clinical trials...
  6. pmc rplC T460C identified as a dominant mutation in linezolid-resistant Mycobacterium tuberculosis strains
    Patrick Beckert
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    Antimicrob Agents Chemother 56:2743-5. 2012
    ....
  7. pmc Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance
    Silke Feuerriegel
    Molecular Mycobacteriology, Research Center Borstel, Parkallee 1, Borstel, Germany
    Antimicrob Agents Chemother 54:4794-8. 2010
    ..These findings challenge some of the previous understanding of PAS resistance and, as a consequence, warrant further in-depth investigations of the genetic variation in PAS-resistant clinical isolates and spontaneous mutants...
  8. pmc High resolution discrimination of clinical Mycobacterium tuberculosis complex strains based on single nucleotide polymorphisms
    Susanne Homolka
    Molecular Mycobacteriology, Research Center Borstel, Borstel, Germany
    PLoS ONE 7:e39855. 2012
    ..High throughput assays can be established which will be needed for large association studies that are mandatory for detailed investigation of host-pathogen-interaction during TB infection...
  9. ncbi request reprint Phylogenetic polymorphisms in antibiotic resistance genes of the Mycobacterium tuberculosis complex
    Silke Feuerriegel
    Molecular Mycobacteriology, Borstel, Germany
    J Antimicrob Chemother 69:1205-10. 2014
    ..In this context, it is particularly important to distinguish phylogenetically informative neutral polymorphisms from true resistance-conferring mutations...