Ursula Rescher

Summary

Country: Germany

Publications

  1. ncbi S100A10/p11: family, friends and functions
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, Von Esmarch Str 56, 48149 Muenster, Germany
    Pflugers Arch 455:575-82. 2008
  2. ncbi Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, 48149 Muenster, Germany
    J Cell Sci 121:2177-85. 2008
  3. ncbi Annexin A8 regulates late endosome organization and function
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, 48149 Muenster, Germany
    Mol Biol Cell 19:5267-78. 2008
  4. ncbi Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes
    Ursula Rescher
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, Munster 48149, Germany
    J Cell Sci 117:3473-80. 2004
  5. ncbi Annexin A8 displays unique phospholipid and F-actin binding properties
    Verena Goebeler
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 580:2430-4. 2006
  6. ncbi Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain
    Susanne Radke
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, ZMBE, IZKF Münster, University of Munster, Von Esmarch Str 56, 48149 Munster, Germany
    FEBS Lett 578:95-8. 2004
  7. ncbi Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling
    Danute Pupjalis
    Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, Institute of Medical Biochemistry, University of Muenster, Muenster, Germany
    EMBO Mol Med 3:102-14. 2011
  8. ncbi Annexins--unique membrane binding proteins with diverse functions
    Ursula Rescher
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Cell Sci 117:2631-9. 2004
  9. ncbi TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway
    Stan F J van de Graaf
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Biol Chem 283:4077-86. 2008
  10. ncbi Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25
    Carsten Lange
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, Muenster, Germany
    J Leukoc Biol 82:1592-604. 2007

Collaborators

  • Volker Gerke
  • Alexei Kharitonenkov
  • B Nilius
  • Paul L McNeil
  • Katia Monastyrskaya
  • Olivier Staub
  • Fernando Martin-Belmonte
  • Verena Goebeler
  • Stan F J van de Graaf
  • Nicole Zobiack
  • Danute Pupjalis
  • Julia Goetsch
  • Carsten Lange
  • Anna K McNeil
  • Dagmar Zeuschner
  • Rene J M Bindels
  • Joost G J Hoenderop
  • Daniela Ruhe
  • Matthew J Hayes
  • Susanne Radke
  • Ralf Jacob
  • Diane J Kottas
  • Sjoerd Verkaart
  • Michaela Poeter
  • Diane J Starrett
  • Judith Austermann
  • Nadine Frerker
  • Stephen E Moss
  • Klaus-Peter Zimmer
  • Martin Heine
  • Jürgen Eikemeyer
  • Klaus Peter Zimmer
  • Francoise Russo-Marie
  • Hassan Y Naim
  • Jean Prenen
  • Carsten Ludwig
  • Dennis Lamers
  • Dimitra Gkika
  • Sven Laarmann
  • Silke Michgehl
  • M Alexander Schmidt

Detail Information

Publications20

  1. ncbi S100A10/p11: family, friends and functions
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, Von Esmarch Str 56, 48149 Muenster, Germany
    Pflugers Arch 455:575-82. 2008
    ..Based on these data, we propose that S100A10 functions as a linker tethering certain transmembrane proteins to annexin A2 thereby assisting their traffic to the plasma membrane and/or their firm anchorage at certain membrane sites...
  2. ncbi Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, 48149 Muenster, Germany
    J Cell Sci 121:2177-85. 2008
    ..Thus, a tyrosine phosphorylation switch in annexin A2 is an important event in triggering Rho/ROCK-dependent and actin-mediated changes in cell morphology associated with the control of cell adhesion...
  3. ncbi Annexin A8 regulates late endosome organization and function
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, 48149 Muenster, Germany
    Mol Biol Cell 19:5267-78. 2008
    ....
  4. ncbi Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes
    Ursula Rescher
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, Munster 48149, Germany
    J Cell Sci 117:3473-80. 2004
    ..Thus, the direct interaction of annexin 2 with PtdIns(4,5)P(2) is a means of specifically recruiting the annexin 2-p11 complex to sites of membrane-associated actin assembly...
  5. ncbi Annexin A8 displays unique phospholipid and F-actin binding properties
    Verena Goebeler
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 580:2430-4. 2006
    ..These properties suggest a role of annexin A8 in the organization of certain actin-associated membrane domains...
  6. ncbi Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain
    Susanne Radke
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, ZMBE, IZKF Münster, University of Munster, Von Esmarch Str 56, 48149 Munster, Germany
    FEBS Lett 578:95-8. 2004
    ..We found that this interaction was independent of a functional phosphorylation site in the annexin 1 N-terminal domain but mediated through the Ca2+ binding core domain...
  7. ncbi Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling
    Danute Pupjalis
    Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, Institute of Medical Biochemistry, University of Muenster, Muenster, Germany
    EMBO Mol Med 3:102-14. 2011
    ..This identifies annexin A1 as part of the anti-inflammatory pattern of apoptotic cells and links the activation of FPRs to established signalling pathways triggering anti-inflammatory responses...
  8. ncbi Annexins--unique membrane binding proteins with diverse functions
    Ursula Rescher
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Cell Sci 117:2631-9. 2004
    ..Among other things, this is evident in annexin A1- and A2-knockout mice, which show impaired regulation of neutrophil extravasation and defects in plasmin generation, respectively...
  9. ncbi TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway
    Stan F J van de Graaf
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Biol Chem 283:4077-86. 2008
    ..Furthermore, the endocytic recycling kinetics is decreased upon treatment with Ca(2+) chelator BAPTA-AM, indicating that the channel's trafficking pathways are dynamically controlled by Ca(2+)...
  10. ncbi Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25
    Carsten Lange
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, Muenster, Germany
    J Leukoc Biol 82:1592-604. 2007
    ..This identifies the annexin A1 N-terminal peptide as a stimulus, eliciting not only short-term, post-translational effects in human monocytes but also transcriptional changes, defining a more anti-inflammatory profile...
  11. ncbi Atypical properties displayed by annexin A9, a novel member of the annexin family of Ca(2+) and lipid binding proteins
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 546:359-64. 2003
    ..These results indicate that annexin A9 is a unique member of the annexin family whose intracellular activity is not subject to Ca(2+) regulation...
  12. ncbi PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
    Fernando Martin-Belmonte
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Cell 128:383-97. 2007
    ..Loss of function of PTEN, Anx2, Cdc42, or aPKC prevents normal development of the apical surface and lumen. We conclude that the mechanism of PTEN, PtdIns(4,5)P2, Anx2, Cdc42, and aPKC controls apical plasma membrane and lumen formation...
  13. ncbi Requirement for annexin A1 in plasma membrane repair
    Anna K McNeil
    Department of Cellular Biology and Anatomy, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA
    J Biol Chem 281:35202-7. 2006
    ..We propose that Ca2+ entering through a disruption locally induces annexin A1 binding to membranes, initiating emergency fusion events whenever and wherever required...
  14. ncbi Annexins as intracellular calcium sensors
    Katia Monastyrskaya
    Department of Cell Biology, Institute of Anatomy, University of Bern, 3000 Bern 9, Switzerland
    Cell Calcium 41:207-19. 2007
    ..Given the fact that several annexins are present within any one cell, it is likely that they form a sophisticated [Ca(2+)] sensing system, with a regulatory influence on other signaling pathways...
  15. ncbi Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2
    Nicole Zobiack
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von-Esmarch-Str. 56, , Germany
    J Cell Sci 115:91-8. 2002
    ....
  16. ncbi Proteolytic cleavage of annexin 1 by human leukocyte elastase
    Ursula Rescher
    Center for Molecular Biology of Inflammation, Institute for Medical Biochemistry, Von Esmarch Strasse 56, 48149 Munster, Germany
    Biochim Biophys Acta 1763:1320-4. 2006
    ..The identification of annexin 1 as a substrate for HLE supports the model in which annexin 1 participates in regulating leukocyte emigration into inflamed tissue through N-terminal peptides generated at inflammatory sites...
  17. ncbi Annexin-actin interactions
    Matthew J Hayes
    Division of Cell Biology, Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK
    Traffic 5:571-6. 2004
    ..In this review we discuss the current state of knowledge on this topic, and consider how and where annexins may fit into the complex molecular machinery that regulates the actin cytoskeleton...
  18. ncbi Annexin II is required for apical transport in polarized epithelial cells
    Ralf Jacob
    Department of Physiological Chemistry, School of Veterinary Medicine Hannover, Germany
    J Biol Chem 279:3680-4. 2004
    ..The annexin II-S100A10 complex plays therefore a crucial role in routing SAVs to the apical membrane of epithelial cells...
  19. ncbi The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes
    Nicole Zobiack
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, D 48149 Munster, Germany
    Mol Biol Cell 14:4896-908. 2003
    ....
  20. ncbi Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex
    Stan F J van de Graaf
    Department of Cell Physiology, Nijmegen Center for Molecular Life Sciences, University Medical Center Nijmegen, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    EMBO J 22:1478-87. 2003
    ..In conclusion, the S100A10-annexin 2 complex plays a crucial role in routing of TRPV5 and TRPV6 to plasma membrane...