Ursula Rescher

Summary

Country: Germany

Publications

  1. pmc Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling
    Danute Pupjalis
    Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, Institute of Medical Biochemistry, University of Muenster, Muenster, Germany
    EMBO Mol Med 3:102-14. 2011
  2. ncbi request reprint S100A10/p11: family, friends and functions
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, Von Esmarch Str 56, 48149 Muenster, Germany
    Pflugers Arch 455:575-82. 2008
  3. ncbi request reprint Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, 48149 Muenster, Germany
    J Cell Sci 121:2177-85. 2008
  4. doi request reprint Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling
    Michaela Poeter
    University of Munster, Munster, Germany
    Biochim Biophys Acta 1833:1700-11. 2013
  5. pmc Annexin A8 regulates late endosome organization and function
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, 48149 Muenster, Germany
    Mol Biol Cell 19:5267-78. 2008
  6. ncbi request reprint Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes
    Ursula Rescher
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, Munster 48149, Germany
    J Cell Sci 117:3473-80. 2004
  7. ncbi request reprint Annexin A8 displays unique phospholipid and F-actin binding properties
    Verena Goebeler
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 580:2430-4. 2006
  8. ncbi request reprint Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain
    Susanne Radke
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, ZMBE, IZKF Münster, University of Munster, Von Esmarch Str 56, 48149 Munster, Germany
    FEBS Lett 578:95-8. 2004
  9. pmc The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells
    Thorsten Eierhoff
    Institute of Molecular Virology, ZMBE, Westfalische Wilhelms University, Munster, Germany
    PLoS Pathog 6:e1001099. 2010
  10. ncbi request reprint Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2
    Nicole Zobiack
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, D 48149 Munster, Germany
    J Cell Sci 115:91-8. 2002

Collaborators

Detail Information

Publications26

  1. pmc Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling
    Danute Pupjalis
    Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, Institute of Medical Biochemistry, University of Muenster, Muenster, Germany
    EMBO Mol Med 3:102-14. 2011
    ..This identifies annexin A1 as part of the anti-inflammatory pattern of apoptotic cells and links the activation of FPRs to established signalling pathways triggering anti-inflammatory responses...
  2. ncbi request reprint S100A10/p11: family, friends and functions
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, Von Esmarch Str 56, 48149 Muenster, Germany
    Pflugers Arch 455:575-82. 2008
    ..Based on these data, we propose that S100A10 functions as a linker tethering certain transmembrane proteins to annexin A2 thereby assisting their traffic to the plasma membrane and/or their firm anchorage at certain membrane sites...
  3. ncbi request reprint Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion
    Ursula Rescher
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, 48149 Muenster, Germany
    J Cell Sci 121:2177-85. 2008
    ..Thus, a tyrosine phosphorylation switch in annexin A2 is an important event in triggering Rho/ROCK-dependent and actin-mediated changes in cell morphology associated with the control of cell adhesion...
  4. doi request reprint Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling
    Michaela Poeter
    University of Munster, Munster, Germany
    Biochim Biophys Acta 1833:1700-11. 2013
    ..This article is part of a Special Issue entitled: 12th European Symposium on Calcium...
  5. pmc Annexin A8 regulates late endosome organization and function
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, 48149 Muenster, Germany
    Mol Biol Cell 19:5267-78. 2008
    ....
  6. ncbi request reprint Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes
    Ursula Rescher
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, Munster 48149, Germany
    J Cell Sci 117:3473-80. 2004
    ..Thus, the direct interaction of annexin 2 with PtdIns(4,5)P(2) is a means of specifically recruiting the annexin 2-p11 complex to sites of membrane-associated actin assembly...
  7. ncbi request reprint Annexin A8 displays unique phospholipid and F-actin binding properties
    Verena Goebeler
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 580:2430-4. 2006
    ..These properties suggest a role of annexin A8 in the organization of certain actin-associated membrane domains...
  8. ncbi request reprint Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain
    Susanne Radke
    Institute for Medical Biochemistry, Centre for Molecular Biology of Inflammation, ZMBE, IZKF Münster, University of Munster, Von Esmarch Str 56, 48149 Munster, Germany
    FEBS Lett 578:95-8. 2004
    ..We found that this interaction was independent of a functional phosphorylation site in the annexin 1 N-terminal domain but mediated through the Ca2+ binding core domain...
  9. pmc The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells
    Thorsten Eierhoff
    Institute of Molecular Virology, ZMBE, Westfalische Wilhelms University, Munster, Germany
    PLoS Pathog 6:e1001099. 2010
    ....
  10. ncbi request reprint Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2
    Nicole Zobiack
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, Von Esmarch Str 56, D 48149 Munster, Germany
    J Cell Sci 115:91-8. 2002
    ....
  11. doi request reprint The tumor suppressor annexin A10 is a novel component of nuclear paraspeckles
    Nina Quiskamp
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Munster, 48149, Munster, Germany
    Cell Mol Life Sci 71:311-29. 2014
    ..The identification of unique nuclear and biochemical characteristics of annexin A10 points towards its membrane-independent role in paraspeckle-associated mRNA regulation or processing...
  12. ncbi request reprint Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25
    Carsten Lange
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Centre, University of Muenster, Muenster, Germany
    J Leukoc Biol 82:1592-604. 2007
    ..This identifies the annexin A1 N-terminal peptide as a stimulus, eliciting not only short-term, post-translational effects in human monocytes but also transcriptional changes, defining a more anti-inflammatory profile...
  13. ncbi request reprint Annexins--unique membrane binding proteins with diverse functions
    Ursula Rescher
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Cell Sci 117:2631-9. 2004
    ..Among other things, this is evident in annexin A1- and A2-knockout mice, which show impaired regulation of neutrophil extravasation and defects in plasmin generation, respectively...
  14. pmc Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation
    Agnes Musiol
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation and Interdisciplinary Clinical Research Centre, University of Munster, Munster, Germany
    MBio 4:e00608-13. 2013
    ..Our results show that IAV replication depends on maintenance of the cellular cholesterol balance and identify AnxA6 as a critical factor in linking IAV to cellular cholesterol homeostasis...
  15. ncbi request reprint Atypical properties displayed by annexin A9, a novel member of the annexin family of Ca(2+) and lipid binding proteins
    Verena Goebeler
    Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Munster, Von Esmarch Str 56, D 48149 Munster, Germany
    FEBS Lett 546:359-64. 2003
    ..These results indicate that annexin A9 is a unique member of the annexin family whose intracellular activity is not subject to Ca(2+) regulation...
  16. ncbi request reprint TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway
    Stan F J van de Graaf
    Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Munster, Von Esmarch Strasse 56, Munster 48149, Germany
    J Biol Chem 283:4077-86. 2008
    ..Furthermore, the endocytic recycling kinetics is decreased upon treatment with Ca(2+) chelator BAPTA-AM, indicating that the channel's trafficking pathways are dynamically controlled by Ca(2+)...
  17. ncbi request reprint Functional activation of the formyl peptide receptor by a new endogenous ligand in human lung A549 cells
    Ursula Rescher
    Center for Molecular Biology of Inflammation, Institute for Medical Biochemistry, Munster, Germany
    J Immunol 169:1500-4. 2002
    ..Hence, activation of nonmyeloid FPR by its endogenous ligand annexin 1 could participate in the regulation of acute-phase responses, e.g., during inflammation and/or wound healing...
  18. doi request reprint Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism
    Sherif A Ibrahim
    Department of Gynecology and Obstetrics, Munster University Hospital, Munster, Germany
    Int J Cancer 131:E884-96. 2012
    ....
  19. pmc PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
    Fernando Martin-Belmonte
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Cell 128:383-97. 2007
    ..Loss of function of PTEN, Anx2, Cdc42, or aPKC prevents normal development of the apical surface and lumen. We conclude that the mechanism of PTEN, PtdIns(4,5)P2, Anx2, Cdc42, and aPKC controls apical plasma membrane and lumen formation...
  20. ncbi request reprint Requirement for annexin A1 in plasma membrane repair
    Anna K McNeil
    Department of Cellular Biology and Anatomy, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA
    J Biol Chem 281:35202-7. 2006
    ..We propose that Ca2+ entering through a disruption locally induces annexin A1 binding to membranes, initiating emergency fusion events whenever and wherever required...
  21. ncbi request reprint Annexins as intracellular calcium sensors
    Katia Monastyrskaya
    Department of Cell Biology, Institute of Anatomy, University of Bern, 3000 Bern 9, Switzerland
    Cell Calcium 41:207-19. 2007
    ..Given the fact that several annexins are present within any one cell, it is likely that they form a sophisticated [Ca(2+)] sensing system, with a regulatory influence on other signaling pathways...
  22. pmc Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex
    Stan F J van de Graaf
    Department of Cell Physiology, Nijmegen Center for Molecular Life Sciences, University Medical Center Nijmegen, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    EMBO J 22:1478-87. 2003
    ..In conclusion, the S100A10-annexin 2 complex plays a crucial role in routing of TRPV5 and TRPV6 to plasma membrane...
  23. pmc The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes
    Nicole Zobiack
    Institute for Medical Biochemistry, Center for Molecular Biology of Inflammation, D 48149 Munster, Germany
    Mol Biol Cell 14:4896-908. 2003
    ....
  24. ncbi request reprint Annexin II is required for apical transport in polarized epithelial cells
    Ralf Jacob
    Department of Physiological Chemistry, School of Veterinary Medicine Hannover, Germany
    J Biol Chem 279:3680-4. 2004
    ..The annexin II-S100A10 complex plays therefore a crucial role in routing SAVs to the apical membrane of epithelial cells...
  25. ncbi request reprint Annexin-actin interactions
    Matthew J Hayes
    Division of Cell Biology, Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Traffic 5:571-6. 2004
    ..In this review we discuss the current state of knowledge on this topic, and consider how and where annexins may fit into the complex molecular machinery that regulates the actin cytoskeleton...
  26. ncbi request reprint Proteolytic cleavage of annexin 1 by human leukocyte elastase
    Ursula Rescher
    Center for Molecular Biology of Inflammation, Institute for Medical Biochemistry, Von Esmarch Strasse 56, 48149 Munster, Germany
    Biochim Biophys Acta 1763:1320-4. 2006
    ..The identification of annexin 1 as a substrate for HLE supports the model in which annexin 1 participates in regulating leukocyte emigration into inflamed tissue through N-terminal peptides generated at inflammatory sites...