Daniel Razansky

Summary

Country: Germany

Publications

  1. ncbi request reprint Polarization-sensitive optoacoustic tomography of optically diffuse tissues
    Daniel Razansky
    Institute for Biological and Medical Imaging, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Opt Lett 33:2308-10. 2008
  2. ncbi request reprint Sensitivity of molecular target detection by multispectral optoacoustic tomography (MSOT)
    Daniel Razansky
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Med Phys 36:939-45. 2009
  3. doi request reprint Optical imaging of cancer heterogeneity with multispectral optoacoustic tomography
    Eva Herzog
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Neuherberg, Germany
    Radiology 263:461-8. 2012
  4. ncbi request reprint Model-based optoacoustic inversions with incomplete projection data
    Andreas Buehler
    Institute for Biological and Medical Imaging, Technische Universität München und Helmholtz Zentrum München, Ingoldstädter Landstrafsse 1, D 85764 Neuherberg, Germany
    Med Phys 38:1694-704. 2011
  5. doi request reprint Weighted model-based optoacoustic reconstruction in acoustic scattering media
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstraße 1, D 85764 Neuherberg, Germany
    Phys Med Biol 58:5555-66. 2013
  6. doi request reprint Multispectral opto-acoustic tomography (MSOT) of the brain and glioblastoma characterization
    Neal C Burton
    Institute for Biological and Medical Imaging, Helmholtz Center Munich, Neuherberg, Germany
    Neuroimage 65:522-8. 2013
  7. doi request reprint Accurate model-based reconstruction algorithm for three-dimensional optoacoustic tomography
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    IEEE Trans Med Imaging 31:1922-8. 2012
  8. ncbi request reprint Fast semi-analytical model-based acoustic inversion for quantitative optoacoustic tomography
    Amir Rosenthal
    Institute for Biological and Medical Imaging, and Chair for Biological Imaging, Technische Universität of München and Helmholtz Zentrum München, 85764 Neuherberg, Germany
    IEEE Trans Med Imaging 29:1275-85. 2010
  9. ncbi request reprint Modeling the shape of cylindrically focused transducers in three-dimensional optoacoustic tomography
    Daniel Queirós
    Institute for Biological and Medical Imaging IBMI, Helmholtz Zentrum Munchen, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    J Biomed Opt 18:076014. 2013
  10. doi request reprint Non-invasive whole-body imaging of adult zebrafish with optoacoustic tomography
    Rui Ma
    Technical University of Munich, Ingolstädter Landstraße 1, Neuherberg, Germany
    Phys Med Biol 57:7227-37. 2012

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Polarization-sensitive optoacoustic tomography of optically diffuse tissues
    Daniel Razansky
    Institute for Biological and Medical Imaging, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Opt Lett 33:2308-10. 2008
    ..The technique is expected to enable highly accurate imaging of polarization contrast in tissues, far beyond the current capabilities of pure optical polarization-imaging approaches...
  2. ncbi request reprint Sensitivity of molecular target detection by multispectral optoacoustic tomography (MSOT)
    Daniel Razansky
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Med Phys 36:939-45. 2009
    ..The theoretical predictions are further validated in phantom experiments involving Cy5.5, a common near-infrared fluorescent molecular agent...
  3. doi request reprint Optical imaging of cancer heterogeneity with multispectral optoacoustic tomography
    Eva Herzog
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Neuherberg, Germany
    Radiology 263:461-8. 2012
    ..To investigate whether multispectral optoacoustic tomography (MSOT) can reveal the heterogeneous distributions of exogenous agents of interest and vascular characteristics through tumors of several millimeters in diameter in vivo...
  4. ncbi request reprint Model-based optoacoustic inversions with incomplete projection data
    Andreas Buehler
    Institute for Biological and Medical Imaging, Technische Universität München und Helmholtz Zentrum München, Ingoldstädter Landstrafsse 1, D 85764 Neuherberg, Germany
    Med Phys 38:1694-704. 2011
    ..In many tomographic imaging scenarios, however, only limited-view or partial projection data are available, which has been shown to generate image artifacts and overall loss of quantification accuracy...
  5. doi request reprint Weighted model-based optoacoustic reconstruction in acoustic scattering media
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstraße 1, D 85764 Neuherberg, Germany
    Phys Med Biol 58:5555-66. 2013
    ..The statistically-based weighting is subsequently verified experimentally, attaining quality improvement of the optoacoustic image reconstructions in the presence of acoustic mismatches in tissue phantoms and small animals ex-vivo. ..
  6. doi request reprint Multispectral opto-acoustic tomography (MSOT) of the brain and glioblastoma characterization
    Neal C Burton
    Institute for Biological and Medical Imaging, Helmholtz Center Munich, Neuherberg, Germany
    Neuroimage 65:522-8. 2013
    ..We also demonstrate how MSOT offers several compelling features for brain research and allows time-dependent detection and quantification of brain parameters that are not available using other imaging methods without invasive procedures...
  7. doi request reprint Accurate model-based reconstruction algorithm for three-dimensional optoacoustic tomography
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    IEEE Trans Med Imaging 31:1922-8. 2012
    ..Superior performance versus commonly-used backprojection inversion algorithms is showcased by numerical simulations and phantom experiments...
  8. ncbi request reprint Fast semi-analytical model-based acoustic inversion for quantitative optoacoustic tomography
    Amir Rosenthal
    Institute for Biological and Medical Imaging, and Chair for Biological Imaging, Technische Universität of München and Helmholtz Zentrum München, 85764 Neuherberg, Germany
    IEEE Trans Med Imaging 29:1275-85. 2010
    ....
  9. ncbi request reprint Modeling the shape of cylindrically focused transducers in three-dimensional optoacoustic tomography
    Daniel Queirós
    Institute for Biological and Medical Imaging IBMI, Helmholtz Zentrum Munchen, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    J Biomed Opt 18:076014. 2013
    ..Improvements of the results rendered with the introduced reconstruction procedure as compared with the 2-D-based approach are described and discussed for simulations and experiments with phantoms and biological tissues...
  10. doi request reprint Non-invasive whole-body imaging of adult zebrafish with optoacoustic tomography
    Rui Ma
    Technical University of Munich, Ingolstädter Landstraße 1, Neuherberg, Germany
    Phys Med Biol 57:7227-37. 2012
    ....
  11. pmc Fast multispectral optoacoustic tomography (MSOT) for dynamic imaging of pharmacokinetics and biodistribution in multiple organs
    Adrian Taruttis
    Institute for Biological and Medical Imaging, Helmholtz Zentrum Munich, Technical University Munich, Munich, Germany
    PLoS ONE 7:e30491. 2012
    ..Overall, such imaging performance introduces previously undocumented capabilities of fast, high resolution in vivo imaging of the fate of optical agents for drug discovery and basic biological research...
  12. doi request reprint Multispectral optoacoustic tomography by means of normalized spectral ratio
    Thomas Jetzfellner
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Ingolstaedter Landstr 1, 85764 Neuherberg, Germany
    Opt Lett 36:4176-8. 2011
    ..Herein we introduce a spectral ratio approach that accounts for photon fluence variations. The performance and imaging improvement achieved with the proposed method is showcased both numerically and experimentally in phantoms and mice...
  13. doi request reprint Optoacoustic tomography with varying illumination and non-uniform detection patterns
    Thomas Jetzfellner
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Ingolstaedter Landstr 1, 85764 Neuherberg, Germany
    J Opt Soc Am A Opt Image Sci Vis 27:2488-95. 2010
    ..Significant improvements in image fidelity and quantification are showcased both numerically and experimentally on tissue phantoms and mice...
  14. doi request reprint The effects of acoustic attenuation in optoacoustic signals
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    Phys Med Biol 56:6129-48. 2011
    ..The validity and benefits of the suggested modelling and correction approaches are experimentally validated in phantom measurements...
  15. doi request reprint Wideband optical sensing using pulse interferometry
    Amir Rosenthal
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    Opt Express 20:19016-29. 2012
    ..The achieved sensitivity is equivalent to the theoretical limit of a 6 MHz narrow-line width laser, which is 40 times higher than what can be usually achieved by incoherent interferometry for the same optical resonator...
  16. doi request reprint Efficient framework for model-based tomographic image reconstruction using wavelet packets
    Amir Rosenthal
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    IEEE Trans Med Imaging 31:1346-57. 2012
    ..The performance of the new methodology is demonstrated for the case of 2-D optoacoustic tomography for both numerically generated and experimental data...
  17. doi request reprint Acceleration of optoacoustic model-based reconstruction using angular image discretization
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    IEEE Trans Med Imaging 31:1154-62. 2012
    ..It is further anticipated that the new approach will greatly facilitate development of high performance 3-D optoacoustic reconstruction methods...
  18. doi request reprint Motion clustering for deblurring multispectral optoacoustic tomography images of the mouse heart
    Adrian Taruttis
    Helmholtz Zentrum München and Technische Universtität München, Institute for Biological and Medical Imaging, 85764 Neuherberg, Germany
    J Biomed Opt 17:016009. 2012
    ..The correction method presented could be generally applied to other MSOT imaging applications prone to motion artifacts, for example, by respiration and heartbeat...
  19. doi request reprint Near-field thermoacoustic imaging with transmission line pulsers
    Murad Omar
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Ingolstädter Landstr 1, Neuherberg, Germany
    Med Phys 39:4460-6. 2012
    ..This work aimed at investigating transmission lines as a method to generate excitation pulses to improve the NRT resolution over previous implementations without compromising the energy coupled into tissue...
  20. ncbi request reprint Model-based optoacoustic inversion with arbitrary-shape detectors
    Amir Rosenthal
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, 85764 Neuherberg, Germany
    Med Phys 38:4285-95. 2011
    ..This effect may lead to attenuation or distortion in the recorded signal and, consequently, in the reconstructed image...
  21. doi request reprint Statistical approach for optoacoustic image reconstruction in the presence of strong acoustic heterogeneities
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich, Neuherberg, Germany
    IEEE Trans Med Imaging 30:401-8. 2011
    ..This performance is directly related to in vivo small animal imaging applications involving imaging in the presence of bones, lungs, and other highly mismatched organs...
  22. doi request reprint Blind source unmixing in multi-spectral optoacoustic tomography
    Jürgen Glatz
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany
    Opt Express 19:3175-84. 2011
    ..We further demonstrate its capacity with temporal unmixing on real-time MSOT data obtained in-vivo for enhancing the visualization of absorber agent flow in the mouse vascular system...
  23. doi request reprint Volumetric real-time multispectral optoacoustic tomography of biomarkers
    Daniel Razansky
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Neuherberg, Germany
    Nat Protoc 6:1121-9. 2011
    ..Overall, the entire protocol can be completed within 15-30 min for acquisition of a whole-body multispectral data set from a living mouse...
  24. doi request reprint Video rate optoacoustic tomography of mouse kidney perfusion
    Andreas Buehler
    Institute for Biological and Medical Imaging, Technische Universität München und Helmholtz Zentrum München, Ingoldstädter Landstrasse 1, 85764 Neuherberg, Germany
    Opt Lett 35:2475-7. 2010
    ..The previously undocumented capacity of whole-body optoacoustic tomography at a video rate has been demonstrated by visualizing mouse kidney perfusion using Indocyanine Green in vivo...
  25. doi request reprint Optoacoustic methods for frequency calibration of ultrasonic sensors
    Amir Rosenthal
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    IEEE Trans Ultrason Ferroelectr Freq Control 58:316-26. 2011
    ..The methods are successfully confirmed experimentally by measuring the frequency response of a common piezoelectric detector having a cylindrically focused shape...
  26. doi request reprint Optical and opto-acoustic imaging
    Vasilis Ntziachristos
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany
    Recent Results Cancer Res 187:133-50. 2013
    ..These new-found imaging abilities directly relate to preclinical screening applications in animal models and are foreseen to significantly impact clinical decision making as well...
  27. doi request reprint Artefact reduction in optoacoustic tomographic imaging by estimating the distribution of acoustic scatterers
    X Luís Dean-Ben
    Technical University of Munich and Helmholtz Center Munich, Institute for Biological and Medical Imaging, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    J Biomed Opt 17:110504. 2012
    ..Experimental results in a tissue-mimicking phantom clearly demonstrate improved performance as compared to the case in which no information on the distribution of acoustic scatterers is available...
  28. doi request reprint Spatial characterization of the response of a silica optical fiber to wideband ultrasound
    Amir Rosenthal
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Neuherberg, Germany
    Opt Lett 37:3174-6. 2012
    ..This property reveals new possibilities for high-performance imaging using fiber-based ultrasound sensors, where knowledge of the sensor's spatial sensitivity map is generally required...
  29. ncbi request reprint Near-field radiofrequency thermoacoustic tomography with impulse excitation
    Daniel Razansky
    Institute for Biological and Medical Imaging IBMI, Technische Universität München and Helmholtz Zentrum München, Ingolstaedter Landstr 1, D 85764 Neuherberg, Germany
    Med Phys 37:4602-7. 2010
    ..However, existing implementations are based on modulated-carrier-frequency amplification solutions, which are generally costly and cannot achieve ultrahigh-peak-power requirements essential for optimal thermoacoustic signal generation...
  30. doi request reprint Near-field thermoacoustic tomography of small animals
    Stephan Kellnberger
    Institute for Biological and Medical Imaging IBMI, Technische Universität München and Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Phys Med Biol 56:3433-44. 2011
    ..The best spatial resolution achieved for those experiments was 150 µm...
  31. doi request reprint Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging
    Rui Ma
    Institute for Biological and Medical Imaging, Technical University of Munich, Neuherberg, Germany
    Opt Express 17:21414-26. 2009
    ..The system performance is determined in phantom experiments involving molecular probes and validated by imaging of small animals of various scales...
  32. doi request reprint Real-time imaging of cardiovascular dynamics and circulating gold nanorods with multispectral optoacoustic tomography
    Adrian Taruttis
    Institute for Biological and Medical Imaging, Technical University of Munich, Neuherberg, Germany
    Opt Express 18:19592-602. 2010
    ..We discuss the potential of this imaging ability in cardiovascular disease (CVD) research and clinical applications...
  33. doi request reprint Model-based optoacoustic imaging using focused detector scanning
    Miguel Ángel Araque Caballero
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Ingoldstädter Landstrasse 1, Neuherberg 85764, Germany
    Opt Lett 37:4080-2. 2012
    ..The proposed method shows superior imaging performance over previously considered techniques...
  34. pmc High resolution tumor targeting in living mice by means of multispectral optoacoustic tomography
    Andreas Buehler
    Institute for Biological and Medical Imaging, Technische Universität München und Helmholtz Zentrum München, Ingoldstädter Landstraße 1, Neuherberg 85764, Germany
    EJNMMI Res 2:14. 2012
    ..abstract:..
  35. pmc Multispectral optoacoustic tomography of matrix metalloproteinase activity in vulnerable human carotid plaques
    Daniel Razansky
    Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany
    Mol Imaging Biol 14:277-85. 2012
    ..This study is aimed at demonstrating a new method with high potential for noninvasive clinical cardiovascular diagnostics of vulnerable plaques using high-resolution deep-tissue multispectral optoacoustic tomography (MSOT) technology...
  36. doi request reprint Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo
    R Nika Razansky
    Biological Imaging, Technische Universität München and Institute for Biological and Medical Imaging, IBMI, Helmholtz Zentrum Munchen, Munich, Germany
    Opt Express 18:11372-81. 2010
    ..This imaging approach is geared toward in vivo molecular imaging of atherosclerotic biomarkers and is engineered to allow seamless integration into the cardiac catheterization laboratory...
  37. ncbi request reprint Effects of small variations of speed of sound in optoacoustic tomographic imaging
    X Luís Dean-Ben
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    Med Phys 41:073301. 2014
    ..In this work, the authors investigate the effects of acoustic heterogeneities and discuss potential benefits of accounting for those during the reconstruction procedure...
  38. pmc Fast scanning coaxial optoacoustic microscopy
    Rui Ma
    Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany
    Biomed Opt Express 3:1724-31. 2012
    ..System performance is showcased in phantoms and in vivo imaging of microvasculature, achieving real time operation in two dimensions and penetration of 6 mm into optically dense human tissues...
  39. doi request reprint High-sensitivity compact ultrasonic detector based on a pi-phase-shifted fiber Bragg grating
    Amir Rosenthal
    Institute for Biological and Medical Imaging IBMI, Technical University of Munich and Helmholtz Center Munich, Ingoldstädter Landstrasse 1, 85764 Neuherberg, Germany
    Opt Lett 36:1833-5. 2011
    ..This performance makes our design attractive for medical imaging applications, such as optoacoustic tomography, in which compact, sensitive, and wideband acoustic detectors are required...
  40. doi request reprint Quantitative optoacoustic signal extraction using sparse signal representation
    Amir Rosenthal
    Institute for Biological and Medical Imaging, Helmholtz Center Munich and Technical University of Munich, Neuherberg, D 85764, Germany
    IEEE Trans Med Imaging 28:1997-2006. 2009
    ....
  41. pmc Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging
    Sonu Bhaskar
    Comprehensive Pneumology Centre, Institute of Lung Biology and Disease, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Part Fibre Toxicol 7:3. 2010
    ....
  42. doi request reprint Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography
    Daniel Razansky
    Institute for Biological and Medical Imaging, Helmholtz Zentrum Munchen, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Phys Med Biol 54:2769-77. 2009
    ..The utility of the method is demonstrated on several whole-body models and small-animal extremities...