Research Topics
Species | Christian PutensenSummaryCountry: Germany Publications
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Publications
Meta-analysis: ventilation strategies and outcomes of the acute respiratory distress syndrome and acute lung injuryChristian Putensen
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
Ann Intern Med 151:566-76. 2009..Trials have provided conflicting results regarding the effect of different ventilatory strategies on the outcomes of patients with the acute respiratory distress syndrome (ARDS) and acute lung injury...
Effects of spontaneous breathing during airway pressure release ventilation on cerebral and spinal cord perfusion in experimental acute lung injuryStefan Kreyer
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
J Neurosurg Anesthesiol 22:323-9. 2010..We investigated the effect of spontaneous breathing on cerebral and spinal blood flow during airway pressure release ventilation (APRV) with and without spontaneous breathing...
Spontaneous breathing with airway pressure release ventilation favors ventilation in dependent lung regions and counters cyclic alveolar collapse in oleic-acid-induced lung injury: a randomized controlled computed tomography trialHermann Wrigge
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Crit Care 9:R780-9. 2005..We hypothesized that spontaneous breathing will result in better ventilation and aeration of dependent lung areas and in less cyclic collapse during the tidal breath...
Effects of spontaneous breathing during airway pressure release ventilation on respiratory work and muscle blood flow in experimental lung injuryRudolf Hering
Department of Anesthesiology and Intensive Care Medicine, Rheinische Friedrich Wilhelms University, Bonn, Germany
Chest 128:2991-8. 2005..To evaluate the effects of spontaneous breathing at ambient airway pressure (Paw) and during airway pressure release ventilation (APRV) on respiratory work and respiratory muscle blood flow (RMBF) in experimental lung injury...
The impact of spontaneous breathing during mechanical ventilationChristian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Curr Opin Crit Care 12:13-8. 2006..This review evaluates the physiological and clinical effects of persisting spontaneous breathing during ventilator support in patients with acute respiratory distress syndrome...
Spontaneous breathing during airway pressure release ventilation in experimental lung injury: effects on hepatic blood flowRudolf Hering
Department of Anaesthesiology and Critical Care Medicine, Bonn University Hospital, Bonn, Germany
Intensive Care Med 34:523-7. 2008..We hypothesized that spontaneous breathing (SB) with airway pressure release ventilation (APRV) provides better systemic and hepatic blood flow than APRV without SB...
Cardiorespiratory effects of spontaneous breathing in two different models of experimental lung injury: a randomized controlled trialDirk Varelmann
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Crit Care 12:R135. 2008..Our objective was to evaluate whether the addition of SB has different effects in two different models of ALI...
Electrical impedance tomography compared with thoracic computed tomography during a slow inflation maneuver in experimental models of lung injuryHermann Wrigge
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Crit Care Med 36:903-9. 2008....
Methodologic aspects of attenuation distributions from static and dynamic thoracic CT techniques in experimental acute lung injuryJörg Zinserling
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, D 53105, Bonn, Germany
Chest 128:2963-70. 2005..We also studied whether a variation in the CT cut level, corresponding to the diaphragm movement over a breath, had any effect on the attenuation distribution...
Effects of spontaneous breathing during airway pressure release ventilation on intestinal blood flow in experimental lung injuryRudolf Hering
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Anesthesiology 99:1137-44. 2003..The authors hypothesized that spontaneous breathing (SB) with airway pressure release ventilation (APRV) provides better systemic and intestinal blood flow than APRV without SB...
[Alveolar ventilation and recruitment under lung protective ventilation]Christian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Anasthesiol Intensivmed Notfallmed Schmerzther 43:770-6; quiz777. 2008..Bedside imaging techniques allowing titration of PEEP or other manoeuvres to prevent end-expiratory alveolar collapse (tidal recruitment) and inspiratory overinflation may be a promising development...
Mechanical ventilation strategies and inflammatory responses to cardiac surgery: a prospective randomized clinical trialHermann Wrigge
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Intensive Care Med 31:1379-87. 2005..To examine whether postoperative mechanical ventilation with lower tidal volumes (V(T)) has protective effects on inflammatory responses induced by cardiopulmonary bypass (CPB) surgery in smokers and nonsmokers...
Proportional assist versus pressure support ventilation in patients with acute respiratory failure: cardiorespiratory responses to artificially increased ventilatory demandDirk Varelmann
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Crit Care Med 33:1968-75. 2005..The latter might be explained by higher peak flows resulting in nonlinearly increased resistive workload that was incompletely compensated by PAV+ATC...
Selective 5-HT(1A)-R-agonist repinotan prevents remifentanil-induced ventilatory depression and prolongs antinociceptionUlf Guenther
Clinic of Anesthesiology and Intensive Care Medicine, Bonn University Hospital, Bonn, Germany
Anesthesiology 116:56-64. 2012....
Assisted breathing is better in acute respiratory failureChristian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Curr Opin Crit Care 11:63-8. 2005..The aim of this paper is to review the role of spontaneous breathing ventilatory modalities with respect to their physiologic or clinical evidence...
The effects of mechanical ventilation on the gut and abdomenChristian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Curr Opin Crit Care 12:160-5. 2006..In the pathogeneses of this syndrome the gastrointestinal tract and liver have received considerable attention...
Tidal recruitment assessed by electrical impedance tomography and computed tomography in a porcine model of lung injury*Thomas Muders
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Crit Care Med 40:903-11. 2012..To determine the validity of electrical impedance tomography to detect and quantify the amount of tidal recruitment caused by different positive end-expiratory pressure levels in a porcine acute lung injury model...
Measurement of functional residual capacity by nitrogen washout during partial ventilatory supportJörg Zinserling
Klinik und Poliklinik fur Anasthesiologie und spezielle Intensivmedizin, Rheinische Friedrich Wilhelms Universitat Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Intensive Care Med 29:720-6. 2003....
Clinical review: biphasic positive airway pressure and airway pressure release ventilationChristian Putensen
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Crit Care 8:492-7. 2004....
Impedance tomography as a new monitoring techniqueThomas Muders
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Curr Opin Crit Care 16:269-75. 2010..Methodological and clinical aspects of EIT when used as a monitoring tool in the intensive care unit are reviewed and discussed...
Spontaneous breathing improves lung aeration in oleic acid-induced lung injuryHermann Wrigge
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Germany
Anesthesiology 99:376-84. 2003..This hypothesis was studied in a porcine model of oleic acid-induced lung injury...
Effects of spontaneous breathing during airway pressure release ventilation on renal perfusion and function in patients with acute lung injuryRudolf Hering
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Intensive Care Med 28:1426-33. 2002....
Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndromeChristof Thees
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, 53105 Bonn, Germany
Crit Care 11:R123. 2007..We hypothesized that cerebral haemodynamics and carbon dioxide reactivity would be impaired in patients with sepsis syndrome and pathological electroencephalogram patterns...
The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivoUlf Guenther
Clinic of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
Anesth Analg 108:1169-76. 2009..Two hypotheses were tested: 1) 8-OH-DPAT at a dose to stimulate spontaneous breathing does not activate nociceptive reflexes. 2) 8-OH-DPAT does not diminish opioid-induced antinociception...
Prone position in mechanically ventilated patients -- the hard or the soft way?Christian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Crit Care 9:253-4. 2005....
Electrical impedance tomography guided ventilation therapyChristian Putensen
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Germany
Curr Opin Crit Care 13:344-50. 2007..Recently, electrical impedance tomography has been introduced as a true bedside technique which provides information on regional ventilation distribution...
Controlled versus assisted mechanical ventilationChristian Putensen
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
Curr Opin Crit Care 8:51-7. 2002..Whereas controlled mechanical ventilation followed by weaning with partial ventilatory support modalities has been the earlier standard in ventilation therapy, this approach should be reconsidered in view of the available data...
The effects of different ventilatory settings on pulmonary and systemic inflammatory responses during major surgeryHermann Wrigge
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Anesth Analg 98:775-81, table of contents. 2004....
Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivorsAlexander Semmler
Department of Neurology, University of Bonn, Bonn, Germany
J Neurol Neurosurg Psychiatry 84:62-9. 2013....
A tumor necrosis factor gene polymorphism influences the inflammatory response after cardiac operationStefan Schroeder
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Ann Thorac Surg 75:534-7. 2003....
Prone positioning, systemic hemodynamics, hepatic indocyanine green kinetics, and gastric intramucosal energy balance in patients with acute lung injuryRudolf Hering
Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Intensive Care Med 28:53-8. 2002..To investigate the effects of prone positioning on systemic hemodynamics, intra-abdominal pressure (IAP), plasma disappearance rate of indocyanine green (PDR(ICG)), and gastric intramucosal to arterial PCO2 difference (Pi-aCO2)...
