C F Poets

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..CONCLUSIONS: Socioeconomic status, obesity, signs of nasal obstruction, and pharyngeal problems were independent risk factors for HS in these primary school children. The expression of HS varied considerably over time...

..Pulse oximeter saturation values are usually obtained by averaging over preceding measurements. This study investigates the dynamics between the averaging time and desaturation level, duration and extent...

..There is an increasing trend towards delivery before 39 weeks of gestational age. The short- and long-term effects of early delivery on the infant have only recently received scientific attention...

..Here, data that support these recent changes in approach will be presented and discussed...

..To identify potential risk factors for unexpected sudden infant deaths (SID) and severe apparent life-threatening events (S-ALTE) within 24 h of birth...

..To review treatments for apnoea of prematurity (AOP)...

..gasping occurred during the majority of SID cases where respiratory patterns have been analysed, but it remains unclear why gasping remains ineffective in resuscitating the infant from hypoxaemia...

..We do not prescribe home monitors for SIDS prevention, but occasionally use pulse oximeters at home for a few weeks if an infant continues to exhibit apnoea of prematurity...

..Apnoea of prematurity has been shown to respond to changes in posture...

..First, however, we need to better define how much AOP can be tolerated in an infant without endangering neurodevelopment...

..To determine the incidence of and possible risk factors for unexpected sudden infant deaths (SID) and severe apparent life-threatening events (S-ALTE) that occurred within 24 hours of birth. This was a monthly epidemiologic survey...

..An improvement of methods to identify the few preterm infants at risk for developing serious consequences of GER is urgently needed...

..It is not known which mode of NCPAP or NIPPV is most effective for AOP...

..Whether withholding or pasteurizing breast milk is warranted, however, depends on long-term outcome...

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..This good performance prompted us to explore our nurses' perceptions of what makes them compliant with alarm limits for pulse oximetry in preterm infants...

..This article reviews recent studies on the relationship between patient volume, level of care, and peri- or neonatal outcome for term and preterm infants...

..Given the above situation, the authors decided to continue breast-feeding of VLBW and ELBW infants in their units after obtaining informed parenteral consent, until data for an evidence-based decision become available...

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..Although perhaps producing the desired therapeutic effect, dexamethasone may do so in newborns at the expense of a near complete paralysis of MPhi-dependent T cell function...

..0-9.8), were independent risk factors for recurrent sleep-related hypoxia. Our data suggest that overweight, passive smoking, respiratory allergies, and acute lung disease may independently contribute to sleep-related hypoxia in children...

..In adult mammals, however, only concentrations of palmitoyl-palmitoleoyl-PC correlate with RR...

..80 versus 0.66. DLWB IL-8 showed a higher sensitivity for EOBI within 6 h after first clinical suspicion than plasma IL-8. It also remained elevated longer. Our results suggest that DLWB IL-8 results in a higher sensitivity for EOBI...

..The aim of this study was to examine neonatal and adult T cell response with respect to the costimulatory MPhi-potential in order to identify molecular predictors for the neonatal immune defense...

..These neonates had more desaturation events while sleeping supine. We speculate, however, that this positional effect likely is too small to affect outcome...

..Several abnormalities may occur in these children, e.g. esophageal atresia (EA), imperforate anus or abdominal wall defects. Correction of EA is often performed as a staged procedure in this group of patients...

..Objective criteria that help to identify those presumably few infants who do require treatment for GER disease are urgently needed...

..Furthermore, the role of frequency of night waking and wake time after sleep onset for daytime functioning was analyzed in the context of total sleep time and sleep onset latency...

..0 +/- 1.2%), and equilibrium was achieved after only 48 hours. We conclude that infusion of deuteriated choline and electrospray ionization tandem mass spectrometry is useful to investigate surfactant metabolism in humans in vivo...

..8% (1.5-4.1%). Clinical and oximetry findings may be helpful for screening and predicting OSA in primary school children...

..Thus, habitual snoring (i.e., snoring frequently or always) was associated with poor academic performance in these primary school children...

..05 versus PBMPhi). IL-10 failed to enhance their ADCC capacity, which was in contrast to PBMPhi (p < 0.05). These data suggest that CBMPhi have an impaired cytotoxic capacity via lower sensitivity toward IL-10...

..These data identify individual surfactant PC species as modifiers of macrophage differentiation and suggest differential effects on innate and adaptive immune functions...

..This variable may predict neurocognitive deficits in school children. Mild hypoxemia, as yet widely considered benign, may already affect cognition in childhood. SpO2..

..Pulmonary interstitial emphysema (PIE) represents a severe complication of respiratory distress syndrome and can dramatically impair the ventilation of premature infants...

..Phenotyping revealed CD14 and CD16 to be down-modulated within minutes. GFP-labeled E. coli may be useful tools to further study MPhi subpopulations and determinants of phagocytosis in cord blood MPhi...

..Caspases CD95L and CD95L mRNA were up-regulated in PBMO. Our results indicate that CBMO are less sensitive toward E. coli-mediated PICD than PBMO. Modifying monocyte apoptosis may be a target for future interventions in sepsis...

..001). Automatic oxygen control may optimize oxygen administration to preterm infants receiving nasal continuous positive airway pressure and reduce nursing time spent with oxygen control...

..Our data suggest a specific defect in CBMO during clearance of apoptotic neutrophils resulting in impaired anti-inflammatory capacity...

..We conclude that pulse rate analysis may be used to detect respiratory events in oximetry recordings in children...

..The optimal rate of enteral feeding (EF) advancement in very low birth weight infants is under debate...

..Thus, their use cannot be generally recommended. The data currently available are not sufficient to give any clearer recommendation on the use of these drugs in infants at high risk of, or established, BPD...

..Acute scrotal discolouration with pain upon palpation in neonates is usually attributed to testicular torsion. The authors report a case where these symptoms had a different cause...

..No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown...

..01). We conclude that blood transfusions significantly reduced heart and respiratory rates in these anemic infants, but had little effect on apnea of prematurity...

..CONCLUSIONS: We suggest that impaired behavior is a key feature of HS independent of intermittent hypoxia and improves when HS ceases...

..Surfactant that is high in PC16:0/14:0 but low in PC16:0/16:0 is compatible with normal respiration and surfactant function in vitro...

..4, 1.4-14.2). Habitual snoring was associated with several sleep problems in our study. Long-term habitual snorers were more likely to have sleep problems than children who had stopped snoring spontaneously...

..We assessed the feasibility of pulse transit time (PTT) in detecting subcortical arousals in eight infants (median age 7 days) suffering from the Pierre Robin sequence and obstructive sleep apnea...

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..Recently, a lethal phenotype characterized by sudden infant death with dysgenesis of the testes syndrome (SIDDT) was identified to be caused by loss of function mutations in the TSPYL1 gene...

..05)), EOBI was most reliably detected by IL-8. CONCLUSION:LBP kinetics were age-dependent. LBP was not sufficiently sensitive in the prediction of EOBI...

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..Here we present a patient treated with this device who showed a decrease in his desaturation index from 50 to < 1...

..To test the hypothesis that a new orthodontic appliance with a velar extension that shifts the tongue anteriorly would reduce upper airway obstruction in infants with Pierre Robin sequence (PRS)...

..We wanted to determine the cognitive and psychosocial outcome of children with PRS treated with a new device aimed at relieving UAO in infancy (pre-epiglottic baton plate)...

..4. This study sample appears to be highly representative with regard to all available data from the population, and therefore suitable to study the prevalence of HS and OSA. Our prevalence estimates are in the range of other studies...

..We hypothesized that neonatal mortality would be higher in small NICUs (< 36 very low birth weight admissions per year) than in large NICUs, with adjustment for volume of the delivery unit...

..There were 72 (range, 40-145) reflux episodes with the esophageal placement and 122 (range, 60-147) during the gastric position (P <.01)...

..CONCLUSION: Bradycardia and desaturation were increased during SSC, even at constant rectal temperature, whereas ET had no effect on these events. Moderate hyperthermia did not increase respiratory instability in preterm infants...

..2-5.1]). CONCLUSION: Despite a significant increase in creatine excretion, suggesting good enteral absorption, CS did not, in the dose and for the duration given in this study, improve symptoms of AOP in these infants...

..24%, P < 0.03) and extended downward more rapidly (12.3 cm/s vs. 5.8 cm/s, P < 0.01). CONCLUSION: Bolus transport of small liquid volumes can be detected via MII...

..A recent study suggested severity of intrauterine growth retardation as a decisive criterion, reporting very poor survival for infants born at </=28 weeks with birth weight <2nd centile...

..However, levels of care are usually not linked to caseload requirements, which remain a point for discussion. We aimed to investigate the impact of annual delivery volume on early neonatal mortality among very preterm births...

..The presented reference values may help clinicians and researchers to improve the interpretation of abbreviated home polysomnography in school-age children...

..We used this technique to investigate whether there is a temporal relationship between GER and AOP and whether GER occurs predominantly before a cardiorespiratory (CR) event...

..These data may serve as a basis for the interpretation of clinical recordings of SpO(2) in children referred for sleep-related breathing disorders...

..79, 0.83, and 0.83 for the three pairs of investigators and 0.84 for the repeated scoring procedure. MII recordings could be analyzed with a high level of inter- and intraobserver agreement...

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