Research Topics
| Dirk GrosenickSummaryAffiliation: Physikalisch-Technische Bundesanstalt Country: Germany Publications
| Collaborators
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Detail Information
Publications
Time-domain optical mammography: initial clinical results on detection and characterization of breast tumorsDirk Grosenick
Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Appl Opt 42:3170-86. 2003..Scatter plots based on a pixelwise analysis of individual mammograms were introduced and applied to represent corelations between characteristic quantities derived from measured distributions of times of flight of photons...
Concentration and oxygen saturation of haemoglobin of 50 breast tumours determined by time-domain optical mammographyDirk Grosenick
Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Phys Med Biol 49:1165-81. 2004..The majority of carcinomas exhibited increased total haemoglobin concentration compared to healthy tissue...
Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patientsDirk Grosenick
Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Phys Med Biol 50:2429-49. 2005....
Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomasDirk Grosenick
Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Phys Med Biol 50:2451-68. 2005..Scatter power of tumours tends to be larger than that of surrounding healthy breast tissue, yet the 95% confidence intervals of both medians overlap...
Scanning time-domain optical mammography: detection and characterization of breast tumors in vivoHerbert Rinneberg
Division of Medical Physics and Metrological Information Technology, Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Technol Cancer Res Treat 4:483-96. 2005..In addition developments on instrumentation and data analysis are covered and possible improvements of optical mammography are briefly discussed...
Evaluation of optical properties of highly scattering media by moments of distributions of times of flight of photonsAdam Liebert
Physikalisch Technische Bundesanstalt, Abbestrasse 2 12, 10587 Berlin, Germany
Appl Opt 42:5785-92. 2003..The moment analysis may serve as a comparatively fast method for evaluating optical properties with sufficient accuracy and can be used, e.g., for on-line monitoring of optical properties of biological tissue...
Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesionsAxel Hagen
Physikalisch Technische Bundesanstalt, Abbestr 2 12, 10587 Berlin, Germany
Opt Express 17:17016-33. 2009..We simulated intravascular and extravascular contributions to ICG tissue concentration contrast within a two-compartment unidirectional pharmacokinetic model...
Fiber dispersion in time domain measurements compromising the accuracy of determination of optical properties of strongly scattering mediaAdam Liebert
Physikalisch Technische Bundesanstalt, Abbestr 2 12, 10587 Berlin, Germany
J Biomed Opt 8:512-6. 2003..The relevance of the investigated dispersion effects is discussed with respect to frequency-domain measurements as well...
Quantification of optical properties of a breast tumor using random walk theoryVictor Chernomordik
National Institutes of Health, National Institute of Child Health and Development, Bethesda, Maryland, USA
J Biomed Opt 7:80-7. 2002..The tumors showed increased absorption and scattering. From the absorption coefficients at both wavelengths blood oxygen saturation was estimated for the tumors and the surrounding tissue...
Reconstruction of optical properties of phantom and breast lesion in vivo from paraxial scanning dataThomas Dierkes
Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 50:2519-42. 2005..Because of the limited angular range sampled by the in vivo and phantom measurements, considerable blurring of the absorption coefficient occurs along the compression direction, compromising longitudinal resolution...
Performance assessment of photon migration instruments: the MEDPHOT protocolAntonio Pifferi
Laboratorio Nazionale per l Ottica Ultra rapida e Ultra intensa, Dipartimento di Fisica e Istituto di Fotonicae Nanotecnologie, Consiglio Nazionale delle Ricerche, Politecnico di Milano, I 20133 Milan, Italy
Appl Opt 44:2104-14. 2005..This protocol was applied to a total of 8 instruments with a set of 32 phantoms, covering a wide range of optical properties...
