Research Topics
Genomes and Genes | Anne Kathrin WermterSummaryAffiliation: Philipps University Country: Germany Publications
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Publications
No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning levelAnne Kathrin Wermter
Clinical Research Group, Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany
Am J Med Genet B Neuropsychiatr Genet 147:535-7. 2008..We conclude that there is no evidence for an involvement of NLGN3 and NLGN4X genetic variants with autism spectrum disorder on high functioning level in our study group...
Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR) in the etiology of autistic disorders on high-functioning levelAnne Kathrin Wermter
Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany
Am J Med Genet B Neuropsychiatr Genet 153:629-39. 2010..In conclusion, our results implicate that genetic variation in the OXTR gene might be relevant in the etiology of autism on high-functioning level...
From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disordersAnne Kathrin Wermter
Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Strasse 6, Marburg, Germany
Eur Child Adolesc Psychiatry 19:199-210. 2010..In future we need larger, sufficiently powered studies that include a detailed and sophisticated characterization of both phenotype and the environmental risk...
Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesityAnke Hinney
Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, D 35039 Marburg, Germany
J Clin Endocrinol Metab 88:4258-67. 2003..8% (P = 0.033; exact one-sided McNemar test). These results support the hypothesis that these MC4R mutations represent major gene effects for obesity...
No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescentsTimo Dirk Müller
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
Mol Genet Metab 90:429-34. 2007..In addition, we confirmed the presence of rs1049353. As these variants could not explain the initial TDT, we conclude that there is no evidence for an association of CNR1 alleles with obesity in our study groups...
Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescentsKatja Holter
Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps University of Marburg, Germany
BMC Med Genet 8:21. 2007..We investigated association of variations in the coding sequence and promoter region of SOCS3 with extreme obesity in German children and adolescents...
Mutation analysis of the MCHR1 gene in human obesityAnne Kathrin Wermter
Clinical Research Group, Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen, University of Duisburg Essen, 45147 Essen, Germany
Eur J Endocrinol 152:851-62. 2005..The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity...
Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humansAnne Kathrin Wermter
Department of Child and Adolescent Psychiatry, University of Marburg, Marburg, Germany
Eur J Hum Genet 16:1126-34. 2008..Analysis of the allelic transmission pattern indicated the existence of polar overdominance, an unusual mode of non-Mendelian inheritance in humans previously known from the callipyge mutation in sheep...
