T Penzel

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Vigilance monitoring--review and practical aspects
    Sebastian Canisius
    Philipps Universitat Marburg, Fachbereich Medizin, Klinik für Innere Medizin mit Schwerpunkt Pneumologie, Marburg, Germany
    Biomed Tech (Berl) 52:77-82. 2007
  2. ncbi request reprint Effect of sleep position and sleep stage on the collapsibility of the upper airways in patients with sleep apnea
    T Penzel
    Department of Medicine, Philipps University, Marburg, Germany
    Sleep 24:90-5. 2001
  3. ncbi request reprint Systematic comparison of different algorithms for apnoea detection based on electrocardiogram recordings
    T Penzel
    Department of Respiratory Critical Care Medicine, Hospital of Philipps University, Marburg, Germany
    Med Biol Eng Comput 40:402-7. 2002
  4. ncbi request reprint Dynamics of heart rate and sleep stages in normals and patients with sleep apnea
    Thomas Penzel
    Division of Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstrasse 1, D 35033 Marburg, Germany
    Neuropsychopharmacology 28:S48-53. 2003
  5. ncbi request reprint Peripheral arterial tonometry for the diagnosis of obstructive sleep apnea
    T Penzel
    Klinik für Innere Medizin Pneumologie, Klinikum, Philipps Universitat, Marburg, Deutschland
    Biomed Tech (Berl) 47:315-7. 2002
  6. ncbi request reprint Prototypes and applications in neurotelemedicine
    T Penzel
    Sleep Laboratory, Department of Internal Medicine, Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Stud Health Technol Inform 78:89-100. 2000
  7. ncbi request reprint Sleep atlas and multimedia database
    T Penzel
    Sleep Laboratory, Department of Internal Medicine, Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Stud Health Technol Inform 78:101-25. 2000
  8. ncbi request reprint Comparison of detrended fluctuation analysis and spectral analysis for heart rate variability in sleep and sleep apnea
    Thomas Penzel
    Division of Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstrasse 1, D 35033 Marburg, Germany
    IEEE Trans Biomed Eng 50:1143-51. 2003
  9. ncbi request reprint A new design of a polysomnography-based multi-center treatment study for the restless legs syndrome
    T Penzel
    Schlafmedizinisches Labor, Klinik für Innere Medizin Pneumologie, Klinikum der Philipps Universität Marburg, Baldingerstrasse 1, D 35033, Marburg, Germany
    Clin Neurophysiol 113:571-8. 2002
  10. ncbi request reprint Peripheral arterial tonometry, oximetry and actigraphy for ambulatory recording of sleep apnea
    Thomas Penzel
    Division for Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Physiol Meas 25:1025-36. 2004

Detail Information

Publications51

  1. ncbi request reprint Vigilance monitoring--review and practical aspects
    Sebastian Canisius
    Philipps Universitat Marburg, Fachbereich Medizin, Klinik für Innere Medizin mit Schwerpunkt Pneumologie, Marburg, Germany
    Biomed Tech (Berl) 52:77-82. 2007
    ....
  2. ncbi request reprint Effect of sleep position and sleep stage on the collapsibility of the upper airways in patients with sleep apnea
    T Penzel
    Department of Medicine, Philipps University, Marburg, Germany
    Sleep 24:90-5. 2001
    ..As a consequence lower nCPAP pressure is needed during lateral positions compared to supine positions...
  3. ncbi request reprint Systematic comparison of different algorithms for apnoea detection based on electrocardiogram recordings
    T Penzel
    Department of Respiratory Critical Care Medicine, Hospital of Philipps University, Marburg, Germany
    Med Biol Eng Comput 40:402-7. 2002
    ..Four of these algorithms achieved perfect scores of 100% in the first part of the study, and two achieved an accuracy of over 90% in the second part of the study...
  4. ncbi request reprint Dynamics of heart rate and sleep stages in normals and patients with sleep apnea
    Thomas Penzel
    Division of Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstrasse 1, D 35033 Marburg, Germany
    Neuropsychopharmacology 28:S48-53. 2003
    ..Heart-rate regulation is part of the autonomous nervous system and sympathetic tone is strongly influenced by the sleep stages...
  5. ncbi request reprint Peripheral arterial tonometry for the diagnosis of obstructive sleep apnea
    T Penzel
    Klinik für Innere Medizin Pneumologie, Klinikum, Philipps Universitat, Marburg, Deutschland
    Biomed Tech (Berl) 47:315-7. 2002
    ..01) were significant. The PAT signal cannot substitute blood pressure but allows a good recognition of apneas and subcortical arousal and gives additional information on changes of sympathetic and parasympathetic tone during sleep...
  6. ncbi request reprint Prototypes and applications in neurotelemedicine
    T Penzel
    Sleep Laboratory, Department of Internal Medicine, Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Stud Health Technol Inform 78:89-100. 2000
    ..This overview presents the conceptual links between expert systems, the multimedia database, CD-ROM based tutorials and software tools in order to support neurological diagnostic and therapeutic practice in sleep, headache and epilepsy...
  7. ncbi request reprint Sleep atlas and multimedia database
    T Penzel
    Sleep Laboratory, Department of Internal Medicine, Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Stud Health Technol Inform 78:101-25. 2000
    ..A Java based viewer for biosignals provided in EDF format was installed in order to move free within the sleep recordings without the need to download the full recording on the client...
  8. ncbi request reprint Comparison of detrended fluctuation analysis and spectral analysis for heart rate variability in sleep and sleep apnea
    Thomas Penzel
    Division of Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstrasse 1, D 35033 Marburg, Germany
    IEEE Trans Biomed Eng 50:1143-51. 2003
    ..6% of the sleep stage assignments were correct, while using scaling analysis these numbers increased to 74.4% and 85.0%, respectively. We conclude that changes in HRV are better quantified by scaling analysis than by spectral analysis...
  9. ncbi request reprint A new design of a polysomnography-based multi-center treatment study for the restless legs syndrome
    T Penzel
    Schlafmedizinisches Labor, Klinik für Innere Medizin Pneumologie, Klinikum der Philipps Universität Marburg, Baldingerstrasse 1, D 35033, Marburg, Germany
    Clin Neurophysiol 113:571-8. 2002
    ..1 (range: -1.5 to 2.1). Using one scorer with a demonstrated high reliability in PSG scoring for all sleep recordings was very effective in terms of study cost, study duration, and data quality...
  10. ncbi request reprint Peripheral arterial tonometry, oximetry and actigraphy for ambulatory recording of sleep apnea
    Thomas Penzel
    Division for Pulmonary Diseases, Department of Internal Medicine, Hospital of Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Physiol Meas 25:1025-36. 2004
    ..Arousals are not unique to apnea events and therefore the specifity of the Watch-PAT is limited. In conclusion, the Watch-PAT is well suited to perform therapy control studies in patients suffering from sleep apnea and being treated...
  11. ncbi request reprint [Respiratory function diagnosis during sleep: possibilities and limitations]
    T Penzel
    Medizinische Poliklinik, Philipps Universitat, Marburg
    Pneumologie 51:444-9. 1997
    ..These evaluations still need further improvements. Nevertheless they can help to clarify the different types of respiratory regulation present in NREM-, REM-sleep and awake state...
  12. ncbi request reprint Sleep-related breathing disorder is an independent risk factor for systemic hypertension
    L Grote
    Schlafmedizinisches Labor, Medizinische Poliklinik, Universitat Marburg, Marburg, Germany
    Am J Respir Crit Care Med 160:1875-82. 1999
    ..SRBD is an independent risk factor for systemic hypertension with an increased likelihood in subjects </= 50 yr of age...
  13. ncbi request reprint [Sleep apnea, autonomic dysfunction and cardiovascular morbidity]
    U Koehler
    Klinik fur Innere Medizin, SP Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat, Baldingerstrasse 1, 35033 Marburg
    Internist (Berl) 43:1091-2, 1095-8. 2002
  14. ncbi request reprint [Why is obstructive sleep apnea (OSA) a cardiovascular risk factor?]
    U Koehler
    Klinik für Innere Medizin SP Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat Marburg, Baldingerstrasse 1, 35033 Marburg, Germany
    Z Kardiol 92:977-84. 2003
    ..The extent and need for therapy should be assessed by three criteria: 1) daytime symptoms, 2) the extent of breathing disorder and 3) cardiovascular comorbidity...
  15. doi request reprint ECG signal analysis for the assessment of sleep-disordered breathing and sleep pattern
    K Kesper
    Department for Internal Medicine, Section Respiratory Diseases, Faculty of Medicine, Philipps University Marburg, Baldingerstr 1, 35043 Marburg, Germany
    Med Biol Eng Comput 50:135-44. 2012
    ..7% of all 30 s epochs were correctly assigned by the algorithm. Although promising, these results underline the need for further testing in larger patient groups with different underlying diseases...
  16. ncbi request reprint Sympathetic activity is reduced by nCPAP in hypertensive obstructive sleep apnoea patients
    J Heitmann
    Sleep Laboratory, Division of Pulmonary Diseases, Dept of Internal Medicine, Marburg University, Germany
    Eur Respir J 23:255-62. 2004
    ..This may explain, at least in part, some of the discrepant results in previous treatment studies...
  17. ncbi request reprint [Machine-assisted detection of individually effective minimal CPAP pressure using the Vitalog HMS 5000 monitor]
    J Juhasz
    Medizinische Poliklinik, Philipps Universitat, Marburg
    Pneumologie 49:199-204. 1995
    ....
  18. ncbi request reprint Respiratory arousals in mild obstructive sleep apnea syndrome
    I Fietze
    Humboldt University, Medical School Charite, Department of Internal Medicine, Berlin, Germany
    Sleep 22:583-9. 1999
    ..Arousal analysis and detection of mild respiratory events associated with arousals are helpful in investigating the sleep structure and in objectifying clinical symptoms and treatment success in patients with mild OSAS...
  19. ncbi request reprint Expiratory flow limitation and intrinsic positive end-expiratory pressure in obesity
    W Pankow
    Department of Internal Medicine, Medizinische Poliklinik, Schlafmedizinisches Labor, Philipps University Marburg, D 32033 Marburg, Germany
    J Appl Physiol 85:1236-43. 1998
    ..We conclude that in OS 1) tidal breathing can be affected by EFL and PEEPi; 2) EFL and PEEPi are promoted by the supine posture; and 3) the increased diaphragmatic load in the supine position is, in part, related to PEEPi...
  20. ncbi request reprint Vigilance transitions in reaction time test: a method of describing the state of alertness more objectively
    R Conradt
    Schlafmedizinisches Labor, Philipps Universitat, Marburg, Germany
    Clin Neurophysiol 110:1499-509. 1999
    ..This method could be a very useful procedure, when an expert opinion is necessary. It also has an actual context to the discussion of the effectiveness of CPAP in the treatment of OSAS...
  21. ncbi request reprint [Nocturnal long-term recording of breath sounds in patients with bronchial asthma -- a reasonable diagnostic option?]
    U Koehler
    Klinik fur Innere Medizin, SP Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat, Marburg
    Pneumologie 59:872-8. 2005
    ..A mobile recording system provides a non-invasive monitoring at home which is independent of vigilance. Furthermore it can be used for follow-up examinations of medical interventions...
  22. ncbi request reprint Ambulatory diagnosis of sleep-related breathing disorders
    T Penzel
    , Marburg, Germany
    Sleep 15:S9-12. 1992
    ....
  23. ncbi request reprint Does short-term treatment with modafinil affect blood pressure in patients with obstructive sleep apnea?
    J Heitmann
    Department of Medicine, Marburg University, Germany
    Clin Pharmacol Ther 65:328-35. 1999
    ..To investigate the effects of modafinil, a central nonamphetamine awakening substance, on blood pressure and heart rate in hypersomnolent patients with obstructive sleep apnea...
  24. ncbi request reprint [Patient-ventilator interaction during noninvasive pressure supported spontaneous respiration in patients with hypercapnic COPD]
    W Pankow
    Zentrum fur Innere Medizin, Abteilung Medizinische Poliklinik, Zeitreihenlabor, Philipps Universitat, Marburg
    Pneumologie 55:7-12. 2001
    ..This study investigates the effects of NPSV via face mask on breathing pattern, ventilation and respiratory muscle loading in patients with hypercapnic stable COPD...
  25. ncbi request reprint [Status of cardiorespiratory polysomnographic diagnosis in the sleep laboratory]
    T Penzel
    Med. Poliklinik, , Schlafmedizinisches Labor, Marburg
    Pneumologie 49:98-102. 1995
    ..This first step of quality control is introduced to establish a procedure to keep quality of diagnosis and treatment on a high level in this medical specialty...
  26. ncbi request reprint [The history of percussion and auscultation]
    U Koehler
    Klinik fur Innere Medizin, SP Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat Marburg
    Pneumologie 58:525-30. 2004
  27. ncbi request reprint [Sleep disorders and sleep-related breathing disorders]
    H F Becker
    Schlafmedizinisches Labor, Klinik fur Innere Medizin, Philipps Universitat Marburg
    Internist (Berl) 45:57-81; quiz 82-3. 2004
    ....
  28. ncbi request reprint Long-term effects of pergolide in the treatment of restless legs syndrome
    K Stiasny
    Department of Neurology, Center of Nervous Diseases, Philipps University of Marburg, Germany
    Neurology 56:1399-402. 2001
    ..0001). Side effects, in particular nausea, were common but were well controlled by domperidone in most patients...
  29. ncbi request reprint [Effect of subcutaneous fatty tissue on normal respiratory sounds]
    V Gross
    Klinik fur Innere Medizin, SP Pneumologie, Philipps Universitat Marburg
    Biomed Tech (Berl) 48:182-5. 2003
    ..The results of this study show that the influence of subcutaneous fat layer is negligible and can be ignored in the automatic detection of lung sounds...
  30. ncbi request reprint [Obstructive sleep apnea, autonomic dysfunction and cardiovascular risk]
    U Koehler
    Klinik fur Innere Medizin, Schwerpunkt Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat Marburg
    Dtsch Med Wochenschr 128:1124-8. 2003
  31. ncbi request reprint [Acoustic follow-up of nocturnal bronchial obstruction therapy]
    U Koehler
    Klinik fur Innere Medizin, SP Pneumologie, Intensiv und Schlafmedizin, Philipps Universitat Marburg
    Pneumologie 57:198-201. 2003
    ..Acoustic long term monitoring confirms the reduction of nocturnal bronchial obstructions under therapy with beta 2-agonists. A better sleep quality may be expected from the improvement of the respiratory situation during sleep...
  32. ncbi request reprint [Dependence of nocturnal bronchial obstruction on sleep position]
    V Gross
    Philipps Universitat Marburg, 35033 Marburg, Deutschland
    Biomed Tech (Berl) 47:863-5. 2002
    ..From our results we can conclude that there is a small dependence of bronchial obstructions from sleep position. Further investigations are needed to verify this result...
  33. ncbi request reprint The relationship between normal lung sounds, age, and gender
    V Gross
    Department of Medicine, Philipps University, Marburg, Germany
    Am J Respir Crit Care Med 162:905-9. 2000
    ....
  34. ncbi request reprint [Acoustic analysis of nocturnal bronchial obstruction]
    U Koehler
    Klinik fur Innere Medizin, SP Pneumologie und Schlafmedizin, Philipps Universitat, Marburg, Germany
    Pneumologie 56:19-24. 2002
    ..Knowing about nocturnal bronchial obstructions helps to adapt the antiobstructive therapy. One can expect that an improvement of the respiratory situation also improves sleep quality...
  35. ncbi request reprint Automatic pressure titration with APAP is as effective as manual titration with CPAP in patients with obstructive sleep apnea
    Ingo Fietze
    Center of Sleep Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    Respiration 74:279-86. 2007
    ..Current options are autotitrating positive airway pressure (APAP) or manual titration with continuous positive airway pressure (CPAP). Procedures differ by parameters and by algorithms used for adapting pressure...
  36. ncbi request reprint Cardiovascular and respiratory dynamics during normal and pathological sleep
    Thomas Penzel
    Charité Center for Cardiology, Sleep Center, Charite University Hospital, Berlin, Germany
    Chaos 17:015116. 2007
    ..New derived variables can help to find indicators for these health risks...
  37. ncbi request reprint Heart rate and systolic blood pressure variability before and during obstructive sleep apnea episodes
    Martin Glos
    Center of Sleep Medicine, Charite Universitaetsmedizin 10117 Berlin, Germany
    Conf Proc IEEE Eng Med Biol Soc 2007:263-6. 2007
    ..The time-variant analysis of HRV and SBPV in the frequency range appears to be a suitable method for description of the relationship between the development of apnea and alterations in autonomous tone in patients with OSAS...
  38. ncbi request reprint Digital analysis and technical specifications
    Thomas Penzel
    Center for Sleep Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Clin Sleep Med 3:109-20. 2007
    ....
  39. ncbi request reprint The visual scoring of sleep in adults
    Michael H Silber
    Mayo Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
    J Clin Sleep Med 3:121-31. 2007
    ..Movement time was eliminated and major body movements defined. Studies are needed to test the reliability of the new rules. Future advances in technology may require modification of these rules with time...
  40. ncbi request reprint Mobile nocturnal long-term monitoring of wheezing and cough
    Volker Gross
    Klinik fur Innere Medizin, Schwerpunkt Pneumologie, Philipps Universitat Marburg, Marburg, Germany
    Biomed Tech (Berl) 52:73-6. 2007
    ..Our mobile system allows non-invasive and cooperation-independent nocturnal monitoring of acoustic symptoms in the domestic environment, especially at night, when most ailments occur...
  41. ncbi request reprint ENN-ICS--implementation and evaluation of a multilingual learning management system for sleep medicine in Europe
    Brigitte Knobl
    Sleep Laboratory, Hospital of Philipps University, Baldingerstr 1, D 35033 Marburg, Germany
    Stud Health Technol Inform 124:905-10. 2006
    ..The system architecture and its exemplary applications can be used as a model for future e-health services dealing with neurological and other medical topics...
  42. ncbi request reprint Nonrandom variability of respiration during sleep in healthy humans
    Sven Rostig
    SP Pneumologie, Philipps Universitat Marburg, Schlafmedizinisches Labor, Marburg, Germany
    Sleep 28:411-7. 2005
    ....
  43. ncbi request reprint An E-health solution for automatic sleep classification according to Rechtschaffen and Kales: validation study of the Somnolyzer 24 x 7 utilizing the Siesta database
    Peter Anderer
    Department of Psychiatry, Medical University of Vienna, Vienna, Austria
    Neuropsychobiology 51:115-33. 2005
    ..5% of the recordings) are changed, can definitely be neglected. Thus, the validation study proved the high reliability and validity of the Somnolyzer 24 x 7 and demonstrated its applicability in clinical routine and sleep studies...
  44. ncbi request reprint Perception of sleep: subjective versus objective sleep parameters in patients with Parkinson's disease in comparison with healthy elderly controls. Sleep perception in Parkinson's disease and controls
    Svenja Happe
    Dept of Clinical Neurology, University of Vienna, Vienna, Austria
    J Neurol 252:936-43. 2005
    ..Little is known about subjective sleep perception in patients with chronic somatic diseases...
  45. ncbi request reprint Sleep medicine as a scenario for medical grid application
    Sebastian Canisius
    Philipps University Marburg, Faculty of Medicine, Sleep Disorders Centre
    Stud Health Technol Inform 126:37-46. 2007
    ..Therefore, Grid based automatic analysis systems may improve the effectiveness of polysomnographic investigations and thereby diminish the costs for health care providers...
  46. ncbi request reprint Automated detection of obstructive sleep apnoea at different time scales using the electrocardiogram
    Philip de Chazal
    BiancaMed Ltd, NovaUCD, UCD, Belfield, Dublin 4, Ireland
    Physiol Meas 25:967-83. 2004
    ..The classifications from these epochs were combined to form an overall summary measure of minutes-of-SDR, allowing per-subject classification...
  47. ncbi request reprint Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea
    Heinrich F Becker
    Department of Respiratory Medicine, Philipps University Marburg, Marburg, Germany
    Circulation 107:68-73. 2003
    ..Therefore, we studied the effect of nCPAP on arterial hypertension in patients with OSA...
  48. ncbi request reprint Detection of sleep apnea from surface ECG based on features extracted by an autoregressive model
    Martin O Mendez
    Dept of Biomedical Engineering, Politecnico di Milano, Pzza Leonardo da Vinci 32, Italy
    Conf Proc IEEE Eng Med Biol Soc 2007:6106-9. 2007
    ..In addition it was possible to separate completely between Apnea and Normal subjects and almost completely among Apnea, Normal and Borderline subjects...
  49. doi request reprint Quantification of tonic and phasic muscle activity in REM sleep behavior disorder
    Geert Mayer
    Department of Neurology, Hephata Klinik, Schwalmstadt Treysa, Germany
    J Clin Neurophysiol 25:48-55. 2008
    ....
  50. pmc Common scale-invariant patterns of sleep-wake transitions across mammalian species
    Chung Chuan Lo
    Center for Polymer Studies and Department of Physics, Boston University, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 101:17545-8. 2004
    ..Our findings suggest common dynamical features of brief awakenings and sleep durations across species and may provide insights into the dynamics of the neural circuits controlling sleep...
  51. ncbi request reprint Characterization of sleep stages by correlations in the magnitude and sign of heartbeat increments
    Jan W Kantelhardt
    Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 65:051908. 2002
    ..Thus, the sign and the magnitude series provide information which is useful in distinguishing between the sleep stages...