Sajid Malik

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi Fifth finger camptodactyly maps to chromosome 3q11.2-q13.12 in a large German kindred
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Eur J Hum Genet 16:265-9. 2008
  2. ncbi A novel type of autosomal recessive syndactyly: clinical and molecular studies in a family of Pakistani origin
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Marburg, Germany
    Am J Med Genet A 126:61-7. 2004
  3. doi Congenital, low penetrance lymphedema of lower limbs maps to chromosome 6q16.2-q22.1 in an inbred Pakistani family
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, 35037, Marburg, Germany
    Hum Genet 123:197-205. 2008
  4. doi Synpolydactyly: clinical and molecular advances
    S Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Clin Genet 73:113-20. 2008
  5. ncbi Autosomal recessive mesoaxial synostotic syndactyly with phalangeal reduction maps to chromosome 17p13.3
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Am J Med Genet A 134:404-8. 2005
  6. pmc Synpolydactyly and HOXD13 polyalanine repeat: addition of 2 alanine residues is without clinical consequences
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr, 7, 35037 Marburg, Germany
    BMC Med Genet 8:78. 2007
  7. ncbi A simple method for characterising syndactyly in clinical practice
    S Malik
    Zentrum für Humangenetik, Klinikum der Philipps Universität Marburg, Germany
    Genet Couns 16:229-38. 2005
  8. ncbi Evidence for clinical and genetic heterogeneity of syndactyly type I: the phenotype of second and third toe syndactyly maps to chromosome 3p21.31
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, 35037 Marburg, Germany
    Eur J Hum Genet 13:1268-74. 2005
  9. pmc Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development
    Amir A Abbasi
    Department of Human Genetics, Philipps Universitat Marburg, 35037 Marburg, Germany
    BMC Dev Biol 10:44. 2010
  10. pmc Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers
    Amir Ali Abbasi
    Institute of Human Genetics, Philipps University, Marburg, Germany
    PLoS ONE 2:e366. 2007

Collaborators

Detail Information

Publications14

  1. ncbi Fifth finger camptodactyly maps to chromosome 3q11.2-q13.12 in a large German kindred
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Eur J Hum Genet 16:265-9. 2008
    ..Since genetic heterogeneity for isolated camptodactyly is likely, we propose to designate the 3q11.2-q13.12 locus as CAMPD1 (ie, camptodactyly 1)...
  2. ncbi A novel type of autosomal recessive syndactyly: clinical and molecular studies in a family of Pakistani origin
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Marburg, Germany
    Am J Med Genet A 126:61-7. 2004
    ..We show that the phenotype in our family is not linked to chromosomal regions 2q34-q36, 2q31, and 6q22-q23 encompassing loci for syndactyly types I, II, and III...
  3. doi Congenital, low penetrance lymphedema of lower limbs maps to chromosome 6q16.2-q22.1 in an inbred Pakistani family
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, 35037, Marburg, Germany
    Hum Genet 123:197-205. 2008
    ..Our study provides an evidence of a second locus for lymphedema type I. The discovery of the underlying gene could be helpful for the understanding of this heterogeneous hereditary condition...
  4. doi Synpolydactyly: clinical and molecular advances
    S Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Clin Genet 73:113-20. 2008
    ..Our lumping and splitting scheme for SPD phenotypic variants could be useful for the understanding of this interesting malformation...
  5. ncbi Autosomal recessive mesoaxial synostotic syndactyly with phalangeal reduction maps to chromosome 17p13.3
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, Marburg, Germany
    Am J Med Genet A 134:404-8. 2005
    ....
  6. pmc Synpolydactyly and HOXD13 polyalanine repeat: addition of 2 alanine residues is without clinical consequences
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr, 7, 35037 Marburg, Germany
    BMC Med Genet 8:78. 2007
    ..It has been suggested that expansions < or = 6 alanine residues go without medical attention, as no such expansion has ever been reported with the SPD1 phenotype...
  7. ncbi A simple method for characterising syndactyly in clinical practice
    S Malik
    Zentrum für Humangenetik, Klinikum der Philipps Universität Marburg, Germany
    Genet Couns 16:229-38. 2005
    ..It might encourage clinicians to report families that are still unclassifed and thus, helping to extend and improve the existing classification system...
  8. ncbi Evidence for clinical and genetic heterogeneity of syndactyly type I: the phenotype of second and third toe syndactyly maps to chromosome 3p21.31
    Sajid Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Bahnhofstr 7, 35037 Marburg, Germany
    Eur J Hum Genet 13:1268-74. 2005
    ..20 Mb. Since the same phenotype appears not to be linked to this locus in a German family, we predict genetic heterogeneity in zygodactyly and propose to designate the 3p21.31 locus as ZD1 (i.e., zygodactyly 1)...
  9. pmc Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development
    Amir A Abbasi
    Department of Human Genetics, Philipps Universitat Marburg, 35037 Marburg, Germany
    BMC Dev Biol 10:44. 2010
    ..From these studies it has emerged, that Gli3 expression must be subject to a tight spatiotemporal regulation. However, the genetic mechanisms and the cis-acting elements controlling the expression of Gli3 remained largely unknown...
  10. pmc Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers
    Amir Ali Abbasi
    Institute of Human Genetics, Philipps University, Marburg, Germany
    PLoS ONE 2:e366. 2007
    ....
  11. ncbi Genetic heterogeneity of synpolydactyly: a novel locus SPD3 maps to chromosome 14q11.2-q12
    S Malik
    Zentrum für Humangenetik, Philipps Universitat Marburg, Germany
    Clin Genet 69:518-24. 2006
    ..72 Mb. We propose to allocate to this locus the symbol SPD3 (synpolydactyly 3), and to name the loci associated with HOXD13 or FBLN1 mutations SPD1 and SPD2, respectively...
  12. ncbi A novel locus of ectodermal dysplasia maps to chromosome 10q24.32-q25.1
    Muhammad Arshad Rafiq
    Department of Biological Sciences, Quaid i Azam University, Islamabad, Pakistan
    J Invest Dermatol 124:338-42. 2005
    ..92 cM interval flanked by markers D10S1710 and D10S1741 on chromosome 10q24.32-q25.1. Multipoint linkage analysis generated a maximum logarithm of odds ratio score of 4.79 in the interval D10S1239-D10S1264, which corresponds to 6.35 Mb...
  13. ncbi A locus for hereditary hypotrichosis localized to human chromosome 18q21.1
    Muhammad Arshad Rafique
    Department of Biological Sciences, Quaid i Azam University, Islamabad, Pakistan
    Eur J Hum Genet 11:623-8. 2003
    ..The expression in epidermal desmosomes and their connection to the keratin intermediate filaments make these genes excellent candidates for recessive hypotrichosis...
  14. ncbi Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene
    Aicha Salhi
    Department of Dermatology, University of Algiers, Algiers, Algeria
    Cancer Res 64:5113-7. 2004
    ..Hence, mutations of the tumor suppressor gene CYLD at 16q12-q13 may give rise to familial TE indistinguishable from the phenotype assigned to 9p21...