B Maisch

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Definition of inflammatory cardiomyopathy (myocarditis): on the way to consensus. A status report
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:200-9. 2000
  2. ncbi request reprint Human viral cardiomyopathy
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Front Biosci 8:s39-67. 2003
  3. ncbi request reprint [Dilated cardiomyopathy and myocarditis. Current diagnostic requirements and therapeutic possibilities]
    B Maisch
    Klinik für Innere Medizin Kardiologie, Angiologie, Intensivmedizin und Präventive Kardiologie der Philipps Universität Marburg, Baldinger Strasse 1, Postfach 23 60, 35033 Marburg
    Internist (Berl) 43:S45-6, S49-65. 2002
  4. ncbi request reprint Dilated cardiomyopathies as a cause of congestive heart failure
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Angiology, Intensive Care Medicine, and Preventive Cardiology, Philipps University, Marburg, Germany
    Herz 27:113-34. 2002
  5. ncbi request reprint Prevalence of viral genome in endomyocardial biopsies from patients with inflammatory heart muscle disease
    S Pankuweit
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:221-6. 2000
  6. ncbi request reprint Cytokine activation in pericardial fluids in different forms of pericarditis
    S Pankuweit
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:748-54. 2000
  7. ncbi request reprint B-type natriuretic peptide and wall stress in dilated human heart
    P Alter
    Internal Medicine, Cardiology, Philipps University, Baldingerstrasse, Marburg, Germany
    Mol Cell Biochem 314:179-91. 2008
  8. ncbi request reprint New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:769-80. 2000
  9. ncbi request reprint Apoptosis in myocarditis and dilated cardiomyopathy: does enterovirus genome persistence protect from apoptosis? An endomyocardial biopsy study
    P Alter
    Department of Internal Medicine and Cardiology, Philipps University Marburg Lahn, Baldingerstrasse, D 35033, Marburg, Germany
    Cardiovasc Pathol 10:229-34. 2001
  10. ncbi request reprint Intrapericardial treatment of autoreactive myocarditis with triamcinolon. Successful administration in patients with minimal pericardial effusion
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Germany
    Herz 25:781-6. 2000

Collaborators

Detail Information

Publications144 found, 100 shown here

  1. ncbi request reprint Definition of inflammatory cardiomyopathy (myocarditis): on the way to consensus. A status report
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:200-9. 2000
    ..Additionally, a brief overview is presented stating the current knowledge on effector mechanisms of the immune system in myocarditis and dilated cardiomyopathy...
  2. ncbi request reprint Human viral cardiomyopathy
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Front Biosci 8:s39-67. 2003
    ..The most frequent cardiotropic viruses detected by endomyocardial biopsy are Parvo B19, enteroviruses, adenoviruses, cytomegalovirus, and less frequently Epstein-Barr virus, and influenza virus...
  3. ncbi request reprint [Dilated cardiomyopathy and myocarditis. Current diagnostic requirements and therapeutic possibilities]
    B Maisch
    Klinik für Innere Medizin Kardiologie, Angiologie, Intensivmedizin und Präventive Kardiologie der Philipps Universität Marburg, Baldinger Strasse 1, Postfach 23 60, 35033 Marburg
    Internist (Berl) 43:S45-6, S49-65. 2002
  4. ncbi request reprint Dilated cardiomyopathies as a cause of congestive heart failure
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Angiology, Intensive Care Medicine, and Preventive Cardiology, Philipps University, Marburg, Germany
    Herz 27:113-34. 2002
    ..If no inflammation is observed in the biopsy of a dilated heart (< 14 lymphocytes and macrophages/mm2), the term viral cardiomyopathy or viral persistence in dilated cardiomyopathy should be applied...
  5. ncbi request reprint Prevalence of viral genome in endomyocardial biopsies from patients with inflammatory heart muscle disease
    S Pankuweit
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:221-6. 2000
    ..These findings have to be taken into account in future diagnostic and therapeutic studies in the field of cardiomyopathies...
  6. ncbi request reprint Cytokine activation in pericardial fluids in different forms of pericarditis
    S Pankuweit
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:748-54. 2000
    ..In the future, this may have therapeutic implications...
  7. ncbi request reprint B-type natriuretic peptide and wall stress in dilated human heart
    P Alter
    Internal Medicine, Cardiology, Philipps University, Baldingerstrasse, Marburg, Germany
    Mol Cell Biochem 314:179-91. 2008
    ..It is concluded that the diagnostic use of BNP should primarily be directed to assess ventricular wall stress rather than the extent of functional ventricular impairment in LVD...
  8. ncbi request reprint New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Germany
    Herz 25:769-80. 2000
    ....
  9. ncbi request reprint Apoptosis in myocarditis and dilated cardiomyopathy: does enterovirus genome persistence protect from apoptosis? An endomyocardial biopsy study
    P Alter
    Department of Internal Medicine and Cardiology, Philipps University Marburg Lahn, Baldingerstrasse, D 35033, Marburg, Germany
    Cardiovasc Pathol 10:229-34. 2001
    ..The purpose of this study was to examine the role of apoptosis in myocarditis and dilated cardiomyopathy. Apoptosis is an active energy-consuming mechanism of cell death in several cardiac diseases in different quality and quantity...
  10. ncbi request reprint Intrapericardial treatment of autoreactive myocarditis with triamcinolon. Successful administration in patients with minimal pericardial effusion
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Germany
    Herz 25:781-6. 2000
    ..Pericardiocentesis was enabled by means of the PerDUCER device, facilitated by pericardioscopy...
  11. ncbi request reprint Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors
    P Alter
    University of Marburg Lahn, Department of Internal Medicine Cardiology, Baldingerstrasse, 35033 Marburg, Germany
    Z Kardiol 93:524-32. 2004
    ..Apoptosis causes loss of contractile cardiomyocytes in inflammatory heart disease. Despite recent examinations, the influence of virus infection on apoptosis remained ill-defined...
  12. ncbi request reprint Mitochondrial DNA deletions in cardiomyopathies
    V Ruppert
    Department of Internal Medicine and Cardiology, Philipps University Marburg, Germany
    Herz 25:161-7. 2000
    ..A general pathogenic effect on the development of dilated cardiomyopathy is less likely. The mutations may be a sign of increasing stress to the heart, however, thus promoting consecutive damage of mtDNA by initiating a vicious circle...
  13. ncbi request reprint Guidelines on the diagnosis and management of pericardial diseases executive summary; The Task force on the diagnosis and management of pericardial diseases of the European society of cardiology
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Germany
    Eur Heart J 25:587-610. 2004
  14. ncbi request reprint Alcohol and the heart
    M Schoppet
    Department of Internal Medicine, Cardiology and Angiology, Philipps University Marburg, Germany
    Herz 26:345-52. 2001
    ..Alcohol interferes with other medications, and drinking can exacerbate a variety of medical illnesses...
  15. doi request reprint Intrapericardial procedures for cardiac regeneration by stem cells: need for minimal invasive access (AttachLifter) to the normal pericardial cavity
    H Rupp
    Department of Internal Medicine Cardiology, Experimental Cardiology Laboratory, Philipps University of Marburg, Marburg, Deutschland
    Herz 35:458-65. 2010
    ..A fiberscope can be used to inspect the pericardium prior to puncture. Based on these procedures, the role of the pericardial space and the presence of pericardial effusion in cardiac regeneration can be assessed...
  16. ncbi request reprint Relation of B-type natriuretic peptide to left ventricular wall stress as assessed by cardiac magnetic resonance imaging in patients with dilated cardiomyopathy
    P Alter
    Philipps University, Internal Medicine Cardiology, Baldingerstrasse, D 35033 Marburg, Germany
    Can J Physiol Pharmacol 85:790-9. 2007
    ..g., EF) appear to be secondary. Since an increased wall stress is associated with cardiac dilatation, early diagnosis and treatment could potentially prevent worsening of the outcome...
  17. ncbi request reprint Osteoprotegerin gene polymorphisms in men with coronary artery disease
    Muhidien Soufi
    Department of Internal Medicine and Cardiology, Philipps University, Marburg, Germany
    J Clin Endocrinol Metab 89:3764-8. 2004
    ..02). In summary, linkage of genetic variations of the OPG gene at positions 950 and 1181 may confer an increased risk of CAD in Caucasian men...
  18. ncbi request reprint Current treatment options in (peri)myocarditis and inflammatory cardiomyopathy
    B Maisch
    Department of Internal Medicine and Cardiology, University Hospital Gießen and Marburg, 35043, Marburg, Germany
    Herz 37:644-56. 2012
    ..In virus-negative, autoreactive perimyocardial disease a locoregional approach with intrapericardial instillation of high local doses of triamcinolone acetate has been shown to be highly efficient and with few systemic side-effects...
  19. ncbi request reprint Cardiotoxicity of 5-fluorouracil
    P Alter
    Philipps University of Marburg Lahn, Department of Internal Medicine Cardiology, Baldingerstrasse, 35033 Marburg, Germany
    Cardiovasc Hematol Agents Med Chem 4:1-5. 2006
    ..It could be assumed that 5-FU toxicity is reversible in the majority of cases when acute complications, e.g., arrhythmias, are resolved...
  20. ncbi request reprint A new methodological approach to assess cardiac work by pressure-volume and stress-length relations in patients with aortic valve stenosis and dilated cardiomyopathy
    P Alter
    Internal Medicine Cardiology, Philipps University, Baldingerstrasse, 35033 Marburg, Germany
    Pflugers Arch 455:627-36. 2008
    ..Most likely, deterioration of myocardial work is crucial for the prognosis. It is suggested to include these basic physiological procedures in the clinical assessment of the pump function of the heart...
  21. doi request reprint [Classification, genetic predisposition and risk factors for the development of cardiomyopathies]
    S Pankuweit
    Klinik für Innere Medizin Kardiologie, Universitätsklinikum Giessen und Marburg, Standort Marburg, Baldingerstrasse, 35043, Marburg, Germany
    Internist (Berl) 49:441-2, 444-7. 2008
    ..Nevertheless, much more progress in the identification of underlying mutations, susceptibility genes and modifier genes is important and indispensable for the development of new etiology orientated forms of therapy...
  22. pmc Heart rate variability and baroreflex sensitivity in idiopathic dilated cardiomyopathy
    J Hoffmann
    Department of Internal Medicine and Cardiology, Hospital of the Philipps University of Marburg, Baldingerstrasse, 35033 Marburg, Germany
    Heart 83:531-8. 2000
    ....
  23. ncbi request reprint Prevalence of the parvovirus B19 genome in endomyocardial biopsy specimens
    Sabine Pankuweit
    Department of Internal Medicine Cardiology and Patholody, Philipps University Marburg, Marburg, Germany
    Hum Pathol 34:497-503. 2003
    ..PVB19 should therefore be recognized as a potential cardiotropic pathogen in patients of all ages...
  24. ncbi request reprint Acute parvovirus B19 infection associated with myocarditis in an immunocompetent adult
    Steffen Lamparter
    Department of Internal Medicine and Cardiology, Philipps University, Marburg, Germany
    Hum Pathol 34:725-8. 2003
    ..Because PVB19 myocarditis may progress to chronic dilated cardiomyopathy, early diagnosis by endomyocardial biopsy is important to initiate anti-inflammatory treatment...
  25. ncbi request reprint Pathophysiology of viral myocarditis: the role of humoral immune response
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Baldingerstrasse 1, D 35033 Marburg, Germany
    Cardiovasc Pathol 11:112-22. 2002
    ..This paper reviews our present knowledge on the humoral immune response in myocarditis and its interplay with the viral agents and the other components of the immune system...
  26. ncbi request reprint [Arterial hypertension and metabolic syndrome]
    Michael Christ
    Klinik fur Innere Medizin, Kardiologie, Angiologie, Intensivmedizin und Prävention, Philipps Universitat, Marburg, Germany
    Herz 28:674-85. 2003
    ..Due to its adverse impact on cardiovascular disease, early detection and aggressive treatment is mandatory to ensure longlasting benefits for affected patients...
  27. ncbi request reprint Management of patients with suspected (peri-)myocarditis and inflammatory dilated cardiomyopathy
    Bernhard Maisch
    Department of Internal Medicine Cardiology, UKGM GmbH and Philipps University Marburg, Baldingerstrasse, 35043, Marburg, Germany
    Herz 31:881-90. 2006
    ..A case of active parvo B19-positive myocarditis demonstrates the role of immunoglobulin treatment under these conditions...
  28. ncbi request reprint Treatment of inflammatory dilated cardiomyopathy and (peri)myocarditis with immunosuppression and i.v. immunoglobulins
    Bernhard Maisch
    Department of Internal Medicine and Cardiology, Philipps University Marburg, Germany
    Herz 29:624-36. 2004
    ....
  29. ncbi request reprint Inflammatory cardiomyopathy
    Konstantinos Karatolios
    Department of Internal Medicine and Cardiology, University Hospital of Giessen and Marburg, Philipps University Marburg, Germany
    Hellenic J Cardiol 47:54-65. 2006
  30. ncbi request reprint Neoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatin
    B Maisch
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Germany
    Eur Heart J 23:1625-31. 2002
    ..To evaluate the clinical efficacy, safety, and long-term effect of intrapericardial treatment with cisplatin in large neoplastic pericardial effusions...
  31. pmc Autoantibodies in the sera of patients with rheumatic heart disease: characterization of myocardial antigens by two-dimensional immunoblotting and N-terminal sequence analysis
    D Tontsch
    Department of Internal Medicine Cardiology, Philipps University of Marburg, Marburg, Germany
    Clin Exp Immunol 121:270-4. 2000
    ..Mitochondrial proteins have been implicated in the pathogenesis of inflammatory heart disease for some years, and in this study we have identified two mitochondrial proteins as relevant antigens in rheumatic heart disease...
  32. ncbi request reprint Antiendothelial antibodies in sera of patients with infective endocarditis
    I Portig
    Klinikum der Philipps Universität SP Kardiologie, Marburg, Germany
    Basic Res Cardiol 96:75-81. 2001
    ..These antibodies may develop as a consequence of damage to endocardial cells (thereby exposing intracellular antigen to the immune system) and do not seem to play a role in the pathogenesis of infective endocarditis...
  33. ncbi request reprint Functional determination of plasmin in arginine-stabilized plasma
    T W Stief
    Department of Clinical Chemistry, Hospital of Philipps University Marburg, Germany
    Clin Appl Thromb Hemost 11:303-9. 2005
    ....
  34. ncbi request reprint Functional determination of plasminogen activator in arginine-stabilized plasma
    T W Stief
    Department of Clinical Chemistry, Hospital of Philipps University, Marburg, Germany
    Clin Appl Thromb Hemost 11:311-23. 2005
    ....
  35. ncbi request reprint In vitro simulation of therapeutic plasmatic fibrinolysis
    T W Stief
    Department of Clinical Chemistry, Hospital of Philipps University Marburg, Germany
    Clin Appl Thromb Hemost 9:211-20. 2003
    ..Clinical thrombolysis might be improved by usage of more physiologic activators of thrombolysis, such as activators of polymorphonuclear neutrophils...
  36. ncbi request reprint Invasive techniques--from diagnosis to treatment
    B Maisch
    Department of Internal Medicine and Cardiology, University Hospital of Giessen and Marburg, Baldingerstr, 35043 Marburg, Germany
    Rheumatology (Oxford) 45:iv32-8. 2006
    ..Before corticoid treatment is started, a viral or microbial aetiology has to be excluded at the site of cardiac inflammation. This again can only be done by the analysis of cardiac tissue samples...
  37. ncbi request reprint [Recurrent autoreactive pericardial effusion. Impact of an aetiological classification of pericarditis]
    B Maisch
    Klinik für Innere Medizin Schwerpunkt Kardiologie der Universitätsklinikums GmbH Gissen und Marburg, Standort Marburg
    Dtsch Med Wochenschr 131:2143-6. 2006
    ..The symptoms improved after one week of treatment with diclofenac and the ECG had become normal. Two months later the patient was seen at our cardiac outpatient clinic. He had night sweats, sporadic precordial pain and severe dyspnoe...
  38. ncbi request reprint Monitoring of plasmin and plasminogen activator activity in blood of patients under fibrinolytic treatment by reteplase
    T W Stief
    Department of Laboratory Medicine, Hospital of Philipps University Marburg, Germany
    Clin Appl Thromb Hemost 12:213-8. 2006
    ..e., polymorphonuclear phagocytes (PMN) that can be activated by singlet oxygen ((1)O(2)). PMN might be superior to PA in selective lysis of pathologic thrombi...
  39. doi request reprint [New possibilities of diagnostics and therapy of pericarditis]
    B Maisch
    Klinik fur Innere Medizin, Schwerpunkt Kardiologie, Universitätsklinikum Giessen und Marburg, Baldingerstrasse 1, 35033, Marburg, Deutschland
    Internist (Berl) 49:17-26. 2008
    ..In autoreactive pericarditis intrapericardial instillation of triamcinolone is effective with few side effects. In malignant pericarditis the intrapericardial administration of cisplatin prevents early recurrences...
  40. ncbi request reprint [Endomyocardial biopsy-guided diagnosis and treatment of inflammatory cardiomyopathies]
    S Pankuweit
    Klinik für Innere Medizin Kardiologie, Philipps Universitat Marburg
    Dtsch Med Wochenschr 129:2169-72. 2004
    ....
  41. ncbi request reprint [Metabolism and the hypertrophied heart of the elderly]
    H Rupp
    Molekular kardiologisches Labor, Klinik für Innere Medizin und Kardiologie, Philipps Universitat Marburg, Marburg
    Dtsch Med Wochenschr 130:726-30. 2005
    ....
  42. pmc Giant left atrial mass in an asymptomatic patient
    S Lamparter
    Department of Internal Medicine and Cardiology, Heart Centre, Philipps University of Marburg, Marburg, Germany
    Heart 90:e24. 2004
    ..Although the tumour occupied a large part of the left atrium the patient remained in sinus rhythm and displayed no symptoms...
  43. ncbi request reprint [The heart in cases of viral, bacterial and parasitic infections]
    B Maisch
    Klinik fur Innere Medizin, Schwerpunkt Kardiologie, Universitätsklinikum Giessen und Marburg, Baldingerstr 1, 35033 Marburg, Deutschland
    Internist (Berl) 48:255-67. 2007
    ..Infective agents and their adequate diagnosis and treatment are discussed for these clinical entities according to current guidelines and clinical pathways...
  44. doi request reprint [Biventricular stimulation for AV block]
    R C Funck
    Universitätsklinikum Giessen und Marburg, Standort Marburg Klinik für Innere Medizin Kardiologie, Angiologie und Kardioprävention, Marburg
    Herzschrittmacherther Elektrophysiol 19:41-7. 2008
    ..Both societies do expressly permit the implantation of biventricular systems with ICD backup if indicated...
  45. ncbi request reprint Restenosis after percutaneous coronary interventions and infection
    M Herzum
    Department of Internal Medicine, Philipps University of Marburg
    Herz 25:91-4. 2000
    ..Further studies in this field may identify patients at a high risk for atherogenesis and restenosis. Their results should be helpful in treating restenosis after percutaneous coronary interventions...
  46. ncbi request reprint [Fulminant course of falciparum malaria]
    S Lamparter
    Klinik für Innere Medizin SP Kardiologie, Philipps Universitat Marburg
    Dtsch Med Wochenschr 126:76-8. 2001
    ..Autopsy revealed prominent congestion of liver, spleen and cerebral vessels as well as subdural and subarachnoidal hemorrhage...
  47. ncbi request reprint Angiography, CT and MR imaging of a high vena cava inferior interruption in a patient with Hirschsprung disease
    P Alter
    Department of Internal Medicine, Cardiology, Philipps University Marburg Lahn, Germany
    Vasa 30:299-302. 2001
    ..We suggest that the association of these two malformations are most likely interrelated and should be considered as a new syndrome...
  48. ncbi request reprint [Prevention of atrial arrhythmias by pacing]
    R C Funck
    Klinik für Innere Medizin Kardiologie, Philipps Universitat Marburg
    Herz 26:18-29. 2001
    ..Atrial fibrillation is the most frequent arrhythmia. It can impair quality of life considerably. Due to thromboembolic complications it contributes to the patients' morbidity and mortality and to the costs for their medical treatment...
  49. ncbi request reprint [Significance of matrix metalloproteinases in cardiovascular diseases]
    S Lamparter
    Klinik für Innere Medizin Schwerpunkt Kardiologie, Marburg
    Z Kardiol 89:949-57. 2000
    ..The role of MMPs in these cardiovascular diseases and possible therapeutic options are the focus of this review...
  50. ncbi request reprint [Therapy of dilated cardiomyopathies with and without inflammation]
    G Hufnagel
    Abteilung Innere Medizin Schwerpunkt Kardiologie, Philipps Universitat Marburg
    Med Klin (Munich) 93:240-51. 1998
    ..Specific therapies are aimed to avoid the progression of the disease which may ultimately lead to heart failure with a cardiac assist device or heart transplantation as ultimate therapeutic option...
  51. ncbi request reprint The European Study of Epidemiology and Treatment of Cardiac Inflammatory Diseases (ESETCID). First epidemiological results
    G Hufnagel
    Department of Internal Medicine and Cardiology, Philipps University of Marburg, Germany
    Herz 25:279-85. 2000
    ....
  52. ncbi request reprint Arrhythmias in acute pericarditis. An endomyocardial biopsy study
    A D Ristic
    University Institute for Cardiovascular Diseases, Medical Centre of Serbia, Belgrade, Yugoslavia
    Herz 25:729-33. 2000
    ..On the contrary, incidence of transitory atrial fibrillation was higher in acute pericarditis, than in myocarditis...
  53. doi request reprint [Tumor markers in the assessment of malignant and benign pericardial effusion]
    K Karatolios
    Klinik fur Innere Medizin, Schwerpunkte Kardiologie, Angiologie, Internistische Intensivmedizin und Prävention, Universitätsklinikum Giessen und Marburg GmbH, Deutschland
    Herz 36:290-5. 2011
    ....
  54. doi request reprint Treatment of cardiovascular diseases in cancer patients
    M Noutsias
    Department of Internal Medicine Cardiology, University Hospital of Marburg and Giessen UKGM GmbH, Philipps Universitat Marburg, Deutschland
    Herz 36:340-5. 2011
    ..Further clinical research focused on the pathogenesis and treatment of cardiovascular diseases in cancer patients is warranted to pave the way to guidelines for this nonhomogeneous patient group...
  55. ncbi request reprint [Angina pectoris in extracoronary diseases]
    A Wilke
    Klinik für Innere Medizin Kardiologie, Philipps Universitat Marburg
    Herz 24:132-9. 1999
    ..Diffuse esophageal spasm is the extracardiac condition that is confused most often with ischemic cardiac chest pain. This pain presents as a deep thoracic pain that may be present over most of the thorax. It may extend down the anterome..
  56. ncbi request reprint [Endothelial dysfunction--assessment of current status and approaches to therapy]
    B C Simon
    Klinik für Innere Medizin Kardiologie, Philipps Universitat Marburg
    Herz 24:62-71. 1999
    ..Continuous endothelial dysfunction and activation, caused by risk factors and infection, represent the basis for atherogenesis and acute coronary syndromes...
  57. ncbi request reprint [Amiodarone induced pulmonary toxicity]
    P Alter
    Zentrum für Innere Medizin Kardiologie, Philipps Universität Marburg Lahn, Germany
    Pneumologie 56:31-5. 2002
    ..In contrast to patients with coronary artery disease, there are only a few data about pulmonary toxicity in patients with dilated cardiomyopathy...
  58. ncbi request reprint Schedule-induced psychological stress and molecular structures of cardiomyocytes
    H Rupp
    Institute of Physiology, University of Tubingen, Germany
    Am J Physiol 272:R776-82. 1997
    ....
  59. ncbi request reprint [Cardiotropic DNA viruses and bacteria in the pathogenesis of dilated cardiomyopathy with or without inflammation]
    S Pankuweit
    Abteilung Innere Medizin Schwerpunkt Kardiologie, Philipps Universitat Marburg
    Med Klin (Munich) 93:223-8. 1998
    ..Patients with a positive PCR for Borrelia burgdorferi should be treated with 3rd generation cephalosporines and/or sublactam...
  60. ncbi request reprint [Cell death in inflammatory heart muscle diseases--apoptosis or necrosis?]
    S Pankuweit
    Klinik für Innere Medizin und Kardiologie, Philipps Universitat Marburg
    Herz 24:211-8. 1999
    ..Therefore, studies on the extent of apoptotic processes in diseased versus healthy cardiac tissue are of great importance...
  61. ncbi request reprint Control of apoptosis of cardiovascular fibroblasts: a novel drug target
    H Rupp
    Department of Internal Medicine and Cardiology, Philipps University of Marburg, Germany
    Herz 24:225-31. 1999
    ..A candidate approach could involve growth factor analogues which are known to induce fibroblast apoptosis when an incomplete growth stimulus persists...
  62. ncbi request reprint [Prevention of coronary heart disease--"evidence-based medicine" of antilipemic therapy]
    J R Schaefer
    Zentrum Innere Medizin, Kardiologie, Philipps Universitat Marburg
    Herz 24:3-12. 1999
    ..The challenge for clinicians is to apply the important lessons learned from these clinical trials to an "evidence-based" patient care...
  63. ncbi request reprint Strategies to optimize CAD prevention in modern cardiology. The "Marburg CAD Prevention Project"
    J R Schaefer
    Department of Internal Medicine and Cardiology, University Hospital Marburg, Germany
    Herz 25:113-6. 2000
    ..This approach ensures that at least all of our patients with documented CAD receive the appropriate preventional recommendations and treatment...
  64. doi request reprint [Preoperative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. The 2009 ESC guidelines]
    A Richter
    Klinik für Innere Medizin und Kardiologie, Universitätsklinikum Gießen und Marburg, Standort Marburg, Baldingerstr, 35043, Marburg
    Herz 35:550-6. 2010
    ..These guidelines are straightforward and feasible for cardiologists as well as specialists in internal medicine and general practicioners. Nevertheless, some points still lack evidence...
  65. doi request reprint Differential diagnosis of pericardial effusion after stem cell transplantation in acute myeloic leukemia
    B Maisch
    Department of Internal Medicine and Cardiology, University Hospital Gießen and Marburg UKGM GmbH and Philipps University Marburg, Deutschland
    Herz 36:352-4. 2011
    ..An intrapericardial instillation of 1000 mg triamcinolone acetate at day 1 and 50 mg/m(2) cisplatin at day 3 effectively prevented the recurrence of tamponade, but could not prevent a lethal outcome 3 weeks later...
  66. ncbi request reprint Outcomes of elderly recipients of implantable cardioverter defibrillators
    Wolfram Grimm
    Department of Cardiology, Hospital of the Philipps University of Marburg, Philipps University of Marburg, Germany
    Pacing Clin Electrophysiol 30:S134-8. 2007
    ..To examine the patterns of use, complication rates, and survival in elderly recipients of implantable cardioverter defibrillators (ICD)...
  67. ncbi request reprint [Myocardial fibrosis: a cardiopathophysiologic Janus head]
    Bernhard Maisch
    Direktor der Klinik für Innere Medizin Kardiologie, Angiologie, Intensivmedizin und Kardioprävention, Philipps Universitat, Baldingerstrasse, 35043, Marburg, Germany
    Herz 31:260-8. 2006
  68. ncbi request reprint Inflammatory dilated cardiomyopathy (DCMI)
    Bernhard Maisch
    Department of Internal Medicine Cardiology, Philipps University Marburg, Baldingerstrasse, 35043, Marburg, Germany
    Herz 30:535-44. 2005
    ..By this approach a new insight in the familial clustering of other autoimmune diseases in patients with DCM and in genetic predisposition can be expected...
  69. ncbi request reprint Familial inflammatory dilated cardiomyopathy
    Irene Portig
    Philipps University Hospital, Department of Internal Medicine and Cardiology, Baldingerstrasse, 35033 Marburg, Germany
    Eur J Heart Fail 8:816-25. 2006
    ..Mutations in genes encoding proteins responsible for myocardial architecture have been identified, but additional pathophysiological mechanisms including inflammatory reactions have been proposed...
  70. ncbi request reprint Heart rate variability in patients with cardiac hypertrophy--relation to left ventricular mass and etiology
    Peter Alter
    Department of Internal Medicine Cardiology, Philipps University of Marburg, D 35033 Marburg, Germany
    Am Heart J 151:829-36. 2006
    ..To date, only few data are available on HRV in patients with predominant diastolic dysfunction in the presence of cardiac hypertrophy of different etiologies...
  71. ncbi request reprint Non-compaction cardiomyopathy in an adult with hereditary spherocytosis
    Peter Alter
    Philipps University of Marburg, Department of Internal Medicine Cardiology, Baldingerstrasse, D 35033 Marburg, Germany
    Eur J Heart Fail 9:98-9. 2007
    ..To our knowledge, combined occurrence of non-compaction cardiomyopathy, skeletal myopathy and hereditary spherocytosis has not previously been reported...
  72. ncbi request reprint Activated nuclear transcription factor kappaB in patients with myocarditis and dilated cardiomyopathy--relation to inflammation and cardiac function
    Peter Alter
    Philipps University of Marburg, Department of Internal Medicine Cardiology, Germany
    Biochem Biophys Res Commun 339:180-7. 2006
    ..The latter also applies to the course of autoimmune myocarditis. One principal candidate for an adverse remodeling is nuclear factor-kappaB (NFkappaB)...
  73. ncbi request reprint TNF-related apoptosis-inducing ligand and its decoy receptor osteoprotegerin in nonischemic dilated cardiomyopathy
    Michael Schoppet
    Department of Internal Medicine and Cardiology, Philipps University, D 35033 Marburg, Germany
    Biochem Biophys Res Commun 338:1745-50. 2005
    ..001 vs. controls). In conclusion, myocardial overexpression of antiapoptotic OPG in DCM patients may represent a compensatory mechanism to limit systemic activation of TRAIL in patients with congestive heart disease...
  74. ncbi request reprint [Diagnosis and treatment of inflammatory heart diseases: role of endomyocardial biopsy]
    Sabine Pankuweit
    Klinik fur Kardiologie, Universitätsklinikum GmbH Giessen und Marburg, Standort Marburg, Marburg
    Herz 31:361-5. 2006
  75. ncbi request reprint Biventricular stimulation to prevent cardiac desynchronization: rationale, design, and endpoints of the 'Biventricular Pacing for Atrioventricular Block to Prevent Cardiac Desynchronization (BioPace)' study
    Reinhard C Funck
    Department of Cardiology and Angiology, Clinic of Internal Medicine and Cardiology, University Hospital Philipps University Marburg, Baldingerstr 1, D 35033 Marburg, Germany
    Europace 8:629-35. 2006
    ..Secondary endpoints are QoL and the 6-MHW result at 12 months after implantation, hospitalization rate, LV dimensions, LV ejection fraction, and the development of chronic AF and other adverse events...
  76. ncbi request reprint Gene symbol: MYBPC3. Disease: Cardiomyopathy, hypertrophic
    Volker Ruppert
    Philipps Universitat Marburg, Innere Medizin, Kardiologie, Hans Meerwein Strasse, 1, 35043 Marburg, Germany
    Hum Genet 124:314. 2008
  77. ncbi request reprint Depression of heart rate variability in patients with increased ventricular wall stress
    Peter Alter
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Gremany
    Pacing Clin Electrophysiol 32:S26-31. 2009
    ..Depression of HRV is related to several hemodynamic parameters. We hypothesized that an increased left ventricular (LV) wall stress is related to a depressed HRV in patients with LV dilatation or dysfunction...
  78. ncbi request reprint Sleep-disordered breathing in recipients of implantable defibrillators
    Wolfram Grimm
    Department of Cardiology, University of Marburg and Giessen, Marburg, Germany
    Pacing Clin Electrophysiol 32:S8-11. 2009
    ..To examine the prevalence and clinical significance of sleep-disordered breathing in patients with implantable cardioverter defibrillators (ICD)...
  79. doi request reprint [Familial predisposition and microbial etiology in dilated cardiomyopathy]
    Sabine Pankuweit
    Klinik für Innere Medizin Kardiologie, Philipps Universitat Marburg, Baldingerstrasse, 35043 Marburg, Germany
    Herz 34:110-6. 2009
    ..A possible family history including a pedigree should be ascertained and with regard to a possible inflammatory or viral heart disease, endomyocardial biopsies should be investigated by polymerase chain reaction and immunohistochemistry...
  80. ncbi request reprint ["Why is it always the heart which suffers from myocardial infarction?" The "Marburg hypothesis" of the pathogenesis of atherosclerosis]
    In Frau Susanne Memoriam Klumpp
    Zentrum Innere Medizin Kardiologie, Universitätsklinikum Giessen Marburg, Philipps Universitat Marburg, Marburg, Germany
    Herz 35:192-7. 2010
    ..Finding mechanisms to reduce the presence of fatty acids within the arterial wall might prevent plaque destabilization and could be a potential target in our fight against atherosclerosis...
  81. doi request reprint Activation of STAT1 transcription factor precedes up-regulation of coxsackievirus-adenovirus receptor during viral myocarditis
    Volker Ruppert
    Department of Cardiology, University of Marburg, Marburg, Germany
    Cardiovasc Pathol 17:81-92. 2008
    ....
  82. doi request reprint Evaluation and management of pericardial effusion in patients with neoplastic disease
    Bernhard Maisch
    Department of Internal Medicine and Cardiology, UKGM GmbH Giessen and Marburg, Marburg Heart Center and Faculty of Medicine, Philipps University, Marburg, Germany
    Prog Cardiovasc Dis 53:157-63. 2010
    ..Recurrence of pericardial effusion was prevented for at least 3 months in more than 85% of patients. This differential diagnostic approach and the results of treatment were compared with published series...
  83. doi request reprint HLA-DQB1* polymorphism and associations with dilated cardiomyopathy, inflammatory dilated cardiomyopathy and myocarditis
    Irene Portig
    Department of Internal Medicine Cardiology, Philipps University Marburg, Marburg, Germany
    Autoimmunity 42:33-40. 2009
    ....
  84. ncbi request reprint Monitoring of functional plasminogen in the blood of patients on fibrinolytics
    Thomas W Stief
    Department of Laboratory Medicine, Hospital of Philipps University, Marburg, Germany
    Clin Appl Thromb Hemost 15:297-308. 2009
    ..The present findings support the profibrinolytic action of chloramines...
  85. ncbi request reprint Separation of large mammalian ventricular myosin differing in ATPase activity
    Heinz Rupp
    Molecular Cardiology Laboratory, Department of Internal Medicine and Cardiology, Philipps University of Marburg, Karl von Frisch Strasse 1, 35033 Marburg, Germany
    Can J Physiol Pharmacol 85:326-31. 2007
    ..The data demonstrate a heterogeneity of large mammalian ventricular myosin, whereby an increased cardiac load appeared to be associated with a higher myosin VA proportion that exhibited a reduced ATPase activity...
  86. ncbi request reprint [Heart insufficiency--what is it?]
    Bernhard Maisch
    Klinik für Innere Medizin Kardiologie, Philipps Universitat, Marburg, Germany
    Herz 31:270-2. 2006
  87. ncbi request reprint Different profile of antioxidative capacity results in pulmonary dysfunction and amplified inflammatory response After CABG surgery
    Sebastian Vogt
    Heart Surgery, Internal Medicine, Philipps University, Marburg, Germany
    J Surg Res 139:136-42. 2007
    ..The present study addresses the question for group-specific release of radical oxygen species (ROS) by extracorporeal circulation (ECC) with emphasis on pulmonary function...
  88. ncbi request reprint Antitachycardia pacing for spontaneous rapid ventricular tachycardia in patients with prophylactic cardioverter-defibrillator therapy
    Wolfram Grimm
    Department of Cardiology, Hospital of the Philipps University of Marburg, Marburg, Germany
    Pacing Clin Electrophysiol 29:759-64. 2006
    ..This study investigated the efficacy of empirical ATP to terminate rapid ventricular tachycardia (VT) in heart failure patients with prophylactic ICD therapy...
  89. doi request reprint Athlete's heart or hypertrophic cardiomyopathy?
    Jörg Lauschke
    Department of Internal Medicine and Cardiology, Philipps Universitat Marburg, Marburg, Germany
    Clin Res Cardiol 98:80-8. 2009
    ..On the other hand sportsmen with an athlete's heart are reassured and able to continue as competitors. New insights into electrophysiological changes during physiological hypertrophy could probably change this view...
  90. ncbi request reprint Usefulness of cytokines interleukin-6 and interleukin-2R concentrations in diagnosing active infective endocarditis involving native valves
    Peter Alter
    Department of Internal Medicine Cardiology, Philipps University of Marburg, Marburg, Germany
    Am J Cardiol 89:1400-4. 2002
    ..Assessment of IL-6 and IL-2R could thus provide new diagnostic criteria for inflammation in IE, and these interleukins could also be suitable for monitoring the course of inflammation during treatment...
  91. ncbi request reprint Detection of anti-hsp70 immunoglobulin G antibodies indicates better outcome in coronary artery bypass grafting patients suffering from severe preoperative angina
    Sebastian Vogt
    Department of Cardiovascular Surgery, Philipps University Hospital, Marburg, Germany
    Ann Thorac Surg 78:883-9; discussion 889. 2004
    ..We correlated these clinical findings with the presence of antibodies against hsp70 and the antioxidative capacity of patients' sera...
  92. ncbi request reprint Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Mönckeberg's sclerosis and atherosclerosis
    Michael Schoppet
    Department of Internal Medicine, Philipps University, Baldingerstrasse, D 35033 Marburg, Germany
    J Clin Endocrinol Metab 89:4104-12. 2004
    ....
  93. ncbi request reprint Arrhythmia risk stratification with regard to prophylactic implantable defibrillator therapy in patients with dilated cardiomyopathy. Results of MACAS, DEFINITE, and SCD-HeFT
    Wolfram Grimm
    Department of Internal Medicine and Cardiology, Hospital of the Philipps University, Marburg, Germany
    Herz 29:348-52. 2004
    ..SCD-HeFT showed a significant reduction of total mortality in the ICD group, whereas amiodarone did not improve survival...
  94. ncbi request reprint A new but frequent mutation of apoB-100-apoB His3543Tyr
    Muhidien Soufi
    Department of Internal Medicine Cardiology, Philipps University, Marburg, Germany
    Atherosclerosis 174:11-6. 2004
    ..47% compared to 0.12% for the known Arg 3500 Gln (R3500Q) mutation. In conclusion, the new mutation is four times more frequent than "classical" FDB and thus appears to be the most common apoB mutation in Germany...
  95. ncbi request reprint Novel point mutations in the mitochondrial DNA detected in patients with dilated cardiomyopathy by screening the whole mitochondrial genome
    Volker Ruppert
    Department of Internal Medicine and Cardiology, Philipps University Marburg, Marburg, Germany
    Biochem Biophys Res Commun 318:535-43. 2004
    ..6% of patients as well as in 9.7% of controls. Thus, mutations altering the function of the enzyme subunits of the respiratory chain can be relevant for the pathogenesis of dilated cardiomyopathy...
  96. ncbi request reprint [Excessive hyperchylomicronemia--a rare cause of acute retrosternal and epigastric pain in pregnancy]
    Alexander M Sattler
    Klinik für Innere Medizin Kardiologie, Klinikum der Philipps Universität, Marburg
    Herz 28:257-61. 2003
    ..Triglycerides decreased to 6,600 mg/dl at this session. Keeping to a low-fat diet (< 30 g fat per day), the patient remained healthy and completed pregnancy with the delivery of a healthy girl in her 39th week of pregnancy...
  97. ncbi request reprint Noninvasive arrhythmia risk stratification in idiopathic dilated cardiomyopathy: results of the Marburg Cardiomyopathy Study
    Wolfram Grimm
    Department of Cardiology, Philipps University Marburg, Baldingerstrasse, 35033 Marburg, Germany
    Circulation 108:2883-91. 2003
    ..Arrhythmia risk stratification with regard to prophylactic implantable cardioverter-defibrillator therapy is a completely unsolved issue in idiopathic dilated cardiomyopathy (IDC)...
  98. ncbi request reprint Prognostic significance of morphometric endomyocardial biopsy analysis in patients with idiopathic dilated cardiomyopathy
    Wolfram Grimm
    Department of Cardiology, Hospital of the Philipps University of Marburg, Marburg, Germany
    Am Heart J 146:372-6. 2003
    ..To date, considerable controversy exists on the prognostic significance of morphometric endomyocardial biopsy findings in patients with idiopathic dilated cardiomyopathy (IDC)...
  99. ncbi request reprint Prognostic significance of heart rate turbulence following ventricular premature beats in patients with idiopathic dilated cardiomyopathy
    Wolfram Grimm
    Department of Cardiology, Hospital of the Philipps University of Marburg, Marburg, Germany
    J Cardiovasc Electrophysiol 14:819-24. 2003
    ..Heart Rate Turbulence in Dilated Cardiomyopathy...
  100. ncbi request reprint Heart rate turbulence following ventricular premature beats in healthy controls
    Wolfram Grimm
    Department of Cardiology, Munich University of Technology, Germany
    Ann Noninvasive Electrocardiol 8:127-31. 2003
    ....
  101. ncbi request reprint How many patients with dilated cardiomyopathy may potentially benefit from cardiac resynchronization therapy?
    Wolfram Grimm
    Department of Cardiology, Hospital of the Philipps University of Marburg, Baldingerstrasse, 35033 Marburg, Germany
    Pacing Clin Electrophysiol 26:155-7. 2003
    ..Thus, between 7% and 14% of patients with DCM were candidates for CRT depending on the application of strict versus less restrictive selection criteria...