Research Topics
| P LangerSummaryAffiliation: Philipps University Country: Germany Publications
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Detail Information
Publications
Five years of prospective screening of high-risk individuals from families with familial pancreatic cancerP Langer
Department of General Surgery, Philipps University Marburg, Germany
Gut 58:1410-8. 2009..Familial pancreatic cancer (FPC) accounts for approximately 3% of all pancreatic cancer (PC) cases. It has been suggested that high-risk individuals (HRIs) should be offered a screening programme...
Adrenal involvement in multiple endocrine neoplasia type 1: results of 7 years prospective screeningJ Waldmann
Department of General Surgery, Philipps University, Marburg, Germany
Langenbecks Arch Surg 392:437-43. 2007..Prevalence in recent studies varies between 9 and 45%. A genotype-phenotype correlation has been described as well as the development of adrenocortical carcinomas. Long-term prospective data are still lacking...- Management of sporadic and multiple endocrine neoplasia type 1 gastrinomasV Fendrich
Department of Surgery, Philipps University Marburg, Marburg, Bielefeld, Germany
Br J Surg 94:1331-41. 2007..Gastrinomas are functional endocrine duodenopancreatic tumours and are responsible for Zollinger-Ellison syndrome (ZES). Clinical presentation, localization techniques and operative management were reviewed... - Multiple primaries in pancreatic cancer patients: indicator of a genetic predisposition?B Gerdes
Department of General Surgery, Philipps University of Marburg, D 35033 Marburg, Germany
Int J Epidemiol 29:999-1003. 2000..To evaluate inherited predisposition in pancreatic cancer we compared the clinical data of pancreatic cancer patients with and without multiple primaries as well as the frequency of malignancies among their relatives... - Prospective controlled trial of a standardized meal stimulation test in the detection of pancreaticoduodenal endocrine tumours in patients with multiple endocrine neoplasia type 1P Langer
Department of General Surgery, Philipps-University, Marburg, Germany
Br J Surg 88:1403-7. 2001..The expensive and time-consuming meal test can be excluded from MEN 1 screening programmes... - Prevalence of multiple endocrine neoplasia type 1 in young patients with apparently sporadic primary hyperparathyroidism or pancreaticoduodenal endocrine tumoursP Langer
Department of General Surgery, Philipps University Marburg, Marburg, Germany
Br J Surg 90:1599-603. 2003..CONCLUSION: Sporadic pHPT due to multiglandular disease in patients younger than 40 years may represent the first organ manifestation of MEN1 despite a negative family history... - Multiple small "imaging" branch-duct type intraductal papillary mucinous neoplasms (IPMNs) in familial pancreatic cancer: indicator for concomitant high grade pancreatic intraepithelial neoplasia?D K Bartsch
Department of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Baldingerstrasse, 35033, Marburg, Germany
Fam Cancer 12:89-96. 2013..In the setting of FPC, the presence of multiple small "imaging" BD-IPMNs may indicate the presence of high-grade PanIN lesions elsewhere in the pancreas... - Adrenocortical carcinoma--our experience with 11 casesP Langer
Department of General Surgery, Philipps University Marburg, Germany
Langenbecks Arch Surg 385:393-7. 2000..5-2 cases per million per year. Diagnosis is mostly delayed and prognosis is poor. We report our experiences with 11 patients operated on within the last 10 years... - Harmonic scalpel versus conventional dissection technique in pylorus-preserving partial duodenopancreatectomyA E Heverhagen
Department of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Marburg, Germany
Dig Surg 29:420-5. 2012..The aim of our study was to evaluate the feasibility and safety of the ultrasonic dissection device in pylorus-preserving duodenopancreatectomy (PPPD)... - Clinical background is required for optimum performance with a VR laparoscopy simulatorI Hassan
Department of Surgery, Philipps University Marburg, Germany
Comput Aided Surg 11:103-6. 2006..To determine the role of clinical background when assessing the learning effect using a virtual-reality (VR) laparoscopy simulator (LapSim)... - Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumorsE P Slater
Department of Surgery, Philipps University Marburg, Germany
Eur J Endocrinol 154:587-98. 2006..The comparative analysis by cDNA microarrays of gene-expression patterns of benign and malignant adrenocortical tumors allows us to identify new tumor-suppressor genes and proto-oncogenes underlying adrenocortical tumorigenesis... - A novel insulinoma tumor suppressor gene locus on chromosome 22q with potential prognostic implicationsA Wild
Department of General Surgery, Philipps University of Marburg, D 35043 Marburg, Germany
J Clin Endocrinol Metab 86:5782-7. 2001..The distinct pattern of allelic loss identified in this chromosomal region appears to be an attractive candidate marker for further evaluation with regard to the discrimination between benign and malignant insulinomas... - Familial ACTH-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia clinically affecting only female family membersC Nies
Department of General Surgery, Klinik für Visceral, Thorax und Gefässchirurgue, Philipps University Marburg, Germany
Exp Clin Endocrinol Diabetes 110:277-83. 2002.... - Short-term preoperative radiotherapy in rectal cancer patients leads to a reduction of the detectable number of lymph nodes in resection specimensK Maschuw
Department of General Surgery, Philipps-University of Marburg, Baldingerstrasse, 35033, Marburg, Germany
Langenbecks Arch Surg 391:364-8. 2006..This might influence the required number of lymph nodes in current staging systems for rectal cancer in the future...