Research Topics
Genomes and Genes | L KonradSummaryAffiliation: Philipps University Country: Germany Publications
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Publications
Mesenchymal entactin-1 (nidogen-1) is required for adhesion of peritubular cells of the rat testis in vitroL Konrad
Department of Anatomy and Cell Biology, Philipps Universitat Marburg, Germany
Eur J Cell Biol 79:112-20. 2000..From these data we conclude that entactin-1 is exclusively produced and secreted by mesenchymal peritubular cells, and affects adhesion of peritubular cells in an autocrine manner...
Transforming growth factor-beta2 mediates mesenchymal-epithelial interactions of testicular somatic cellsL Konrad
Department of Anatomy and Cell Biology, Philipps University, Marburg, Germany
Endocrinology 141:3679-86. 2000....
Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extractL Konrad
Department of Anatomy and Cell Biology, Philipps Universitat Marburg, Germany
Planta Med 66:44-7. 2000..The antiproliferative effect of ME-20 of stinging nettle roots observed both in an in vivo model and in an in vitro system clearly indicates a biologically relevant effect of compounds present in the extract...
Expression and enzymic activity of ecto 5'-nucleotidase in the human male genital tractL Konrad
Department of Anatomy and Cell Biology, Philipps Universitat, Marburg, Germany
Biol Reprod 59:190-6. 1998..4 kilobases. The relatively strong expression of 5'-NT in the human male accessory sex glands points to a potential regulatory role of the enzyme during posttesticular modification of the sperm surface...
Calcyclin is differentially expressed in rat testicular cellsL Konrad
Department of Anatomy and Cell Biology, Philipps University, Marburg, Germany
Biochim Biophys Acta 1489:440-4. 1999..Our findings point to a paracrine regulation of calcyclin expression in testicular peritubular fibroblasts which seems to be related to tubular growth...
Antiproliferative effect of a polysaccharide fraction of a 20% methanolic extract of stinging nettle roots upon epithelial cells of the human prostate (LNCaP)J J Lichius
Department of Pharmaceutical Biology, Philipps University, Marburg, Germany
Pharmazie 54:768-71. 1999..No cytotoxic effect of POLY-M on cell proliferation was observed. The in vitro results show for the first time an antiproliferative effect of Urtica compounds on human prostatic epithelium and confirm our previous in vivo findings...
Effects of dexamethasone on proliferation of and fibronectin synthesis by human primary prostatic stromal cells in vitroM Albrecht
Department of Anatomy and Cell Biology, Philipps University, Marburg, Germany
Andrologia 34:11-21. 2002..The authors assume that locally accumulating glucocorticoids can also influence the regulation of cell growth and extracellular matrix synthesis in the human prostate in vivo and may play a role in the pathologically altered prostate...
The role of apocrine released proteins in the post-testicular regulation of human sperm functionG Aumuller
Department of Anatomy and Cell Biology, Philipps Universitat, Marburg, Germany
Adv Exp Med Biol 424:193-219. 1997..Incubation of spermatozoa with seminosomes and the respective purified antiserum had no effect on sperm motility. This is in contradistinction to former reports on motility increase induced by the so-called prostasomes...
Glucocorticoid receptor distribution in rat testis during postnatal development and effects of dexamethasone on immature peritubular cells in vitroM A Weber
Department of Anatomy and Cell Biology, University of Marburg, Germany
Andrologia 32:23-30. 2000..In summary, labelling of germ cells, especially in immature rats, might indicate an inhibition of spermatogenesis by corticosteroids...
Dihydroorotate dehydrogenase mRNA and protein expression analysis in normal and drug-resistant cellsM Loffler
Institute for Physiological Chemistry, Philipps University Marburg, Marburg, Germany
Nucleosides Nucleotides Nucleic Acids 23:1281-5. 2004..In mouse B-lymphocytes, which were adapted to tolerate up to a 50-fold concentration of the DHODH inhibitor leflunomide, a 20 fold protein overexpression was measured. Southern blotting indicated DHODH gene amplification...
Immunohistochemistry and in situ hybridization of the androgen receptor in the developing human prostateG Aumuller
Department of Anatomy and Cell Biology, Marburg, Germany
Anat Embryol (Berl) 197:199-208. 1998....
Post-natal development of the rat testis: steroid hormone receptor distribution and extracellular matrix depositionM A Weber
Division of Oncological Diagnostics and Therapy, German Cancer Research Centre, Heidelberg
Andrologia 34:41-54. 2002....
VDAC2 (porin-2) expression pattern and localization in the bovine testisK D Hinsch
Department of Dermatology and Andrology, Justus Liebig University, Gaffkystr 14, D 35392, Giessen, Germany
Biochim Biophys Acta 1518:329-33. 2001..In contrast, VDAC1 (porin-1) is exclusively localized in Sertoli cells. The possible role of testicular VDAC2 in providing energy metabolites and in germ cell apoptosis is discussed...
Effects of TGF-betas and a specific antagonist on apoptosis of immature rat male germ cells in vitroL Konrad
Department of Urology, Medical Faculty, 35033 Marburg, Germany
Apoptosis 11:739-48. 2006....
Localization and synthesis of zona pellucida proteins in the marmoset monkey (Callithrix jacchus) ovaryK Bogner
Center of Dermatology and Andrology, University of Giessen, Gaffkystr. 14, D-35392 Giessen, Germany
Mol Hum Reprod 10:481-8. 2004....
The influence of bone allograft processing on osteoblast attachment and functionA Hofmann
Department of Trauma Surgery, Johannes Gutenberg University School of Medicine, Langenbeckstr 1, Mainz D 55101, Germany
J Orthop Res 23:846-54. 2005..Therefore, processing-related alterations of BMSC-function may be important for the success of bone grafting. The experimental setup used in the present work may be useful for further optimisation of bone allograft processing...
Cloning, structure, cellular localization, and possible function of the tumor suppressor gene lethal(3)malignant blood neoplasm-1 of Drosophila melanogasterL Konrad
Institut fur Genetik, Johannes Gutenberg Universitat, Mainz, Federal Republic of Germany
Dev Biol 163:98-111. 1994..Homologies of the G-S-rich C-terminus of the putative MBN83 protein to human cytokeratins K1, K10, and mouse loricrin were found. The structure and possible function of the wild-type l(3)mbn-1+ gene are discussed...
