- TRPM5, a taste-signaling transient receptor potential ion-channel, is a ubiquitous signaling component in chemosensory cellsSilke Kaske
Philipps University Marburg, Institute of Pharmacology and Toxicology, Marburg, Germany
BMC Neurosci 8:49. 2007..TRPM5 is known to be abundantly expressed in taste receptor cells where it participates in sweet, amino acid and bitter perception. A role of TRPM5 in other sensory systems, however, has not been studied so far...
- Hypomagnesemia with secondary hypocalcemia due to a missense mutation in the putative pore-forming region of TRPM6Vladimir Chubanov
Institute for Pharmacology and Toxicology, Philipps University Marburg, Karl von Frisch Strasse 1, 35033 Marburg, Germany
J Biol Chem 282:7656-67. 2007..We conclude that a functional defect in the putative pore of TRPM6/7 channel complexes is sufficient to impair body magnesium homeostasis...