Research Topics
| Bernhard KadenbachSummaryAffiliation: Philipps University Country: Germany Publications
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Detail Information
Publications
Degenerative diseases, oxidative stress and cytochrome c oxidase functionBernhard Kadenbach
Fachbereich Chemie, Philipps University, D 35032 Marburg, Germany
Trends Mol Med 15:139-47. 2009..This mechanism is proposed to represent a missing molecular link between stress and degenerative diseases...
High efficiency versus maximal performance--the cause of oxidative stress in eukaryotes: a hypothesisBernhard Kadenbach
Department of Chemistry, Philipps University, D 35032 Marburg, Germany
Mitochondrion 13:1-6. 2013..We conclude that 'oxidative stress' occurs when the control of COX activity by the [ATP]/[ADP] ratio is switched off via neural signals...
Introduction to mitochondrial oxidative phosphorylationBernhard Kadenbach
Philipps University Marburg, Marburg, Germany
Adv Exp Med Biol 748:1-11. 2012....
The role of mitochondrial membrane potential in ischemic heart failureBernhard Kadenbach
Fachbereich Chemie, Philipps Universitaet, D 35032 Marburg, Germany
Mitochondrion 11:700-6. 2011..Ischemic preconditioning is suggested to cause additional phosphorylation of CcO, protecting the enzyme from immediate dephosphorylation via ROS signaling...
New extension of the Mitchell Theory for oxidative phosphorylation in mitochondria of living organismsBernhard Kadenbach
Fachbereich Chemie, Cardiovascular Laboratory, Philipps University, D 35032 Marburg, Germany
Biochim Biophys Acta 1800:205-12. 2010....
Intrinsic and extrinsic uncoupling of oxidative phosphorylationBernhard Kadenbach
Fachbereich Chemie, Philipps Universitat, Hans Meerwein Strasse, D 35032 Marburg, Germany
Biochim Biophys Acta 1604:77-94. 2003..Finally, the regulation of DeltaPsi and the production of reactive oxygen species (ROS) in mitochondria at high DeltaPsi values (150-200 mV) are discussed...
Individual biochemical behaviour versus biological robustness: spotlight on the regulation of cytochrome c oxidaseRabia Ramzan
Philipps University, Marburg, Germany
Adv Exp Med Biol 748:265-81. 2012....
The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseasesBernhard Kadenbach
Fachbereich Chemie, Philipps Universitat, Hans Meerwein Strasse, D 35032 Marburg, Germany
Biochim Biophys Acta 1655:400-8. 2004..Consequently, energy metabolism changes to an excited state. We propose that this change causes an increase in DeltaPsi(m), a condition for the formation of ROS and induction of apoptosis...
Mitochondrial respiration and membrane potential are regulated by the allosteric ATP-inhibition of cytochrome c oxidaseRabia Ramzan
Biomedical Research Center, Cardiovascular Laboratory, Philipps University, D 35032 Marburg, Germany
Biochim Biophys Acta 1797:1672-80. 2010..quot; Only when the allosteric ATP-inhibition is switched off under stress, respiration is regulated by "respiratory control," based on DeltaPsi(m) according to the Mitchell Theory...
Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidaseIcksoo Lee
Fachereich Chemie, Philipps-University, Marburg, Germany
Mol Cell Biochem 234:63-70. 2002....
