Walter Hundt

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Effect of continuous high intensity focused ultrasound in a squamous cell carcinoma tumor model compared to muscle tissue evaluated by MRI, histology, and gene expression
    Walter Hundt
    Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, California 94305 5488, USA
    Technol Cancer Res Treat 8:85-98. 2009
  2. ncbi request reprint Detection of micrometastases of squamous cell carcinoma tumor cells in muscle tissue
    Silke Steinbach
    Department of Radiology, Philipps University Marburg, Germany
    Anticancer Res 33:5213-21. 2013
  3. doi request reprint Combined treatment of subacute and acute synthetic and venous bypass-graft occlusions with percutaneous mechanical thrombectomy and thrombolysis
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Germany Electronic address
    Eur J Radiol 82:e807-15. 2013
  4. doi request reprint Use of in vivo bioluminescence and MRI to determine hyperthermia-induced changes in luciferase activity under the control of an hsp70 promoter
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA, USA
    NMR Biomed 25:1378-91. 2012
  5. ncbi request reprint Imaging of firefly luciferase activity under antiangiogenic therapy in a heat shock protein 70-transfected melanoma tumor model
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Marburg, Germany
    Mol Imaging 12:129-36. 2013
  6. doi request reprint Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor model
    Walter Hundt
    Stanford School of Medicine, Lucas MRS Research Center, Department of Radiology, Stanford, California, USA
    J Biomed Opt 17:065001. 2012
  7. doi request reprint In vivo monitoring of antiangiogenic therapy by magnetic resonance and bioluminescence imaging in an M21 tumor model through activation of an hsp70 promoter-luciferase reporter construct
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Contrast Media Mol Imaging 7:450-9. 2012
  8. doi request reprint Novel approach to complex pulmonary arteriovenous malformation embolization using detachable coils and Amplatzer vascular plugs
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Baldingerstrasse 35043, Marburg, Germany
    Eur J Radiol 81:e732-8. 2012
  9. doi request reprint Gene expression analysis of SCC tumor cells in muscle tissue
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Marburg, Germany
    Eur Arch Otorhinolaryngol 269:1653-63. 2012
  10. doi request reprint Evaluation of contrast medium enhancement and [(18)F]-FDG uptake of liver metastasis in PET/CT prior to therapy
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Baldingerstrasse, D 35043 Marburg, Germany
    Eur J Radiol 81:652-7. 2012

Detail Information

Publications22

  1. ncbi request reprint Effect of continuous high intensity focused ultrasound in a squamous cell carcinoma tumor model compared to muscle tissue evaluated by MRI, histology, and gene expression
    Walter Hundt
    Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, California 94305 5488, USA
    Technol Cancer Res Treat 8:85-98. 2009
    ..The use of HIFU treatment on tumor and muscle tissue results in dramatic changes in gene expression. The expression of some genes are tissue specific, the expression of other genes are independent of the tissue type...
  2. ncbi request reprint Detection of micrometastases of squamous cell carcinoma tumor cells in muscle tissue
    Silke Steinbach
    Department of Radiology, Philipps University Marburg, Germany
    Anticancer Res 33:5213-21. 2013
    ..Significant differences in gene expression between micrometastases in muscle tissue and pure muscle tissue were found. The genes found to be up-regulated could be used to detect micrometastases in muscle tissue. ..
  3. doi request reprint Combined treatment of subacute and acute synthetic and venous bypass-graft occlusions with percutaneous mechanical thrombectomy and thrombolysis
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Germany Electronic address
    Eur J Radiol 82:e807-15. 2013
    ..The aim of this retrospective study was to compare the combined treatment of PMT and local thrombolysis with thrombolysis therapy alone...
  4. doi request reprint Use of in vivo bioluminescence and MRI to determine hyperthermia-induced changes in luciferase activity under the control of an hsp70 promoter
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA, USA
    NMR Biomed 25:1378-91. 2012
    ..The major finding of the present study was that heat-related biochemical changes in tumor tissue can be determined by MRI...
  5. ncbi request reprint Imaging of firefly luciferase activity under antiangiogenic therapy in a heat shock protein 70-transfected melanoma tumor model
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Marburg, Germany
    Mol Imaging 12:129-36. 2013
    ..Targeted antiangiogenic therapy can induce luciferase activity where transcription is controlled by an hsp70 promoter and HSP70 protein in melanoma tumors...
  6. doi request reprint Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor model
    Walter Hundt
    Stanford School of Medicine, Lucas MRS Research Center, Department of Radiology, Stanford, California, USA
    J Biomed Opt 17:065001. 2012
    ..Thus, targeted antiangiogenic therapy can induce Hsp70 expression and HSP70 protein in melanoma tumors...
  7. doi request reprint In vivo monitoring of antiangiogenic therapy by magnetic resonance and bioluminescence imaging in an M21 tumor model through activation of an hsp70 promoter-luciferase reporter construct
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Contrast Media Mol Imaging 7:450-9. 2012
    ..Moreover, MRI showed a significant reduction of the contrast medium uptake parameters and an increase in the diffusion coefficient of the tumors...
  8. doi request reprint Novel approach to complex pulmonary arteriovenous malformation embolization using detachable coils and Amplatzer vascular plugs
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Baldingerstrasse 35043, Marburg, Germany
    Eur J Radiol 81:e732-8. 2012
    ....
  9. doi request reprint Gene expression analysis of SCC tumor cells in muscle tissue
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Marburg, Germany
    Eur Arch Otorhinolaryngol 269:1653-63. 2012
    ..Gene expression analysis revealed changes in the expression levels of SCCVII cells in muscle tissue in 220 genes. Significant gene expression differences between SCCVII cells in muscle tissue and pure muscle tissue could be seen...
  10. doi request reprint Evaluation of contrast medium enhancement and [(18)F]-FDG uptake of liver metastasis in PET/CT prior to therapy
    Walter Hundt
    Department of Radiology, Philipps University Marburg, Baldingerstrasse, D 35043 Marburg, Germany
    Eur J Radiol 81:652-7. 2012
    ..To evaluate the contrast medium enhancement and [(18)F]-FDG uptake of liver metastases in patients suffering from colon or breast carcinoma prior to therapy...
  11. ncbi request reprint Induction of luciferase activity under the control of an hsp70 promoter using high-intensity focused ultrasound: combination of bioluminescence and MRI imaging in three different tumour models
    W Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Technol Cancer Res Treat 10:197-210. 2011
    ....
  12. doi request reprint Modulation of luciferase activity using high intensity focused ultrasound in combination with bioluminescence imaging, magnetic resonance imaging and histological analysis in muscle tissue
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Ultrasonics 49:549-57. 2009
    ..9 W/cm2 and 802.0 W/cm2 14.1 +/- 3.6 x 10(6) photon/s (6.1 +/- 1.5-fold), respectively, 5.1 +/- 4.7 x 10(6) photon/s (6.5 +/- 2.0-fold). HIFU can enhance the luciferase activity controlled by a CMV-promoter...
  13. doi request reprint The effect of high intensity focused ultrasound on luciferase activity on two tumor cell lines in vitro, under the control of a CMV promoter
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Ultrasonics 49:312-8. 2009
    ..Our findings demonstrate that HIFU can enhance the luciferase activity controlled by a CMV promoter. However it also has a higher damaging effect on the cells...
  14. doi request reprint Comparison of continuous vs. pulsed focused ultrasound in treated muscle tissue as evaluated by magnetic resonance imaging, histological analysis, and microarray analysis
    Walter Hundt
    Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305 5488, USA
    Eur Radiol 18:993-1004. 2008
    ....
  15. ncbi request reprint In vitro effect of focused ultrasound or thermal stress on HSP70 expression and cell viability in three tumor cell lines
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA, USA
    Acad Radiol 14:859-70. 2007
    ..In this study, we compared the effect of focused ultrasound with the effect of thermal stress on the induction of a heat inducible promoter in an in vitro model using three tumor cell lines (M21, SCCVII, and NIH3T3)...
  16. ncbi request reprint Gene expression profiles, histologic analysis, and imaging of squamous cell carcinoma model treated with focused ultrasound beams
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    AJR Am J Roentgenol 189:726-36. 2007
    ....
  17. doi request reprint Tumor tissue characterization evaluating the luciferase activity under the control of a hsp70 promoter and MR imaging in three tumor cell lines
    Walter Hundt
    Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
    Eur J Radiol 70:369-77. 2009
    ..The combination of MR imaging with bioluminescence imaging improves the characterization of tumor tissue giving better information of this tissue on the molecular level...
  18. doi request reprint Mechanic effect of pulsed focused ultrasound in tumor and muscle tissue evaluated by MRI, histology, and microarray analysis
    Walter Hundt
    Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305 5488, USA
    Eur J Radiol 76:279-87. 2010
    ..Pulsed HIFU treatment on tumor and muscle tissue results in dramatic changes in gene expression, indicating that the effect of pulsed HIFU is in some regard dependent and also independent of the tissue type...
  19. doi request reprint Low flow vascular malformations of the head and neck: a study on brightness mode, color coded duplex and spectral Doppler sonography
    Behfar Eivazi
    Division of Angiology, Department of Otolaryngology, Head and Neck Surgery, University of Marburg, Deutschhausstr 3, 35037 Marburg, Germany
    Eur Arch Otorhinolaryngol 268:1505-11. 2011
    ..When considering differentiating among LFVM, features such as the echogenecity, spectral Doppler wave forms, and the evidence of phleboliths contribute to establish the correct diagnosis...
  20. doi request reprint Does hereditary hemorrhagic telangiectasia affect olfactory or gustatory function?
    Silke Steinbach
    Department of Otorhinolaryngology, Philipps University, Marburg, Germany
    Am J Rhinol Allergy 26:463-8. 2012
    ..Disorders of the nasal/oral cavity may interfere with the olfactory and gustatory functions. Fifty-four HHT patients were investigated by smell/taste tests...
  21. pmc Smell and taste in inflammatory bowel disease
    Silke Steinbach
    Department of Otorhinolaryngology, Philipps University, Marburg, Germany
    PLoS ONE 8:e73454. 2013
    ..To investigate the olfactory/gustatory functions of patients with inflammatory bowel disease (IBD) by smell/taste tests, and to determine if disease activity or medication might influence the olfactory/gustatory functions of patients...
  22. doi request reprint Effect of platinum-containing chemotherapy on olfactory, gustatory, and hearing function in ovarian cancer patients
    Silke Steinbach
    Department of Otorhinolaryngology, Philipps University, Baldingerstrasse, 35033 Marburg, Germany
    Arch Gynecol Obstet 286:473-80. 2012
    ..Therefore, one of the main therapeutic aims after cytoreductive surgery for these patients is to identify, delay and relieve chemotherapy-induced side effects and optimise the quality of life, especially after first-line therapy...