Research Topics
| Walter HundtSummaryAffiliation: Philipps University Country: Germany Publications
|
Detail Information
Publications
Effect of continuous high intensity focused ultrasound in a squamous cell carcinoma tumor model compared to muscle tissue evaluated by MRI, histology, and gene expressionWalter Hundt
Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, California 94305 5488, USA
Technol Cancer Res Treat 8:85-98. 2009..The use of HIFU treatment on tumor and muscle tissue results in dramatic changes in gene expression. The expression of some genes are tissue specific, the expression of other genes are independent of the tissue type...
Imaging of firefly luciferase activity under antiangiogenic therapy in a heat shock protein 70-transfected melanoma tumor modelWalter Hundt
Department of Radiology, Philipps University Marburg, Marburg, Germany
Mol Imaging 12:129-36. 2013..Targeted antiangiogenic therapy can induce luciferase activity where transcription is controlled by an hsp70 promoter and HSP70 protein in melanoma tumors...
Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor modelWalter Hundt
Stanford School of Medicine, Lucas MRS Research Center, Department of Radiology, Stanford, California, USA
J Biomed Opt 17:065001. 2012..Thus, targeted antiangiogenic therapy can induce Hsp70 expression and HSP70 protein in melanoma tumors...
In vivo monitoring of antiangiogenic therapy by magnetic resonance and bioluminescence imaging in an M21 tumor model through activation of an hsp70 promoter-luciferase reporter constructWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
Contrast Media Mol Imaging 7:450-9. 2012..Moreover, MRI showed a significant reduction of the contrast medium uptake parameters and an increase in the diffusion coefficient of the tumors...
Novel approach to complex pulmonary arteriovenous malformation embolization using detachable coils and Amplatzer vascular plugsWalter Hundt
Department of Radiology, Philipps University Marburg, Baldingerstrasse 35043, Marburg, Germany
Eur J Radiol 81:e732-8. 2012....
Gene expression analysis of SCC tumor cells in muscle tissueWalter Hundt
Department of Radiology, Philipps University Marburg, Marburg, Germany
Eur Arch Otorhinolaryngol 269:1653-63. 2012..Gene expression analysis revealed changes in the expression levels of SCCVII cells in muscle tissue in 220 genes. Significant gene expression differences between SCCVII cells in muscle tissue and pure muscle tissue could be seen...
Evaluation of contrast medium enhancement and [(18)F]-FDG uptake of liver metastasis in PET/CT prior to therapyWalter Hundt
Department of Radiology, Philipps University Marburg, Baldingerstrasse, D 35043 Marburg, Germany
Eur J Radiol 81:652-7. 2012..To evaluate the contrast medium enhancement and [(18)F]-FDG uptake of liver metastases in patients suffering from colon or breast carcinoma prior to therapy...
Modulation of luciferase activity using high intensity focused ultrasound in combination with bioluminescence imaging, magnetic resonance imaging and histological analysis in muscle tissueWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
Ultrasonics 49:549-57. 2009..9 W/cm2 and 802.0 W/cm2 14.1 +/- 3.6 x 10(6) photon/s (6.1 +/- 1.5-fold), respectively, 5.1 +/- 4.7 x 10(6) photon/s (6.5 +/- 2.0-fold). HIFU can enhance the luciferase activity controlled by a CMV-promoter...
Induction of luciferase activity under the control of an hsp70 promoter using high-intensity focused ultrasound: combination of bioluminescence and MRI imaging in three different tumour modelsW Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
Technol Cancer Res Treat 10:197-210. 2011....
The effect of high intensity focused ultrasound on luciferase activity on two tumor cell lines in vitro, under the control of a CMV promoterWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
Ultrasonics 49:312-8. 2009..Our findings demonstrate that HIFU can enhance the luciferase activity controlled by a CMV promoter. However it also has a higher damaging effect on the cells...
Comparison of continuous vs. pulsed focused ultrasound in treated muscle tissue as evaluated by magnetic resonance imaging, histological analysis, and microarray analysisWalter Hundt
Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305 5488, USA
Eur Radiol 18:993-1004. 2008....
In vitro effect of focused ultrasound or thermal stress on HSP70 expression and cell viability in three tumor cell linesWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA, USA
Acad Radiol 14:859-70. 2007..In this study, we compared the effect of focused ultrasound with the effect of thermal stress on the induction of a heat inducible promoter in an in vitro model using three tumor cell lines (M21, SCCVII, and NIH3T3)...
Tumor tissue characterization evaluating the luciferase activity under the control of a hsp70 promoter and MR imaging in three tumor cell linesWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA 94305, USA
Eur J Radiol 70:369-77. 2009..The combination of MR imaging with bioluminescence imaging improves the characterization of tumor tissue giving better information of this tissue on the molecular level...
Mechanic effect of pulsed focused ultrasound in tumor and muscle tissue evaluated by MRI, histology, and microarray analysisWalter Hundt
Lucas MRS Research Center, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305 5488, USA
Eur J Radiol 76:279-87. 2010..Pulsed HIFU treatment on tumor and muscle tissue results in dramatic changes in gene expression, indicating that the effect of pulsed HIFU is in some regard dependent and also independent of the tissue type...
Gene expression profiles, histologic analysis, and imaging of squamous cell carcinoma model treated with focused ultrasound beamsWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA
AJR Am J Roentgenol 189:726-36. 2007....
Use of in vivo bioluminescence and MRI to determine hyperthermia-induced changes in luciferase activity under the control of an hsp70 promoterWalter Hundt
Department of Radiology, Lucas MRS Research Center, Stanford School of Medicine, Stanford, CA, USA Department of Radiology, Philipps University, Marburg, Germany
NMR Biomed 25:1378-91. 2012..The major finding of the present study was that heat-related biochemical changes in tumor tissue can be determined by MRI. Copyright © 2012 John Wiley & Sons, Ltd...
Low flow vascular malformations of the head and neck: a study on brightness mode, color coded duplex and spectral Doppler sonographyBehfar Eivazi
Division of Angiology, Department of Otolaryngology, Head and Neck Surgery, University of Marburg, Deutschhausstr 3, 35037 Marburg, Germany
Eur Arch Otorhinolaryngol 268:1505-11. 2011..When considering differentiating among LFVM, features such as the echogenecity, spectral Doppler wave forms, and the evidence of phleboliths contribute to establish the correct diagnosis...
Does hereditary hemorrhagic telangiectasia affect olfactory or gustatory function?Silke Steinbach
Department of Otorhinolaryngology, Philipps University, Marburg, Germany
Am J Rhinol Allergy 26:463-8. 2012..Disorders of the nasal/oral cavity may interfere with the olfactory and gustatory functions. Fifty-four HHT patients were investigated by smell/taste tests...
Effect of platinum-containing chemotherapy on olfactory, gustatory, and hearing function in ovarian cancer patientsSilke Steinbach
Department of Otorhinolaryngology, Philipps University, Baldingerstrasse, 35033 Marburg, Germany
Arch Gynecol Obstet 286:473-80. 2012..Therefore, one of the main therapeutic aims after cytoreductive surgery for these patients is to identify, delay and relieve chemotherapy-induced side effects and optimise the quality of life, especially after first-line therapy...
