Markus O Henke

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. doi [Heart and lungs : Cardinal symptom dyspnea]
    M O Henke
    Klinik für Innere Medizin mit Schwerpunkt Pneumologie, Universitätsklinikum Marburg, UKGM Marburg, Baldingerstr 1, 35043, Marburg, Deutschland
    Herz 38:279-90. 2013
  2. ncbi Up-regulation of S100A8 and S100A9 protein in bronchial epithelial cells by lipopolysaccharide
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg, Germany
    Exp Lung Res 32:331-47. 2006
  3. ncbi MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation
    Markus O Henke
    Philipps University Marburg, Department of Pulmonary Medicine, Baldingerstrasse 1, 35043 Marburg, Germany
    Am J Respir Crit Care Med 175:816-21. 2007
  4. pmc Serine proteases degrade airway mucins in cystic fibrosis
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany
    Infect Immun 79:3438-44. 2011
  5. doi Reduced surface toll-like receptor-4 expression and absent interferon-γ-inducible protein-10 induction in cystic fibrosis airway cells
    Gerrit John
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg, Germany
    Exp Lung Res 37:319-26. 2011
  6. doi TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells
    Gerrit John
    Philipps University Marburg, Department of Pulmonary Medicine, Baldingerstrasse 1, 35043 Marburg, Germany
    Am J Respir Cell Mol Biol 42:424-31. 2010
  7. ncbi MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Germany
    Am J Respir Cell Mol Biol 31:86-91. 2004
  8. ncbi The role of airway secretions in COPD--clinical applications
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg 35043, Germany
    COPD 2:377-90. 2005
  9. ncbi Mucolytics in cystic fibrosis
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, 35043 Marburg, Germany
    Paediatr Respir Rev 8:24-9. 2007
  10. ncbi The role of DNA and actin polymers on the polymer structure and rheology of cystic fibrosis sputum and depolymerization by gelsolin or thymosin beta 4
    Arnon Kater
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157 1081, USA
    Ann N Y Acad Sci 1112:140-53. 2007

Collaborators

Detail Information

Publications12

  1. doi [Heart and lungs : Cardinal symptom dyspnea]
    M O Henke
    Klinik für Innere Medizin mit Schwerpunkt Pneumologie, Universitätsklinikum Marburg, UKGM Marburg, Baldingerstr 1, 35043, Marburg, Deutschland
    Herz 38:279-90. 2013
    ....
  2. ncbi Up-regulation of S100A8 and S100A9 protein in bronchial epithelial cells by lipopolysaccharide
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg, Germany
    Exp Lung Res 32:331-47. 2006
    ..This finding suggests that S100A8 and S100A9 are involved in the innate defense of the bronchial epithelium...
  3. ncbi MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation
    Markus O Henke
    Philipps University Marburg, Department of Pulmonary Medicine, Baldingerstrasse 1, 35043 Marburg, Germany
    Am J Respir Crit Care Med 175:816-21. 2007
    ..However, we have shown that these mucins are decreased during stable CF disease...
  4. pmc Serine proteases degrade airway mucins in cystic fibrosis
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany
    Infect Immun 79:3438-44. 2011
    ..aeruginosa, and after that, the mucin concentration decreases dramatically. This is most likely due to degradation by serine proteases. The loss of this mucin barrier may contribute to chronic airway infection in the CF airway...
  5. doi Reduced surface toll-like receptor-4 expression and absent interferon-γ-inducible protein-10 induction in cystic fibrosis airway cells
    Gerrit John
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg, Germany
    Exp Lung Res 37:319-26. 2011
    ..The reduced TLR-4 surface expression in CF cells causes the loss of induction of IP-10 by LPS. This could compromise adaptive immune responses in CF due to a reduced T-cell recruitment...
  6. doi TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells
    Gerrit John
    Philipps University Marburg, Department of Pulmonary Medicine, Baldingerstrasse 1, 35043 Marburg, Germany
    Am J Respir Cell Mol Biol 42:424-31. 2010
    ..In CF the loss of CFTR function appears to decrease innate immune responses, possibly by altering the expression of TLR-4 on airway epithelial cells. This may contribute to chronic bacterial infection of CF airways...
  7. ncbi MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Germany
    Am J Respir Cell Mol Biol 31:86-91. 2004
    ..This may be due to a relative increase in other components of sputum in the CF airway or to a primary defect in mucin secretion in CF...
  8. ncbi The role of airway secretions in COPD--clinical applications
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, Marburg 35043, Germany
    COPD 2:377-90. 2005
    ..Carefully conducted studies of interventions to improve airway clearance, similar to those done in cystic fibrosis (CF), may help us to identify effective therapies and possibly novel diagnostic tests for the management of COPD...
  9. ncbi Mucolytics in cystic fibrosis
    Markus O Henke
    Department of Pulmonary Medicine, Philipps University Marburg, 35043 Marburg, Germany
    Paediatr Respir Rev 8:24-9. 2007
    ..Ultimately, drugs that are mucokinetic, which preserve viscoelasticity, rather than mucolytic may prove to be beneficial for CF lung disease in the future...
  10. ncbi The role of DNA and actin polymers on the polymer structure and rheology of cystic fibrosis sputum and depolymerization by gelsolin or thymosin beta 4
    Arnon Kater
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157 1081, USA
    Ann N Y Acad Sci 1112:140-53. 2007
    ....
  11. ncbi Mucus properties in children with primary ciliary dyskinesia: comparison with cystic fibrosis
    Andrew Bush
    Pediatric Pulmonology, Imperial School of Medicine at National Heart and Lung Institute, London, UK
    Chest 129:118-23. 2006
    ..Our objective was to compare the biophysical and transport properties of CF and PCD sputa in subjects matched for age and degree of lung function impairment...
  12. ncbi Immunomodulatory activity and effectiveness of macrolides in chronic airway disease
    Bruce K Rubin
    Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1081, USA
    Chest 125:70S-78S. 2004
    ..The immunomodulatory effects of the macrolides also may be beneficial for the treatment of other chronic inflammatory conditions...