Antonia Flaquer

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi A new sex-specific genetic map of the human pseudoautosomal regions (PAR1 and PAR2)
    Antonia Flaquer
    Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany
    Hum Hered 68:192-200. 2009
  2. ncbi A new susceptibility locus for bipolar affective disorder in PAR1 on Xp22.3/Yp11.3
    Antonia Flaquer
    Institute of Medical Biometry and Epidemiology, Philipps University Marburg, Marburg, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:1110-4. 2010
  3. ncbi Susceptibility variants for male-pattern baldness on chromosome 20p11
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, D 53127 Bonn, Germany
    Nat Genet 40:1279-81. 2008
  4. ncbi Genome-wide scan and fine-mapping linkage study of androgenetic alopecia reveals a locus on chromosome 3q26
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, D 53127 Bonn, Germany
    Am J Hum Genet 82:737-43. 2008
  5. ncbi Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24
    Johannes Schumacher
    Institute of Human Genetics, Life and Brain Center, University of Bonn, D-53105 Bonn, Germany
    Am J Hum Genet 77:1102-11. 2005
  6. ncbi The human pseudoautosomal regions: a review for genetic epidemiologists
    Antonia Flaquer
    Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, Bonn, Germany
    Eur J Hum Genet 16:771-9. 2008
  7. ncbi Linkage analysis of alcohol dependence using MOD scores
    Konstantin Strauch
    Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    BMC Genet 6:S162. 2005
  8. ncbi Evaluation of potential power gain with imputed genotypes in genome-wide association studies
    Tim Becker
    Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany
    Hum Hered 68:23-34. 2009
  9. ncbi Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany
    Am J Hum Genet 77:140-8. 2005
  10. ncbi Loss-of-function mutations in the filaggrin gene and alopecia areata: strong risk factor for a severe course of disease in patients comorbid for atopic disease
    Regina C Betz
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    J Invest Dermatol 127:2539-43. 2007

Detail Information

Publications10

  1. ncbi A new sex-specific genetic map of the human pseudoautosomal regions (PAR1 and PAR2)
    Antonia Flaquer
    Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany
    Hum Hered 68:192-200. 2009
    ..Accurate sex-specific genetic maps are essential for gene mapping projects when using multipoint methods, especially for the pseudoautosomal regions (PARs). This paper describes a new sex-specific genetic map for the human PARs...
  2. ncbi A new susceptibility locus for bipolar affective disorder in PAR1 on Xp22.3/Yp11.3
    Antonia Flaquer
    Institute of Medical Biometry and Epidemiology, Philipps University Marburg, Marburg, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:1110-4. 2010
    ..This region has not drawn much attention in previous linkage studies of BPAD. On the basis of these results, Xp22.3/Yp11.3 should now be considered a candidate region for BPAD...
  3. ncbi Susceptibility variants for male-pattern baldness on chromosome 20p11
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, D 53127 Bonn, Germany
    Nat Genet 40:1279-81. 2008
    ..7 x 10(-15)). No interaction was detected with the X-chromosomal androgen receptor locus, suggesting that the 20p11 locus has a role in a yet-to-be-identified androgen-independent pathway...
  4. ncbi Genome-wide scan and fine-mapping linkage study of androgenetic alopecia reveals a locus on chromosome 3q26
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, D 53127 Bonn, Germany
    Am J Hum Genet 82:737-43. 2008
    ..97 (empirical p value = 0.00055). This is the first step toward the identification of new susceptibility genes in AGA, a process which will provide important insights into the molecular and cellular basis of scalp hair loss...
  5. ncbi Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24
    Johannes Schumacher
    Institute of Human Genetics, Life and Brain Center, University of Bonn, D-53105 Bonn, Germany
    Am J Hum Genet 77:1102-11. 2005
    ....
  6. ncbi The human pseudoautosomal regions: a review for genetic epidemiologists
    Antonia Flaquer
    Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, Bonn, Germany
    Eur J Hum Genet 16:771-9. 2008
    ..This drawback could be solved with a sufficient number of markers, statistical methods that are adopted for the PARs, and their integration into softwares...
  7. ncbi Linkage analysis of alcohol dependence using MOD scores
    Konstantin Strauch
    Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    BMC Genet 6:S162. 2005
    ..A tendency to maternal imprinting was observed at two loci on chromosome 7. Our findings underscore the fact that an adequate modeling of the genotype-phenotype relation is crucial for the genetic mapping of a complex trait...
  8. ncbi Evaluation of potential power gain with imputed genotypes in genome-wide association studies
    Tim Becker
    Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany
    Hum Hered 68:23-34. 2009
    ..In this context, an evaluation of genome-wide power levels of current marker panels and the power gain achievable with imputed genotypes are of high interest...
  9. ncbi Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia
    Axel M Hillmer
    Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany
    Am J Hum Genet 77:140-8. 2005
    ..The X-chromosomal location of AR stresses the importance of the maternal line in the inheritance of AGA...
  10. ncbi Loss-of-function mutations in the filaggrin gene and alopecia areata: strong risk factor for a severe course of disease in patients comorbid for atopic disease
    Regina C Betz
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    J Invest Dermatol 127:2539-43. 2007
    ..003; odds ratio (OR)=5.47 (95% confidence interval (CI): 1.59-18.76)). In conclusion, our data suggest that when AA occurs in conjunction with FLG-associated atopic disorder, the clinical presentation of AA may be more severe...