Robert Finking

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Biosynthesis of nonribosomal peptides1
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    Annu Rev Microbiol 58:453-88. 2004
  2. ncbi request reprint Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall
    Juergen J May
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Marburg, Germany
    FEBS J 272:2993-3003. 2005
  3. ncbi request reprint Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, D 35032 Marburg, Germany
    Biochemistry 43:8946-56. 2004
  4. ncbi request reprint Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism
    Mohammad Reza Mofid
    Fachbereich Chemie Biochemie, Philipps Universitat Marburg, Hans Meerwein Strasse, D 35032 Marburg, Germany
    Biochemistry 43:4128-36. 2004
  5. ncbi request reprint Aminoacyl adenylate substrate analogues for the inhibition of adenylation domains of nonribosomal peptide synthetases
    Robert Finking
    Fachbereich Chemie Biochemie, Philipps Universitat Marburg, Hans Meerwein Strasse, 35032 Marburg, Germany
    Chembiochem 4:903-6. 2003
  6. ncbi request reprint Characterization of a new type of phosphopantetheinyl transferase for fatty acid and siderophore synthesis in Pseudomonas aeruginosa
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    J Biol Chem 277:50293-302. 2002
  7. ncbi request reprint Recognition of hybrid peptidyl carrier proteins/acyl carrier proteins in nonribosomal peptide synthetase modules by the 4'-phosphopantetheinyl transferases AcpS and Sfp
    Mohammad Reza Mofid
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, D 35032 Marburg, Germany
    J Biol Chem 277:17023-31. 2002
  8. ncbi request reprint Nonribosomal peptides: from genes to products
    Dirk Schwarzer
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    Nat Prod Rep 20:275-87. 2003

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Biosynthesis of nonribosomal peptides1
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    Annu Rev Microbiol 58:453-88. 2004
    ....
  2. ncbi request reprint Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall
    Juergen J May
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Marburg, Germany
    FEBS J 272:2993-3003. 2005
    ..We also performed in vivo studies and determined a significant inhibition of growth for different Bacillus subtilis strains when the inhibitor is used in combination with vancomycin...
  3. ncbi request reprint Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, D 35032 Marburg, Germany
    Biochemistry 43:8946-56. 2004
    ..These altered PCPs were still capable of serving their designated function in NRPS modules, and selective use of AcpS or Sfp leads to production of two different products by a trimodular NRPS...
  4. ncbi request reprint Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism
    Mohammad Reza Mofid
    Fachbereich Chemie Biochemie, Philipps Universitat Marburg, Hans Meerwein Strasse, D 35032 Marburg, Germany
    Biochemistry 43:4128-36. 2004
    ..Also, residues T44, K75, S89, H90, D107, E109, E151, and K155 that have been shown in the Sfp-CoA cocrystal structure to coordinate CoA are now all confirmed by mutational and biochemical analysis...
  5. ncbi request reprint Aminoacyl adenylate substrate analogues for the inhibition of adenylation domains of nonribosomal peptide synthetases
    Robert Finking
    Fachbereich Chemie Biochemie, Philipps Universitat Marburg, Hans Meerwein Strasse, 35032 Marburg, Germany
    Chembiochem 4:903-6. 2003
  6. ncbi request reprint Characterization of a new type of phosphopantetheinyl transferase for fatty acid and siderophore synthesis in Pseudomonas aeruginosa
    Robert Finking
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    J Biol Chem 277:50293-302. 2002
    ..This association with enzymes of primary and secondary metabolism indicates that PcpS belongs to a new sub-class of PPTases...
  7. ncbi request reprint Recognition of hybrid peptidyl carrier proteins/acyl carrier proteins in nonribosomal peptide synthetase modules by the 4'-phosphopantetheinyl transferases AcpS and Sfp
    Mohammad Reza Mofid
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, D 35032 Marburg, Germany
    J Biol Chem 277:17023-31. 2002
    ..Nevertheless, hTycA is recognized by the next proline-activating elongation module TycB1 in vitro, and the dipeptide is formed and released as diketopiperazine...
  8. ncbi request reprint Nonribosomal peptides: from genes to products
    Dirk Schwarzer
    Philipps Universitat Marburg, Fachbereich Chemie Biochemie, Hans Meerwein Strasse, 35043 Marburg, Germany
    Nat Prod Rep 20:275-87. 2003
    ..In addition, possibilities and limitations for prediction of structural features of uncharacterized NRPSs and approaches for their engineering are discussed...