Richard Dodel

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Health-related quality of life in patients with narcolepsy
    Richard Dodel
    Department of Neurology, Philipps University, Marburg, Germany
    Sleep Med 8:733-41. 2007
  2. doi request reprint [Multimorbidity: concept, epidemiology and treatment]
    R Dodel
    Klinik und Poliklinik fur Neurologie, Philipps Universitat Marburg, Universitätsklinikum Gießen und Marburg, Baldingerstr 1, 35043, Marburg, Deutschland
    Nervenarzt 85:401-8. 2014
  3. pmc Preference-based Health status in a German outpatient cohort with multiple sclerosis
    Jens Peter Reese
    Department of Neurology, Philipps University, Marburg, Germany
    Health Qual Life Outcomes 11:162. 2013
  4. pmc Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia
    Maike Gold
    Department of Neurology, Philipps University of Marburg, Baldingerstraße 1, 35043, Marburg, Germany
    J Neuroinflammation 10:5. 2013
  5. doi request reprint Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
    Richard Dodel
    University Hospital Giessen and Marburg, Philipps University Marburg, Marburg, Germany
    Lancet Neurol 12:233-43. 2013
  6. ncbi request reprint [The costs of epilepsy in Germany]
    Richard Dodel
    Neurologische Klinik, Philipps Universitat Marburg, Rudolf Bultmannstr 8, 35039 Marburg
    Pharm Unserer Zeit 36:298-305. 2007
  7. doi request reprint Lewy body dementia and Parkinson's disease with dementia
    Richard Dodel
    Dept of Neurology, Philipps University Marburg, Marburg, Germany
    J Neurol 255:39-47. 2008
  8. doi request reprint [Innovative treatment approaches for Alzheimer's disease. Immunotherapy]
    R Dodel
    Arbeitsgruppe Neurologische Therapieforschung, Neurologische Klinik, Philipps Universitat Marburg, Rudolf Bultmann Strasse 8, 35039, Marburg
    Nervenarzt 79:149-57; quiz 158. 2008
  9. doi request reprint Cost of illness in subarachnoid hemorrhage: a German longitudinal study
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Stroke 41:2918-23. 2010
  10. doi request reprint Intravenous immunoglobulins as a treatment for Alzheimer's disease: rationale and current evidence
    Richard Dodel
    Department of Neurology, Philipps University, Marburg, Germany
    Drugs 70:513-28. 2010

Detail Information

Publications85

  1. ncbi request reprint Health-related quality of life in patients with narcolepsy
    Richard Dodel
    Department of Neurology, Philipps University, Marburg, Germany
    Sleep Med 8:733-41. 2007
    ..To evaluate the health-related quality of life (HRQoL) in patients suffering from narcolepsy...
  2. doi request reprint [Multimorbidity: concept, epidemiology and treatment]
    R Dodel
    Klinik und Poliklinik fur Neurologie, Philipps Universitat Marburg, Universitätsklinikum Gießen und Marburg, Baldingerstr 1, 35043, Marburg, Deutschland
    Nervenarzt 85:401-8. 2014
    ..The aim of this article is to give a brief overview on the concept of multimorbidity and comorbidity, to present epidemiological data and to describe the care of patients with multiple illnesses in the German context. ..
  3. pmc Preference-based Health status in a German outpatient cohort with multiple sclerosis
    Jens Peter Reese
    Department of Neurology, Philipps University, Marburg, Germany
    Health Qual Life Outcomes 11:162. 2013
    ..To prospectively determine health status and health utility and its predictors in patients with multiple sclerosis (MS)...
  4. pmc Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia
    Maike Gold
    Department of Neurology, Philipps University of Marburg, Baldingerstraße 1, 35043, Marburg, Germany
    J Neuroinflammation 10:5. 2013
    ....
  5. doi request reprint Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
    Richard Dodel
    University Hospital Giessen and Marburg, Philipps University Marburg, Marburg, Germany
    Lancet Neurol 12:233-43. 2013
    ..We tested the safety, effective dose, and infusion interval of intravenous immunoglobulin in such patients...
  6. ncbi request reprint [The costs of epilepsy in Germany]
    Richard Dodel
    Neurologische Klinik, Philipps Universitat Marburg, Rudolf Bultmannstr 8, 35039 Marburg
    Pharm Unserer Zeit 36:298-305. 2007
  7. doi request reprint Lewy body dementia and Parkinson's disease with dementia
    Richard Dodel
    Dept of Neurology, Philipps University Marburg, Marburg, Germany
    J Neurol 255:39-47. 2008
    ..This article focuses on the clinical issues related to both disorders and is based on a meeting of experts which took place in April 2008 in Dresden...
  8. doi request reprint [Innovative treatment approaches for Alzheimer's disease. Immunotherapy]
    R Dodel
    Arbeitsgruppe Neurologische Therapieforschung, Neurologische Klinik, Philipps Universitat Marburg, Rudolf Bultmann Strasse 8, 35039, Marburg
    Nervenarzt 79:149-57; quiz 158. 2008
    ..In this review we present the current status of the different approaches in relation to Alzheimer's disease as well as to other neurodegenerative disorders...
  9. doi request reprint Cost of illness in subarachnoid hemorrhage: a German longitudinal study
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Stroke 41:2918-23. 2010
    ..The objective was to evaluate first-year costs in German patients with aneurysmal SAH and to identify independent determinants of costs...
  10. doi request reprint Intravenous immunoglobulins as a treatment for Alzheimer's disease: rationale and current evidence
    Richard Dodel
    Department of Neurology, Philipps University, Marburg, Germany
    Drugs 70:513-28. 2010
    ..In this article, we review the current knowledge and scientific rationale for using IVIG in patients with AD and other neurodegenerative disorders...
  11. doi request reprint Health economic burden of patients with restless legs syndrome in a German ambulatory setting
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Pharmacoeconomics 28:381-93. 2010
    ..RLS places a notable financial burden on society as well as on patients and their families. More detailed studies are needed to evaluate the health economic impact of this disorder...
  12. doi request reprint Naturally occurring autoantibodies against beta-amyloid: investigating their role in transgenic animal and in vitro models of Alzheimer's disease
    Richard Dodel
    Department of Neurology, Philipps University Marburg, D 35043 Marburg, Germany
    J Neurosci 31:5847-54. 2011
    ..These findings suggest a novel physiological mechanism involving NAbs-Aβ to dispose of proteins or peptides that are prone to forming toxic aggregates...
  13. doi request reprint Trends in resource utilization for Parkinson's disease in Germany
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Str 8, 35039 Marburg, Germany
    J Neurol Sci 294:18-22. 2010
    ..The prevalence of Parkinson's disease (PD) and costs of healthcare resources for this disease have been increasing in recent years. The objective was to determine the trends in the resource utilization for PD in Germany...
  14. pmc The role of macrophage migration inhibitory factor in Alzheimer's disease
    Michael Bacher
    Department of Neurology, Philipps University Marburg, Germany
    Mol Med 16:116-21. 2010
    ....
  15. doi request reprint Social and clinical determinants of quality of life in Parkinson's disease in Austria: a cohort study
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Rudolf Bultmannstr 8, 35039, Marburg, Germany
    J Neurol 257:638-45. 2010
    ..The analysis of determinants of HrQoL showed that a greater attention should be paid to social support and home care. Our data on HrQoL in PD should be considered in the development of new health care programs...
  16. doi request reprint Impact of complications and comorbidities on treatment costs and health-related quality of life of patients with Parkinson's disease
    Jan Philipp Bach
    Philipps University Marburg, Department of Neurology, Germany
    J Neurol Sci 314:41-7. 2012
    ..Likewise, the reported impact of drug costs on total direct costs varies across different studies. In addition, the influence of comorbidities on both treatment costs and health-related quality of life has not been adequately evaluated...
  17. doi request reprint Health-related quality of life in multiple system atrophy and progressive supranuclear palsy
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Neurodegener Dis 8:438-46. 2011
    ..The objective of our cross-sectional study was to evaluate the HrQoL in patients with APS and to identify the determinants of HrQoL...
  18. doi request reprint Costs of Parkinson's disease and antiparkinsonian pharmacotherapy: an Italian cohort study
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Neurodegener Dis 7:365-72. 2010
    ..The objective of this study was to investigate the costs of PD and antiparkinsonian drugs in an Italian cohort of patients and identify cost-driving factors of drug therapy...
  19. ncbi request reprint Direct and indirect costs of refractory epilepsy in a tertiary epilepsy center in Germany
    Hajo M Hamer
    Department of Neurology, Philipps University, Marburg, Germany
    Epilepsia 47:2165-72. 2006
    ..There are only few studies on the costs of epilepsy in Germany. Therefore, we performed a pilot study to estimate the direct and indirect costs of refractory epilepsy in a German epilepsy center...
  20. doi request reprint Trends in resource utilization and prescription of anticonvulsants for patients with active epilepsy in Germany
    Adam Strzelczyk
    Department of Neurology and Epilepsy Center Hessen, Philipps University, Marburg, Germany
    Epilepsy Behav 27:433-8. 2013
    ..The amount and distribution of indirect cost components remained unchanged...
  21. doi request reprint Health-related quality of life in ALS, myasthenia gravis and facioscapulohumeral muscular dystrophy
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Rudolf Bultmannstr 8, Marburg, Germany
    J Neurol 257:1473-81. 2010
    ..In addition to the treatment of motor symptoms, greater attention should be paid to the treatment of depression, which was found to be among the independent predictors of the HRQoL in ALS and MG...
  22. doi request reprint Role of macrophage migration inhibitory factor in primary glioblastoma multiforme cells
    Nina Baron
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    J Neurosci Res 89:711-7. 2011
    ..These results underscore the importance of MIF in GBM and show that MIF and its receptors may be a promising target for the treatment of malignant gliomas...
  23. doi request reprint Social and clinical determinants of quality of life in Parkinson's disease in a Russian cohort study
    Yaroslav Winter
    Dept of Neurology, Philipps University Marburg, Rudolf Bultmannstr 8, 35039 Marburg, Germany
    Parkinsonism Relat Disord 16:243-8. 2010
    ..Our data should be considered in the development of national healthcare programs that seek to provide better social services support for patients with PD...
  24. ncbi request reprint The socioeconomic impact of narcolepsy
    Richard Dodel
    Department of Neurology, Friedrich Wilhelms University Bonn, Germany
    Sleep 27:1123-8. 2004
    ..To evaluate the economic burden of patients suffering from narcolepsy...
  25. doi request reprint Costs of Parkinson's disease in eastern Europe: a Czech cohort study
    Yaroslav Winter
    Dept of Neurology, Philipps University, Marburg, Germany
    Parkinsonism Relat Disord 16:51-6. 2010
    ..More intensive government support for patients with chronic diseases such as PD and the development of disease-management programs that incorporate both the clinical and economic effects of PD treatment are needed...
  26. doi request reprint Costs of illness and care in Parkinson's disease: an evaluation in six countries
    Sonja von Campenhausen
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Strasse 8, Marburg, Germany
    Eur Neuropsychopharmacol 21:180-91. 2011
    ..However, inpatient care, long-term care and medication were identified as the major expenditures in the investigated countries...
  27. doi request reprint Evaluation of health-care utilization among adult patients with epilepsy in Germany
    Adam Strzelczyk
    Department of Neurology and Epilepsy Center Hessen, Philipps University, Marburg, Germany
    Epilepsy Behav 23:451-7. 2012
    ..9%) and days off due to seizures (26.2%). The mean costs of epilepsy found in our study were lower than those found in studies conducted at European epilepsy centers due to the inclusion of patients in all health-care sectors...
  28. doi request reprint Peripheral and central biodistribution of (111)In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease
    Michael Bacher
    Department of Neurology, Philipps University, Rudolf Bultmann Str 8, 35033 Marburg, Germany
    Neurosci Lett 449:240-5. 2009
    ..Further studies with human immunoglobulins and particularly with those that recognize different Abeta-epitopes are required in order to delineate in more detail the mode of action of NAbs-Abeta...
  29. doi request reprint Health-related quality of life and its determinants in Parkinson's disease: results of an Italian cohort study
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Rudolf Bultmannstrasse 8, Marburg, Germany
    Parkinsonism Relat Disord 17:265-9. 2011
    ..In particular, these programmes should concentrate not only on motor but also on non-motor manifestations of PD...
  30. doi request reprint APP transgenic mice: the effect of active and passive immunotherapy in cognitive tasks
    Stephan Röskam
    Department of Neurology, Research Group for Neurological Therapeutics, Biomedical Research Centre, Philipps University Marburg, Hans Meerwein Strasse, 35043 Marburg, Germany
    Neurosci Biobehav Rev 34:487-99. 2010
    ..This review focuses on such cognitive outcomes of different active and passive immunization strategies in APP transgenic mice...
  31. pmc Mapping the EQ-5D index by UPDRS and PDQ-8 in patients with Parkinson's disease
    Judith Dams
    Department of Neurology, Philipps University, Marburg, Germany
    Health Qual Life Outcomes 11:35. 2013
    ..We aimed to develop an estimation algorithm for EuroQol- 5 dimensions (EQ-5D)-based utilities from the clinical UPDRS or disease-specific HrQoL data in the absence of original utilities estimates...
  32. doi request reprint Affective and cognitive Theory of Mind in patients with parkinson's disease
    Maren E Bodden
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Parkinsonism Relat Disord 16:466-70. 2010
    ....
  33. doi request reprint Prevalence, utilization, and costs of antiepileptic drugs for epilepsy in Germany--a nationwide population-based study in children and adults
    Hajo M Hamer
    Department of Neurology, Epilepsy Center, University of Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany
    J Neurol 259:2376-84. 2012
    ..1/1,000. Family physicians cared for the majority of patients. Prevalence and prescribing patterns changed with age. Costs of AED against epilepsy added up to 1 % of total medication costs in Germany...
  34. doi request reprint The role of CNI-1493 in the function of primary microglia with respect to amyloid-β
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    J Alzheimers Dis 26:69-80. 2011
    ..Therefore, CNI-1493 is a promising candidate for the treatment of AD...
  35. doi request reprint Naturally occurring α-synuclein autoantibody levels are lower in patients with Parkinson disease
    Daniela Besong-Agbo
    Department of Neurology, Philipps University Marburg, Marburg
    Neurology 80:169-75. 2013
    ..Recently, naturally occurring autoantibodies against α-Syn (α-Syn-nAbs) have been detected in the serum of patients with PD. They represent a putative diagnostic marker for PD...
  36. doi request reprint Cost-of-illness in multiple system atrophy and progressive supranuclear palsy
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Baldingerstrasse, 35043, Marburg, Germany
    J Neurol 258:1827-34. 2011
    ..The early diagnosis and treatment of depression in patients with atypical parkinsonian syndromes as well as programs aimed to improve social support will reduce disease-related costs...
  37. doi request reprint Cost-effectiveness of deep brain stimulation in patients with Parkinson's disease
    Judith Dams
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Mov Disord 28:763-71. 2013
    ..Our data support adopting and reimbursing deep brain stimulation within the German health care system...
  38. doi request reprint Costs of illness in a Russian cohort of patients with Parkinson's disease
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Pharmacoeconomics 27:571-84. 2009
    ..While cost-of-illness studies for PD from developed countries have recently been published, data for Eastern Europe and Asia are still lacking...
  39. doi request reprint Parkinson's disease and dementia: a longitudinal study (DEMPARK)
    Monika Balzer-Geldsetzer
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Neuroepidemiology 37:168-76. 2011
    ..Parkinson's disease (PD) is a progressive neurodegenerative motor disorder. However, non-motor complications frequently alter the course of the disease. A particularly disabling non-motor symptom is dementia...
  40. doi request reprint [Cost of illness and health service patterns in Morbus Parkinson in Austria]
    Sonja von Campenhausen
    Neurologische Klinik, Philipps Universitat Marburg, Germany
    Wien Klin Wochenschr 121:574-82. 2009
    ..Continuously increasing healthcare costs and the fact that the prevalence of PD is expected to double in the next 25 years highlight the importance of health-economic evaluation in PD...
  41. doi request reprint Cost of illness in patients with Gilles de la Tourette's syndrome
    Ines Dodel
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Str 8, Marburg, Germany
    J Neurol 257:1055-61. 2010
    ..Unfortunately, no cost of illness studies are available for comparison. Further health economic studies, especially cost-effectiveness studies, are necessary for a basis for rational resource allocation...
  42. doi request reprint Immunotherapy and naturally occurring autoantibodies in neurodegenerative disorders
    Frauke Neff
    Department of Neurology, Philipps University Marburg, Germany
    Autoimmun Rev 7:501-7. 2008
    ..In this review the current knowledge on the role of naturally occurring autoantibodies is discussed in respect to neurodegenerative disorders...
  43. doi request reprint Economic burden in a German cohort of patients with multiple sclerosis
    Jens Peter Reese
    Department of Neurology, Neurological Therapy Research Group, Philipps University Marburg, Marburg, Germany
    Eur Neurol 66:311-21. 2011
    ..To estimate costs of multiple sclerosis (MS) in a German cohort according to severity of the disease and clinical symptoms...
  44. doi request reprint Socioeconomic burden of amyotrophic lateral sclerosis, myasthenia gravis and facioscapulohumeral muscular dystrophy
    Karsten Schepelmann
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    J Neurol 257:15-23. 2010
    ..The socioeconomic burden of NMDs in Germany is considerable. Further studies evaluating both the health-economic and clinical effects of NMD treatment as well as disease management programs and benchmarking activities are necessary...
  45. doi request reprint Cost and care of patients with Alzheimer's disease: clinical predictors in German health care settings
    Jens Peter Reese
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    J Alzheimers Dis 27:723-36. 2011
    ..Direct medical care costs and long-term care costs related differently to the patient's clinical characteristics. Longitudinal and population-based studies are necessary for thoroughly evaluating the burden of disease...
  46. doi request reprint The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Cancer 115:2031-40. 2009
    ..The aim of this article was thus to present a detailed review of current knowledge regarding the role of MIF in CNS tumor pathophysiology...
  47. doi request reprint Pharmacoeconomic considerations of treating patients with advanced Parkinson's disease
    Jens P Reese
    Philipps University Marburg, Department of Neurology, Baldingerstrasse, 35043 Marburg, Germany
    Expert Opin Pharmacother 13:939-58. 2012
    ..Hence, the economic burden of advanced PD is substantial for both the society and the patients with their caregivers...
  48. pmc Restoration of contact inhibition in human glioblastoma cell lines after MIF knockdown
    Jorg Schrader
    Department of Neurology, University of Marburg, Marburg, Germany
    BMC Cancer 9:464. 2009
    ..Studies of the role of the cytokine macrophage-migration-inhibitory-factor (MIF) in malignant tumors have revealed its stimulating influence on cell-cycle progression, angiogenesis and anti-apoptosis...
  49. ncbi request reprint Cost of illness and its predictors for Parkinson's disease in Germany
    Annika E Spottke
    Department of Neurology, Friedrich Wilhelms University, Bonn, Germany
    Pharmacoeconomics 23:817-36. 2005
    ..To prospectively evaluate the health economic burden of patients with Parkinson's disease (PD) in Germany over a 6-month observation period and to identify the predictors of these costs...
  50. doi request reprint Comparison of intravenous immunoglobulins for naturally occurring autoantibodies against amyloid-beta
    Karthikeyan Balakrishnan
    Department of Neurology, Philipps University, Marburg, Germany
    J Alzheimers Dis 20:135-43. 2010
    ..This information, however, may serve as a guide when choosing the commercial source of IVIG for therapeutic applications in Alzheimer's disease...
  51. doi request reprint Evaluation of costs and outcome in cardioembolic stroke or TIA
    Yaroslav Winter
    Department of Neurology, Philipps University, Marburg, Germany
    J Neurol 256:954-63. 2009
    ..Costs of acute care of cardioembolic stroke/TIA patients may exceed those of non-cardioembolic stroke/TIA by up to 40%...
  52. doi request reprint Modelling the cost effectiveness of treatments for Parkinson's disease: a methodological review
    Judith Dams
    Department of Neurology, Philipps University, Marburg, Germany
    Pharmacoeconomics 29:1025-49. 2011
    ..Adverse events of treatment, co-morbidities or disease complications are not yet sufficiently included in the models to adequately represent clinical reality...
  53. ncbi request reprint Health-related quality of life and its determinants in the urban Russian population with major depressive disorder: a cross-sectional study
    Yaroslav Winter
    Dept of Neurology, Philipps University Marburg, Germany
    Int J Psychiatry Med 43:35-49. 2012
    ..The objective of the current study was to evaluate health-related quality of life (HrQoL) and its determinants in outpatients with major depressive disorder in an urban Russian population...
  54. doi request reprint Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial)
    Richard Dodel
    Department of Neurology, Philipps University of Marburg, 35039 Marburg, Germany
    Mov Disord 25:97-107. 2010
    ..This prospective, 48 week, randomized, double-blind, multinational study failed to show a clinical effect of minocycline on symptom severity as assessed by clinical motor function...
  55. doi request reprint Frequency and treatment of depressive symptoms in a Parkinson's disease registry
    Astrid Althaus
    Department of Neurology, Philipps University of Marburg, Germany
    Parkinsonism Relat Disord 14:626-32. 2008
    ..Large scale randomized controlled trials examining efficacy and safety of antidepressants in PD patients are urgently required...
  56. doi request reprint Reducing sample complexity of polyclonal human autoantibodies by chromatofocusing
    Sascha Hagemann
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Str 8, 35037 Marburg, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 878:2249-54. 2010
    ..g. polyclonal IgG preparations, in order to minimize the amount of different proteins in separated fractions in a reproducible way...
  57. doi request reprint Incidence of Parkinson's disease and atypical parkinsonism: Russian population-based study
    Yaroslav Winter
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 25:349-56. 2010
    ..The clinical implication of our study is that it highlights the need for better diagnosis and treatment of depression in early stages of PD...
  58. doi request reprint Centenary of Lewy bodies (1912-2012)
    Bernd Holdorff
    Department of Neurology, Schlossparkklinik Berlin, Grolmanstr 56, 10623, Berlin, Germany
    J Neural Transm 120:509-16. 2013
    ..At the time of Lewy's death in 1950, the era of the Lewy bodies, Lewy-body-disease and the identification of atypical Parkinson syndrome cases had not even begun and followed much later...
  59. doi request reprint Immunotherapy in prion disease
    Yvonne Roettger
    Department of Neurology, Philipps University Marburg, Baldingerstrasse, 35043 Marburg, Germany
    Nat Rev Neurol 9:98-105. 2013
    ..The therapeutic potential of these strategies in treating patients with prion diseases is also discussed...
  60. ncbi request reprint Long-term outcome after stroke: evaluating health-related quality of life using utility measurements
    Caroline Haacke
    Department of Neurology, Philipps University Marburg, Germany
    Stroke 37:193-8. 2006
    ..The purpose of this study was to examine the long-term outcome (4 years after stroke) of HRQoL and to identify the determinants of HRQoL in stroke survivors...
  61. ncbi request reprint Prevalence and incidence of Parkinson's disease in Europe
    Sonja von Campenhausen
    Department of Neurology, Friedrich Wilhelms University, Sigmund Freud Strasse 25, 53127 Bonn, Germany
    Eur Neuropsychopharmacol 15:473-90. 2005
    ..To provide an overview on the prevalence and incidence of Parkinson's disease (PD) in selected European countries...
  62. doi request reprint Pathogenic and physiological autoantibodies in the central nervous system
    Maike Gold
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Immunol Rev 248:68-86. 2012
    ..The numerous actions of physiological autoantibodies as well as their regulation and origin are summarized in this review...
  63. ncbi request reprint The flavanoide caffeic acid phenethyl ester blocks 6-hydroxydopamine-induced neurotoxicity
    Carmen Noelker
    Department of Neurology, Friedrich Wilhelms University, Bonn, Germany
    Neurosci Lett 383:39-43. 2005
    ....
  64. ncbi request reprint Cost of epilepsy: a systematic review
    Adam Strzelczyk
    Department of Neurology, Philipps University, Marburg, Germany
    Pharmacoeconomics 26:463-76. 2008
    ..Therefore, there is an urgent need for studies that evaluate direct and indirect costs in a standardized fashion...
  65. doi request reprint Copper deficiency associated with severe neurological disorder--a genetic work-up of possible mutations in copper transport proteins
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Strasse 8, 35039 Marburg, Germany
    J Neurol Sci 291:95-7. 2010
    ..Copper deficiency has been described as resulting in severe neurological impairment. However, mechanisms underlying a copper deficiency are presently unknown...
  66. doi request reprint Health-related quality of life in patients with a history of myocardial infarction and stroke
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Strasse 8, Marburg, Germany
    Cerebrovasc Dis 31:68-76. 2011
    ..There is a lack of the generic data comparing the influence of different diseases on health-related quality of life (HrQoL) in a representative sample of primary care patients...
  67. doi request reprint Blood-based protein biomarkers for diagnosis and classification of neurodegenerative diseases: current progress and clinical potential
    Carmen Noelker
    Department of Neurology, Philipps University Marburg, Germany
    Mol Diagn Ther 15:83-102. 2011
    ..This article provides an overview of this field of research and focuses on recent advances in biomarker research in Alzheimer's disease and Parkinson's disease...
  68. ncbi request reprint Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument
    Elke Kalbe
    Department of Neurology, University Hospital, University of Cologne, Germany
    Parkinsonism Relat Disord 14:93-101. 2008
    ..The mood questionnaire also had high sensitivity and specificity. We conclude that the PANDA is an economical, easy-to-use and sensitive tool to detect neuropsychological dysfunctions in PD patients in clinical practice...
  69. doi request reprint Awareness and knowledge of the clinical practice guideline on Parkinson's disease among German neurologists
    Karla Eggert
    Department of Neurology, Philipps Universitat Marburg, Marburg, Germany
    Eur Neurol 61:216-22. 2009
    ..This study evaluates the awareness and the knowledge of the German practice guideline for Parkinson's disease among neurologists...
  70. doi request reprint Safety and efficacy of perampanel in advanced Parkinson's disease: a randomized, placebo-controlled study
    Karla Eggert
    German Competence Network on Parkinson s Disease, Department of Neurology, Philipps University Marburg, Marburg, Germany
    Mov Disord 25:896-905. 2010
    ..Adverse events were similar across treatment groups. Perampanel treatment was well tolerated and safe, but failed to achieve statistical significance in primary and secondary endpoints...
  71. doi request reprint Antibody-based therapy in Alzheimer's disease
    Refik Pul
    Hannover Medical School, Department of Neurology, Carl Neuberg Str 1, 30625 Hannover, Germany
    Expert Opin Biol Ther 11:343-57. 2011
    ..New upcoming experimental approaches like antibodies recognizing specific conformational epitopes, single-chain variable fragment antibodies, or intrabodies give hope of further drug development for this incurable disease...
  72. doi request reprint Naturally occurring autoantibodies against β-Amyloid
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Germany
    Adv Exp Med Biol 750:91-9. 2012
    ..The results will show whether the application of NAbs will change the fate of the disease. This chapter summarizes our current knowledge on NAbs against Aβ...
  73. ncbi request reprint Costs of acute stroke care on regular neurological wards: a comparison with stroke unit setting
    Yaroslav Epifanov
    Department of Neurology, Klinikum Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, 68167 Mannheim, Germany
    Health Policy 81:339-49. 2007
    ..Since the resource utilization on regular neurological wards is widely unknown, we determined the costs for acute stroke care on regular neurological wards to compare both treatment settings...
  74. doi request reprint Macrophage migration inhibitory factor in normal human skeletal muscle and inflammatory myopathies
    Jens Reimann
    Department of Neurology, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    J Neuropathol Exp Neurol 69:654-62. 2010
    ..These data suggest that MIF is a skeletal muscle cytokine with probable functions beyond inflammatory pathology in the complex regenerative response to muscle fiber damage...
  75. ncbi request reprint Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Germany
    Ann Neurol 52:253-6. 2002
    ..This study provides evidence that intravenous immunoglobulin or purified Abeta antibodies may modify Abeta and Abeta(1-42) levels, suggesting potential utility as a therapy for Alzheimer disease...
  76. doi request reprint Projected numbers of people with movement disorders in the years 2030 and 2050
    Jan Philipp Bach
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Mov Disord 26:2286-90. 2011
    ..Because these disorders pose a major challenge to patients, families, and health care systems, there is a need for reliable data about the future number of affected people...
  77. pmc CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease
    Michael Bacher
    Department of Neurology, Philipps University Marburg, 35039 Marburg, Germany
    J Exp Med 205:1593-9. 2008
    ..This study indicates that the antiinflammatory agent CNI-1493 can ameliorate the pathophysiology and cognitive defects in a murine model of AD...
  78. ncbi request reprint Cost effectiveness of pharmacotherapies in early Parkinson's disease
    Karla M Eggert
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    CNS Drugs 22:841-60. 2008
    ..Novel head-to-head comparisons considering the actual treatment guidelines are necessary to identify the most cost-effective alternative in treating de novo Parkinson's disease patients...
  79. doi request reprint Evaluation of the obesity genes FTO and MC4R and the type 2 diabetes mellitus gene TCF7L2 for contribution to stroke risk: The Mannheim-Heidelberg Stroke Study
    Yaroslav Winter
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Obes Facts 4:290-6. 2011
    ..The objective was to investigate the genetic markers related to obesity genes FTO and MC4R and the gene of type 2 diabetes mellitus TCF7L2 for their contribution to risk of stroke and transient ischemic attacks (TIA)...
  80. doi request reprint Role of MIF in inflammation and tumorigenesis
    Jan Philipp Bach
    Institute of Immunology, Philipps University Marburg, Marburg, Germany
    Oncology 75:127-33. 2008
    ..This review provides an overview of the involvement of MIF in both autoimmune disorders and tumorigenesis and summarizes the molecular action of MIF in this context...
  81. doi request reprint Theory of mind in Parkinson's disease and related basal ganglia disorders: a systematic review
    Maren Elisabeth Bodden
    Department of Neurology, Philipps University, Marburg 35039 Germany
    Mov Disord 25:13-27. 2010
    ..The purpose of this review is to provide an overview of research on ToM abilities in basal ganglia disorders, especially Parkinson's Disease and related disorders...
  82. doi request reprint Who was the man who discovered the "Lewy bodies"?
    Antonio M Rodrigues e Silva
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 25:1765-73. 2010
    ..This article gives a summary of Lewy's life and briefly presents his contribution to German and American neurology...
  83. ncbi request reprint [Cost and quality aspects in the treatment of Parkinson's disease]
    Thomas Muller
    Neurologische Klinik im St Josef Hospital, Ruhr Universitat Bochum
    Z Arztl Fortbild Qualitatssich 100:291-5. 2006
    ..The Parkinsonian patient should benefit from the scientific progress in the treatment of PD. This will improve quality of life and at least decrease the indirect costs of PD on the long term...
  84. doi request reprint Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)
    Oliver Riedel
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
    J Neurol 255:255-64. 2008
    ..Prevalence estimates of these complications are quite variable and are lacking for the outpatient care sector...
  85. ncbi request reprint Rate of clinical progression in Parkinson's disease. A prospective study
    Anette Schrag
    Department of Clinical Neurosciences, Royal Free Hospital, University College London, London, United Kingdom
    Mov Disord 22:938-45. 2007
    ..However, disability continues to deteriorate with advancing disease and with the development of disease complications that are likely to be related to additional extrastriatal pathology...