Research Topics
Genomes and Genes | Katja BeckerSummaryAffiliation: Philipps University Country: Germany Publications
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Publications
From regulatory problems in infancy to attention-deficit/hyperactivity disorder in childhood: a moderating role for the dopamine D4 receptor gene?Katja Becker
Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, Philipps University Marburg, Marburg, Germany
J Pediatr 156:798-803, 803.e1-803.e2. 2010..To examine whether the dopamine receptor D4 gene (DRD4) exon III VNTR moderates the risk of infants with regulatory disorders for developing attention-deficit/hyperactivity disorder (ADHD) later in childhood...
Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adultsArlette F Buchmann
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
J Psychiatr Res 43:1205-12. 2009....
Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adultsManfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Int J Neuropsychopharmacol 12:737-47. 2009..No evidence for GxE was obtained with regard to current stressful life events and trait anxiety. One possible source for the conflicting findings might be attributed to heterogeneity in depression phenotypes and environmental adversity...
Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphismManfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Biol Psychiatry 66:102-9. 2009..The present study aims to further explore G x E between 5-HTTLPR and exposure to psychosocial adversity on alcohol consumption in a high-risk community sample of young adults...
Genetic variation in dopamine pathways differentially associated with smoking progression in adolescenceManfred Laucht
Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, P O Box 122120, D 68072 Mannheim, Germany
J Am Acad Child Adolesc Psychiatry 47:673-81. 2008..To clarify the nature of the association between dopamine genes and smoking by examining whether genetic variability in components of the dopamine pathway could explain refined phenotypes in adolescent smoking progression...
The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-oldsBrigitte Schmid
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Addict Biol 14:489-99. 2009..Further studies are required to confirm these findings...
Evidence for epistasis between the 5-HTTLPR and the dopamine D4 receptor polymorphisms in externalizing behavior among 15-year-oldsSarah Hohmann
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
J Neural Transm 116:1621-9. 2009..This result suggests an effect of 5-HTTLPR on externalizing behavior in the presence of DRD4 7r but no effect in its absence...
Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptomsKatja Becker
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Pediatr 152:263-9. 2008....
Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sampleManfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Biol Psychiatry 61:87-92. 2007..The aim of this study was to examine whether allelic variants of the dopamine D4 receptor gene (DRD4) are associated with alcohol use in adolescents and to determine the extent to which these links are mediated by NS...
Visual exploratory behaviour in infancy and novelty seeking in adolescence: two developmentally specific phenotypes of DRD4?Manfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Child Psychol Psychiatry 47:1143-51. 2006..The present study was designed to investigate the association between visual exploratory behaviour in early infancy, novelty seeking in adolescence, and the dopamine D4 receptor (DRD4) genotype...
From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disordersAnne Kathrin Wermter
Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Strasse 6, Marburg, Germany
Eur Child Adolesc Psychiatry 19:199-210. 2010..In future we need larger, sufficiently powered studies that include a detailed and sophisticated characterization of both phenotype and the environmental risk...
Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sampleManfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Arch Gen Psychiatry 64:585-90. 2007..Recent evidence suggests that gene x environment interactions could explain the inconsistent findings of association studies relating the dopamine transporter (DAT1) gene with attention-deficit/hyperactivity disorder (ADHD)...
Rolandic spikes increase impulsivity in ADHD - a neuropsychological pilot studyMartin Holtmann
Department of Child and Adolescent Psychiatry and Psychotherapy, J W Goethe University, Frankfurt Main, Germany
Brain Dev 28:633-40. 2006....
Evaluation of the revised algorithm of Autism Diagnostic Observation Schedule (ADOS) in the diagnostic investigation of high-functioning children and adolescents with autism spectrum disordersInge Kamp-Becker
Department of Child and Adolescent Psychiatry, Philipps University Marburg, Marburg, Germany
Autism 17:87-102. 2013..As the ADOS is valid and reliable even for higher functioning ASD, the findings of the present study have been used to make recommendations regarding the best use of ADOS algorithms in a high-functioning sample...
Association of the DRD4 exon III polymorphism with smoking in fifteen-year-olds: a mediating role for novelty seeking?Manfred Laucht
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, D 68072 Mannheim, Germany
J Am Acad Child Adolesc Psychiatry 44:477-84. 2005....
Molecular genetics of attention-deficit/hyperactivity disorder: an overviewTobias Banaschewski
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Eur Child Adolesc Psychiatry 19:237-57. 2010....
Narrative competence and internal state language of children with Asperger Syndrome and ADHDAnna Lena Rumpf
Department of German Language Studies, Clinical Linguistics, Philipps University Marburg, D 35032 Marburg, Germany
Res Dev Disabil 33:1395-407. 2012..In conclusion, the two clinical groups differed from the HC group on a number of features, and a less frequent reference to cognitive states was identified for the children with AS...
Early identification of Asperger syndrome in young childrenWiebke Hoffmann
Department of Child and Adolescent Psychiatry, Philipps University Marburg, D 35033 Marburg, Germany
Res Dev Disabil 34:640-9. 2013..92) and specificity was also excellent (.90). Eight items with high discriminatory power allowed sensitive and economic screening for young children with suspected AS...
Categorical and dimensional structure of autism spectrum disorders: the nosologic validity of Asperger SyndromeInge Kamp-Becker
Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University Marburg, Hans Sachs Strasse 6, Marburg, Germany
J Autism Dev Disord 40:921-9. 2010..On the contrary, it provides evidence that e.g. AS and autism are not qualitatively distinct disorders, but rather different quantitative manifestations of the same disorder...
Increased frequency of rolandic spikes in ADHD childrenMartin Holtmann
Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, Mannheim, Germany
Epilepsia 44:1241-4. 2003..ADHD patients with and without discharges are compared regarding age at admission, sex, global functioning, and distribution of ADHD subtypes...
