Research Topics
| Stefanie PöggelerSummaryCountry: Germany Publications
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Detail Information
Publications
Phylogenetic relationships between mating-type sequences from homothallic and heterothallic ascomycetesS Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
Curr Genet 36:222-31. 1999..Strong inter-relationships were found among homothallic, as well as among heterothallic, members of both genera, indicating that in each genus a change from one reproductive strategy to another might result from one single event...
Two pheromone precursor genes are transcriptionally expressed in the homothallic ascomycete Sordaria macrosporaS Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
Curr Genet 37:403-11. 2000..macrospora. This is the first description of pheromone precursor genes encoded by a homothallic fungus. Southern-hybridization experiments indicated that ppg1 and ppg2 homologues are also present in other homothallic ascomycetes...
Mating-type genes for classical strain improvements of ascomycetesS Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
Appl Microbiol Biotechnol 56:589-601. 2001..In addition, this review describes how the availability of mating-type sequences allows the investigation of key issues concerning genetic and phylogenetic analyses of fungal species...
Identification of transcriptionally expressed pheromone receptor genes in filamentous ascomycetesS Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
Gene 280:9-17. 2001..crassa, expression of the receptor genes does not occur in a mating type specific manner. Thus, filamentous ascomycetes appear to posses and express pheromone receptor genes...
Genomic evidence for mating abilities in the asexual pathogen Aspergillus fumigatusStefanie Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
Curr Genet 42:153-60. 2002..cerevisiae, respectively. The identification of these homologues suggests the existence of a sexual cycle in A. fumigatus...
A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatinStefanie Pöggeler
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
Eukaryot Cell 3:232-40. 2004..Our data strongly suggest that an evolutionarily conserved cellular process controlling eukaryotic cell differentiation may regulate fruiting body formation...
Three alpha-subunits of heterotrimeric G proteins and an adenylyl cyclase have distinct roles in fruiting body development in the homothallic fungus Sordaria macrosporaJens Kamerewerd
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
Genetics 180:191-206. 2008..From the sum of all our data, we propose a model for how different Galpha-subunits interact with pheromone receptors, adenylyl cyclase, and STE12 and thus cooperatively regulate sexual development in S. macrospora...
Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenumJulia Böhm
Christian Doppler Laboratory for Fungal Biotechnology, Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
Proc Natl Acad Sci U S A 110:1476-81. 2013..These discoveries of a sexual cycle and MAT gene function are likely to be of broad relevance for manipulation of other asexual fungi of economic importance...
Highly efficient generation of signal transduction knockout mutants using a fungal strain deficient in the mammalian ku70 orthologStefanie Pöggeler
Ruhr Universitat Bochum, Lehrstuhl für Allgemeine und Molekulare Botanik, 44780 Bochum, Germany
Gene 378:1-10. 2006..PCR generated deletion constructs containing 1000 bp of homologous flanking sequence resulted in a drastically increased gene targeting efficiency. As a consequence, almost all transformants generated carried a disrupted target gene...
De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora, a model organism for fungal morphogenesisMinou Nowrousian
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
PLoS Genet 6:e1000891. 2010....
Versatile EGFP reporter plasmids for cellular localization of recombinant gene products in filamentous fungiStefanie Pöggeler
Department for General and Molecular Botany, Ruhr University Bochum, 44780 Bochum, Germany
Curr Genet 43:54-61. 2003..In the latter, the heterologous egfp gene is stably inherited during meiotic divisions, as can easily be seen from fluorescent ascospores...
A homologue of the human STRIPAK complex controls sexual development in fungiSandra Bloemendal
Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Universitatsstr 150, 44780 Bochum, Germany
Mol Microbiol 84:310-23. 2012..In S. macrospora, truncation of PRO11 and PRO22 leads to distinct defects in sexual development and cell fusion, indicating a role for the fungal STRIPAK complex in both processes...
Eighty years after its discovery, Fleming's Penicillium strain discloses the secret of its sexBirgit Hoff
Ruhr Universitat Bochum, Lehrstuhl für Allgemeine und Molekulare Botanik, Universitatsstr 150, 44780 Bochum, Germany
Eukaryot Cell 7:465-70. 2008..This discovery extends options for industrial strain improvement programs using conventional genetical approaches...
