Stefanie Pöggeler

Summary

Country: Germany

Publications

  1. ncbi request reprint Phylogenetic relationships between mating-type sequences from homothallic and heterothallic ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    Curr Genet 36:222-31. 1999
  2. ncbi request reprint Two pheromone precursor genes are transcriptionally expressed in the homothallic ascomycete Sordaria macrospora
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
    Curr Genet 37:403-11. 2000
  3. ncbi request reprint Mating-type genes for classical strain improvements of ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
    Appl Microbiol Biotechnol 56:589-601. 2001
  4. ncbi request reprint Identification of transcriptionally expressed pheromone receptor genes in filamentous ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Gene 280:9-17. 2001
  5. ncbi request reprint Genomic evidence for mating abilities in the asexual pathogen Aspergillus fumigatus
    Stefanie Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Curr Genet 42:153-60. 2002
  6. pmc A MADS box protein interacts with a mating-type protein and is required for fruiting body development in the homothallic ascomycete Sordaria macrospora
    Nicole Nolting
    Department of General and Molecular Botany, Ruhr University of Bochum, ND6 161, Universitatsstrasse 150, 44780 Bochum, Germany
    Eukaryot Cell 5:1043-56. 2006
  7. pmc Functional characterization of an alpha-factor-like Sordaria macrospora peptide pheromone and analysis of its interaction with its cognate receptor in Saccharomyces cerevisiae
    Severine Mayrhofer
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat, Bochum, Germany
    Eukaryot Cell 4:661-72. 2005
  8. pmc A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatin
    Stefanie Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Eukaryot Cell 3:232-40. 2004
  9. ncbi request reprint Comparative sequence analysis of Sordaria macrospora and Neurospora crassa as a means to improve genome annotation
    Minou Nowrousian
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780, Bochum, Germany
    Fungal Genet Biol 41:285-92. 2004
  10. pmc Three alpha-subunits of heterotrimeric G proteins and an adenylyl cyclase have distinct roles in fruiting body development in the homothallic fungus Sordaria macrospora
    Jens Kamerewerd
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
    Genetics 180:191-206. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Phylogenetic relationships between mating-type sequences from homothallic and heterothallic ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    Curr Genet 36:222-31. 1999
    ..Strong inter-relationships were found among homothallic, as well as among heterothallic, members of both genera, indicating that in each genus a change from one reproductive strategy to another might result from one single event...
  2. ncbi request reprint Two pheromone precursor genes are transcriptionally expressed in the homothallic ascomycete Sordaria macrospora
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
    Curr Genet 37:403-11. 2000
    ..macrospora. This is the first description of pheromone precursor genes encoded by a homothallic fungus. Southern-hybridization experiments indicated that ppg1 and ppg2 homologues are also present in other homothallic ascomycetes...
  3. ncbi request reprint Mating-type genes for classical strain improvements of ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Germany
    Appl Microbiol Biotechnol 56:589-601. 2001
    ..In addition, this review describes how the availability of mating-type sequences allows the investigation of key issues concerning genetic and phylogenetic analyses of fungal species...
  4. ncbi request reprint Identification of transcriptionally expressed pheromone receptor genes in filamentous ascomycetes
    S Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Gene 280:9-17. 2001
    ..crassa, expression of the receptor genes does not occur in a mating type specific manner. Thus, filamentous ascomycetes appear to posses and express pheromone receptor genes...
  5. ncbi request reprint Genomic evidence for mating abilities in the asexual pathogen Aspergillus fumigatus
    Stefanie Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Curr Genet 42:153-60. 2002
    ..cerevisiae, respectively. The identification of these homologues suggests the existence of a sexual cycle in A. fumigatus...
  6. pmc A MADS box protein interacts with a mating-type protein and is required for fruiting body development in the homothallic ascomycete Sordaria macrospora
    Nicole Nolting
    Department of General and Molecular Botany, Ruhr University of Bochum, ND6 161, Universitatsstrasse 150, 44780 Bochum, Germany
    Eukaryot Cell 5:1043-56. 2006
    ..macrospora mating-type locus. These results suggest that the S. macrospora MCM1 protein is involved in the transcriptional regulation of mating-type-specific genes as well as in fruiting body development...
  7. pmc Functional characterization of an alpha-factor-like Sordaria macrospora peptide pheromone and analysis of its interaction with its cognate receptor in Saccharomyces cerevisiae
    Severine Mayrhofer
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat, Bochum, Germany
    Eukaryot Cell 4:661-72. 2005
    ..However, loss of the ppg1 gene does not affect vegetative growth or fertility. Finally, we established the yeast assay as an easy and useful system for analyzing pheromone production in developmental mutants of S. macrospora...
  8. pmc A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatin
    Stefanie Pöggeler
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Eukaryot Cell 3:232-40. 2004
    ..Our data strongly suggest that an evolutionarily conserved cellular process controlling eukaryotic cell differentiation may regulate fruiting body formation...
  9. ncbi request reprint Comparative sequence analysis of Sordaria macrospora and Neurospora crassa as a means to improve genome annotation
    Minou Nowrousian
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780, Bochum, Germany
    Fungal Genet Biol 41:285-92. 2004
    ..Our analysis indicates that due to the high degree of sequence similarity and conservation of overall genomic organization, S. macrospora sequence information can be used to simplify the annotation of the N. crassa genome...
  10. pmc Three alpha-subunits of heterotrimeric G proteins and an adenylyl cyclase have distinct roles in fruiting body development in the homothallic fungus Sordaria macrospora
    Jens Kamerewerd
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
    Genetics 180:191-206. 2008
    ..From the sum of all our data, we propose a model for how different Galpha-subunits interact with pheromone receptors, adenylyl cyclase, and STE12 and thus cooperatively regulate sexual development in S. macrospora...
  11. ncbi request reprint Functional analysis of the C6 zinc finger gene pro1 involved in fungal sexual development
    Sandra Masloff
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    Fungal Genet Biol 36:107-16. 2002
    ..crassa genome, we identified hpro1A, another transcriptionally expressed gene, with a similarity of 40% to the pro1 genes, which is present as a single copy gene in N. crassa as well as in S. macrospora...
  12. pmc Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenum
    Julia Böhm
    Christian Doppler Laboratory for Fungal Biotechnology, Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    Proc Natl Acad Sci U S A 110:1476-81. 2013
    ..These discoveries of a sexual cycle and MAT gene function are likely to be of broad relevance for manipulation of other asexual fungi of economic importance...
  13. ncbi request reprint Highly efficient generation of signal transduction knockout mutants using a fungal strain deficient in the mammalian ku70 ortholog
    Stefanie Pöggeler
    Ruhr Universitat Bochum, Lehrstuhl für Allgemeine und Molekulare Botanik, 44780 Bochum, Germany
    Gene 378:1-10. 2006
    ..PCR generated deletion constructs containing 1000 bp of homologous flanking sequence resulted in a drastically increased gene targeting efficiency. As a consequence, almost all transformants generated carried a disrupted target gene...
  14. pmc De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora, a model organism for fungal morphogenesis
    Minou Nowrousian
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
    PLoS Genet 6:e1000891. 2010
    ....
  15. pmc The genome and development-dependent transcriptomes of Pyronema confluens: a window into fungal evolution
    Stefanie Traeger
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Bochum, Germany
    PLoS Genet 9:e1003820. 2013
    ..confluens and the Sordariomycete Sordaria macrospora. The P. confluens pro44 gene (PCON_06721) was used to complement the S. macrospora pro44 deletion mutant, showing functional conservation of this developmental regulator...
  16. ncbi request reprint A STE12 homologue of the homothallic ascomycete Sordaria macrospora interacts with the MADS box protein MCM1 and is required for ascosporogenesis
    Nicole Nolting
    Department of General and Molecular Botany, Ruhr University of Bochum, 44780 Bochum, Germany
    Mol Microbiol 62:853-68. 2006
    ..However, ascus and ascospore development are highly impaired by the Deltaste12 mutation. Our data provide another example of the functional divergence within the fungal STE12 transcription factor family...
  17. ncbi request reprint Versatile EGFP reporter plasmids for cellular localization of recombinant gene products in filamentous fungi
    Stefanie Pöggeler
    Department for General and Molecular Botany, Ruhr University Bochum, 44780 Bochum, Germany
    Curr Genet 43:54-61. 2003
    ..In the latter, the heterologous egfp gene is stably inherited during meiotic divisions, as can easily be seen from fluorescent ascospores...
  18. doi request reprint A homologue of the human STRIPAK complex controls sexual development in fungi
    Sandra Bloemendal
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, Universitatsstr 150, 44780 Bochum, Germany
    Mol Microbiol 84:310-23. 2012
    ..In S. macrospora, truncation of PRO11 and PRO22 leads to distinct defects in sexual development and cell fusion, indicating a role for the fungal STRIPAK complex in both processes...
  19. pmc Eighty years after its discovery, Fleming's Penicillium strain discloses the secret of its sex
    Birgit Hoff
    Ruhr Universitat Bochum, Lehrstuhl für Allgemeine und Molekulare Botanik, Universitatsstr 150, 44780 Bochum, Germany
    Eukaryot Cell 7:465-70. 2008
    ..This discovery extends options for industrial strain improvement programs using conventional genetical approaches...
  20. ncbi request reprint Protein splicing of PRP8 mini-inteins from species of the genus Penicillium
    Skander Elleuche
    Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr Universitat Bochum, 44780, Bochum, Germany
    Appl Microbiol Biotechnol 72:959-67. 2006
    ..The GFP assay should be valuable as a screening system for protein splicing inhibitors as potential antimycotic agents and as tools for studying the mechanism of protein splicing of fungal mini-inteins...