Research Topics
Genomes and GenesSpecies | B PfuhlmannSummaryCountry: Germany Publications
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Publications
Is Ankyrin a genetic risk factor for psychiatric phenotypes?Alejandro Gella
Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Josep Trueta s n, Sant Cugat del Vallès 08195, Spain
BMC Psychiatry 11:103. 2011..Within the debate on common susceptibility genes for schizophrenia and bipolar disorder, we tried to investigate common findings by analyzing association of ANK3 with schizophrenia, bipolar disorder and unipolar depression...
The DAOA/G30 locus and affective disorders: haplotype based association study in a polydiagnostic approachMicha Gawlik
Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, Wurzburg, Germany
BMC Psychiatry 10:59. 2010....
The different conceptions of catatonia: historical overview and critical discussionB Pfuhlmann
Department of Psychiatry, University of Wurzburg, Germany
Eur Arch Psychiatry Clin Neurosci 251:I4-7. 2001..Based on a precise differentiation of psychomotor disturbances, two essentially different forms of catatonic psychoses have been separated, systematic and periodic catatonias which differ in symptomatology, prognosis and treatment...
Postpartum psychoses: prognosis, risk factors, and treatmentBruno Pfuhlmann
Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, D 97080 Wurzburg, Germany
Curr Psychiatry Rep 4:185-90. 2002..Applying estradiol after delivery may be beneficial and safe, but further studies are necessary to clarify these issues...
Cycloid psychoses are not part of a bipolar affective spectrum: results of a controlled family studyB Pfuhlmann
Department of Psychiatry and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, D 97080 Wuerzburg, Germany
J Affect Disord 83:11-9. 2004..To further clarify this issue a controlled family study was undertaken...
[Cycloid psychoses as atypical manic-depressive disorders. Results of a family study]B Jabs
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
Nervenarzt 77:1096-100, 1102-4. 2006..Whereas a growing body of evidence suggests that cycloid psychoses have to be separated from schizophrenic psychoses, their relations to bipolar affective disorder are less clear...
ZDHHC8 as a candidate gene for schizophrenia: analysis of a putative functional intronic marker in case-control and family-based association studiesThomas Faul
Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
BMC Psychiatry 5:35. 2005....
Towards the genetic basis of periodic catatonia: pedigree sample for genome scan I and IIG Stober
Department of Psychiatry and Psychotherapy, University of Wurzburg, Germany
Eur Arch Psychiatry Clin Neurosci 251:I25-30. 2001....
Gender differences and age of onset in the catatonic subtypes of schizophreniaG Stober
Department of Psychiatry, University of Wurzburg, Germany
Psychopathology 31:307-12. 1998..8% in late-onset probands. Our findings substantiate the hypothesis that periodic catatonia is a clinically homogenous disorder with a major gene effect and an age at onset which is to a large extent genetically determined...
[Comparative study of life quality in patients with cycloid and schizophrenic psychoses]B Jabs
Klinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg, Wurzburg
Nervenarzt 75:460-6. 2004..Cycloid psychoses represent a nosological entity not adequately recognised by contemporary psychiatry. They show full recovery after each episode and thus have a favourable prognosis...
[Hypochondriacal euphoria as a special form of monopolar affective psychosis]B E Jabs
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg
Psychiatr Prax 28:29-34. 2001..Based upon subtle observation of signs and course over many years, Karl Leonhard developed a concept of affective psychoses that permits a distinction of monopolar from bipolar forms, e.g. monopolar manias and euphoric euphorias...
[Clinical aspects of puerperal psychoses. Review with 3 case examples]A J Fallgatter
Klinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg
Nervenarzt 73:680-5. 2002..However, this sophisticated therapeutic strategy requires close cooperation between gynecologists and psychiatrists...
Cycloid psychoses -- from clinical concepts to biological foundationsB E Jabs
Department of Psychiatry, Julius Maximilians University, Wurzburg, Federal Republic of Germany
J Neural Transm 109:907-19. 2002..Finally, future perspectives for the field of biological psychiatry are proposed fostering the heuristics of Leonhard's nosology...
[Kleptomania: clinical and legal aspects]B E Jabs
Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Würzburg, Wuerzburg
Fortschr Neurol Psychiatr 72:21-5. 2004..The present article gives an overview of the most important aetiopathogenetic viewpoints about kleptomania and discusses their nosological, therapeutical and legal implications...
Improvement of prefrontal brain function in endogenous psychoses under atypical antipsychotic treatmentAnn Christine Ehlis
Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
Neuropsychopharmacology 32:1669-77. 2007....
Differences in quality of life and course of illness between cycloid and schizophrenic psychoses - a comparative studyBurkhard Emanuel Jabs
Department of Psychiatry, Julius Maximilians University, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
World J Biol Psychiatry 5:136-42. 2004..Cycloid psychoses represent a nosological entity not adequately recognised by contemporary psychiatry. They present with full recoveries after each psychotic episode and, thus, have a favourable prognosis...
The concept of hebephrenia over the course of time with particular reference to the Wernicke-Kleist-Leonhard SchoolBurkhard Emanuel Jabs
Department of Psychiatry, Julius Maximilians University, Wurzburg, Germany
World J Biol Psychiatry 3:200-6. 2002..This concept of hebephrenia seems to be more appropriate to demarcate a homogeneous subtype which can be the subject of further promising research to clarify aetiology and nosology of schizophrenic spectrum psychoses...
Sensory gating deficit in a subtype of chronic schizophrenic patientsThomas M Ringel
Psychiatric Neurophysiology, Department of Psychiatry and Psychotherapy, University Hospital of Wurzburg, Fuchsleinstrasse 15, 97080 Wuerzburg, Germany
Psychiatry Res 125:237-45. 2004..Both subtype of schizophrenia and current form of psychopathology appear to be related to the presence or absence of abnormal sensory gating...
Susceptibility to neuroleptic-induced parkinsonism--age and increased substantia nigra echogenicity as putative risk factorsBurkhard Emanuel Jabs
Department of Psychiatry, Julius Maximilians University, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
Eur Psychiatry 18:177-81. 2003..Previous transcranial sonography (TCS) findings of the substantia nigra (SN) in patients with idiopathic Parkinson's disease suggest a correlation of echogenicity with nigrostriatal dysfunction...
Family-based study of markers at the 5'-flanking region of the human dopamine transporter gene reveals potential association with schizophrenic psychosesGerald Stober
Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstr 15, 97080, Wurzburg, Germany
Eur Arch Psychiatry Clin Neurosci 256:422-7. 2006..We propose replication in extended samples and examination of the functional relevance of the associated genotypes on human dopamine transporter expression...
Homocysteinemia in psychiatric disorders: association with dementia and depression, but not schizophrenia in female patientsA Reif
Department of Psychiatry and Psychotherapy, Julius Maximilians University Würzburg, Germany
J Neural Transm 110:1401-11. 2003..9+/-3.8 micromol/l), especially in elderly subjects. We thus suggest that homocysteinemia, at least in females, is an unspecific risk factor for organic brain disorders, but not endogenous psychoses...
Case report: intoxication with high dose of long-acting methylphenidate (Concerta(®)) in a suicidal 14-year-old girlK Klampfl
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Germany
Atten Defic Hyperact Disord 2:221-4. 2010..Thus this case report suggests that patients intoxicated with high dose long-acting MPH formulations can recover without sequelae when managed properly...
Homocysteinemia as well as methylenetetrahydrofolate reductase polymorphism are associated with affective psychosesAndreas Reif
Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, Julius Maximilians University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
Prog Neuropsychopharmacol Biol Psychiatry 29:1162-8. 2005..In conclusion, we suggest that in females homocysteinemia is an unspecific risk factor for organic brain disorders like dementia, and possibly depression, but not for schizophrenia...
Serum concentrations, therapeutic response and side effects in children and adolescents with impulsive-aggressive symptoms during risperidone therapyK Klampfl
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
Pharmacopsychiatry 43:58-65. 2010....
Differences in substantia nigra echogenicity of nosological subtypes within the schizophrenic spectrum. A preliminary transcranial ultrasound studyB E Jabs
Department of Psychiatry, Julius Maximilians University, Wurzburg, Germany
Neuropsychobiology 44:183-6. 2001..Here, transcranial sonography (TCS) was used to test for differences in the susceptibility to NIP related to the echogenicity of the substantia nigra (SN) in different schizophrenic subforms...
The effect of age, sex, smoking and co-medication on serum levels of venlafaxine and O-desmethylvenlafaxine under naturalistic conditionsS Unterecker
Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
Pharmacopsychiatry 45:229-35. 2012..In this study we examined the influence of age, sex, smoking, and co-medication on serum levels of VEN and its metabolite O-desmethylvenlafaxine (ODVEN) in patients treated with VEN under naturalistic conditions...
Neuroleptic malignant syndrome in Kufs' diseaseA Reif
Department of Psychiatry and Psychotherapy, Julius Maximilians University Würzburg, Germany
J Neurol Neurosurg Psychiatry 74:385-7. 2003..Collectively the results argued for an involvement of the muscle in neuroleptic malignant syndrome at least in ANCL...
Toxic clozapine serum levels during acute urinary tract infection: a case reportJulia Jecel
Psychiatric Department of the Julius-Maximilians, , , 97080 Wuerzburg, Germany
Eur J Clin Pharmacol 60:909-10. 2005
Duloxetine serum concentrations and clinical effects. Data from a therapeutic drug monitoring (TDM) surveyC Waldschmitt
Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
Pharmacopsychiatry 42:189-93. 2009..The aim of this study was to relate drug concentrations in serum and clinical effects in patients treated with the new antidepressant duloxetine...
Delusional paralysis: an unusual variant of Cotard's syndromeAndreas Reif
Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, DE 97080 Würzburg, Germany
Psychopathology 36:218-20. 2003..Upon ECT, symptoms rapidly improved. Psychopathological implications and the nosological position of Cotard's syndrome are discussed...
Duplication 15q14 --> pter: a rare chromosomal abnormality underlying bipolar affective disorderAndreas Reif
Department of Psychiatry and Psychotherapy, Julius Maximilians University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
Eur Psychiatry 19:179-81. 2004..Possible implications of this rare chromosomal abnormality with regards to psychiatric disorders are discussed, with emphasis on recent evidence suggesting chromosome 15q13-15 as a susceptibility locus for psychosis...
Venlafaxine and reversible blepharoedemaAndreas Reif
Int J Neuropsychopharmacol 5:413-4. 2002
