G Pecher

Summary

Country: Germany

Publications

  1. ncbi request reprint Generation of an immortalized human CD4+ T cell clone inhibiting tumor growth in mice
    G Pecher
    AG Molecular Gene and Immunotherapy, Humboldt University Berlin, Charite Campus Mitte, Hessische Strasse 3 4, Berlin, 10115, Germany
    Biochem Biophys Res Commun 283:738-42. 2001
  2. ncbi request reprint Mucin gene (MUC1) transfer into human dendritic cells by cationic liposomes and recombinant adenovirus
    G Pecher
    Charite, Humboldt University Berlin, AG Molecular Gene and Immunotherapy, Germany
    Anticancer Res 21:2591-6. 2001
  3. ncbi request reprint Efficient cryopreservation of dendritic cells transfected with cDNA of a tumour antigen for clinical application
    G Pecher
    Humboldt University Berlin, Charite Campus Mitte, AG Molecular Gene and Immunotherapy, Hessische Str 3 4, 10115 Berlin, Germany
    Biotechnol Appl Biochem 34:161-6. 2001
  4. ncbi request reprint Long-term tumor growth suppression in mice immunized with naked DNA of the human tumor antigen mucin (MUC1)
    H Johnen
    Humboldt-University Berlin, , AG Molecular Gene- and Immunotherapy, Berlin, Germany
    Cancer Immunol Immunother 50:356-60. 2001
  5. ncbi request reprint Wilms' tumor gene (WT1) expression in lung cancer, colon cancer and glioblastoma cell lines compared to freshly isolated tumor specimens
    H D Menssen
    Medizinische Klinik III, Hämatologie, Onkologie und Transfusionsmedizin, Benjamin Franklin Klinik der Freien Universität, Berlin, Germany
    J Cancer Res Clin Oncol 126:226-32. 2000

Detail Information

Publications5

  1. ncbi request reprint Generation of an immortalized human CD4+ T cell clone inhibiting tumor growth in mice
    G Pecher
    AG Molecular Gene and Immunotherapy, Humboldt University Berlin, Charite Campus Mitte, Hessische Strasse 3 4, Berlin, 10115, Germany
    Biochem Biophys Res Commun 283:738-42. 2001
    ..SITAM cells provide an unlimited source of clonal T cells for analysis of tumor recognition and may be of help in TCR-targeted immunotherapy...
  2. ncbi request reprint Mucin gene (MUC1) transfer into human dendritic cells by cationic liposomes and recombinant adenovirus
    G Pecher
    Charite, Humboldt University Berlin, AG Molecular Gene and Immunotherapy, Germany
    Anticancer Res 21:2591-6. 2001
    ..Mucin, encoded by the gene MUC1, is a human tumor antigen expressed in breast, pancreatic and ovarian cancers. Therefore, MUC1-transfected DC would be an attractive tool in constructing cancer vaccines...
  3. ncbi request reprint Efficient cryopreservation of dendritic cells transfected with cDNA of a tumour antigen for clinical application
    G Pecher
    Humboldt University Berlin, Charite Campus Mitte, AG Molecular Gene and Immunotherapy, Hessische Str 3 4, 10115 Berlin, Germany
    Biotechnol Appl Biochem 34:161-6. 2001
    ..The stimulating capacity of a mixed lymphocyte culture was also preserved. These findings offer an efficient method for the cryopreservation of DCs for use in clinical trials...
  4. ncbi request reprint Long-term tumor growth suppression in mice immunized with naked DNA of the human tumor antigen mucin (MUC1)
    H Johnen
    Humboldt-University Berlin, , AG Molecular Gene- and Immunotherapy, Berlin, Germany
    Cancer Immunol Immunother 50:356-60. 2001
    ..These encouraging results, showing long-term protection against tumor growth, indicate the potential usefulness of naked DNA vaccination for clinical immunotherapy...
  5. ncbi request reprint Wilms' tumor gene (WT1) expression in lung cancer, colon cancer and glioblastoma cell lines compared to freshly isolated tumor specimens
    H D Menssen
    Medizinische Klinik III, Hämatologie, Onkologie und Transfusionsmedizin, Benjamin Franklin Klinik der Freien Universität, Berlin, Germany
    J Cancer Res Clin Oncol 126:226-32. 2000
    ..From this evidence, testing for WT1 expression is not clinically relevant for colon cancer, lung cancer, or glioblastoma patients. WT1 expression in cancer cell lines can probably be attributed to optimized in vitro growth conditions...