Ilse Wieland

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. pmc The impact of CFNS-causing EFNB1 mutations on ephrin-B1 function
    Roman Makarov
    Institut fur Humangenetik, Universitatsklinikum, Otto von Guericke Universitat, Magdeburg, Germany
    BMC Med Genet 11:98. 2010
  2. ncbi request reprint Dissecting the molecular mechanisms in craniofrontonasal syndrome: differential mRNA expression of mutant EFNB1 and the cellular mosaic
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Eur J Hum Genet 16:184-91. 2008
  3. pmc Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat Magdeburg, 39120 Magdeburg, Germany
    Am J Hum Genet 74:1209-15. 2004
  4. ncbi request reprint Twenty-six novel EFNB1 mutations in familial and sporadic craniofrontonasal syndrome (CFNS)
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Hum Mutat 26:113-8. 2005
  5. ncbi request reprint The heterozygous LMNA mutation p.R471G causes a variable phenotype with features of two types of familial partial lipodystrophy
    Petra Muschke
    Institute of Human Genetics, Otto von Guericke University, Magdeburg, Germany
    Am J Med Genet A 143:2810-4. 2007
  6. ncbi request reprint High incidence of familial breast cancer segregates with constitutional t(11;22)(q23;q11)
    Ilse Wieland
    , , Magdeburg, Germany
    Genes Chromosomes Cancer 45:945-9. 2006
  7. ncbi request reprint Clinical and genetic aspects of craniofrontonasal syndrome: towards resolving a genetic paradox
    Peter Wieacker
    Institut fur Humangenetik, Otto von Guericke Universitat, Leipziger Str 44, D 39120 Magdeburg, Germany
    Mol Genet Metab 86:110-6. 2005
  8. ncbi request reprint Further delineation of Wittwer syndrome and refinement of the mapping region
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Am J Med Genet A 116:57-60. 2003
  9. ncbi request reprint Ectopic expression of DICE1 suppresses tumor cell growth
    Ilse Wieland
    Institute of Human Genetics, Otto von Guericke Universitat, Magdeburg, Germany
    Oncol Rep 12:207-11. 2004

Collaborators

Detail Information

Publications9

  1. pmc The impact of CFNS-causing EFNB1 mutations on ephrin-B1 function
    Roman Makarov
    Institut fur Humangenetik, Universitatsklinikum, Otto von Guericke Universitat, Magdeburg, Germany
    BMC Med Genet 11:98. 2010
    ..406 + 2T > C and two missense mutations p.P54L and p.T111I. Both missense mutations are located in the extracellular ephrin domain involved in Eph-ephrin-B1 recognition and higher order complex formation...
  2. ncbi request reprint Dissecting the molecular mechanisms in craniofrontonasal syndrome: differential mRNA expression of mutant EFNB1 and the cellular mosaic
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Eur J Hum Genet 16:184-91. 2008
    ....
  3. pmc Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat Magdeburg, 39120 Magdeburg, Germany
    Am J Hum Genet 74:1209-15. 2004
    ..In all cases, mutations were found consistently in obligate male carriers, clinically affected males, and affected heterozygous females. We conclude that mutations in EFNB1 cause CFNS...
  4. ncbi request reprint Twenty-six novel EFNB1 mutations in familial and sporadic craniofrontonasal syndrome (CFNS)
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Hum Mutat 26:113-8. 2005
    ....
  5. ncbi request reprint The heterozygous LMNA mutation p.R471G causes a variable phenotype with features of two types of familial partial lipodystrophy
    Petra Muschke
    Institute of Human Genetics, Otto von Guericke University, Magdeburg, Germany
    Am J Med Genet A 143:2810-4. 2007
    ..The sister and father of the proband had the same mutation. The sister was more mildly affected and the father was apparently unaffected, demonstrating variable expressivity and reduced penetrance for this mutation...
  6. ncbi request reprint High incidence of familial breast cancer segregates with constitutional t(11;22)(q23;q11)
    Ilse Wieland
    , , Magdeburg, Germany
    Genes Chromosomes Cancer 45:945-9. 2006
    ....
  7. ncbi request reprint Clinical and genetic aspects of craniofrontonasal syndrome: towards resolving a genetic paradox
    Peter Wieacker
    Institut fur Humangenetik, Otto von Guericke Universitat, Leipziger Str 44, D 39120 Magdeburg, Germany
    Mol Genet Metab 86:110-6. 2005
    ..The more severe manifestation in females may be explained by cellular interference that is caused by the combination of ephrin ligand/receptor promiscuity and the consequences of random X inactivation in distinct cellular compartments...
  8. ncbi request reprint Further delineation of Wittwer syndrome and refinement of the mapping region
    Ilse Wieland
    Institut fur Humangenetik, Otto von Guericke Universitat, Magdeburg, Germany
    Am J Med Genet A 116:57-60. 2003
    ..However, deletion analysis of identified genes and ESTs in the critical interval for Wittwer syndrome showed no loss of the corresponding marker sequences in the patients...
  9. ncbi request reprint Ectopic expression of DICE1 suppresses tumor cell growth
    Ilse Wieland
    Institute of Human Genetics, Otto von Guericke Universitat, Magdeburg, Germany
    Oncol Rep 12:207-11. 2004
    ..These results demonstrate that DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I signaling...