F R Wiedemann

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. ncbi request reprint Evaluation of methods for the determination of mitochondrial respiratory chain enzyme activities in human skeletal muscle samples
    F R Wiedemann
    Department of Epileptology, Department of Neurology, University Bonn Medical Center, Sigmund Freud Strasse 25, Bonn, D 53105, Germany
    Anal Biochem 279:55-60. 2000
  2. ncbi request reprint Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
    Falk R Wiedemann
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, USA
    J Neurochem 80:616-25. 2002
  3. ncbi request reprint Unusual presentations of patients with the mitochondrial MERRF mutation A8344G
    Falk R Wiedemann
    Klinik fur Neurologie, Otto von Guericke Universitat, D 39120 Magdeburg, Germany
    Clin Neurol Neurosurg 110:859-63. 2008
  4. ncbi request reprint The neurotrophin receptor TrkB is colocalized to mitochondrial membranes
    Falk R Wiedemann
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    Int J Biochem Cell Biol 38:610-20. 2006
  5. ncbi request reprint Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson's disease
    K Winkler-Stuck
    Klinik fur Neurologie, Otto von Guericke Universitat, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    J Neural Transm 112:499-518. 2005
  6. ncbi request reprint Short incubation with 2-methoxyestradiol kills malignant glioma cells independent of death receptor 5 upregulation
    S Braeuninger
    Institute of Neuropathology, Otto von Guericke University, Magdeburg, Germany
    Clin Neuropathol 24:175-83. 2005
  7. ncbi request reprint Analysis of a single nucleotide polymorphism in codon 388 of the FGFR4 gene in malignant gliomas
    Christian Mawrin
    Department of Neuropathology, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Cancer Lett 239:239-45. 2006
  8. ncbi request reprint Assessment of tumor cell invasion factors in gliomatosis cerebri
    Christian Mawrin
    Institut für Neuropathologie, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    J Neurooncol 73:109-15. 2005
  9. ncbi request reprint Single-cell analysis of mtDNA deletion levels in sporadic amyotrophic lateral sclerosis
    Christian Mawrin
    Department of Neuropathology, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Neuroreport 15:939-43. 2004
  10. doi request reprint Hypoxia increases activity of the BK-channel in the inner mitochondrial membrane and reduces activity of the permeability transition pore
    Yu Cheng
    Dept of Neurology, Otto von Guericke University, Magdeburg, Germany
    Cell Physiol Biochem 22:127-36. 2008

Detail Information

Publications10

  1. ncbi request reprint Evaluation of methods for the determination of mitochondrial respiratory chain enzyme activities in human skeletal muscle samples
    F R Wiedemann
    Department of Epileptology, Department of Neurology, University Bonn Medical Center, Sigmund Freud Strasse 25, Bonn, D 53105, Germany
    Anal Biochem 279:55-60. 2000
    ..Therefore, citrate synthase-normalized respiratory chain activities can serve as stable reference values for the determination of a putative mitochondrial defect in human skeletal muscle...
  2. ncbi request reprint Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
    Falk R Wiedemann
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, USA
    J Neurochem 80:616-25. 2002
    ....
  3. ncbi request reprint Unusual presentations of patients with the mitochondrial MERRF mutation A8344G
    Falk R Wiedemann
    Klinik fur Neurologie, Otto von Guericke Universitat, D 39120 Magdeburg, Germany
    Clin Neurol Neurosurg 110:859-63. 2008
    ..These data extend the phenotypic range associated with the MERRF syndrome. We suggest that the analysis of mtDNA could be of importance in many cases of unclear multisystem disorders in later life...
  4. ncbi request reprint The neurotrophin receptor TrkB is colocalized to mitochondrial membranes
    Falk R Wiedemann
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    Int J Biochem Cell Biol 38:610-20. 2006
    ..Our results imply that neurotrophins can be stored in mitochondria and possibly act as signalling molecules on mitochondria...
  5. ncbi request reprint Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson's disease
    K Winkler-Stuck
    Klinik fur Neurologie, Otto von Guericke Universitat, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    J Neural Transm 112:499-518. 2005
    ..Our data confirm the previously debated presence of a mild mitochondrial defect in skeletal muscle of patients with PD which is accompanied with an about 1.5 to 2-fold increase of point mutated mtDNA...
  6. ncbi request reprint Short incubation with 2-methoxyestradiol kills malignant glioma cells independent of death receptor 5 upregulation
    S Braeuninger
    Institute of Neuropathology, Otto von Guericke University, Magdeburg, Germany
    Clin Neuropathol 24:175-83. 2005
    ....
  7. ncbi request reprint Analysis of a single nucleotide polymorphism in codon 388 of the FGFR4 gene in malignant gliomas
    Christian Mawrin
    Department of Neuropathology, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Cancer Lett 239:239-45. 2006
    ..U87 cells (Arg/Gly(388)) did not show higher invasion than U138 cells (Gly(388)). This suggests that the FGFR4 codon 388 status does not play a major role in malignant gliomas...
  8. ncbi request reprint Assessment of tumor cell invasion factors in gliomatosis cerebri
    Christian Mawrin
    Institut für Neuropathologie, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    J Neurooncol 73:109-15. 2005
    ....
  9. ncbi request reprint Single-cell analysis of mtDNA deletion levels in sporadic amyotrophic lateral sclerosis
    Christian Mawrin
    Department of Neuropathology, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Neuroreport 15:939-43. 2004
    ..A PCR assay of serial DNA dilutions (10-fold) showed no CD level differences between motor neurons in S-ALS and controls. These data suggest that neuronal death in S-ALS is not associated with significant accumulation of mtDNA deletions...
  10. doi request reprint Hypoxia increases activity of the BK-channel in the inner mitochondrial membrane and reduces activity of the permeability transition pore
    Yu Cheng
    Dept of Neurology, Otto von Guericke University, Magdeburg, Germany
    Cell Physiol Biochem 22:127-36. 2008
    ..We therefore conclude that there is interaction between the mtBK and the PTP in a way that an open mtBK keeps the PTP closed. Thus, the response of mitochondrial ion channels to hypoxia could be interpreted as anti-apoptotic...