Affiliation: Otto-von-Guericke University
- Positron emission tomography and magnetic resonance imaging for cerebral involvement in patients with systemic lupus erythematosusM Sailer
Department of Neurophysiology, Otto von Guericke University, Magdeburg, Germany
J Neurol 244:186-93. 1997....
- Amantadine influences cognitive processing in patients with multiple sclerosisM Sailer
Department of Neurology II, Otto von Guericke University, Magdeburg, Germany
Pharmacopsychiatry 33:28-37. 2000..The present findings suggest that amantadine exerts beneficial effects on early cognitive processes in patients with MS, but appears to be limited to subjects with a longer duration of the disease...
- T1 lesion load and cerebral atrophy as a marker for clinical progression in patients with multiple sclerosis. A prospective 18 months follow-up studyM Sailer
Department of Neurology II, Otto von Guericke University, Magdeburg, Leipzigerstrasse 44, 39120 Magdeburg, Germany
Eur J Neurol 8:37-42. 2001..Although one should bear in mind some potential for reversibility due to inflammatory, oedematous lesions, these MR measures are a useful marker of progressive tissue damage and clinical progression in established MS...
- Influence of cerebral lesion volume and lesion distribution on event-related brain potentials in multiple sclerosisM Sailer
Dept of Neurology II, Otto von Guericke University, Magdeburg, Germany
J Neurol 248:1049-55. 2001....
- Focal thinning of the cerebral cortex in multiple sclerosisMichael Sailer
Otto von Guericke University Magdeburg, Leipzigerstrasse 44, 39120 Magdeburg, Germany
Brain 126:1734-44. 2003..The data provide new insight into the cortical pathology in multiple sclerosis patients, revealing focal cortical thinning beside an overall reduction of the cortical thickness with disease progression...
- The BDNF-Val66Met polymorphism: implications for susceptibility to multiple sclerosis and severity of diseaseS Lindquist
Department of Neurology II, Otto von Guericke University, Leipziger Str 44, 39120 Magdeburg, Germany
J Neuroimmunol 167:183-5. 2005..In order to test this hypothesis we genotyped the polymorphism in 951 UK multiple sclerosis trio families, but found no evidence for association before (p=0.63) or after stratification for clinical course (p=0.73)...
- Primary carnitine deficiency: adult onset lipid storage myopathy with a mild clinical courseS Vielhaber
Department of Neurology II, Otto von Guericke University Magdeburg, University Hospital, Magdeburg, Germany
J Clin Neurosci 11:919-24. 2004....
- Effect of creatine supplementation on metabolite levels in ALS motor corticesS Vielhaber
Department of Neurology II, University of Magdeburg Medical Center, Leipziger Strasse 44, Magdeburg, Germany
Exp Neurol 172:377-82. 2001....
- Histopathology and serial, multimodal magnetic resonance imaging in a multiple sclerosis variantS Lindquist
Department of Neurology, Otto von Guericke University, 39120 Magdeburg, Germany
Mult Scler 13:471-82. 2007..This is the first report comparing 1H-magnetic resonance spectroscopy, magnetization transfer and diffusion tensor imaging with histopathology in a patient with Balo's concentric sclerosis...
- A teaching model for endorectal ultrasound-guided biopsy and drainage of pararectal tumorsD Bussen
Dept of Surgery, Würzburg University School of Medicine, Wurzburg, Germany
Endoscopy 36:217-9. 2004..For a training program a lifelike model of the rectum was developed. It has been used by 780 participants in 20 training courses organized by the Surgical Department of University Hospital Würzburg...
- Escalating immunotherapy of multiple sclerosis--new aspects and practical applicationP Rieckmann
Dept of Neurology, Josef Schneider Str 11, 97080, Wurzburg, Germany
J Neurol 251:1329-39. 2004..Moreover, in long-term treated patients, secondary treatment failure should be identified by pre-planned follow-up examinations, and other treatment options should then be considered...
- Defective mitochondrial oxidative phosphorylation in myopathies with tubular aggregates originating from sarcoplasmic reticulumS Vielhaber
Department of Neurology, Otto-von-Guericke-University Magdeburg, Germany
J Neuropathol Exp Neurol 60:1032-40. 2001..Our findings indicate a functional link between mitochondrial dysfunction and the presence of TAs originating from the sarcoplasmic reticulum...
- Classifications and treatment responses in chronic immune-mediated demyelinating polyneuropathyB Tackenberg
Philipps University, Department of Neurology, Clinical Neuroimmunology Group, Marburg, Germany
Neurology 68:1622-9. 2007..Chronic immune-mediated demyelinating polyneuropathy (CIP) represents a heterogeneous pool of motor, sensory, sensorimotor, symmetric, or asymmetric syndromes...
- Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre studyD Pöhlau
Department of Neurology, Multiple Sclerosis Center, Kamillus Klinik Asbach, Germany
Mult Scler 13:1107-17. 2007..Treatment was generally well tolerated. It was concluded that monthly IVIG infusion could delay progression of disease in patients with PPMS, and that there was a trend in favour of IVIG treatment in patients with SPMS...
- Subgroups of the BENEFIT study: risk of developing MS and treatment effect of interferon beta-1bChris Polman
Vrije Universiteit Medical Centre, Amsterdam, The Netherlands
J Neurol 255:480-7. 2008..The BENEFIT study examined interferon beta (IFNB)-1b treatment in patients with clinically isolated syndrome (CIS) and > or = 2 clinically silent brain MRI lesions...
- [Cerebral and spinal MRI examination in patients with clinically isolated syndrome and definite multiple sclerosis]M Sailer
Neurologische Universitatsklinik, Otto von Guericke Universitat, Magdeburg
Rofo 180:994-1001. 2008..This diagnostic and prognostic information gained from MRI early in the disease course lead in 2001 to a revision of the diagnostic criteria...