Thoralf Opitz

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. ncbi request reprint Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitro
    Thoralf Opitz
    Department of Developmental Physiology, Institute for Physiology, Otto von Guericke University, 39120 Magdeburg, Germany
    J Neurophysiol 88:2196-206. 2002
  2. ncbi request reprint Activation of early silent synapses by spontaneous synchronous network activity limits the range of neocortical connections
    Thomas Voigt
    Department of Developmental Physiology, Otto von Guericke University, Institute of Physiology, 39120 Magdeburg, Germany
    J Neurosci 25:4605-15. 2005
  3. ncbi request reprint Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity
    Ana Dolabela de Lima
    Otto von Guericke Universitat, Medizinische Fakultat, Institut fur Physiologie, 39120 Magdeburg, Germany
    Eur J Neurosci 19:2931-43. 2004
  4. ncbi request reprint Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice
    Mark Zervas
    Skirball Institute, New York University School of Medicine, New York, USA
    J Neurosci Res 82:83-92. 2005
  5. ncbi request reprint Electrophysiological evaluation of engrafted stem cell-derived neurons
    Thoralf Opitz
    Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn and Hertie Foundation, Bonn, Germany
    Nat Protoc 2:1603-13. 2007
  6. doi request reprint Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons
    Julia Ladewig
    Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Stem Cells 26:1705-12. 2008

Collaborators

  • Thomas Voigt
  • P K Stanton
  • Julia Ladewig
  • Mark Zervas
  • Ana Dolabela de Lima
  • Ludwig Aigner
  • Banu Meiners
  • Philipp Koch
  • Oliver Brüstle
  • Elmar Endl
  • Sebastien Couillard-Despres
  • Bruce Wainer
  • Winfried Edelmann
  • Raju Kucherlapati

Detail Information

Publications6

  1. ncbi request reprint Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitro
    Thoralf Opitz
    Department of Developmental Physiology, Institute for Physiology, Otto von Guericke University, 39120 Magdeburg, Germany
    J Neurophysiol 88:2196-206. 2002
    ..However, in cultures older than 2 wk, inhibition of GABA(A) receptors does not result in block of synchronous network activity but in modulation of burst width and frequency...
  2. ncbi request reprint Activation of early silent synapses by spontaneous synchronous network activity limits the range of neocortical connections
    Thomas Voigt
    Department of Developmental Physiology, Otto von Guericke University, Institute of Physiology, 39120 Magdeburg, Germany
    J Neurosci 25:4605-15. 2005
    ..This activity-dependent process may set the range of corticocortical connections during early network development before experience-dependent mechanisms begin elaborating the mature layout of the neocortical connections and modules...
  3. ncbi request reprint Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity
    Ana Dolabela de Lima
    Otto von Guericke Universitat, Medizinische Fakultat, Institut fur Physiologie, 39120 Magdeburg, Germany
    Eur J Neurosci 19:2931-43. 2004
    ....
  4. ncbi request reprint Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice
    Mark Zervas
    Skirball Institute, New York University School of Medicine, New York, USA
    J Neurosci Res 82:83-92. 2005
    ....
  5. ncbi request reprint Electrophysiological evaluation of engrafted stem cell-derived neurons
    Thoralf Opitz
    Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn and Hertie Foundation, Bonn, Germany
    Nat Protoc 2:1603-13. 2007
    ..Here we provide protocols for the efficient electrophysiological evaluation of engrafted cells and highlight current limitations thereof...
  6. doi request reprint Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons
    Julia Ladewig
    Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Stem Cells 26:1705-12. 2008
    ..Combined with our lineage-selection procedure this cryopreservation technique enables the generation of human neurons in a ready-to-use format for a large variety of biomedical applications...