Affiliation: Otto-von-Guericke University
- Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitroThoralf Opitz
Department of Developmental Physiology, Institute for Physiology, Otto von Guericke University, 39120 Magdeburg, Germany
J Neurophysiol 88:2196-206. 2002..However, in cultures older than 2 wk, inhibition of GABA(A) receptors does not result in block of synchronous network activity but in modulation of burst width and frequency...
- Activation of early silent synapses by spontaneous synchronous network activity limits the range of neocortical connectionsThomas Voigt
Department of Developmental Physiology, Otto von Guericke University, Institute of Physiology, 39120 Magdeburg, Germany
J Neurosci 25:4605-15. 2005..This activity-dependent process may set the range of corticocortical connections during early network development before experience-dependent mechanisms begin elaborating the mature layout of the neocortical connections and modules...
- Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activityAna Dolabela de Lima
Otto von Guericke Universitat, Medizinische Fakultat, Institut fur Physiologie, 39120 Magdeburg, Germany
Eur J Neurosci 19:2931-43. 2004....
- Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient miceMark Zervas
Skirball Institute, New York University School of Medicine, New York, USA
J Neurosci Res 82:83-92. 2005....
- Electrophysiological evaluation of engrafted stem cell-derived neuronsThoralf Opitz
Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn and Hertie Foundation, Bonn, Germany
Nat Protoc 2:1603-13. 2007..Here we provide protocols for the efficient electrophysiological evaluation of engrafted cells and highlight current limitations thereof...
- Lineage selection of functional and cryopreservable human embryonic stem cell-derived neuronsJulia Ladewig
Institute of Reconstructive Neurobiology, Life and Brain Center, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Stem Cells 26:1705-12. 2008..Combined with our lineage-selection procedure this cryopreservation technique enables the generation of human neurons in a ready-to-use format for a large variety of biomedical applications...