Peter Malfertheiner

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. pmc Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
    P Malfertheiner
    Otto von Guericke Universitat Magdeburg, Medizinische Fakultat, Zentrum fur Innere Medizin, Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Gut 56:772-81. 2007
  2. pmc Implications of growth factor alterations in the treatment of pancreatic cancer
    Mark Juhasz
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Mol Cancer 2:5. 2003
  3. pmc Psychometric validation of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in patients with reflux disease
    Károly R Kulich
    Clinical Science, AstraZeneca R and D Molndal, Sweden
    Health Qual Life Outcomes 1:62. 2003
  4. pmc Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians
    Juozas Kupcinskas
    Department of Gastroenterology, Lithuanian University of Health Sciences, Eiveniu 2, 50009 Kaunas, Lithuania
    BMC Med Genet 12:112. 2011
  5. ncbi request reprint Helicobacter pylori eradication is beneficial in the treatment of functional dyspepsia
    P Malfertheiner
    Otto von Guericke Universitat, Zentrum fur Innere Medizin, Magdeburg, Germany
    Aliment Pharmacol Ther 18:615-25. 2003
  6. ncbi request reprint Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus Report
    P Malfertheiner
    Center for Internal Medicine, Clinic of Gastroenterology, Otto von Guericke University of Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Aliment Pharmacol Ther 16:167-80. 2002
  7. ncbi request reprint Clinical manifestations and complications of gastroesophageal reflux disease (GERD)
    P Malfertheiner
    Clinic for Gastroenterology, Otto von Guericke University Magdeburg, D 39210 Magdeburg, Germany
    Int J Clin Pract 59:346-55. 2005
  8. ncbi request reprint Is endoscopic ultrasonography superior to multidetector CT for assessing pancreatic cancer?
    Peter Malfertheiner
    Department of Gastroenterology, Hepatology and Infection, Otto von Guericke University in Magdeburg
    Nat Clin Pract Gastroenterol Hepatol 2:176-7. 2005
  9. ncbi request reprint [Guidelines for the diagnosis and treatment of H. pylori infection]
    P Malfertheiner
    Klinik fur Gastroenterologie, Zentrum fur Innere Medizin, Otto von Guericke Universitat Magdeburg
    MMW Fortschr Med 145:42-5. 2003
  10. ncbi request reprint Functional heartburn, nonerosive reflux disease, and reflux esophagitis are all distinct conditions--a debate: con
    Lucia C Fry
    Peter Malfertheiner, MD Department of Gastroenterology, Hepatology, and Infectious Diseases, Universitatsklinikum Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany
    Curr Treat Options Gastroenterol 10:305-11. 2007

Collaborators

Detail Information

Publications190 found, 100 shown here

  1. pmc Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
    P Malfertheiner
    Otto von Guericke Universitat Magdeburg, Medizinische Fakultat, Zentrum fur Innere Medizin, Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Gut 56:772-81. 2007
    ..Guidelines on the management of Helicobacter pylori, which cover indications for management and treatment strategies, were produced in 2000...
  2. pmc Implications of growth factor alterations in the treatment of pancreatic cancer
    Mark Juhasz
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Mol Cancer 2:5. 2003
    ..The molecular knowledge regarding changes in the expression of growth factors in pancreatic cancer has the potential to improve diagnostic and therapeutic treatment strategies in the near future...
  3. pmc Psychometric validation of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in patients with reflux disease
    Károly R Kulich
    Clinical Science, AstraZeneca R and D Molndal, Sweden
    Health Qual Life Outcomes 1:62. 2003
    ..The aim is to document the psychometric characteristics of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire...
  4. pmc Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians
    Juozas Kupcinskas
    Department of Gastroenterology, Lithuanian University of Health Sciences, Eiveniu 2, 50009 Kaunas, Lithuania
    BMC Med Genet 12:112. 2011
    ....
  5. ncbi request reprint Helicobacter pylori eradication is beneficial in the treatment of functional dyspepsia
    P Malfertheiner
    Otto von Guericke Universitat, Zentrum fur Innere Medizin, Magdeburg, Germany
    Aliment Pharmacol Ther 18:615-25. 2003
    ..To assess whether the eradication of Helicobacter pylori leads to long-term relief of symptoms in functional dyspepsia...
  6. ncbi request reprint Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus Report
    P Malfertheiner
    Center for Internal Medicine, Clinic of Gastroenterology, Otto von Guericke University of Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Aliment Pharmacol Ther 16:167-80. 2002
    ..Successful eradication should always be confirmed by urea breath test or an endoscopy-based test if endoscopy is clinically indicated. Stool antigen test is the alternative if urea breath test is not available...
  7. ncbi request reprint Clinical manifestations and complications of gastroesophageal reflux disease (GERD)
    P Malfertheiner
    Clinic for Gastroenterology, Otto von Guericke University Magdeburg, D 39210 Magdeburg, Germany
    Int J Clin Pract 59:346-55. 2005
    ..This paper addresses the symptoms, diseases and complications in which the abnormal reflux of gastric content to the oesophagus and adjacent organ systems is believed to be a frequent contributory factor...
  8. ncbi request reprint Is endoscopic ultrasonography superior to multidetector CT for assessing pancreatic cancer?
    Peter Malfertheiner
    Department of Gastroenterology, Hepatology and Infection, Otto von Guericke University in Magdeburg
    Nat Clin Pract Gastroenterol Hepatol 2:176-7. 2005
  9. ncbi request reprint [Guidelines for the diagnosis and treatment of H. pylori infection]
    P Malfertheiner
    Klinik fur Gastroenterologie, Zentrum fur Innere Medizin, Otto von Guericke Universitat Magdeburg
    MMW Fortschr Med 145:42-5. 2003
    ..pylori infection put out by the European Helicobacter Pylori Study Group (EHPSG) in Maastricht take account of the present state of our knowledge of the significance of H. pylori eradication...
  10. ncbi request reprint Functional heartburn, nonerosive reflux disease, and reflux esophagitis are all distinct conditions--a debate: con
    Lucia C Fry
    Peter Malfertheiner, MD Department of Gastroenterology, Hepatology, and Infectious Diseases, Universitatsklinikum Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany
    Curr Treat Options Gastroenterol 10:305-11. 2007
    ..It is difficult to clearly delineate the spectrum of GERD based on the clinical, endoscopic, and pathophysiologic characteristics, but therapeutic trials and follow-up studies suggest that GERD is not composed of different conditions...
  11. ncbi request reprint Impact of Helicobacter pylori eradication on heartburn in patients with gastric or duodenal ulcer disease -- results from a randomized trial programme
    P Malfertheiner
    Universitätsklinik Otto von Guericke, Magdeburg, Germany
    Aliment Pharmacol Ther 16:1431-42. 2002
    ..Helicobacter pylori infection has been proposed as a protective factor against the development of gastro-oesophageal reflux disease...
  12. pmc Prognostic influence of Barrett's oesophagus and Helicobacter pylori infection on healing of erosive gastro-oesophageal reflux disease (GORD) and symptom resolution in non-erosive GORD: report from the ProGORD study
    P Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Gut 54:746-51. 2005
    ..We report on factors influencing endoscopic healing and symptom resolution during the acute treatment phase...
  13. pmc Helicobacter pylori eradication does not exacerbate gastro-oesophageal reflux disease
    P Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Gut 53:312-3. 2004
    ..The critical question is whether eradication of H pylori has a more beneficial, harmful, or simply no effect on the course of GORD...
  14. pmc The interplay between Helicobacter pylori, gastro-oesophageal reflux disease, and intestinal metaplasia
    P Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, 39120 Magdeburg, Germany
    Gut 54:i13-20. 2005
    ..Available data on this issue, including follow up of a small patient series, are presented, but more studies are required to shed light on this issue because they will help to identify those patients that need surveillance...
  15. ncbi request reprint Helicobacter pylori eradication and gastric ulcer healing--comparison of three pantoprazole-based triple therapies
    P Malfertheiner
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Aliment Pharmacol Ther 17:1125-35. 2003
    ..To study the efficacy of three pantoprazole-based triple therapy regimens for the eradication of Helicobacter pylori infection and gastric ulcer healing...
  16. ncbi request reprint [Treatment of H. pylori infection--always necessary--pro]
    P Malfertheiner
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Otto von guerike Universitätsklinikum Magdeburg
    Dtsch Med Wochenschr 129:41-2. 2004
  17. ncbi request reprint [Helicobacter pylori infection--an update for 2004]
    P Malfertheiner
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie der Otto von Guericke Universität Magdeburg
    Dtsch Med Wochenschr 129:1821-6. 2004
  18. ncbi request reprint Treatment of Helicobacter pylori
    K Wolle
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, 39120 Magdeburg, Germany
    Best Pract Res Clin Gastroenterol 21:315-24. 2007
    ..However, following therapy failure beyond a second treatment attempt requires antibiotic resistance testing. New drugs and adjuvant agents have been reported but their efficacy needs further evaluation...
  19. ncbi request reprint Helicobacter pylori eradication in functional dyspepsia: new evidence for symptomatic benefit
    P Malfertheiner
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guercke University of Magdeburg, Germany
    Eur J Gastroenterol Hepatol 13:S9-11. 2001
    ..This study provides support for the recommendations of Maastricht 2, which found that H. pylori eradication is an appropriate therapeutic option for functional dyspepsia...
  20. ncbi request reprint Review article: from gastrin to gastro-oesophageal reflux disease--a century of acid suppression
    P Malfertheiner
    Otto von Guericke University, Magdeburg, Germany
    Aliment Pharmacol Ther 23:683-90. 2006
    ..The major issue for the future resides within the epidemic of gastro-oesophageal reflux disease. How to diagnose, categorize and treat this condition and how to identify and prevent neoplasia, are the challenges of the new century...
  21. ncbi request reprint [Peptic ulcer disease. Clinical evaluation in 2006]
    P Malfertheiner
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Otto v Guericke Universität, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Internist (Berl) 47:588, 590-5. 2006
    ..Optimized inhibition of acid secretion with proton pump inhibitors has made it possible to both prevent and cure ulcers in the stomach and duodenum caused by NSAR agents...
  22. ncbi request reprint The Maastricht recommendations and their impact on general practice
    P Malfertheiner
    Clinic of Gastroenterology, Hepatology and Infectiology, University of Magdeburg, Germany
    Eur J Gastroenterol Hepatol 11:S63-7; discussion S73. 1999
    ..The evidence supporting the use of these therapies has been substantiated in large clinical trials that were recently completed...
  23. ncbi request reprint Review article: managing the dyspeptic patient--an interactive discussion
    P Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Magdeburg, Leipziger Strasse 44, Haus 39, 39120 Magdeburg, Germany
    Aliment Pharmacol Ther 15:14-9. 2001
    ..The third case demonstrated that it can be difficult to make a definitive diagnosis based on clinical symptoms, and that patients with endoscopy-negative reflux disease usually respond well to PPI therapy...
  24. ncbi request reprint The GU-MACH study: the effect of 1-week omeprazole triple therapy on Helicobacter pylori infection in patients with gastric ulcer
    P Malfertheiner
    Universitätsklinik Otto von Guericke, Magdeburg, Germany
    Aliment Pharmacol Ther 13:703-12. 1999
    ..To study the efficacy of omeprazole triple therapy in the eradication of Helicobacter pylori in patients with active gastric ulcer, and to assess healing and relapse of gastric ulcer...
  25. ncbi request reprint Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
    Sabine Krueger
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    J Pathol 207:32-42. 2005
    ..Although no correlation of cathepsin X expression and TNM stage was found, our study demonstrates that cathepsin X plays a role not only in the chronic inflammation of gastric mucosa but also in the tumourigenesis of gastric cancer...
  26. ncbi request reprint Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease
    Eike Hollenbach
    Institute of Experimental Internal Medicine, Department of Gastroenterology, Hepatology and Infectiology, Otto von Guericke University, Magdeburg D 39120, Germany
    J Biol Chem 280:14981-8. 2005
    ..Because bacterial products are suggested to be the key pathogenic agents triggering IBD, inhibition of the NOD/RICK pathway may serve as a novel target of future therapies in human IBD...
  27. doi request reprint Progression of specialized intestinal metaplasia at the cardia to macroscopically evident Barrett's esophagus: an entity of concern in the ProGERD study
    Andreas Leodolter
    Department of Gastroenterology, Hepatology and Infectious Diseases, Sana Klinikum Remscheid, Germany
    Scand J Gastroenterol 47:1429-35. 2012
    ..The authors aim was to evaluate prospectively the progression of SIM+ to macroscopically evident Barrett's esophagus (BE/SIM+), and to identify risk factors for this progression...
  28. doi request reprint Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, 39120 Magdeburg, Germany
    Hum Pathol 43:1745-54. 2012
    ....
  29. ncbi request reprint Helicobacter pylori-induced downregulation of the secretory leukocyte protease inhibitor (SLPI) in gastric epithelial cell lines and its functional relevance for H. pylori-mediated diseases
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Biol Chem 387:893-901. 2006
    ..pylori-infected subjects has a functional relevance for gastric mucosa and the H. pylori-induced decrease in SLPI is primarily regulated at the posttranslational level...
  30. doi request reprint Enteroscopy
    Klaus Monkemuller
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Best Pract Res Clin Gastroenterol 22:789-811. 2008
    ....
  31. ncbi request reprint TFF3 expression at the esophagogastric junction is increased in gastro-esophageal reflux disease (GERD)
    Ulrich Peitz
    Department of Gastroenterology, Hepatology, and Infectiology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Peptides 25:771-7. 2004
    ..pylori status or to tumor necrosis factor-alpha (TNF-alpha) expression. The expression of TFF3 at the cardia may represent an adaptation to GERD and precede the development of Barrett's esophagus...
  32. ncbi request reprint Secretory leukocyte protease inhibitor expression in various types of gastritis: a specific role of Helicobacter pylori infection
    Istvan Hritz
    Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Gastroenterol Hepatol 18:277-82. 2006
    ..The aim of the study was to investigate whether SLPI downregulation of gastric mucosa represents a specific phenomenon of H. pylori infection or is generally linked to gastric inflammation...
  33. ncbi request reprint Prevalence of H pylori associated "high risk gastritis" for development of gastric cancer in patients with normal endoscopic findings
    Andreas Leodolter
    Department of Gastroenterology and Hepatology, Otto von Guericke University, Leipziger Street 44, Magdeburg D 39120, Germany
    World J Gastroenterol 12:5509-12. 2006
    ..To investigate the prevalence of H pylori associated corpus-predominant gastritis (CPG) or pangastritis, severe atrophy, and intestinal metaplasia (IM) in patients without any significant abnormal findings during upper-GI endoscopy...
  34. ncbi request reprint Cathepsins K, L, B, X and W are differentially expressed in normal and chronically inflamed gastric mucosa
    Frank Buhling
    Institute of Immunology, Otto von Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Biol Chem 385:439-45. 2004
    ..Immunohistochemistry revealed specific expression of cathepsin X (macrophages), cathepsin K (parietal cells) and cathepsin W (lymphocytes), whereas cathepsins B and L were predominantly expressed in epithelial cells...
  35. ncbi request reprint Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastric carcinogenesis in Germany
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Leipziger Str 44, 39120 Magdeburg, Germany
    Anticancer Res 30:505-11. 2010
    ..Polymorphisms of interleukin-1 beta gene (IL1B-511C>T) are considered as risk factor for gastric carcinogenesis, but conflicting data have been reported recently...
  36. doi request reprint Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Histopathology 60:405-15. 2012
    ..Gastro-oesophageal reflux disease (GERD) is associated with impaired epithelial barrier function. This study was aimed at investigating the role of desmosomal proteins in relation to GERD...
  37. doi request reprint Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study
    Ulrich Peitz
    Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Magdeburg, Magdeburg, Germany
    J Gastroenterol Hepatol 26:82-9. 2011
    ..pylori) antibodies. The aim of the present study was to evaluate whether serum markers correlate with and predict gastric atrophy in gastroesophageal reflux disease (GERD) patients...
  38. ncbi request reprint Down-regulation of secretory leukocyte protease inhibitor expression in gastric mucosa is a general phenomenon in Helicobacter pylori-related gastroduodenal diseases
    Thomas Wex
    Clinic for Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 22:390-5. 2004
    ..Recently, a local down-regulation of antral SLPI expression in Helicobacter pylori (Hp)-infected healthy volunteers was demonstrated...
  39. ncbi request reprint Protective role of heat shock protein 27 in gastric mucosal injury
    Matthias P A Ebert
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    J Pathol 207:177-84. 2005
    ..This indicates that HSP27 expression is critical for mucosal protection in the stomach...
  40. doi request reprint Helicobacter pylori infection and short-term intake of low-dose aspirin have different effects on alpha-1 antitrypsin/alpha-1 peptidase inhibitor (alpha1-PI) levels in antral mucosa and peripheral blood
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Scand J Gastroenterol 43:1194-201. 2008
    ....
  41. pmc Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression
    Doerthe Kuester
    Department of Pathology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Neoplasia 9:236-45. 2007
    ..003). Thus, we consider DAPK inactivation by promoter hypermethylation as an early event in Barrett's carcinogenesis and suggest that a decreased protein expression of DAPK likely plays a role in the development and progression of BA...
  42. pmc Serological assessment of gastric mucosal atrophy in gastric cancer
    Jan Bornschein
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    BMC Gastroenterol 12:10. 2012
    ..Aim of this study was to assess the performance of these serological tests in the presence of gastric neoplasia...
  43. doi request reprint Naturally occurring regulatory T cells (CD4+, CD25high, FOXP3+) in the antrum and cardia are associated with higher H. pylori colonization and increased gene expression of TGF-beta1
    Arne Kandulski
    Department of Gastroenterology, Hepatology and Infectious Diseases, Leipziger Str 44, D 39120, Germany
    Helicobacter 13:295-303. 2008
    ..FOXP3 was shown to be expressed in a subset of Treg cells known as 'naturally occurring Treg cells'. These cells have not been sufficiently studied in context to H. pylori-induced inflammation in human gastric mucosa...
  44. doi request reprint The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis
    Marino Venerito
    Department of Gastroenterology, Hepatology, Infectious Diseases, Otto von Guericke University Hospital, Leipziger Str 44, D 39120 Magdeburg, Germany
    Cancer Lett 270:218-28. 2008
    ..These results suggest an involvement of the COX-LOX pathway in gastric carcinogenesis...
  45. ncbi request reprint The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer
    Matthias P A Ebert
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Cancer Epidemiol Biomarkers Prev 14:2987-9. 2005
    ..Our study provides further evidence that the ACE insertion/deletion gene polymorphism may be linked to the development of early gastric cancer...
  46. doi request reprint Detection of neuroendocrine tumors of the small bowel by double balloon enteroscopy
    Michael Bellutti
    Department of Gastroenterology, Hepatology and Infectious Diseases, Universitatsklinikum, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Dig Dis Sci 54:1050-8. 2009
    ..The objective of this study was to evaluate the use of double balloon enteroscopy (DBE) for the detection of the primary tumor in patients with NET...
  47. ncbi request reprint Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis
    Irina Kouznetsova
    Institut für Molekularbiologie und Medizinische Chemie, Universitatsklinikum, Otto von Guericke Universitat Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Cell Tissue Res 328:365-74. 2007
    ..This indicates the special requirement, particularly of the esophagogastric junction, for TFF3-triggered protection and repair...
  48. doi request reprint Proteinase-activated receptor-2 in the pathogenesis of gastroesophageal reflux disease
    Arne Kandulski
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Am J Gastroenterol 105:1934-43. 2010
    ..This study aimed to evaluate the expression of PAR-2 in human esophageal mucosa of patients with gastroesophageal reflux disease (GERD) in relation to mucosal alterations...
  49. doi request reprint Gastroesophageal reflux disease does not lead to changes in the secretory leukocyte protease inhibitor expression in esophageal mucosa
    Thomas Wex
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Eur J Gastroenterol Hepatol 21:150-8. 2009
    ..Here, it was investigated whether the presence of GERD was associated with changes of mucosal SLPI expression...
  50. ncbi request reprint Loss of beta-catenin expression in metastatic gastric cancer
    Matthias P A Ebert
    Otto von Guericke University, Department of Gastroenterology, Hepatology, and Infectious Diseases, Leipzigerstr 44, D 39120 Magdeburg, Germany
    J Clin Oncol 21:1708-14. 2003
    ..Beta-catenin (beta-catenin) participates in intercellular adhesion and is an integral part of the Wnt signaling pathway. The role of beta-catenin in the pathogenesis of gastric cancer and its metastasis is largely unknown...
  51. doi request reprint Short-term/low-dose aspirin-induced duodenal erosions are not dependent on Helicobacter pylori infection, cyclooxygenase expression and prostaglandin E2 levels
    Marino Venerito
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Scand J Gastroenterol 43:801-9. 2008
    ..The aim of this study was to investigate the effects of low-dose aspirin on the induction of duodenal erosions, the expression of cyclooxygenases and prostaglandin (PG)-E(2) levels in healthy subjects according to their H. pylori status...
  52. pmc Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma
    Antal Csepregi
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, 39120 Magdeburg, Germany
    BMC Cancer 10:317. 2010
    ..Herein, we evaluated CDKN2A promoter methylation and p16 protein expression for the differentiation of hepatocellular carcinoma (HCC) from other liver tumors...
  53. doi request reprint [Fulminant duodenal bleeding as first manifestation of a neuroendocrine carcinoma of the pancreatic head]
    Kerstin Schütte
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Otto von Guericke Universitat Magdeburg, Magdeburg, Germany
    Med Klin (Munich) 105:291-5. 2010
    ..Afterwards, the systemic therapy was changed to a palliative chemotherapy with streptozotocin and 5-fluorouracil due to local progression of the disease and a Ki-67 index of 4% in the primary tumor...
  54. pmc APC promoter methylation and protein expression in hepatocellular carcinoma
    Antal Csepregi
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    J Cancer Res Clin Oncol 134:579-89. 2008
    ..We investigated the impact of promoter methylation on APC protein expression in patients with hepatocellular carcinoma (HCC)...
  55. ncbi request reprint Reflux esophagitis or Helicobacter infection? - diagnostic value of the inflammatory pattern in metaplastic mucosa at the squamocolumnar junction
    Thomas Guenther
    Department of Pathology, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Pathol Res Pract 203:831-7. 2007
    ..reflux-caused metaplasia...
  56. pmc Role of tight junction proteins in gastroesophageal reflux disease
    Klaus Monkemuller
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Magdeburg, Germany
    BMC Gastroenterol 12:128. 2012
    ..The aim of the study was to investigate the expression pattern of selected components involved in the formation of tight junctions in relation to GERD...
  57. ncbi request reprint Upregulation of cathepsin W-expressing T cells is specific for autoimmune atrophic gastritis compared to other types of chronic gastritis
    Doerthe Kuester
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Leipziger Str 44, Magdeburg 39120, Germany
    World J Gastroenterol 11:5951-7. 2005
    ..To investigate a pathophysiological role of cathepsin W (CatW), a putative thiol-dependent cysteine protease, which is specifically expressed in cytotoxic lymphocytes, in different types of chronic inflammation of the gastric mucosa...
  58. ncbi request reprint Gastroesophageal reflux disease leads to major alterations in lectin-binding in the columnar epithelium of the gastroesophageal junction
    Helmut Neumann
    Otto von Guericke University Magdeburg, Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany
    Scand J Gastroenterol 42:791-8. 2007
    ..The aim was to investigate the binding patterns of lectins UEA-I, DBA, HPA and PNA at the squamocolumnar junction in relation to the existence of gastroesophageal reflux disease (GERD) and Helicobacter pylori (H. pylori) infection...
  59. ncbi request reprint Helicobacter pylori infection, but not low-dose aspirin, results in a local reduction of the secretory leukocyte protease inhibitor in gastroduodenal mucosa
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Tongji Medical College of Basic Medical Sciences, Huazhong University of Wuhan, China
    Helicobacter 11:31-8. 2006
    ..Therefore, the effect of low-dose aspirin on gastrointestinal SLPI expression was analyzed in the context of H. pylori infection...
  60. ncbi request reprint Small-bowel metaplasia arising in the remnant esophagus after esophagojejunostomy--a [corrected] prospective study in patients with a history of total gastrectomy
    Ulrich Peitz
    Clinic of Gastroenterology, Hepatology, and Infectiology, Otto von Guericke University, Magdeburg, Germany
    Am J Gastroenterol 100:2062-70. 2005
    ..The aim of this study was to detect esophageal columnar metaplasia after total gastrectomy with esophagojejunostomy, a condition of enteric, but nonacidic reflux...
  61. ncbi request reprint Cardia-type metaplasia arising in the remnant esophagus after cardia resection
    Ulrich Peitz
    Department of Gastroenterology, Hepatology and Infectiology, Otto von Guericke University, Magdeburg, Germany
    Gastrointest Endosc 59:810-7. 2004
    ..The aim of this study was to investigate the mucosal effects of esophagogastrostomy, an artificial interface between esophageal squamous and gastric oxyntic epithelium...
  62. ncbi request reprint The tyrosine kinase inhibitor imatinib fails to inhibit pancreatic cancer progression
    Jie Chen
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Leipzigerstr 44, D 39120 Magdeburg, Germany
    Cancer Lett 233:328-37. 2006
    ..Quality of life was similar in both groups. In this small series of pancreatic cancer patients, treatment with imatinib was not associated with a significant control of cancer progression...
  63. doi request reprint Peptic ulcer disease
    Peter Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Lancet 374:1449-61. 2009
    ..We discuss the role of these agents in the causes of ulcer disease and therapeutic and preventive strategies for drug-induced ulcers. The rare but increasingly problematic H pylori-negative NSAID-negative ulcer is also examined...
  64. doi request reprint Lectin UEA-I-binding proteins are specifically increased in the squamous epithelium of patients with Barrett's esophagus
    Helmut Neumann
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Digestion 78:201-7. 2008
    ..Lectins represent a group of specific carbohydrate binding proteins that can be used as sensitive tools for the analysis of glycosylation patterns...
  65. doi request reprint Gastrointestinal endoscopy in the elderly: current issues
    Klaus Monkemuller
    Department of Internal Medicine, Gastroenterology, Hepatology and Infectious Diseases, Marienhospital GmbH, Josef Albers Strasse 70, Bottrop, Germany
    Best Pract Res Clin Gastroenterol 23:821-7. 2009
    ..The aim of this article is to review the role of endoscopy in elderly patients, paying special emphasis on indications, special precautions and specific interventions...
  66. doi request reprint H. pylori infection is a key risk factor for proximal gastric cancer
    Jan Bornschein
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Dig Dis Sci 55:3124-31. 2010
    ..Despite evidence for the association of distal gastric cancer (GC) with the H. pylori infection, relevance of the infection for proximal GC is uncertain...
  67. doi request reprint Chronic mucosal inflammation of the gastric cardia in gastroesophageal reflux disease is not regulated by FOXP3-expressing T cells
    Arne Kandulski
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg 39120, Germany
    Dig Dis Sci 54:1940-6. 2009
    ..Regulatory T cells have been demonstrated for H. pylori-induced gastritis, whereas their role has not been studied in GERD...
  68. ncbi request reprint Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine
    Jie Chen
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg 39120, Germany
    Clin Exp Metastasis 21:389-97. 2004
    ..In conclusion, using global gene expression analysis together with inhibition of DNA methylation, we demonstrate that hypermethylation of the promoters of certain cancer-related genes may play a role in cancer metastasis...
  69. ncbi request reprint The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene insertion/deletion polymorphism
    Christoph Rocken
    Department of Pathology, Institutes of Experimental Internal Medicine, Clinical Chemistry, and Biometrics, Otto von Guericke University, Magdeburg, Germany
    Clin Cancer Res 11:2526-30. 2005
    ..In the present study, we aimed to substantiate the putative significance of angiotensin I-converting enzyme (ACE) on gastric cancer biology by investigating the influence of its gene polymorphism on gastric cancer progression...
  70. ncbi request reprint Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach
    Hans Ulrich Schildhaus
    Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Int J Oncol 26:1493-500. 2005
    ..DAPK (0.54 on average) and FHIT methylation (0.77 on average) were also observed in NT samples. This might constitute an early epigenetic precursor lesion in the normally-appearing tissue surrounding the tumor...
  71. doi request reprint Chemoprevention of adenocarcinoma associated with Barrett's esophagus: potential options
    Helmut Neumann
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    Dig Dis 27:18-23. 2009
    ..Thus, attention should also be given to potential targets for prevention strategies that might arrest or delay the progression of BE to EAC. This article focuses on known and postulated targets for prevention of distal esophageal cancer...
  72. doi request reprint Dyspepsia and IBS symptoms in patients with NERD, ERD and Barrett's esophagus
    Helmut Neumann
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    Dig Dis 26:243-7. 2008
    ..Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are highly prevalent in the general population as does gastroesophageal reflux disease (GERD). Therefore, it is expected that these conditions may frequently overlap...
  73. ncbi request reprint Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues
    Wai K Leung
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Pathol 197:582-8. 2002
    ..Progressive loss of TFF1 and TFF2, together with the induction of TFF3, is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway...
  74. ncbi request reprint Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up
    C Knippig
    Dept Gastroenterology, Hepatology and Infectious Diseases, University Hospital of Magdeburg, Germany
    Z Gastroenterol 40:383-7. 2002
    ..pylori positive spouses. Therefore this study has been performed to evaluate the effect of the H. pylori status of family members on the reinfection rate of H. pylori positive patients after successful eradication therapy...
  75. ncbi request reprint Proteome analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasis-related proteins
    Jie Chen
    Department of Gastroenterology, Hepatology and Infectious Diseases, Research Center Immunology Institute of Experimental Internal Medicine, and Pathology, Otto von Guericke University, Magdeburg, Germany
    J Proteome Res 3:1009-16. 2004
    ..Combining well-defined animal models with proteome analysis will improve our understanding of the fundamental changes that contribute to the process of carcinogenesis and the formation of metastases in gastric cancer...
  76. doi request reprint The combined presence of H pylori infection and gastro-oesophageal reflux disease leads to an up-regulation of CDX2 gene expression in antrum and cardia
    J Bornschein
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    J Clin Pathol 62:254-9. 2009
    ..CDX2 is an epithelial transcription factor that regulates intestinal differentiation and is involved in the development of intestinal metaplasia (IM)...
  77. ncbi request reprint [Helicobacter pylori infection--current status in clinical practice and prospects]
    P Malfertheiner
    Otto von Guericke Universitat, Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Magdeburg
    Z Gastroenterol 40:15-9. 2002
  78. ncbi request reprint Influence of anti-Helicobacter triple-therapy with metronidazole, omeprazole and clarithromycin on intestinal microflora
    A Bühling
    State Institute of Hygiene Saxony Anhalt, Magdeburg, Germany
    Aliment Pharmacol Ther 15:1445-52. 2001
    ..Proton pump inhibitor-based therapy including two antibiotics is the treatment of choice for Helicobacter pylori infection. Oral antibiotic treatment can lead to intestinal overgrowth of potentially pathogenic bacteria...
  79. doi request reprint Double-balloon enteroscopy-assisted virtual chromoendoscopy for small-bowel disorders: a case series
    H Neumann
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Endoscopy 41:468-71. 2009
    ..Its use for the characterization of celiac and Crohn's disease appears to be limited. Overall, FICE may become a useful method that aids in characterization and provides new insights to small-bowel pathologies...
  80. doi request reprint Helicobacter pylori infection: a clinical overview
    A Kandulski
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Dig Liver Dis 40:619-26. 2008
    ....
  81. ncbi request reprint Validity of a Helicobacter pylori stool antigen assay for the assessment of H. pylori status following eradication therapy
    A Leodolter
    Department of Gastroenterology, Hepatology and Infectious Diseases, University of Magdeburg, Germany
    Eur J Gastroenterol Hepatol 13:673-6. 2001
    ..11 optical density, giving a sensitivity of 93.3% and a specificity of 93.9%. CONCLUSION: The HpSA test is a valid test for the assessment of H. pylori status after eradication therapy, provided an adjusted cut-off value is applied...
  82. ncbi request reprint Effects of low-dose aspirin on gastric erosions, cyclooxygenase expression and mucosal prostaglandin-E2 do not depend on Helicobacter pylori infection
    M Venerito
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Aliment Pharmacol Ther 23:1225-33. 2006
    ..The mechanisms by which Helicobacter pylori and low-dose aspirin induce gastric damage are not completely elucidated...
  83. ncbi request reprint [Healing peptic ulcer disease with therapy of Helicobacter pylori infection--an overview]
    A Leodolter
    , Hepatologie und Infektiologie, , Leipziger Strasse 44, D-39120 Magdeburg, Deutschland
    Wien Med Wochenschr 151:300-8. 2001
    ..Main topics of this overview are the principles and the therapeutic proceeding in the management of Helicobacter pylori-associated peptic ulcer disease. The differences between duodenal and gastric ulcer are especially dealt with...
  84. doi request reprint [Dilemma between gastroprotection and cardiovascular prevention]
    M Venerito
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Otto von Guericke Universitat, Magdeburg
    Dtsch Med Wochenschr 135:2193-8. 2010
    ..If both Clopidogrel and PPI need to be prescribed, a split dosage regimen of PPI in the morning and clopidogrel in the evening can be recommended. The short half-life of both medications explains the rationale of this recommendation...
  85. ncbi request reprint Impact of furazolidone-based quadruple therapy for eradication of Helicobacter pylori after previous treatment failures
    G Treiber
    Department of Gastroenterology Hepatology, University Hospital, Magdeburg, Germany
    Helicobacter 7:225-31. 2002
    ..This study investigated whether a quadruple regimen containing furazolidone could be effective as a third-line (salvage) therapy...
  86. ncbi request reprint Acute pancreatitis after argon plasma coagulation of duodenal polyps in a patient with familial adenomatous polyposis
    J Weigt
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Endoscopy 39:E278. 2007
  87. ncbi request reprint The association between the interleukin-1 polymorphisms and gastric cancer risk depends on the family history of gastric carcinoma in the study population
    Teresa Starzynska
    Department of Gastroenterology, Pomeranian Medical Academy, Szczecin, Poland
    Am J Gastroenterol 101:248-54. 2006
    ..The association between interleukin-1 polymorphisms, H. pylori and increased gastric cancer risk remains controversial...
  88. ncbi request reprint Helicobacter pylori and nonmalignant diseases
    Ernst J Kuipers
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, 3000 CA Rotterdam, The Netherlands
    Helicobacter 9:29-34. 2004
    ..In patients using proton pump inhibitors for GERD, H. pylori eradication leads to a resolution of their corpus-predominant pangastritis, without impairing the efficacy of PPI therapy...
  89. doi request reprint Hepatocellular carcinoma and liver cirrhosis: assessment of the liver function after Yttrium-90 radioembolization with resin microspheres or after CT-guided high-dose-rate brachytherapy
    Ricarda Ruhl
    Klinik fur Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg AöR, Magdeburg, Germany
    Dig Dis 27:189-99. 2009
    ..To identify changes of liver function after single-fraction irradiation or yttrium-90 radioembolization ((90)Y-RE) of hepatocellular carcinoma associated with liver cirrhosis on the basis of laboratory data...
  90. ncbi request reprint Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer
    Matthias P A Ebert
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, D 39120 Magdeburg, Germany
    Carcinogenesis 23:87-91. 2002
    ....
  91. doi request reprint Molecular markers of pancreatic cancer: development and clinical relevance
    Lucia C Fry
    Division of Gastroenterology, Otto von Guericke University, Magdeburg, Germany
    Langenbecks Arch Surg 393:883-90. 2008
    ..Therefore, one of the major goals in clinical pancreatology is to find molecular markers, specific and sensitive enough to make an early and correct diagnosis of pancreatic cancer, before it has disseminated and become untreatable...
  92. ncbi request reprint [Early gastric cancer--diagnosis and therapy]
    S Kolfenbach
    Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Otto v Guericke Universität, Magdeburg
    Praxis (Bern 1994) 95:1037-41. 2006
    ..Endoscopic mucosal tumor resection (EMR) is a new minimal invasive procedure for local tumor resection with excellent outcome in a well selected subset of patients...
  93. ncbi request reprint A novel immunoassay based on monoclonal antibodies for the detection of Helicobacter pylori antigens in human stool
    K Agha-Amiri
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany
    Z Gastroenterol 39:555-60. 2001
    ..The differences between positive and negative results obtained with the FemtoLab H. pyloritrade mark are greater in comparison to the Premier Platinum HpSA EIAtrade mark and therefore this test system allows a better distinction...
  94. ncbi request reprint Current standards in the diagnosis of Helicobacter pylori infection
    A Leodolter
    Department of Gastroenterology, Hepatology and Infectiology, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 19:116-22. 2001
    ..Serological tests have a lower diagnostic accuracy and should only be used for screening of H. pylori infection or after careful local validation...
  95. doi request reprint Serum gastrin and pepsinogens do not correlate with the different grades of severity of gastro-oesophageal reflux disease: a matched case-control study
    K Monkemuller
    Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Magdeburg, Magdeburg, Germany
    Aliment Pharmacol Ther 28:491-6. 2008
    ..Gastrin and pepsinogens reflect the functional state of the gastric mucosa...
  96. ncbi request reprint A meta-analysis comparing eradication, healing and relapse rates in patients with Helicobacter pylori-associated gastric or duodenal ulcer
    A Leodolter
    Department of Gastroenterology, Hepatology and Infectious Diseases, University of Magdeburg, Magdeburg, Germany
    Aliment Pharmacol Ther 15:1949-58. 2001
    ..CONCLUSIONS: The eradication of H. pylori infection cures both gastric and duodenal ulcer, and the cure rates are similar. This suggests that H. pylori is the key factor in peptic ulcer disease independent of the ulcer site...
  97. ncbi request reprint Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer
    Tobias Götze
    Department of Medicine II, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, D 81675 Munich, Germany
    Cancer Lett 251:228-36. 2007
    ..28; 95% CI=0.11-0.71). Thus, gene polymorphisms of the RFC gene might contribute to an increased risk of developing distal gastric cancer...
  98. ncbi request reprint Has education about Helicobacter pylori infection been effective? Worldwide survey of primary care physicians
    Jiaqing Huang
    Department of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    J Gastroenterol Hepatol 18:512-20. 2003
    ..Confusion exists among physicians about the management of Helicobacter pylori (H. pylori) infection. We aimed to survey primary care physicians' (PCP) knowledge and management of H. pylori-related diseases...
  99. pmc Frequent loss of TIMP-3 expression in progression of esophageal and gastric adenocarcinomas
    Ping Gu
    Department of Medicine II, Klinikum rechts der Isar, Technical University, Munich, Germany
    Neoplasia 10:563-72. 2008
    ..04). In summary, we observed frequent TIMP-3 promoter methylation in adenocarcinomas of the esophagus and stomach and the loss of TIMP-3 expression seems to be of clinical and prognostic relevance in these cancers...
  100. doi request reprint Markers for predicting severity and progression of acute pancreatitis
    Kerstin Schütte
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Leipziger Str 44, 39120 Magdeburg, Germany
    Best Pract Res Clin Gastroenterol 22:75-90. 2008
    ..Indication, timing and consequences of the methods applied need to be carefully considered and incorporated into clinical assessments to avoid costs and harm to the patient...
  101. doi request reprint Therapeutic ERCP with the double-balloon enteroscope in patients with Roux-en-Y anastomosis
    Klaus Monkemuller
    Division of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Universitatsklinikum Magdeburg, Magdeburg, Germany
    Gastrointest Endosc 67:992-6. 2008