T Kalinski

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. ncbi request reprint Digital workflow management for quality assessment in pathology
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 204:17-21. 2008
  2. doi request reprint Heterogeneity of angiogenesis and blood vessel maturation in cartilage tumors
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:339-45. 2009
  3. doi request reprint Lossy compression in diagnostic virtual 3-dimensional microscopy--where is the limit?
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Hum Pathol 40:998-1005. 2009
  4. doi request reprint Improvements in education in pathology: virtual 3D specimens
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:811-4. 2009
  5. ncbi request reprint Hepatocellular carcinoma: pathology and liver biopsy
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 27:102-8. 2009
  6. doi request reprint Down-regulation of ephrin-A5, a gene product of normal cartilage, in chondrosarcoma
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Hum Pathol 40:1679-85. 2009
  7. doi request reprint [Angiogenesis in cartilage tumors]
    T Kalinski
    Institut fur Pathologie, Otto von Guericke Universitat, Leipziger Str 44, 39120 Magdeburg
    Pathologe 31:177-82. 2010
  8. ncbi request reprint ADAMTS1 is regulated by interleukin-1beta, not by hypoxia, in chondrosarcoma
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Hum Pathol 38:86-94. 2007
  9. doi request reprint Virtual 3D microscopy using multiplane whole slide images in diagnostic pathology
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Am J Clin Pathol 130:259-64. 2008
  10. doi request reprint [Rare neuroendocrine carcinoma of the gall bladder. Coincidental occurrence of an endometrioid ovarian adenocarcinoma]
    M Petersen
    Klinik fUr Allgemein, Viszeral und Gefässchirurgie, Universitatsklinikum, Magdeburg, Germany
    Dtsch Med Wochenschr 134:19-22. 2009

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Digital workflow management for quality assessment in pathology
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 204:17-21. 2008
    ..Moreover, digital workflow management provides the basis for the integration of diagnostic virtual microscopy...
  2. doi request reprint Heterogeneity of angiogenesis and blood vessel maturation in cartilage tumors
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:339-45. 2009
    ..Altogether, cartilage tumors exhibit a heterogeneous but predominantly mature angiogenic phenotype with differential proliferative activity...
  3. doi request reprint Lossy compression in diagnostic virtual 3-dimensional microscopy--where is the limit?
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Hum Pathol 40:998-1005. 2009
    ..We conclude that compression ratios higher than those commonly used can be applied in virtual microscopy, even in diagnostic applications...
  4. doi request reprint Improvements in education in pathology: virtual 3D specimens
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 205:811-4. 2009
    ..Virtual 3D specimens expand the application of digital techniques in pathology, and will contribute significantly to the successful introduction of knowledge databases and electronic learning platforms...
  5. ncbi request reprint Hepatocellular carcinoma: pathology and liver biopsy
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 27:102-8. 2009
    ..We further specify problems and pitfalls in the differential diagnosis and discuss limitations of liver biopsies in the diagnosis of HCC...
  6. doi request reprint Down-regulation of ephrin-A5, a gene product of normal cartilage, in chondrosarcoma
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Hum Pathol 40:1679-85. 2009
    ....
  7. doi request reprint [Angiogenesis in cartilage tumors]
    T Kalinski
    Institut fur Pathologie, Otto von Guericke Universitat, Leipziger Str 44, 39120 Magdeburg
    Pathologe 31:177-82. 2010
    ..Furthermore, we describe the effects of hypoxia and interleukin-1β on angiogenic signaling in chondrosarcoma cells...
  8. ncbi request reprint ADAMTS1 is regulated by interleukin-1beta, not by hypoxia, in chondrosarcoma
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Hum Pathol 38:86-94. 2007
    ..We believe that IL-1beta has a stronger impact on vascularization in chondrosarcomas than hypoxia, as both factors, ADAMTS1 and VEGF-A, are regulated in a way that favors angiogenesis...
  9. doi request reprint Virtual 3D microscopy using multiplane whole slide images in diagnostic pathology
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Am J Clin Pathol 130:259-64. 2008
    ..95 each, which was approximately the same as in conventional microscopy. We consider virtual 3D microscopy appropriate for primary diagnosis of H pylori gastritis and equivalent to conventional microscopy...
  10. doi request reprint [Rare neuroendocrine carcinoma of the gall bladder. Coincidental occurrence of an endometrioid ovarian adenocarcinoma]
    M Petersen
    Klinik fUr Allgemein, Viszeral und Gefässchirurgie, Universitatsklinikum, Magdeburg, Germany
    Dtsch Med Wochenschr 134:19-22. 2009
    ..The histological investigation of a surgical specimen (after cholecystectomy) from a 73-year-old woman revealed a poorly differentiated carcinoma with glandular structures and a lymph node metastasis...
  11. doi request reprint Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells
    Atanas Ignatov
    Department of Obstetrics and Gynecology, Otto von Guericke University, G Hauptmann Str 35, 39108 Magdeburg, Germany
    Breast Cancer Res Treat 123:87-96. 2010
    ..This data suggests the important role of GPR30/EGFR receptor signaling in the development of tamoxifen resistance. The inhibition of this pathway is a valid option to improve anti-hormone response in breast cancer...
  12. doi request reprint Self-renewal of the human gastric epithelium: new insights from expression profiling using laser microdissection
    Irina Kouznetsova
    Institute of Molecular Biology and Medicinal Chemistry, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Mol Biosyst 7:1105-12. 2011
    ....
  13. ncbi request reprint [Virtual microscopy and digital pathology]
    T Kalinski
    Institut fur Pathologie, Otto von Guericke Universitat Magdeburg, Germany
    Pathologe 27:222-7. 2006
    ..In the long term, digital archives and networks will be established that will allow for a worldwide access to virtual specimens...
  14. ncbi request reprint Establishment and characterization of the permanent human cell line C3842 derived from a secondary chondrosarcoma in Ollier's disease
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Virchows Arch 446:287-99. 2005
    ..In conclusion, the cell line C3842 provides the first model of a secondary chondrosarcoma in Ollier's disease in vitro, which is characterized by distinct features of such malignant cartilage tumors...
  15. ncbi request reprint BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC
    T Ignatov
    Department of Obstetrics and Gynecology, Otto von Guericke University, G Hauptmann Str 35, 39108, Magdeburg, Germany
    Breast Cancer Res Treat 141:205-12. 2013
    ..BRCA1 promoter methylation is a common mechanism of BRCA1 gene aberration in sporadic breast cancer and is predictive for better response to anthracycline-based therapies...
  16. ncbi request reprint Digital imaging and electronic patient records in pathology using an integrated department information system with PACS
    Thomas Kalinski
    Institute of Pathology, Otto von Guericke University, Magdeburg, Germany
    Pathol Res Pract 198:679-84. 2002
    ..Moreover, we evaluate the current situation and future prospects for PACS in pathology...
  17. ncbi request reprint Digital pathology: DICOM-conform draft, testbed, and first results
    Ralf Zwönitzer
    Department of Biometry and Medical Informatics, Otto von Guericke University, Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Comput Methods Programs Biomed 87:181-8. 2007
    ..The results showed that digital pathology is feasible but strong efforts by users and vendors are still necessary to integrate Digital Pathology into existing information systems...
  18. ncbi request reprint Helicobacter pylori alters the distribution of ZO-1 and p120ctn in primary human gastric epithelial cells
    Sabine Krueger
    Department of Pathology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Pathol Res Pract 203:433-44. 2007
    ..These alterations, triggered by H. pylori infection, are associated with an elongation phenotype and increased migration...
  19. ncbi request reprint Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
    Sabine Krueger
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    J Pathol 207:32-42. 2005
    ..Although no correlation of cathepsin X expression and TNM stage was found, our study demonstrates that cathepsin X plays a role not only in the chronic inflammation of gastric mucosa but also in the tumourigenesis of gastric cancer...
  20. ncbi request reprint Differential expression of VEGF-A and angiopoietins in cartilage tumors and regulation by interleukin-1beta
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Cancer 106:2028-38. 2006
    ..As interleukin (IL)-1beta has been found to be an indispensable factor in angiogenic signaling, we further analyzed the effect of IL-1beta on the expression of VEGF-A, Ang-1, and Ang-2 using a previously established cell culture model...
  21. ncbi request reprint Distribution of sex chromosomes in dysgenetic gonads of mixed type
    A Röpke
    Institute of Human Genetics, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Cytogenet Genome Res 116:146-51. 2007
    ..The proportion of XY/X cells in theca-like cells and Leydig cells was similar to that of the whole dysgenetic gonad. In contrast to these findings, spermatogonia exclusively contained an XY constellation...
  22. ncbi request reprint Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins
    Irina Kouznetsova
    IInstitut fur Molekularbiologie und Medizinische Chemie, Otto von Guericke Universitat Magdeburg, Magdeburg, Germany
    Cell Physiol Biochem 20:899-908. 2007
    ..This points to different physiological functions of TFF1 and TFF2, the latter maybe acting as a 'link peptide' for stabilization of the gastric mucus...
  23. ncbi request reprint Liver cirrhosis and membranoproliferative glomerulonephritis caused by inapparent hepatitis C virus infection
    Thomas Kalinski
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Pathol Res Pract 202:891-4. 2006
    ..Specimens of FFPE liver tissue may be used for the diagnosis of HCV infection, even if the tissue was obtained in a postmortem examination...
  24. ncbi request reprint Helicobacter pylori encoding the pathogenicity island activates matrix metalloproteinase 1 in gastric epithelial cells via JNK and ERK
    Sabine Krueger
    Institute of Pathology, Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany
    J Biol Chem 281:2868-75. 2006
    ..Induction of MMP-1 is further implicated in complex processes induced by H. pylori, resulting in tissue degradation and remodeling of the gastric mucosa...
  25. doi request reprint Human intestinal TFF3 forms disulfide-linked heteromers with the mucus-associated FCGBP protein and is released by hydrogen sulfide
    Timo K Albert
    Institute of Molecular Biology and Medicinal Chemistry, Otto von Guericke University Magdeburg, Magdeburg, Germany
    J Proteome Res 9:3108-17. 2010
    ..Also proteolytic processing of FCGBP was observed which is in line with multiple autocatalytic cleavages as proposed earlier by Johansson et al. (J. Proteome Res. 2009 , 8 , 3549 - 3557)...
  26. ncbi request reprint Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis
    Irina Kouznetsova
    Institut für Molekularbiologie und Medizinische Chemie, Universitatsklinikum, Otto von Guericke Universitat Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Cell Tissue Res 328:365-74. 2007
    ..This indicates the special requirement, particularly of the esophagogastric junction, for TFF3-triggered protection and repair...
  27. ncbi request reprint Interactions between human colon carcinoma cells, fibroblasts and monocytic cells in coculture--regulation of cathepsin B expression and invasiveness
    Sabine Krueger
    Department of Pathology, Otto von Guericke University Magdeburg, Leipziger Str 44, 39120 Magdeburg, Germany
    Cancer Lett 223:313-22. 2005
    ..This is dependent on the functional activity of cathepsin B as shown by specific siRNA's and seems to be regulated by activation of ERK1/2 and p38 signal transduction pathways...
  28. ncbi request reprint A randomized study of docetaxel and dexamethasone with low- or high-dose estramustine for patients with advanced hormone-refractory prostate cancer
    Thomas Nelius
    Department of Urology, Otto von Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    BJU Int 98:580-5. 2006
    ....