P Danos

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. ncbi Schizophrenia and anteroventral thalamic nucleus: selective decrease of parvalbumin-immunoreactive thalamocortical projection neurons
    P Danos
    Department of Psychiatry, University of Magdeburg, FRG
    Psychiatry Res 82:1-10. 1998
  2. ncbi Eeg alpha rhythm and glucose metabolic rate in the thalamus in schizophrenia
    P Danos
    Neuroscience PET Laboratory, Mount Sinai Medical Center, New York, NY, USA
    Neuropsychobiology 43:265-72. 2001
  3. ncbi Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: a stereological CT study
    P Danos
    Department of Psychiatry, University of Magdeburg, Germany
    Neuropsychobiology 38:80-3. 1998
  4. ncbi Volumes of association thalamic nuclei in schizophrenia: a postmortem study
    Peter Danos
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, 39120, Magdeburg, Germany
    Schizophr Res 60:141-55. 2003
  5. ncbi Increased number of nitric oxide synthase immunoreactive Purkinje cells and dentate nucleus neurons in schizophrenia
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    J Neurocytol 30:661-70. 2001
  6. ncbi Morphometric studies of the entorhinal cortex in neuropsychiatric patients and controls: clusters of heterotopically displaced lamina II neurons are not indicative of schizophrenia
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Germany
    Schizophr Res 33:125-32. 1998
  7. ncbi Low and infrequent expression of nitric oxide synthase/NADPH-diaphorase in neurons of the human supraoptic nucleus: a histochemical study
    H G Bernstein
    Department of Psychiatry, Otto v Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    J Chem Neuroanat 20:177-83. 2000
  8. ncbi Fewer beta-endorphin expressing arcuate nucleus neurons and reduced beta-endorphinergic innervation of paraventricular neurons in schizophrenics and patients with depression
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Cell Mol Biol (Noisy-le-grand) 48:OL259-65. 2002
  9. ncbi Tyrosine hydroxylase immunoreactivity in the locus coeruleus is reduced in depressed non-suicidal patients but normal in depressed suicide patients
    B Baumann
    Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 249:212-9. 1999
  10. ncbi Circumscribed numerical deficit of dorsal raphe neurons in mood disorders
    B Baumann
    Department of Psychiatry, University, of Magdeburg, Germany
    Psychol Med 32:93-103. 2002

Detail Information

Publications19

  1. ncbi Schizophrenia and anteroventral thalamic nucleus: selective decrease of parvalbumin-immunoreactive thalamocortical projection neurons
    P Danos
    Department of Psychiatry, University of Magdeburg, FRG
    Psychiatry Res 82:1-10. 1998
    ..The reductions of parvalbumin-positive thalamocortical projection neurons were not correlated with the length of disease, this finding supporting the neurodevelopmental etiology of structural abnormalities in schizophrenia...
  2. ncbi Eeg alpha rhythm and glucose metabolic rate in the thalamus in schizophrenia
    P Danos
    Neuroscience PET Laboratory, Mount Sinai Medical Center, New York, NY, USA
    Neuropsychobiology 43:265-72. 2001
    ..Furthermore, the present results suggest differences in thalamocortical circuits between normal controls and schizophrenic subjects...
  3. ncbi Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: a stereological CT study
    P Danos
    Department of Psychiatry, University of Magdeburg, Germany
    Neuropsychobiology 38:80-3. 1998
    ..The present results suggest that opiate dependence is associated with structural brain alterations. However, the relationship between opiate dependence and structural brain changes is complex and still not well understood...
  4. ncbi Volumes of association thalamic nuclei in schizophrenia: a postmortem study
    Peter Danos
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, 39120, Magdeburg, Germany
    Schizophr Res 60:141-55. 2003
    ..However, the findings of a substantial volume reduction of the THAL suggest that the volumes of additional thalamic nuclei may be also reduced in schizophrenia...
  5. ncbi Increased number of nitric oxide synthase immunoreactive Purkinje cells and dentate nucleus neurons in schizophrenia
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    J Neurocytol 30:661-70. 2001
    ..Our failure to show an altered expression of two calcium sensor proteins possibly points to a less important role of calcium signaling in cerebellar pathology of the disease...
  6. ncbi Morphometric studies of the entorhinal cortex in neuropsychiatric patients and controls: clusters of heterotopically displaced lamina II neurons are not indicative of schizophrenia
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Germany
    Schizophr Res 33:125-32. 1998
    ..Our data show that heterotopias are common to the rostral part of the human entorhinal cortex and are not a suitable neuroanatomical marker of schizophrenia...
  7. ncbi Low and infrequent expression of nitric oxide synthase/NADPH-diaphorase in neurons of the human supraoptic nucleus: a histochemical study
    H G Bernstein
    Department of Psychiatry, Otto v Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    J Chem Neuroanat 20:177-83. 2000
    ..No correlation was found between the expression of the enzyme in supraoptic neurons and the psychiatric status of the patients...
  8. ncbi Fewer beta-endorphin expressing arcuate nucleus neurons and reduced beta-endorphinergic innervation of paraventricular neurons in schizophrenics and patients with depression
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Cell Mol Biol (Noisy-le-grand) 48:OL259-65. 2002
    ..Our results showing an altered endorphinergic system in human hypothalami of schizophrenics and depressives might contribute to a renewal of interest in this peptide as a possible factor of importance in psychiatric disorders...
  9. ncbi Tyrosine hydroxylase immunoreactivity in the locus coeruleus is reduced in depressed non-suicidal patients but normal in depressed suicide patients
    B Baumann
    Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 249:212-9. 1999
    ..Indirect evidence is provided that suicide is not related to decreased noradrenergic function and that traditional antidepressants may enhance noradrenergic activity of the LC in depressed patients...
  10. ncbi Circumscribed numerical deficit of dorsal raphe neurons in mood disorders
    B Baumann
    Department of Psychiatry, University, of Magdeburg, Germany
    Psychol Med 32:93-103. 2002
    ..This structural deviation may contribute to impaired serotonergic innervation of brain regions which are involved in the pathology of mood disorders...
  11. ncbi Decreased density of GABA-A receptors in the left sensorimotor cortex in akinetic catatonia: investigation of in vivo benzodiazepine receptor binding
    G Northoff
    Department of Psychiatry, Otto von Guericke University of Magdeburg, Germany
    J Neurol Neurosurg Psychiatry 67:445-50. 1999
    ..The benzodiazepine receptor distribution was therefore investigated in akinetic catatonia with single photon emission tomography (SPECT) using iodine-123-iomazenil ((123) I Iomazenil)...
  12. ncbi Pathological regional cerebral blood flow in opiate-dependent patients during withdrawal: a HMPAO-SPECT study
    P Danos
    Department of Psychiatry, University of Magdeburg, Germany
    Neuropsychobiology 37:194-9. 1998
    ..The present results suggest brain perfusion abnormalities during heroin withdrawal in heroin-dependent patients, which are not due to the conditions of withdrawal...
  13. ncbi Further immunohistochemical evidence for impaired NO signaling in the hypothalamus of depressed patients
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, D 39120 Magdeburg, Germany
    Ann N Y Acad Sci 973:91-3. 2002
    ..The number of NOS-immunoreactive SCN neurons was significantly reduced in depression. We conclude that affective disorders are accompanied by impaired hypothalamic NO signaling...
  14. ncbi Impairment in visual-spatial function in catatonia: a neuropsychological investigation
    G Northoff
    Department of Psychiatry, Otto von Guericke University of Magdeburg, Germany
    Schizophr Res 37:133-47. 1999
    ..The data suggest attentional-motor and fronto-parietal dysfunction in catatonia, a conclusion which should be considered as preliminary, however, due to the small sample size...
  15. ncbi Delayed onset of late movement-related cortical potentials and abnormal response to lorazepam in catatonia
    G Northoff
    Department of Psychiatry of Otto von Guericke, University Magdeburg, Leipziger Strasse 44, 39120, Magdeburg, Germany
    Schizophr Res 44:193-211. 2000
    ..Differential and stronger response to lorazepam in catatonia suggests dysfunction in inhibitory control of cortical motor function with increased gaba-ergic sensitivity...
  16. ncbi Regional and cellular distribution of neural visinin-like protein immunoreactivities (VILIP-1 and VILIP-3) in human brain
    H G Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    J Neurocytol 28:655-62. 1999
    ..Glia did not express visinin-like proteins. Our findings support, from a neuroanatomical viewpoint, the idea that these calcium sensor proteins may be of relevance for neuronal signalling in the human CNS...
  17. ncbi Disposition of haloperidol pyridinium and reduced haloperidol pyridinium in schizophrenic patients: no relationship with clinical variables during short-term treatment
    S Ulrich
    Institute of Clinical Pharmacology, University Hospital, Otto von Guericke University, Magdeburg, Germany
    J Clin Psychopharmacol 20:210-9. 2000
    ..Finally, it is concluded that the serum concentration of the parent drug remains the main variable of interest in the therapeutic drug monitoring of haloperidol during short-term treatment...
  18. ncbi Can chronic neuroleptic treatment promote sleep disturbances in elderly schizophrenic patients?
    J Staedt
    Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
    Int J Geriatr Psychiatry 15:170-6. 2000
    ..Potential pathophysiological relationships between long-term neuroleptic therapy and NMS occurrence are discussed. Our findings suggest that long-term administration of neuroleptics favours the appearance of insomnia...
  19. ncbi [Pathology of the thalamus and schizophrenia--an overview]
    P Danos
    Klinik fur Psychiatrie, Psychosomatische Medizin und Psychotherapie der Universitätsklinik Magdeburg
    Fortschr Neurol Psychiatr 72:621-34. 2004
    ..The reviewed data suggest that distinct thalamic nuclei and therefore distinct neuronal circuits are involved in the pathogenesis of schizophrenia...