Stephan R Orth
- Smoking: a risk factor for progression of chronic kidney disease and for cardiovascular morbidity and mortality in renal patients--absence of evidence or evidence of absence?Stephan R Orth
Dialysis Center Bad Aibling, Bad Aibling, Germany
Clin J Am Soc Nephrol 3:226-36. 2008..The conclusion is that smoking is an important renal risk factor, and nephrologists have to invest more efforts to motivate patients to stop smoking...
- Effect of a selective endothelin receptor A blocker on cardiovascular remodeling in uninephrectomized spontaneously hypertensive rats of the stroke-prone strainStephan R Orth
Department of Internal Medicine II, University of Regensburg, Regensburg, Germany
Kidney Blood Press Res 30:400-7. 2007....
- Effects of smoking on systemic and intrarenal hemodynamics: influence on renal functionStephan R Orth
Dialysezentrum Schwandorf Klinikum für Innere Medizin II, University of Regensburg, Germany
J Am Soc Nephrol 15:S58-63. 2004..g., endothelial cell dysfunction). Renal failure per se leads to an increased cardiovascular risk. The latter is further aggravated by smoking. Particularly, survival of smokers with diabetes on hemodialysis is abysmal...
- Traditional and nontraditional cardiovascular risk factors and estimated risk for coronary artery disease in renal transplant recipients: a single-center experienceMiriam C Banas
Klinik und Poliklinik fur Innere Medizin II, Nephrologie, University of Regensburg, Regensburg, Germany
Nephron Clin Pract 119:c227-35. 2011....
- Smoking behaviour of patients before and after renal transplantationMiriam C Banas
Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, D 93042 Regensburg, Germany
Nephrol Dial Transplant 23:1442-6. 2008..To date, only limited information about changes in cigarette-smoking habits before and after renal transplantation is available...
- Effects of smoking on renal function in patients with type 1 and type 2 diabetes mellitusStephan R Orth
, University of Regensburg, Regensburg, Germany
Nephrol Dial Transplant 20:2414-9. 2005..The latter finding suggests a mechanism independent of glomerular damage...
- Blood pressure-independent effect of long-term treatment with the soluble heme-independent guanylyl cyclase activator HMR1766 on progression in a model of noninflammatory chronic renal damageKerstin Benz
Department of Pediatrics, University of Erlangen, Erlangen, Germany
Kidney Blood Press Res 30:224-33. 2007..6 +/- 9). The results document beneficial BP-independent HMR1766 effects on kidney structure and urinary albumin excretion in a noninflammatory model of renal failure and may argue for a novel therapeutic principle...
- Beneficial effects of calcimimetics on progression of renal failure and cardiovascular risk factorsHiroaki Ogata
Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany
J Am Soc Nephrol 14:959-67. 2003..Furthermore, it interferes with the development of cardiovascular risk factors and cardiac remodeling...
- Combination treatment with an ET(A)-receptor blocker and an ACE inhibitor is not superior to the respective monotherapies in attenuating chronic transplant vasculopathy in different aorta allotransplantation rat modelsStephan R Orth
Division of Nephrology and Hypertension, University Hospital Berne Inselspital, Berne, Switzerland
Nephrol Dial Transplant 18:62-9. 2003..Untreated sham-operated and isografted WKY and SHR served as controls. Allotransplanted animals treated with the angiotensin-converting enzyme (ACE) inhibitor trandolapril served as positive treatment controls...
- Monocyte chemoattractant protein-1 (MCP-1) in the kidney: does it more than simply attract monocytes?Christiane Viedt
Nephrol Dial Transplant 17:2043-7. 2002
- The renal risks of smoking: an updateStephan R Orth
Division of Nephrology and Hypertension, Inselspital, University of Berne, Berne, Switzerland
Curr Opin Nephrol Hypertens 11:483-8. 2002..For all the above reasons cessation of smoking should be recommended to renal patients - a recommendation which is infrequently given and even less frequently followed...
- Smoking and the kidneyStephan R Orth
Division of Nephrology and Hypertension, University Hospital Berne (Inselspital, Berne, Switzerland
J Am Soc Nephrol 13:1663-72. 2002
- Combination treatment with an ET(A)-receptor blocker and an ACE inhibitor is not superior to the respective monotherapies in attenuating chronic transplant nephropathy in a 'Fisher-to-Lewis' rat modelJudith Adams
Department of Urology, Ruperto Carola University, Heidelberg, Germany
Nephrol Dial Transplant 17:780-7. 2002..This finding is consistent with the notion that ET(A)-receptor mediated events play a partly BP-independent role in the genesis of CTN. Combination therapy exerts no additive nephroprotection...
- Smoking and dialysis: a dreadful scenario for the cardiovascular system?Stephan R Orth
Kidney Int 63:1580-1. 2003
- Adverse effect of smoking on renal function in the general population: are men at higher risk?Stephan R Orth
Am J Kidney Dis 40:864-6. 2002
- Cigarette smoke condensate aggravates renal injury in the renal ablation modelGiulio Odoni
Department of Internal Medicine, Ruperto Carola University, Heidelberg, Germany
Kidney Int 61:2090-8. 2002..Renal injury induced by cigarette smoke condensate in this model is reversed by renal denervation. We conclude that cigarette smoke-induced renal damage is due, at least in part, to activation of the sympathetic nerve system...