Research Topics
Genomes and GenesSpecies | Vinzenz OjiSummaryCountry: Germany Publications
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Detail Information
Publications
Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009Vinzenz Oji
Department of Dermatology, University Hospital Munster, Munster, Germany
J Am Acad Dermatol 63:607-41. 2010..Over the recent years, much progress has been made defining their molecular causes. However, there is no internationally accepted classification and terminology...
Ichthyosis vulgaris: novel FLG mutations in the German population and high presence of CD1a+ cells in the epidermis of the atopic subgroupV Oji
Department of Dermatology, University of Munster, Von Esmarch Str 58, 48149 Munster, Germany
Br J Dermatol 160:771-81. 2009..Ichthyosis vulgaris (IV) is a genetic disorder with a prevalence of 1:250-1000 caused by filaggrin (FLG) mutations, which also predispose to atopic diseases...
Plasminogen activator inhibitor-2 is expressed in different types of congenital ichthyosis: in vivo evidence for its cross-linking into the cornified cell envelope by transglutaminase-1V Oji
Department of Dermatology, University of Munster, Germany
Br J Dermatol 154:860-7. 2006..Protease inhibitors are essential for skin homeostasis and in particular for the regulation of the desquamation process. Therefore, an aberrant expression of PAI-2 could be involved in the pathogenesis of certain cornification disorders...
Ichthyoses: differential diagnosis and molecular geneticsVinzenz Oji
Department of Dermatology, University Hospital, Von Esmarch Str 58, 48149 Munster, Germany
Eur J Dermatol 16:349-59. 2006..The different pathomechanisms causing ichthyosis provide a fascinating insight into the role of various proteins, enzymes, lipids and metabolic pathways involved in terminal epidermal differentiation/keratinisation...
Ichthyosis: clinical manifestations and practical treatment optionsVinzenz Oji
Department of Dermatology, University of Munster, Munster, Germany
Am J Clin Dermatol 10:351-64. 2009..Patients with lamellar ichthyosis or ichthyosiform erythroderma in particular profit from oral therapy with retinoids or retinoic acid metabolism-blocking agents...
Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin diseaseVinzenz Oji
Department of Dermatology, University Hospital Munster, 48149 Munster, Germany
Am J Hum Genet 87:274-81. 2010..Therefore, peeling skin disease will represent a new model disorder for atopic diseases, similarly to Netherton syndrome and ichthyosis vulgaris in the recent past...
Bathing suit ichthyosis is caused by transglutaminase-1 deficiency: evidence for a temperature-sensitive phenotypeVinzenz Oji
Department of Dermatology, University of Muenster, Von Esmarch Str 58 D 48149, Munster, Germany
Hum Mol Genet 15:3083-97. 2006..We conclude that BSI is caused by TGase-1 deficiency and suggest that it is a temperature-sensitive phenotype...
Ichthyoses--Part 2: Congenital ichthyosesMarkus Krug
Department of Dermatology, University of Tubingen, Germany
J Dtsch Dermatol Ges 7:577-88. 2009..Patients with uncommon congenital ichthyoses often benefit from interdisciplinary management which involves specialized dermatological centers...
Ichthyoses - Part 1: Differential diagnosis of vulgar ichthyoses and therapeutic optionsMarkus Krug
Department of Dermatology, University of Tubingen, Germany
J Dtsch Dermatol Ges 7:511-9. 2009..In this first part of the paper the vulgar ichthyoses as well as the diagnostic and therapeutic options are discussed. The second part focuses on the congenital ichthyoses and their differential diagnosis...
The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humansKarin Loser
Department of Dermatology, University of Munster, Munster, Germany
PLoS ONE 5:e8958. 2010....
Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cellsMarkus Bohm
Department of Dermatology, University of Munster, Von Esmarch Str 58, D 48149 Munster, Germany
Endocrinology 146:4635-46. 2005....
SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminasesMichael Raghunath
Department of Dermatology, University Hospital, University of Munster, Von Esmarch Strasse 58, D 48149 Munster, Germany
J Invest Dermatol 123:474-83. 2004....
Loss-of-function variants of the filaggrin gene are not major susceptibility factors for psoriasis vulgaris or psoriatic arthritis in German patientsUlrike Huffmeier
Institute of Human Genetics, University Erlangen Nuremberg, Erlangen, Germany
J Invest Dermatol 127:1367-70. 2007..The abnormal staining might reflect the altered epidermal differentiation. Our findings imply that the genetic background underlying the epidermal barrier defect in psoriasis is distinct from that found in atopic dermatitis...
The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiationChristoph Becker-Pauly
Institute of Zoology, Johannes Gutenberg University, Johannes von Müller Weg 6, Mainz, Germany
J Invest Dermatol 127:1115-25. 2007....
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasiaKarl Heinz Grzeschik
Department of Human Genetics, University of Marburg, Bahnhofstr 7, 35033 Marburg, Germany
Nat Genet 39:833-5. 2007..The findings implicate FDH as a developmental disorder caused by a deficiency in PORCN...
