Patricia Ohrmann

Summary

Country: Germany

Publications

  1. doi request reprint Learning potential on the WCST in schizophrenia is related to the neuronal integrity of the anterior cingulate cortex as measured by proton magnetic resonance spectroscopy
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Germany
    Schizophr Res 106:156-63. 2008
  2. doi request reprint Effect of gender on processing threat-related stimuli in patients with panic disorder: sex does matter
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Depress Anxiety 27:1034-43. 2010
  3. ncbi request reprint Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study
    Patricia Ohrmann
    University of Muenster, Department of Psychiatry, Albert Schweitzer Str 11, Germany
    Schizophr Res 73:153-7. 2005
  4. ncbi request reprint Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48149 Muenster, NRW, Germany
    J Psychiatr Res 41:625-34. 2007
  5. ncbi request reprint Proton magnetic resonance spectroscopy in anorexia nervosa: correlations with cognition
    Patricia Ohrmann
    University of Munster, Department of Psychiatry, Albert Schweitzer Str 11, 48129 Munster, Germany
    Neuroreport 15:549-53. 2004
  6. ncbi request reprint Threat sensitivity as assessed by automatic amygdala response to fearful faces predicts speed of visual search for facial expression
    Patricia Ohrmann
    Department of Psychiatry, University of Munster, Albert Schweitzer Street 11, 48149, Muenster, Germany
    Exp Brain Res 183:51-9. 2007
  7. doi request reprint Influence of the catechol-O-methyltransferase val158met genotype on amygdala and prefrontal cortex emotional processing in panic disorder
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, D 48143 Muenster, Germany
    Psychiatry Res 163:13-20. 2008
  8. doi request reprint Neuropeptide Y (NPY) gene: Impact on emotional processing and treatment response in anxious depression
    Katharina Domschke
    Dept of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 20:301-9. 2010
  9. doi request reprint Individual differences in alexithymia and brain response to masked emotion faces
    Maraike Reker
    Department of Psychiatry, University of Munster, Germany
    Cortex 46:658-67. 2010
  10. doi request reprint Increased amygdala activation during automatic processing of facial emotion in schizophrenia
    Astrid Veronika Rauch
    Department of Psychiatry, School of Medicine, University of Muenster, Albert Schweitzer Str 11, Muenster, Germany
    Psychiatry Res 182:200-6. 2010

Detail Information

Publications53

  1. doi request reprint Learning potential on the WCST in schizophrenia is related to the neuronal integrity of the anterior cingulate cortex as measured by proton magnetic resonance spectroscopy
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Germany
    Schizophr Res 106:156-63. 2008
    ..The neurobiological basis of cognitive remediation has not been elucidated so far, although structural, functional and metabolic abnormalities of the prefrontal cortex have been associated with cognitive impairment...
  2. doi request reprint Effect of gender on processing threat-related stimuli in patients with panic disorder: sex does matter
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Depress Anxiety 27:1034-43. 2010
    ..g. panic disorder (PD)...
  3. ncbi request reprint Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study
    Patricia Ohrmann
    University of Muenster, Department of Psychiatry, Albert Schweitzer Str 11, Germany
    Schizophr Res 73:153-7. 2005
    ..Reduced metabolite levels were not correlated with duration of illness or medication. Our results indicate glutamatergic dysfunction in chronic schizophrenia that could be evidence of a progressive brain disorder...
  4. ncbi request reprint Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48149 Muenster, NRW, Germany
    J Psychiatr Res 41:625-34. 2007
    ....
  5. ncbi request reprint Proton magnetic resonance spectroscopy in anorexia nervosa: correlations with cognition
    Patricia Ohrmann
    University of Munster, Department of Psychiatry, Albert Schweitzer Str 11, 48129 Munster, Germany
    Neuroreport 15:549-53. 2004
    ..Our results provide evidence for cognitive impairment in AN patients which is associated with cerebral metabolism in the prefrontal cortex...
  6. ncbi request reprint Threat sensitivity as assessed by automatic amygdala response to fearful faces predicts speed of visual search for facial expression
    Patricia Ohrmann
    Department of Psychiatry, University of Munster, Albert Schweitzer Street 11, 48149, Muenster, Germany
    Exp Brain Res 183:51-9. 2007
    ..Neurobiologically defined threat sensitivity seems to represent an important determinant of visual scanning behaviour...
  7. doi request reprint Influence of the catechol-O-methyltransferase val158met genotype on amygdala and prefrontal cortex emotional processing in panic disorder
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, D 48143 Muenster, Germany
    Psychiatry Res 163:13-20. 2008
    ..This COMT variant might increase the vulnerability to panic disorder by modulating dopaminergic tonus in relevant brain regions and thus altering neuronal processing of anxiety-related emotional cues...
  8. doi request reprint Neuropeptide Y (NPY) gene: Impact on emotional processing and treatment response in anxious depression
    Katharina Domschke
    Dept of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 20:301-9. 2010
    ..The present results point towards a possible influence of functional NPY gene variation on antidepressant treatment response in anxious depression, potentially conveyed by altered emotional processing...
  9. doi request reprint Individual differences in alexithymia and brain response to masked emotion faces
    Maraike Reker
    Department of Psychiatry, University of Munster, Germany
    Cortex 46:658-67. 2010
    ....
  10. doi request reprint Increased amygdala activation during automatic processing of facial emotion in schizophrenia
    Astrid Veronika Rauch
    Department of Psychiatry, School of Medicine, University of Muenster, Albert Schweitzer Str 11, Muenster, Germany
    Psychiatry Res 182:200-6. 2010
    ..Heightened automatic amygdala responsivity could be involved in the development and maintenance of negative symptoms in schizophrenia...
  11. doi request reprint Reduced amygdala-prefrontal coupling in major depression: association with MAOA genotype and illness severity
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 12:11-22. 2009
    ..We conclude that genetic variation in the MAOA gene may affect the course of major depression by disrupting cortico-limbic connectivity...
  12. doi request reprint Automatic mood-congruent amygdala responses to masked facial expressions in major depression
    Thomas Suslow
    Department of Psychiatry, University of Munster, 48149 Munster, Germany
    Biol Psychiatry 67:155-60. 2010
    ..Assessing neurobiological substrates of automatic emotion processing might be a more sensitive challenge for automatic negative bias in depression than behavioral measures...
  13. doi request reprint Neural activation underlying acute grief in women after the loss of an unborn child
    Anette Kersting
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, Muenster, Germany
    Am J Psychiatry 166:1402-10. 2009
    ..Increasing evidence supports the hypothesis that the same neural structures involved in the experience of physical pain are involved in the experience of social pain and loss...
  14. doi request reprint Alexithymic features and automatic amygdala reactivity to facial emotion
    Harald Kugel
    Department of Clinical Radiology, University of Munster, Munster, Germany
    Neurosci Lett 435:40-4. 2008
    ..Low spontaneous reactivity of the amygdala to sad faces could implicate less engagement in the encoding of negative emotional stimuli...
  15. doi request reprint Theory of mind in patients with schizophrenia: is mentalizing delayed?
    Anya Pedersen
    Department of Psychology, University of Muenster, Germany
    Schizophr Res 137:224-9. 2012
    ..Because behavioral studies have revealed slower ToM performance reaction times in patients with schizophrenia, we hypothesized that time would influence functional MRI (fMRI) activation patterns also...
  16. doi request reprint Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Albert Schweitzer Str 11, 48149 Munster, Germany
    Neuroimage 53:893-8. 2010
    ..We conclude that 5-HTTLPR genotype predominantly impacts the central processing predominantly of negative environmental cues but not of emotionally salient stimuli in general...
  17. ncbi request reprint 5-HTTLPR biases amygdala activity in response to masked facial expressions in major depression
    Udo Dannlowski
    1 1Department of Psychiatry, University of Munster, Munster, Germany 2 2IZKF Research Group 4, IZKF Münster, University of Munster, Munster, Germany
    Neuropsychopharmacology 33:418-24. 2008
    ..This might indicate that genetic variations of the serotonin transporter could increase the risk for depression chronification via altering limbic neural activity on a preattentive level of emotion processing...
  18. doi request reprint Attachment avoidance modulates neural response to masked facial emotion
    Thomas Suslow
    Department of Psychiatry, University of Munster, Munster, Germany
    Hum Brain Mapp 30:3553-62. 2009
    ..Our data are consistent with the idea that people who withdraw from close relationships respond spontaneously to a lesser extent to negative interpersonal emotional signals than securely attached individuals...
  19. pmc Amygdala reactivity to masked negative faces is associated with automatic judgmental bias in major depression: a 3 T fMRI study
    Udo Dannlowski
    Dannlowski, Ohrmann, Bauer, Arolt, Kersting, Suslow Department of Psychiatry, University of Munster, Germany
    J Psychiatry Neurosci 32:423-9. 2007
    ..In the present study, we extended the paradigm to a sample of 35 inpatients suffering from depression to investigate the effect of amygdala reactivity on automatic negative judgmental bias and clinical characteristics in depression...
  20. ncbi request reprint Finding of abnormal scanning behavior in the Span of Apprehension task in schizophrenia but diagnostic non-specificity of sum scores
    Katja Koelkebeck
    Department of Psychiatry, School of Medicine, University of Muenster, Albert Schweitzer Strasse 11, 48149 Muenster, Westphalia, Germany
    Eur Psychiatry 23:29-32. 2008
    ..The task was administered to 47 schizophrenia and 48 depressed patients as well as to 46 controls. Results indicate a non-specificity of the SOA sum scores but differential abnormalities in spatial visual processing...
  21. doi request reprint Memory impairment correlates with increased S100B serum concentrations in patients with chronic schizophrenia
    Anya Pedersen
    University Medical Faculty, Department of Psychiatry, 48149 Munster, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:1789-92. 2008
    ..The findings support the hypothesis that astrocyte activation might contribute to the development of cognitive dysfunction in schizophrenia...
  22. doi request reprint Cannabinoid receptor 1 (CNR1) gene: impact on antidepressant treatment response and emotion processing in major depression
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 18:751-9. 2008
    ..This analysis provides preliminary support for a role of CNR1 gene variation in depression and anxiety, potentially mediated by subcortical hypo-responsiveness to social reward stimuli...
  23. doi request reprint Theory of Mind in first-episode schizophrenia patients: correlations with cognition and personality traits
    Katja Koelkebeck
    Department of Psychiatry, University of Muenster, School of Medicine, Albert Schweitzer Strasse 11, 48149 Muenster, Germany
    Schizophr Res 119:115-23. 2010
    ..The aim of our study was to investigate ToM abilities in first-episode schizophrenia patients and to analyze them in relation to neuropsychological and psychopathological functioning...
  24. pmc Neural correlates of set-shifting: decomposing executive functions in schizophrenia
    Andreas Wilmsmeier
    Department of Psychiatry, University of Muenster, Muenster, Germany
    J Psychiatry Neurosci 35:321-9. 2010
    ..We investigated the neural correlates of this mechanism by means of functional magnetic resonance imaging (fMRI) in patients with schizophrenia and healthy controls...
  25. doi request reprint Discriminating unipolar and bipolar depression by means of fMRI and pattern classification: a pilot study
    Dominik Grotegerd
    Department of Psychiatry, University of Munster, Albert Schweitzer Campus 1 A9, 48149, Munster, Germany
    Eur Arch Psychiatry Clin Neurosci 263:119-31. 2013
    ..However, since the present approach deals with small sample sizes, it should be considered as a proof-of-concept study. Hence, results have to be confirmed in larger samples preferably of unmedicated subjects...
  26. doi request reprint Anterior cingulate cortex activation is related to learning potential on the WCST in schizophrenia patients
    Anya Pedersen
    Department of Psychiatry, School of Medicine, University of Muenster, Germany
    Brain Cogn 79:245-51. 2012
    ..Also, our results support the hypothesis that compensatory neural activation in patients with schizophrenia helps them to catch up with healthy controls on cognitive tasks...
  27. ncbi request reprint Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex
    Nikolaus Michael
    University of Muenster, 48129 Munster, Germany
    Psychopharmacology (Berl) 168:344-6. 2003
    ..The dorsolateral prefrontal cortex (DLPFC) participates in the pathophysiology of mania. In particular, left-sided structural and metabolic abnormalities have been described...
  28. ncbi request reprint Amygdala reactivity predicts automatic negative evaluations for facial emotions
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Albert Schweitzer Str 11, 48149 Munster, Germany
    Psychiatry Res 154:13-20. 2007
    ..This finding might shed some light on how amygdala hyperresponsivity contributes to negative cognitive biases commonly observed in affective disorders...
  29. ncbi request reprint Association of the functional -1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder
    Katharina Domschke
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 9:349-55. 2006
    ..These serotonergic polymorphisms might increase the risk for panic disorder by contributing to an altered processing of emotional stimuli...
  30. ncbi request reprint Cognitive coping style modulates neural responses to emotional faces in healthy humans: a 3-T FMRI study
    Astrid Veronika Rauch
    Department of Psychiatry, University of Munster, Munster, Germany
    Cereb Cortex 17:2526-35. 2007
    ..An increased responsivity of the amygdala to ambiguously threatening stimuli may represent a biological determinant of sensitizers' feelings of uncertainty...
  31. ncbi request reprint Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients
    Bettina Pfleiderer
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Psychiatry Res 122:185-92. 2003
    ..04) and then did not differ statistically from controls. Severe depression seems to be associated with a Glx deficit and increasing Glx may be an important mechanism of ECT action...
  32. pmc High responsivity to threat during the initial stage of perception in repression: a 3 T fMRI study
    Victoria Gabriele Paul
    Department of Psychiatry, University of Munster, Albert Schweitzer Campus, Germany
    Soc Cogn Affect Neurosci 7:980-90. 2012
    ..The present results are in line with the vigilance-avoidance theory which predicts heightened automatic responsivity to threatening stimuli in repression...
  33. doi request reprint Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Albert Schweitzer Strasse 11, Munster, Germany
    Biol Psychiatry 71:286-93. 2012
    ....
  34. ncbi request reprint Detection of facial expressions of emotions in schizophrenia
    Thomas Suslow
    Department of Psychiatry, School of Medicine, University of Munster, Albert Schweitzer Str 11, Munster 48149, Germany
    Schizophr Res 64:137-45. 2003
    ..Potential explanations of the face processing effects found in anhedonia are discussed...
  35. ncbi request reprint Amygdala activation during masked presentation of emotional faces predicts conscious detection of threat-related faces
    Thomas Suslow
    Department of Psychiatry, University of Munster, 48149 Munster, Germany
    Brain Cogn 61:243-8. 2006
    ..The present findings underscore the role of the amygdala in the detection and consolidation of memory for marginally perceptible threatening facial expression...
  36. ncbi request reprint Glial cell activation in a subgroup of patients with schizophrenia indicated by increased S100B serum concentrations and elevated myo-inositol
    Matthias Rothermundt
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, D 48301 Muenster, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 31:361-4. 2007
    ..Patients with increased S100B levels showed elevated myo-inositol concentrations. This pilot study demonstrates a concomitant elevation of two markers indicating astrocyte activation in a subgroup of schizophrenic patients...
  37. ncbi request reprint Reduced implicit and explicit sequence learning in first-episode schizophrenia
    Anya Pedersen
    Department of Psychiatry, School of Medicine, University of Muenster, Germany
    Neuropsychologia 46:186-95. 2008
    ..This deficit would be consistent with a fronto-striatal dysfunction and might constitute a crucial factor for the acquisition of new information...
  38. doi request reprint Impact of gray matter reductions on theory of mind abilities in patients with schizophrenia
    Katja Koelkebeck
    a Department of Psychiatry and Psychotherapy, School of Medicine, University of Muenster, Muenster, Germany
    Soc Neurosci 8:631-9. 2013
    ..Our findings confirm that divergent brain regions contribute to mentalizing abilities and that GM volume reductions impact behavioral deficits in patients with schizophrenia. ..
  39. doi request reprint High-level, but not low-level, motion perception is impaired in patients with schizophrenia
    Farid I Kandil
    Institute of Psychology, University of Muenster, Muenster, Germany
    Neuropsychology 27:60-8. 2013
    ..In contrast, data from low-level motion detectors in the primary visual cortex (V1) have been inconsistent...
  40. doi request reprint Complicated grief in patients with unipolar depression
    Anette Kersting
    Department of Psychiatry, University of Muenster, Germany
    J Affect Disord 118:201-4. 2009
    ..Further, the study was aimed to identify characteristics predicting a complicated grief reaction in depressed patients...
  41. ncbi request reprint Neurotrophic effects of electroconvulsive therapy: a proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression
    Nikolaus Michael
    Department of Psychiatry, University of Munster, Germany
    Neuropsychopharmacology 28:720-5. 2003
    ..In conclusion, our preliminary finding of increased NAA concentrations after successful ECT may indicate a probable neurotrophic effect of ECT...
  42. ncbi request reprint The experience of basic emotions in schizophrenia with and without affective negative symptoms
    Thomas Suslow
    Department of Psychiatry, School of Medicine, University of Munster, Germany
    Compr Psychiatry 44:303-10. 2003
    ..Anhedonic patients manifested more emotion inhibition than healthy controls and exhibited an affectivity pattern consistent with Meehl's model of anhedonia...
  43. doi request reprint Dopamine D₃ receptor gene variation: impact on electroconvulsive therapy response and ventral striatum responsiveness in depression
    Udo Dannlowski
    Department of Psychiatry, University of Muenster, Germany
    Int J Neuropsychopharmacol 16:1443-59. 2013
    ..002; sample 2: p=0.023). In summary, the present study suggests some impact of DRD3 gene variation on ECT response, potentially mediated by alteration of striatal engagement during the processing of emotionally rewarding stimuli...
  44. doi request reprint Psychological impact on women after second and third trimester termination of pregnancy due to fetal anomalies versus women after preterm birth--a 14-month follow up study
    Anette Kersting
    Department of Psychiatry, University of Muenster, Munster, Germany
    Arch Womens Ment Health 12:193-201. 2009
    ..The short-term emotional reactions to TOP in late pregnancy due to fetal anomaly appear to be more intense than those to preterm birth. Both events can lead to severe psychiatric morbidity with a lasting psychological impact...
  45. doi request reprint Automatic amygdala response to facial expression in schizophrenia: initial hyperresponsivity followed by hyporesponsivity
    Thomas Suslow
    Department of Psychiatry, University of Munster, Albert Schweitzer Str, 11, Munster 48149, Germany
    BMC Neurosci 14:140. 2013
    ..In addition, we expected amygdala deactivation in response to masked facial emotions from the first to the second phase to be more pronounced in patients than in controls...
  46. pmc Acute shift in glutamate concentrations following experimentally induced panic with cholecystokinin tetrapeptide--a 3T-MRS study in healthy subjects
    Peter Zwanzger
    Mood and Anxiety Disorders Research Unit, Department of Psychiatry and Psychotherapy, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 38:1648-54. 2013
    ....
  47. pmc Craving in alcohol-dependent patients after detoxification is related to glutamatergic dysfunction in the nucleus accumbens and the anterior cingulate cortex
    Jochen Bauer
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 38:1401-8. 2013
    ....
  48. doi request reprint Transcultural differences in brain activation patterns during theory of mind (ToM) task performance in Japanese and Caucasian participants
    Katja Koelkebeck
    Department of Psychiatry, School of Medicine, University of Munster, Munster, Germany
    Soc Neurosci 6:615-26. 2011
    ..To date, however, little is known about transcultural differences in neural activation patterns as they relate to ToM functioning...
  49. ncbi request reprint Visual backward masking: deficits in locating targets are specific to schizophrenia and not related to intellectual decline
    Katja Koelkebeck
    Department of Psychiatry, School of Medicine, University of Muenster, Albert Schweitzer Strasse 11, 48149, Muenster, Germany
    Schizophr Res 78:261-8. 2005
    ..Potential explanations of the location masking deficit found in schizophrenia are discussed...
  50. ncbi request reprint [Measures of grief--a critical review]
    Anette Kersting
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitätsklinikum Muenster
    Psychother Psychosom Med Psychol 53:475-84. 2003
    ..In conclusion, the demands to be made on an instrument to be developed in the future are outlined...
  51. ncbi request reprint [Therapeutic factors of outpatient group psychotherapy - the predictive validity of the Group Experience Questionnaire (GEQ)]
    Anette Kersting
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitätsklinik Münster
    Psychother Psychosom Med Psychol 52:294-301. 2002
    ..Contrary to former investigations the therapeutic factor "cohesion" was less important, which could hint at the fact that a medium amount of cohesion might be sufficient for an effective process of treatment...
  52. ncbi request reprint Outpatient psychotherapy for mothers--first empirical results
    Anette Kersting
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, 48129 Muenster, Germany
    Psychiatry 66:335-45. 2003
    ..First empirical results show that the presented treatment concept led to significant improvements in the symptoms, whose stabilization continued up to the follow-up two years after the start of therapy...
  53. ncbi request reprint Dissociative disorders and traumatic childhood experiences in transsexuals
    Anette Kersting
    Department of Psychiatry, University of Muenster, D 48129 Muenster, Germany
    J Nerv Ment Dis 191:182-9. 2003
    ....